• Journal of Families and Better Life
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• v.29 no.2
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• pp.73-87
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• 2011

The purpose of this study is to investigate the influence of children's socia-demographic variables(i.e., gender, birth order, and the amount of time staying in kindergarten) on, leadership, self-regulation and children's peer play behaviors. The participants of this study are 336 children aged between five and seven in four classes in a private kindergarten and eight classes in a private preschool located in the capital region. The results revealed that, girls showed more leadership, self-regulation, and play interaction section than boys: whereas, boys showed higher response in play disruption and the lack of play disconnection. However, birth order, did not have a significant effect on the sub-domain of leadership, self-regulation competence, and peer play behaviors. As for the duration children stay in preschool or in preschool or kindergarten, children who spend half-day showed higher reaction in behavioral self-control and emotional taking abilities than children who stay in the preschool or kindergarten full day. On the other hand, self-esteem of full-time children was higher than half-time children. Children who were emotionally sensitive, knew how to lead their peer group, and those who were sociable and self-regulated presented to be more active in peer-interaction than others. Second, as the result of the correlation analysis reveals, children's leadership, self-regulation competence, peer play behaviors, and play interaction had a meaningful effect on the sub-variations of children's leadership and self-regulation and they showed significant influence upon play disruption and play disconnection. In addition, girls who were not able to manage or to inspect their behavior and had insensitive emotion demonstrated higher tendency to play disconnected. Children, who participated in full-day program with having difficulties in self-regulation or inspecting their behavior properly but had a strong leadership and insensitive showed play disruption highly.

• Journal of the Korean Society for Computer Game
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• v.31 no.4
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• pp.1-8
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• 2018

The present study investigated the validity of a serious game named 'Draw Ttoring' developed for accessment of children's attention and tried to provide the basic information about it. To this goal, we tested it to 284 elementary school students in measuring various behavior data(reaction time, total playing time, correct rate, discrepancy between type of TMT). Futhermore, the behavior data was compared with academic achievement to see the external validity. In results, 'Draw Ttoring' showed various behavior data and correlation with academic achievement. In Type A of TMT, total time and reaction time had a correlation with academic achievement, while, in Type B of TMT, total time and correct rate did. Mental flexibility calculated by the discrepancy between Type A and Type B showed also the positive correlation with academic achievement. These results showed that the serious game named 'Draw Ttoring' can provide more various information about children attention and these can't be observed by traditional paper pencil test. Finally, serious game can provide an good alternative method to access children's cognition.

• Korean Journal of Social Welfare
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• v.40
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• pp.5-37
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• 2000

The purpose of this study is to find out some characteristics of the family functions of single mothers to provide some useful data for the development of programs which may help single mothers to improve their family functions. The McMaster Family Assessment Device (FAD) which is composed of problem solving function (PS), communication function (CF), role function (RC), emotional reaction function (ER), emotional involvement (EI), behavioral control function (BC), and general function (GC) and McCubbins' FSI were administered to single mothers and their adolescent children and mothers and their adolescent children of ordinary families (control family). The single mothers' perception of their family function was lower than that of control family mothers in an the 7 categories of FAD. The perceptions of the family function of the single mothers' children were lower than those of control family mothers' children. There was on significant difference between the perceptions of single mothers and their children in PS, ER, EI, GC of their family. However, single mothers' perception in RC and BC was lower than that of their children, and the children's perception in CF were lower than that of their mothers. Single mothers who fall on the period of single motherhood was shorter than 7 years perceived their families' function as lower than that of single mothers' who fall on the periods of single motherhood longer than 7 years in all categories. Generally speaking, the single mothers' family functions were lower than that of control family. The different characteristics of each single mother's family functions should be considered in developing programs for single mothers.

• Journal of the Korean Home Economics Association
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• v.34 no.2
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• pp.31-42
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• 1996

The purpose of this study was to examine the mother's perception on the concrete pattern of such behavior problems as noncompliance, jealousy, dependency, hyperactivity and stealing, by analyzing the difference between two cases of her own child and another mother's child relating to her attribution to the behavior problem of the child and the relationship between her attribution and behavioral reaction. This study was carried out by using 515 questionnaires answered by 1000 mothers of children of 7 kindergartens in Ulsan and Taegu, using Melissa Sweitzer's method (1986). The data was subjected to t-test, Pearson's correlation coefficient. T-test was applied to test the difference between two cases of her own child and another mother's child relating to her attribution to the behavior problem of the child and Person's correlation coefficient was estimated to test the relationship between her attribution and behavioral reaction. The result of this study is sumarized as follows : 1. It was shown that the mother's attribution to the behavior problem of the child is less serious when her child showed the behavior problem than when another child dose the problem while her attribution has an affective reaction to the behavior problem of the child. 2. The relationship between the mother's attribution and behavior reaction to the behavior problem of the child appeared variously in accordance with the attribution factor and behavior problem. Then the mother showed more attribution to stability while frequently ignoring the child.

• Journal of Genetic Medicine
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• v.13 no.1
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• pp.36-40
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• 2016

Tuberous sclerosis complex (TSC, MIM#191100) is an autosomal dominant neurocutaneous syndrome caused by mutation or deletion of TSC1 encoding hamartin or TSC2 encoding tuberin and characterized by seizure, mental retardation, and multiple hamartomas or benign tumors in the skin, brain, retina, heart, kidney, and lungs. The TSC2 gene on chromosome 16p13.3 lies adjacent to the PKD1 gene which is responsible for autosomal dominant polycystic kidney disease (MIM#173900). The TSC2/PKD1 contiguous gene syndrome (TSC2/PKD1 CGDS, MIM#600273) is caused by deletion of both TSC2 and PKD1 gene. We recently experienced a 15 month-old boy and a 26 month-old girl with TSC2/PKD1 CGDS confirmed by multiplex ligation-dependent probe amplification (MLPA) analysis. They showed not only typical neurologic manifestations of TSC such as epilepsy, subependymal nodules, and subcortical tubers, but also polycystic kidney disease. The contiguous gene syndrome involving PKD1 and TSC2 should be suspected in children with enlarged polycystic kidneys and TSC. MLPA analysis is a useful method for the genetic confirmation of TSC2/PKD1 CGDS.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.5 no.1
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• pp.184-193
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• 1994

This study was purposed to find out clinical characteristic of intra and extrafamilial sexual abuse, nature of offenders, difference of symptoms describe that sexually abused children and adolescents were experienced. Subjects were 10 sexually abused children and adolescents who visited Seoul National Mental Hospital, from Jan. 1992 to Dec. 1993. In intrafamilial sexual abuse, they had more chronic course than extrafamilial abuse and had more family psychopathology. In symptomatology, The preschool children mainly presented to somatic symptoms and anxiety, and The school children prominently exhibited depressive reaction and withdrawal. Most common reaction of parents was anger and guilt. They were treated with crisis intervention, play therapy, and hospitalization, if needed. The maintenance of treatment was difficult due to parent's avoidance and repression.

• Journal of Families and Better Life
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• v.29 no.6
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• pp.55-69
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• 2011

The purpose of this study was to explore the effects of difficult temperament and mothers' reactions to child negative emotion on child emotion regulation strategies. Mothers of 253 preschoolers(Mage=4.04yrs.) responded to questionnaires on child temperament, mothers' reactions to child negative emotion, and child emotion regulation strategy. The results of regression analysis revealed that; 1) child difficult temperament positively predicted child's aggressive or outburst/appealing strategies whereas negatively predicted avoidance/none strategy; 2) child difficult temperament was not the variable predicting positive coping strategy, but mothers' emotion-focused or problem-focused reactions predicted child positive coping strategy whereas punitive or distress reactions predicted either aggressive or avoidance/none strategy; 3) child temperament moderated the link between mothers' reactions to child's negative emotion expression and child emotion regulation strategies. In particular, children with higher difficult temperament showed higher aggressive strategy under mothers' higher distress or punitive reaction and lower emotion focused or problem focused reaction. On the other hand, children with lower difficult temperament only showed avoidance/ none strategy when mothers showed higher minimization or punitive reaction. The results of current study underscore both child temperament, mothers' reactions and their interactions in predicting child emotion regulation strategies.

• Archives of design research
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• v.18 no.1 s.59
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• pp.263-272
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• 2005

The layout in picture book is a visual statement that arouses children's psychological reaction upon pictorial positions and those disposition, and that indicates a correlation between theme and background and characters' movements. This study firstly confirmed that children's perception and experience are variously formed according to age, past experience, psychological action, physiological impulse, mentality, growth environment, etc., in order to analyze how the pictorial layout in children's picture book has influence on children visually and psychologically. Likewise, visual and psychological perception was carried out targeting on the children between 4 and 7 years old, based on the perceptive specific and process that have been studied by previous researchers. In addition, the children's picture books published overseas or domestically were presented as the related cases, in order that the facts analyzed may be drawn to harmonious and effective pictorial layout. Lastly, it is expected that the conclusion suggested by this study may be of help to illustrators to design picture books individually and creatively, as well as be applied to studying effective expression in the educant who learn about illustration.

• Korean Journal of Child Studies
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• v.37 no.4
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• pp.101-115
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• 2016

Objective: The study examined the mediated-moderation effect of social-support levels from maternal-acceptance experiences by the parents of origin to child emotion regulation strategies through an emotion-coaching reaction. Methods: The participants in this study were children (Grades 4-6) and their mothers. They completed questionnaires on Maternal Parenting Experiences Scale, Children's Emotion Regulation Scale, Emotion-Coaching Scale, and Social Supportive Level Scale. Data were analyzed via SEM. Results: The main findings were as follows. First, a mediating model showed that the relationship between maternal-acceptance experiences by the parents of origin and child emotion-regulation strategies was mediated by emotion-coaching reactions. Second, there was a moderation effect of social-supportive levels on the relationship between maternal-acceptance experiences from parents of origin and emotion-coaching reaction. Finally, social-supportive levels mediated the moderation effect of social-support level from maternal-acceptance experiences to child emotion-regulation strategies through emotion-coaching reaction. Conclusion: These results indicate that importance of maternal social-supportive level from owns spouse or friends. I discussed the implications of the intervention of parent counseling and parent education in this research.

• Journal of Korean Neurosurgical Society
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• v.66 no.6
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• pp.642-651
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• 2023

Objective : Endothelial colony-forming cells (ECFCs) have been reported to play an important role in the pathogenesis of moyamoya disease (MMD). We have previously observed stagnant growth in MMD ECFCs with functional impairment of tubule formation. We aimed to verify the key regulators and related signaling pathways involved in the functional defects of MMD ECFCs. Methods : ECFCs were cultured from peripheral blood mononuclear cells of healthy volunteers (normal) and MMD patients. Low-density lipoproteins uptake, flow cytometry, high content screening, senescence-associated β-galactosidase, immunofluorescence, cell cycle, tubule formation, microarray, real-time quantitative polymerase chain reaction, small interfering RNA transfection, and western blot analyses were performed. Results : The acquisition of cells that can be cultured for a long time with the characteristics of late ECFCs was significantly lower in the MMD patients than the normal. Importantly, the MMD ECFCs showed decreased cellular proliferation with G1 cell cycle arrest and cellular senescence compared to the normal ECFCs. A pathway enrichment analysis demonstrated that the cell cycle pathway was the major enriched pathway, which is consistent with the results of the functional analysis of ECFCs. Among the genes associated with the cell cycle, cyclin-dependent kinase inhibitor 2A (CDKN2A) showed the highest expression in MMD ECFCs. Knockdown of CDKN2A in MMD ECFCs enhanced proliferation by reducing G1 cell cycle arrest and inhibiting senescence through the regulation of CDK4 and phospho retinoblastoma protein. Conclusion : Our study suggests that CDKN2A plays an important role in the growth retardation of MMD ECFCs by inducing cell cycle arrest and senescence.