• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2036-2042
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• 2016

We evaluated the potentials of 10 isothiocyanates (ITCs) from cruciferous vegetables and radish root hydrolysate for inhibiting the growth of oral pathogens, with an emphasis on assessing any structure-function relationship. Structural differences in ITCs impacted their antimicrobial activities against oral pathogens differently. The indolyl ITC (indol-3-carbinol) was the most potent inhibitor of the growth of oral pathogens, followed by aromatic ITCs (benzyl ITC (BITC) and phenylethyl ITC (PEITC)) and aliphatic ITCs (erucin, iberin, and sulforaphene). Sulforaphene, which is similar in structure, but has one double bond, showed higher antimicrobial activity than sulforaphane. Erucin, which has a thiol group, showed higher antimicrobial activity than sulforaphane, which has a sulfinyl group. BITC and iberin with a short chain exhibited higher antimicrobial potential than PEITC and sulforaphane with a longer chain, respectively. ITCs have strong antimicrobial activities and may be useful in the prevention and management of dental caries.

• Applied Microscopy
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• v.48 no.4
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• pp.81-86
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• 2018

The respiratory chain complex forms a supercomplex (SC) in the inner mitochondrial membrane. This complex facilitates the process of electron transfer to produce the proton gradient used to synthesize ATP. Understanding the precise structure of the SC is considered an important challenge. However, it has not yet been reported. The development of a Cryo-electron microscopy (EM) technique provides an effective way to obtain high-resolution micrographs to determine the high-resolution three-dimensional structure of biomolecules. In this brief review, the currently reported Cryo-EM structures of the mammalian respirasome have been described in order to establish a direction for further research in the respiratory system.

• The Journal of Information Systems
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• v.30 no.2
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• pp.127-146
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• 2021

Research Purpose Advances in digital technology have facilitated the widespread adoption of online learning, which has become a substantial way of learning. Although digital immigrants have become a main group of users of learning online, there is a lack of understanding of their online learning. This study aims to explore digital immigrants' adoption of online learning from the goal-pursuit perspective to gain insight into how they use online learning. Research Method A laddering interview was conducted with 22 Korean adults to elicit their goals in online learning. Then, a means-end chain analysis was used to derive their hierarchical goal structure. Findings The results reveal digital immigrants' goal structure of online learning, consisting of four attributes of online learning (e.g., accessibility, diversity, up-to-dateness, and repeatability) and six goals (e.g., self-esteem, enjoyment, recognition, productivity, gaining insights, and positive relations). This study contributes to the literature by providing a rich picture of their use of online learning.

• Korea Journal of Hospital Management
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• v.19 no.3
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• pp.11-28
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• 2014

This study, targeting Korean tertiary hospitals and general hospitals, aims to analyze how value chain model in health and medical institution suggested by Duncan and else influences on hospital management. A survey was conducted to verify the actual proof analysis of this study model. 880 questionnaires were distributed to entire 88 hospitals and 739 copies were returned from 76 hospitals. This study mainly consists of three steps to analyze the effect value chain activity has on management performance of general hospitals. For the first step, we analyzed the effects service delivery activity has on management performance. For the second step, we analyzed the effects service support activity has on management performance and for the third, we analyzed the effects interaction between service delivery activity and service support activity has on management performance. The main results of this study are as follows. First, in terms of the management performance of scale, the factors which influenced on daily charge of outpatient were service activity before treatment, at the moment of treatment and value chain activity, while more important factors in daily charge of inpatient were organizational culture, organizational structure and value chain activity. In terms of management performance of quality, the factors which influenced on the first medical examination rate of outpatient were service activity before, at the moment of and after treatment, while activity at the moment of treatment, organizational structure, and value chain activity which is interaction were more important factors in average length of stay. In terms of non-financial performance, the management performance factors which influenced on job satisfaction were service activity at the moment of, after the treatment and value chain activity, while organizational culture, strategy resources and value chain activity which is interaction were more important factors in job commitment. Secondly, all the service support activity, service delivery activity and value chain activity had statistically significant effect on management performance. Among the three factors, service support activity had relatively high effect than others.

• Bulletin of the Korean Chemical Society
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• v.33 no.9
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• pp.2917-2924
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• 2012

Four novel metal-organic complexes $[Cd_2(IP)_2(TBZ)_2(H_2O)_2]{\cdot}(H_2O)$ (1), $[Zn_4(IP)_4(TBZ)_4]{\cdot}2(H_2O)$ (2), $[Zn_2(BTC)(TBZ)_2(CO_2H)]$ (3), [Co(PDC)(TBZ)] (4) (where IP = isophthalate; TBZ = thiabendazole; BTC = 1,3,5-benzenetricarboxylate; PDC = pyridine-3,4-dicarboxylate) have been prepared and characterized by IR spectrum, elemental analysis, thermogravimetric analysis, and single-crystal X-ray diffraction. X-ray structure analysis reveals that 1, 2, and 3 are one-dimensional chain polymers, while 4 is a two-dimensional network polymer. The TBZ acts as a typical chelating ligand coordinated to the metal center in all complexes. The 1D chain architecture of 1 is constructed from isophthalates and cadmium atoms. A simultaneous presence of chelating, monodentate and bidentate coordination modes of IP ligands is observed in complex 2. In complex 3, the 16-membered rings are alternately arranged forming an infinite 1D double-chain structure. The 2D skeleton of 4 is formed by cobalt ions as nodes and PDC dianions as spacers, through coordination bonds. The hydrogen bonds and ${\pi}-{\pi}$ stacking play important roles in affecting the final structure where complexes 1 and 3 have 2D supramolecular networks, while complexes 2 and 4 have 3D supramolecular architectures.

• Journal of Distribution Science
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• v.14 no.4
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• pp.127-134
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• 2016

Purpose - Value chain in agriculture refers to direct and indirect activities related to value-added process from raw materials to final products in agricultural industries. In recent years, value chain analysis has become more important in the area of agricultural development. This article reviews the concept and importance of value chain analysis in the context of agricultural development and attempts to suggest improvement strategies. Research design, data, methodology - A literature survey was conducted for value chain analysis for agricultural development. The case of agro-value chain in Cambodia was deeply analyzed based upon interviews with government officers and related experts. Results - It seems that agro-value chain in developing countries are not well developed and does not carry out appropriate functions, compared to developed countries. Because value adding facilities, such as storage, processing and packing plants, milling plants, and etc. are not sufficiently constructed, the quality of agricultural products is low. Especially developing countries may loose opportunities to increase value of their product by exporting their agricultural products as raw materials to neighboring countries. Value adding process is also mainly controlled by traders in local markets or wholesale markets in urban areas. Farmers therefore can get lower share of final value of agricultural products compared to the shares paid to traders. Lastly it is argued that governments of developing countries do not play an active role in developing value chains and do not carry out coordinating functions in an effective and efficient manner. Conclusions - The first step to improve agro-value chain in developing countries is to identify and analyze value chain structure of agricultural products and to make development strategies and implementation programs. For improving value chain of agricultural products in developing countries, it is required to provide not only plans for constructing hardwares, such as wholesale markets, storage facilities, processing and packing plants, and etc., but also plans for improving softwares, such as measures for improving product quality and safety, setting up grade and standard, providing market information, and nurturing producer cooperatives.

• Korean Journal of Agricultural Science
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• v.45 no.2
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• pp.298-307
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• 2018

The aim of this study was to enhance the value of the chestnut industry by analyzing the value chain structure. Based on the value chain theory, it is divided into primary activities and support activities. Thus, in total, 27 subjects from Gongju, Buyeo, and Cheongyang were interviewed and self-administered questionnaire. Regarding the value chain structure of the chestnut industry, the primary activities consisted of production followed by cultivation and storing, sorting and packaging, transportation and marketing sales. The support activities were divided into production infrastructure, policy, R&D, and systematization. The primary activities are able to maximize profits through cost reductions. The production was divided into general and environmentally friendly cultivation. Depending on the labor force, it is family-centered labor. However, the installation of harvest nets depends on a hired labor force (40 - 60%) such that it would be necessary to have a mechanized harvest to replace the manpower for the cost reduction. Transportation, marketing sales, and backdoor selling (38.1%) were higher than the existing channels (31.0%) using the National Agricultural Cooperative Federation. The enhancement of value could be created by maximizing profits through the reinforcement of the links between each subject. The production showed strong connections with cultivation/storing, sorting/packing, and backdoor selling and the National Forestry Cooperative Federation. The processing stage is a very simple structure, it would be necessary to have R&D and to support promotions, infrastructure, machines, and sales increases, which should be expanded by connections with other industries like the food industry.

• Journal of Korea Multimedia Society
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• v.14 no.5
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• pp.614-621
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• 2011

This paper presents design of a wide tuning range digitally controlled oscillator(DCO) for Mobile-DTV applications. DCO is the key element of the ADPLL block that generates oscillation frequencies. We proposed a binary delay chain(BDC) structure, for wide tuning range DCO, modifying conventional fixed delay chain. The proposed structure generates oscillation frequencies by delay cell combination which has a variable delay time of $2^i$ in the range of $0{\leq}i{\leq}n-1$. The BOC structure can reduce the number of delay cells because it make possible to select delay cell and resolution. We simulated the proposed DCO by Cadence's Spectre RF tool in 1.8V chartered $0.18{\mu}m$ CMOS process. The simulation results showed 77MHz~2.07GHz frequency range and 3ps resolution. The phase noise yields -101dBc/Hz@1MHz at Mobile-DTV maximum frequency 1675MHz and the power consumption is 5.87mW. The proposed DCO satisfies Mobile-DTV standards such as ATSC-M/H, DVB-H, ISDB-T, T-DMB.

• Membrane Journal
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• v.29 no.1
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• pp.37-43
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• 2019

In this study, we investigated how the force-field, which is the most important factor to define atomic motion in molecular dynamics (MD), affects the motion of the polymer and gas molecules. The repeat units and the polymer structure were well simulated in all five force-fields, and the distribution of the polymer linear chain in the final polymer 3D model did not show any significant difference. However, the movement of actual gas molecules showed a very different tendency, which was also observed in COMPASS and pcff using the same functional form. Therefore, even if the same structure is used, it can be seen that the motion of the gas molecule moves under the influence of the force-field continuously over time, so that the effect is much larger than that of macromolecules such as a polymer linear chain. Accordingly, in case of using different force-fields, it is necessary to be very careful in comparison of those results.

• Health Policy and Management
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• v.21 no.2
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• pp.263-278
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• 2011

As the competition among hospitals become intensified, hospital management is required to carry out more effective marketing and positioning of the hospital. Successful positioning of a hospital requires the knowledge about how the concrete attributes inherent in the medical service associated with the customer values that customers seek eventually in the medical service. Thus, it is required for hospital management to understand which hospital attributes should be emphasized in order to improve the customer values. The hierarchical structure of service attributes can provide valuable information about effective positioning and advertising. To obtain such knowledge, we employed the order analysis technique as an objective means-end chain method. Order analysis is useful for identifying the causal structure among attributes. Thus, we can examine the underlying causal relationship and eventually the vertical structure of hospital selection attributes. For this study, we conducted a survey to obtain 370 responses for the analysis. The result suggests that hospital management had better increase the scale of hospital, improve the services of health care providers, and modernize the hospital facilities and equipments so as to enhance customer values and eventually to lead them to recommend the hospital to others. Our findings would provide the valuable information for hospital management to develop the more effective hospital positioning and marketing strategies.