• 제목/요약/키워드: Channel effect

검색결과 3,524건 처리시간 0.052초

Paeonol의 잠재적인 항부정맥 효과의 컴퓨터 시뮬레이션 연구 (Computer Simulation Study of the Potential Anti-arrhythmic Properties of Paeonol)

  • 이수진
    • 동의생리병리학회지
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    • 제29권4호
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    • pp.305-312
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    • 2015
  • Paeonol is a major component found in the Paeoniaceae family such as Paeonia suffruticosa Andrews. Paeonia suffruticosa Andrews has traditionally been used to enhance blood flow and relieve joint pain in east Asian countries including China, Korea and Japan. Current research has shown that paeonol blocked the voltage-gated sodium channel and L-type calcium channel. However, there is a lack of research to reveal the relation between cardiac function and blockade of ion channels by paeonol. Therefore, the aim of this study is to investigate whether paeonol has anti-arrhythmic effects via modulating cardiac ion channels. It is collected that the effects of paeonol on multiple ion channels such as the fast sodium channel and L-type calcium channel from published papers. To incorporate the information on multi-channel block, we computed the effects using the mathematical cardiac model of the guinea-pig and rat ventricular cells (Noble 1998 and 1991 model) and induced early after-depolarizations (EADs) to generate an arrhythmia in the whole heart. Paeonol slightly shortened the action potential duration in the normal cardiac ventricular action potential by the inhibition of sodium channel and L-type calcium channel. Paeonol presented the protective effect from EADs by the inactivation of sodium channel but not L-type calcium channel. Paeonol did not show any changes when it treated on normal ventricular cells through the inhibition of sodium channel, but the protective effect of paeonol through sodium channel on EADs was dose-dependent. These findings suggest that paeonol and its original plant may possess anti-arrhythmic activity, which implies their cardioprotective effects.

Y-cut LiNbO$_3$ 양자확산 광도파로를 이용한 전기광학 차단형 광변조기 (Electro-Optic Cutoff Modulator on Y-cut LiNbO$_3$ Proton-Diffused Channel Waveguides)

  • 손영성
    • 한국광학회:학술대회논문집
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    • 한국광학회 1990년도 제5회 파동 및 레이저 학술발표회 5th Conference on Waves and lasers 논문집 - 한국광학회
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    • pp.269-273
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    • 1990
  • The proton conserving effect of diffusion with self-aligned SiO2-cladding is investigated by infrared transmission spectra. Based on the proton conserving effect, proton-diffused channel waveguides with self-aligned SiO2-cladding substrates. And an electro-optic cutoff modulator with self aligned electrode that utilizes a single-mode proton-diffused channel waveguide in a Y-cut XX-propagating LiNbO3 substrate is fabricated. Over 20 dB extinction has been achieved with applied voltage of 15V.

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제습제와 채널이 제습로터 성능에 미치는 영향 (Effect of Desiccant and Channel Geometries on the Performance of Desiccant Rotor)

  • 정재동;이대영;윤석만
    • 설비공학논문집
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    • 제19권8호
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    • pp.569-576
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    • 2007
  • The desiccant rotor is the most essential component of desiccant cooling system, but one of its drawbacks to spread out is rotor size. To reduce the size of rotor the analysis of rotor performance is crucial. Systematic examination on the effect of desiccant and channel geometries has been conducted based on the numerical program previously developed. Considered parameters related to channel geometries are channel shape and cross section area of channel, and parameters related to desiccant are mass fraction, heat capacity, density, maximum water uptake and separation factor of isotherm. Considerable reduction of rotor size is expected by adjusting the parameters.

PEM 연료전지 유로에서 물의 거동에 대한 CFD 해석 (CFD analysis on the behavior of liquid water in flow channel of PEM fuel cell)

  • 김현일;남진현;신동훈;정태용;김영규
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2007년도 추계학술대회 논문집
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    • pp.23-26
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    • 2007
  • Liquid water in flow channel is an important factor that limits the steady and transient performance of PEM fuel cells. A computational fluid dynamics study based on the volume-of-fluid (VOF) multi-phase model is conducted to understand the transport behavior of liquid water in flow channel. The liquid water transport in $180^{\circ}$ bends is investigated and the effect of chamfering is discussed. The effect of wall adhesion is also considered by varying the contact angle of channel surfaces. The result of this study is believed to provide a useful guideline for design optimization of flow patterns or channel configurations of PEM fuel cells.

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Jakes 채널 모델을 이용한 WAVE 통신시스템 성능에 관한 연구 (A Study on the Performance of WAVE Communication System using Jakes Channel Model)

  • 오세갑;최재명;강희조
    • 한국항행학회논문지
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    • 제13권6호
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    • pp.943-949
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    • 2009
  • 본 논문에서는 고속의 무선 채널 환경에 적합한 Jakes 채널 모델을 적용하여 5.9GHz WAVE 무선 채널을 모델링하고, WAVE 통신시스템에 대한 표준화 작업이 진행 중인 IEEE 802.11p 스펙트럼 마스크, 도플러효과, 변조방식에 따른 페이딩 신호 성좌도 및 스펙트럼을 분석한다. 또한 차량속도 즉 도플러 효과에 따른 WAVE 통신시스템의 성능을 분석한다.

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입구 속도 분포가 매끈한 회전유로 내 열전달계수에 미치는 영향 (Effect of Inlet Velocity Distribution on the Heat Transfer Coefficient in a Rotating Smooth Channel)

  • 최은영;이용진;전창수;곽재수
    • 한국유체기계학회 논문집
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    • 제14권6호
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    • pp.76-84
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    • 2011
  • The effect of inlet velocity profile on the heat transfer coefficient in a rotating smooth channel was investigated experimentally. Three simulated inlet flow conditions of fully developed, uniform, and distorted inlet conditions were tested. The Reynolds number based on the channel hydraulic diameter was ranged from 10,000 to 30,000 and the transient liquid crystal technique was used to measure the distribution of the heat transfer coefficient in the rotating channel. Results showed that the overall heat transfer coefficient increased as the Reynolds number increased. Also, the distribution of the heat transfer coefficient was strongly affected by the inlet flow condition. Generally, the fully developed flow simulated condition showed the highest heat transfer coefficient.

Efficient detectors for MIMO-OFDM systems under spatial correlation antenna arrays

  • Guerra, David William Marques;Fukuda, Rafael Masashi;Kobayashi, Ricardo Tadashi;Abrao, Taufik
    • ETRI Journal
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    • 제40권5호
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    • pp.570-581
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    • 2018
  • This work analyzes the performance of implementable detectors for the multiple-input multiple-output (MIMO) orthogonal frequency division multiplexing (OFDM) technique under specific and realistic operation system conditions, including antenna correlation and array configuration. A time-domain channel model was used to evaluate the system performance under realistic communication channel and system scenarios, including different channel correlation, modulation order, and antenna array configurations. Several MIMO-OFDM detectors were analyzed for the purpose of achieving high performance combined with high capacity systems and manageable computational complexity. Numerical Monte Carlo simulations demonstrate the channel selectivity effect, while the impact of the number of antennas, adoption of linear against heuristic-based detection schemes, and the spatial correlation effect under linear and planar antenna arrays are analyzed in the MIMO-OFDM context.

고성능 저전압 모바일향 90nm DRAM을 위한 비대칭 채널구조를 갖는 Recess Channel Array Transistor의 제작 및 특성 (A study of Recess Channel Array Transistor with asymmetry channel for high performance and low voltage Mobile 90nm DRAMs)

  • 김상범;이진우;박양근;신수호;이은철;이동준;배동일;이상현;노병혁;정태영;김길호
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2004년도 추계학술대회 논문집 Vol.17
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    • pp.163-166
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    • 2004
  • 모바일향 90nm DRAM을 개발하기 위하여 비대칭 채널 구조를 갖는 Recess Channel Array Transistor (RCAT)로 cell transistor를 구현하였다. DRAM cell transistor에서 junction leakage current 증가는 DRAM retention time 열화에 심각한 영향을 미치는 요인으로 알려져 있으며, DRAM의 minimum feature size가 점점 감소함에 따라 short channel effect의 영향으로 junction leakage current는 더욱 더 증가하게 된다. 본 실험에서는 short channel effect의 영향에 의한 junction leakage current를 감소시키기 위하여 Recess Channel Array Transistor를 도입하였고, cell transistor의 채널 영역을 비대칭으로 형성하여 data retention time을 증가시켰다. 비대칭 채널 구조을 이용하여 Recess Channel Array Transistor를 구현한 결과, sub-threshold 특성과 문턱전압, Body effect, 그리고, GIDL 특성에는 큰 유의차가 보이지 않았고, I-V특성인 드레인 포화전류(IDS)는 대칭 채널 구조인 transistor 대비 24.8% 정도 증가하였다. 그리고, data retention time은 2배 정도 증가하였다. 본 실험에서 얻은 결과는 향후 저전압 DRAM 개발과 응용에 상당한 기여를 할 것으로 기대된다.

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Channel과 gate 구조에 따른 산화물 박막트랜지스터의 전기적 특성 연구 (Effect of Channel and Gate Structures on Electrical Characteristics of Oxide Thin-Film Transistors)

  • 공희성;조경아;김재범;임준형;김상식
    • 전기전자학회논문지
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    • 제26권3호
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    • pp.500-505
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    • 2022
  • 본 연구에서는 새로운 구조의 dual gate tri-layer split channel 박막트랜지스터를 제작하였다. 전류 구동 능력을 향상시키기 위해 액티브 층의 양쪽에 게이트를 형성하였고 전하이동도를 증가시키기 위하여 액티브 층에서 채널이 형성되는 구간인 첫번째 층과 세번째 층에 전도성이 높은 ITO 층을 배치하였다. 추가적으로 분할 채널을 이용하여 채널의 series 저항을 낮추면서 분할한 채널의 측면에서도 accumulation을 유도하여 전하이동도를 향상시켰다. 기존의 single gate a-ITGZO 박막트랜지스터가 15 cm2/Vs의 전하이동도를 가지는 반면 dual gate tri-layer split channel 박막트랜지스터는 134 cm2/Vs의 높은 전하이동도를 가졌다.

딤플이 설치된 회전 유로의 높이가 열전달 계수에 미치는 영향에 대한 실험적 연구 (Effect of channel height on the heat transfer coefficient of a rotation dimpled channel)

  • 김석범;이용진;최은영;전창수;곽재수
    • 한국유체기계학회 논문집
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    • 제13권3호
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    • pp.30-36
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    • 2010
  • The detailed heat transfer coefficients on a rotating dimpled channel were measured by the hue detection based the transient liquid crystal technique. The dimples were fabricated on the one side of the channel and the tested channel aspect ratio was 4, 6, and 12 with fixed channel width. Tested Reynolds number based on the channel hydraulic diameter was varied from 21,000 to 47,000. A stationary case and two different rotating conditions were tested so that the dimple fabricated surface became leading or trailing surface. For all rotating conditions, the minimum averaged heat transfer coefficient was measured for the channel aspect ratio of 6. Generally, the highest averaged heat transfer coefficient was observed for the highest aspect ratio cases due to increased dimple induced vortex strength.