• 제목/요약/키워드: Central functions

검색결과 769건 처리시간 0.023초

The Role of a Neurovascular Signaling Pathway Involving Hypoxia-Inducible Factor and Notch in the Function of the Central Nervous System

  • Kim, Seunghee;Lee, Minjae;Choi, Yoon Kyung
    • Biomolecules & Therapeutics
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    • 제28권1호
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    • pp.45-57
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    • 2020
  • In the neurovascular unit, the neuronal and vascular systems communicate with each other. O2 and nutrients, reaching endothelial cells (ECs) through the blood stream, spread into neighboring cells, such as neural stem cells, and neurons. The proper function of neural circuits in adults requires sufficient O2 and glucose for their metabolic demands through angiogenesis. In a central nervous system (CNS) injury, such as glioma, Parkinson's disease, and Alzheimer's disease, damaged ECs can contribute to tissue hypoxia and to the consequent disruption of neuronal functions and accelerated neurodegeneration. This review discusses the current evidence regarding the contribution of oxygen deprivation to CNS injury, with an emphasis on hypoxia-inducible factor (HIF)-mediated pathways and Notch signaling. Additionally, it focuses on adult neurological functions and angiogenesis, as well as pathological conditions in the CNS. Furthermore, the functional interplay between HIFs and Notch is demonstrated in pathophysiological conditions.

Point Spread Function of Optical Systems Apodized by Semicircular Array of 2D Aperture Functions with Asymmetric Apodization

  • Reddy, Andra Naresh Kumar;Sagar, Dasari Karuna
    • Journal of information and communication convergence engineering
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    • 제12권2호
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    • pp.83-88
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    • 2014
  • The simultaneous suppression of sidelobes and the sharpening of the central peak in the process of diffraction pattern detection based on asymmetric apodization have been investigated. Asymmetric apodization is applied to a semicircular array of two-dimensional (2D) aperture functions, which is a series of 'coded-phase arrays of semicircular rings randomly distributed over the central circular region of a pupil function' and is similar to that used in the field of diffractive optics. The point spread function (PSF) of an imaging system with asymmetric apodization of the discrete type has been found to possess a good side with suppressed sidelobes, whereas its bad side contains enhanced sidelobes. Further, the diffracted field characteristics are obtained in the presence of these aperture functions. Asymmetric apodization is helpful in improving the performance of the optical gratings or 2D arrays used in real-time imaging techniques.

광역 건강가정지원센터의 기능 및 건강가정지원센터 평가 기능에 대한 연구 (The Study on the functions of Metro Healthy-Families-Center and of the Evaluation for Healthy-families-Center)

  • 송혜림;라휘문
    • 가족자원경영과 정책
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    • 제13권3호
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    • pp.1-16
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    • 2009
  • The purpose of this study were to establish the concrete function of Metro Healthy-Families-Center and to find out the function of evaluation for Healthy-Families-Center. For this study the data was collected from the 10 interviewees. The findings were: 1) the major functions of Metro Healthy-Families-Center are the connection between the Central and Basic Center of Healthy Families, support for the Basic Center. 2) the evaluation for Metro and Basic Center is referred as the function of Central Center of Healthy Families. 3) the evaluation-support function of Metro Healthy-Families Center is emphasized. To the further related studies the development of programs corresponding to the functions is suggested.

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A TURÁN-TYPE INEQUALITY FOR ENTIRE FUNCTIONS OF EXPONENTIAL TYPE

  • Shah, Wali Mohammad;Singh, Sooraj
    • Korean Journal of Mathematics
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    • 제30권2호
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    • pp.199-203
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    • 2022
  • Let f(z) be an entire function of exponential type τ such that ║f║ = 1. Also suppose, in addition, that f(z) ≠ 0 for ℑz > 0 and that $h_f(\frac{\pi}{2})=0$. Then, it was proved by Gardner and Govil [Proc. Amer. Math. Soc., 123(1995), 2757-2761] that for y = ℑz ≤ 0 $${\parallel}D_{\zeta}[f]{\parallel}{\leq}\frac{\tau}{2}({\mid}{\zeta}{\mid}+1)$$, where Dζ[f] is referred to as polar derivative of entire function f(z) with respect to ζ. In this paper, we prove an inequality in the opposite direction and thereby obtain some known inequalities concerning polynomials and entire functions of exponential type.

Some Generating Relations of Extended Mittag-Leffler Functions

  • Khan, Nabiullah;Ghayasuddin, Mohd;Shadab, Mohd
    • Kyungpook Mathematical Journal
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    • 제59권2호
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    • pp.325-333
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    • 2019
  • Motivated by the results on generating functions investigated by H. Exton and many other authors, we derive certain (presumably) new generating functions for generalized Mittag-Leffler-type functions. Specifically, we introduce a new class of generating relations (which are partly bilateral and partly unilateral) involving the generalized Mittag-Leffler function. Also we present some special cases of our main result.

국립도서관기능론에 관한 연구 (A study on the theories of national library functions)

  • 오동근
    • 한국도서관정보학회지
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    • 제26권
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    • pp.57-92
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    • 1997
  • This study investigates the national library functions through a study on the theories of their generally accepted functions and based on the results, suggests an idea for the improvements of the functions of the National Library of Korea, the national library of Korea. This study categorizes 22 major functions identified through the analysis on the theories into 4 categories as follows: 1. Functions related to collect and conserve the central collections 2. Functions related to bibliographic control 3. Functions related to the representative role of the nation's libraries, nationally and internationally 4. Functions related to centralized technical and reader services And based on the analysis of the operations of the National Library of Korea. And it is desirable to validate and decide the priority among the functions based on the systematic and through analysis on the operations of the Library and other related libraries.

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Evolution, Transformation, and Representation in Buddhist Architecture - The Square Shrines of Buddhist Monasteries in Central Asia after the Fourth Century

  • Kim, Young-Jae;Han, Dong-Soo
    • Architectural research
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    • 제13권4호
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    • pp.31-42
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    • 2011
  • This study notices that all religions in Central Asia from the fourth century through seventh century C.E. provided considerable hands in keeping a uniform unity through a process of assimilation, although art and architecture were greatly stimulated by the creative genius of the many people. The study thus intends to argue that the common ideas of rituals and primitive forms of religious shrines lead the square-based layout of Buddhist shrines the unity and universality in the architectural products of particular regions or epochs: i.e. the "square-based plan" in Buddhist temples of Central Asia was a significant prototype in the synthesis with pre-Buddhist architectural models and Buddhist universal ideas. Thus, this thesis notes that they did not lose the universal principles of the Buddhist shrine plans due to ritual functions, and even there have been never differences from pre-Buddhist building models remarked by the periods and the venues in which they were produced, although there had been continuous evolutions and adaptive transformations in the local tastes of religious architecture. Accordingly, this study discusses how such plans in Buddhist architecture had been consistently produced within that regional style also representative of the local idioms of architecture, and how they were adopted in the sites, founded on the composition of ritual functions. The foreign architectural cultures were selectively chosen getting along with local building types of each site according to each taste for architecture as a result.

Central Control over Distributed Service Function Path

  • Li, Dan;Lan, Julong;Hu, Yuxiang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제14권2호
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    • pp.577-594
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    • 2020
  • Service Function Chaining (SFC) supports services through linking an ordered list of functions. There may be multiple instances of the same function, which provides a challenge to select available instances for all the functions in an SFC and generate a specific Service Function Path (SFP). Aiming to solve the problem of SFP selection, we propose an architecture consisting of distributed SFP algorithm and central control mechanism. Nodes generate distributed routings based on the first function and destination node in each service request. Controller supervises all of the distributed routing tables and modifies paths as required. The architecture is scalable, robust and quickly reacts to failures because of distributed routings. Besides, it enables centralized and direct control of the forwarding behavior with the help of central control mechanism. Simulation results show that distributed routing tables can generate efficient SFP and the average cost is acceptable. Compared with other algorithms, our design has a good performance on average cost of paths and load balancing, and the response delay to service requests is much lower.

중심합성법에 의한 구조최적화에서 회귀함수변화의 영향 (Effect of Various Regression Functions on Structural Optimizations Using the Central Composite Method)

  • 박정선;전용성;임종빈
    • 한국항공우주학회지
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    • 제33권1호
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    • pp.26-32
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    • 2005
  • 본 연구에서는 반응표면법에 다항함수, 지수함수, 로그함수등을 적용한 다양한 회귀함수를 이용하여 최적화를 수행하였다. 이를 검증하기 위해 트러스 구조와 하니콤 복합재 플랫폼에 대하여 응력 및 고유진동수를 고려하여 최적설계를 수행하였다. 근사함수를 효과적이고 용이하게 하는 방법을 실험계획법이라 하는데 중심합성법, 요인설계법, 회전계획법, 심플렉스법 등이 있으며, 본 연구에서는 중심합성법을 이용하여 반응표면을 생성하였다. 이를 위하여 구조해석 코드로 MSC/NASTRAN을 사용하였으며 최적설계 프로그램은 중심합성법을 기반으로 하여 다양한 회귀모델에 의한 반응표면을 적용하여 작성하였다. 또한 이 결과를 기존의 도함수를 이용한 최적화 기법이나 유전자알고리즘을 이용한 최적화 결과와 비교하여 반응표면법의 설계상의 장점 및 반응표면 생성 시 다양한 회귀모델에의 사용에 대한 신뢰성을 확인하였다.