• Title/Summary/Keyword: Central functions

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The Role of a Neurovascular Signaling Pathway Involving Hypoxia-Inducible Factor and Notch in the Function of the Central Nervous System

  • Kim, Seunghee;Lee, Minjae;Choi, Yoon Kyung
    • Biomolecules & Therapeutics
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    • v.28 no.1
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    • pp.45-57
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    • 2020
  • In the neurovascular unit, the neuronal and vascular systems communicate with each other. O2 and nutrients, reaching endothelial cells (ECs) through the blood stream, spread into neighboring cells, such as neural stem cells, and neurons. The proper function of neural circuits in adults requires sufficient O2 and glucose for their metabolic demands through angiogenesis. In a central nervous system (CNS) injury, such as glioma, Parkinson's disease, and Alzheimer's disease, damaged ECs can contribute to tissue hypoxia and to the consequent disruption of neuronal functions and accelerated neurodegeneration. This review discusses the current evidence regarding the contribution of oxygen deprivation to CNS injury, with an emphasis on hypoxia-inducible factor (HIF)-mediated pathways and Notch signaling. Additionally, it focuses on adult neurological functions and angiogenesis, as well as pathological conditions in the CNS. Furthermore, the functional interplay between HIFs and Notch is demonstrated in pathophysiological conditions.

Point Spread Function of Optical Systems Apodized by Semicircular Array of 2D Aperture Functions with Asymmetric Apodization

  • Reddy, Andra Naresh Kumar;Sagar, Dasari Karuna
    • Journal of information and communication convergence engineering
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    • v.12 no.2
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    • pp.83-88
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    • 2014
  • The simultaneous suppression of sidelobes and the sharpening of the central peak in the process of diffraction pattern detection based on asymmetric apodization have been investigated. Asymmetric apodization is applied to a semicircular array of two-dimensional (2D) aperture functions, which is a series of 'coded-phase arrays of semicircular rings randomly distributed over the central circular region of a pupil function' and is similar to that used in the field of diffractive optics. The point spread function (PSF) of an imaging system with asymmetric apodization of the discrete type has been found to possess a good side with suppressed sidelobes, whereas its bad side contains enhanced sidelobes. Further, the diffracted field characteristics are obtained in the presence of these aperture functions. Asymmetric apodization is helpful in improving the performance of the optical gratings or 2D arrays used in real-time imaging techniques.

The Study on the functions of Metro Healthy-Families-Center and of the Evaluation for Healthy-families-Center (광역 건강가정지원센터의 기능 및 건강가정지원센터 평가 기능에 대한 연구)

  • Song, Hye-Rim;Rah, Hwee-Mun
    • Journal of Family Resource Management and Policy Review
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    • v.13 no.3
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    • pp.1-16
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    • 2009
  • The purpose of this study were to establish the concrete function of Metro Healthy-Families-Center and to find out the function of evaluation for Healthy-Families-Center. For this study the data was collected from the 10 interviewees. The findings were: 1) the major functions of Metro Healthy-Families-Center are the connection between the Central and Basic Center of Healthy Families, support for the Basic Center. 2) the evaluation for Metro and Basic Center is referred as the function of Central Center of Healthy Families. 3) the evaluation-support function of Metro Healthy-Families Center is emphasized. To the further related studies the development of programs corresponding to the functions is suggested.

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A TURÁN-TYPE INEQUALITY FOR ENTIRE FUNCTIONS OF EXPONENTIAL TYPE

  • Shah, Wali Mohammad;Singh, Sooraj
    • Korean Journal of Mathematics
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    • v.30 no.2
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    • pp.199-203
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    • 2022
  • Let f(z) be an entire function of exponential type τ such that ║f║ = 1. Also suppose, in addition, that f(z) ≠ 0 for ℑz > 0 and that $h_f(\frac{\pi}{2})=0$. Then, it was proved by Gardner and Govil [Proc. Amer. Math. Soc., 123(1995), 2757-2761] that for y = ℑz ≤ 0 $${\parallel}D_{\zeta}[f]{\parallel}{\leq}\frac{\tau}{2}({\mid}{\zeta}{\mid}+1)$$, where Dζ[f] is referred to as polar derivative of entire function f(z) with respect to ζ. In this paper, we prove an inequality in the opposite direction and thereby obtain some known inequalities concerning polynomials and entire functions of exponential type.

Some Generating Relations of Extended Mittag-Leffler Functions

  • Khan, Nabiullah;Ghayasuddin, Mohd;Shadab, Mohd
    • Kyungpook Mathematical Journal
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    • v.59 no.2
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    • pp.325-333
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    • 2019
  • Motivated by the results on generating functions investigated by H. Exton and many other authors, we derive certain (presumably) new generating functions for generalized Mittag-Leffler-type functions. Specifically, we introduce a new class of generating relations (which are partly bilateral and partly unilateral) involving the generalized Mittag-Leffler function. Also we present some special cases of our main result.

A study on the theories of national library functions (국립도서관기능론에 관한 연구)

  • 오동근
    • Journal of Korean Library and Information Science Society
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    • v.26
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    • pp.57-92
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    • 1997
  • This study investigates the national library functions through a study on the theories of their generally accepted functions and based on the results, suggests an idea for the improvements of the functions of the National Library of Korea, the national library of Korea. This study categorizes 22 major functions identified through the analysis on the theories into 4 categories as follows: 1. Functions related to collect and conserve the central collections 2. Functions related to bibliographic control 3. Functions related to the representative role of the nation's libraries, nationally and internationally 4. Functions related to centralized technical and reader services And based on the analysis of the operations of the National Library of Korea. And it is desirable to validate and decide the priority among the functions based on the systematic and through analysis on the operations of the Library and other related libraries.

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Evolution, Transformation, and Representation in Buddhist Architecture - The Square Shrines of Buddhist Monasteries in Central Asia after the Fourth Century

  • Kim, Young-Jae;Han, Dong-Soo
    • Architectural research
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    • v.13 no.4
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    • pp.31-42
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    • 2011
  • This study notices that all religions in Central Asia from the fourth century through seventh century C.E. provided considerable hands in keeping a uniform unity through a process of assimilation, although art and architecture were greatly stimulated by the creative genius of the many people. The study thus intends to argue that the common ideas of rituals and primitive forms of religious shrines lead the square-based layout of Buddhist shrines the unity and universality in the architectural products of particular regions or epochs: i.e. the "square-based plan" in Buddhist temples of Central Asia was a significant prototype in the synthesis with pre-Buddhist architectural models and Buddhist universal ideas. Thus, this thesis notes that they did not lose the universal principles of the Buddhist shrine plans due to ritual functions, and even there have been never differences from pre-Buddhist building models remarked by the periods and the venues in which they were produced, although there had been continuous evolutions and adaptive transformations in the local tastes of religious architecture. Accordingly, this study discusses how such plans in Buddhist architecture had been consistently produced within that regional style also representative of the local idioms of architecture, and how they were adopted in the sites, founded on the composition of ritual functions. The foreign architectural cultures were selectively chosen getting along with local building types of each site according to each taste for architecture as a result.

Central Control over Distributed Service Function Path

  • Li, Dan;Lan, Julong;Hu, Yuxiang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.14 no.2
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    • pp.577-594
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    • 2020
  • Service Function Chaining (SFC) supports services through linking an ordered list of functions. There may be multiple instances of the same function, which provides a challenge to select available instances for all the functions in an SFC and generate a specific Service Function Path (SFP). Aiming to solve the problem of SFP selection, we propose an architecture consisting of distributed SFP algorithm and central control mechanism. Nodes generate distributed routings based on the first function and destination node in each service request. Controller supervises all of the distributed routing tables and modifies paths as required. The architecture is scalable, robust and quickly reacts to failures because of distributed routings. Besides, it enables centralized and direct control of the forwarding behavior with the help of central control mechanism. Simulation results show that distributed routing tables can generate efficient SFP and the average cost is acceptable. Compared with other algorithms, our design has a good performance on average cost of paths and load balancing, and the response delay to service requests is much lower.

SLICE REGULAR BESOV SPACES OF HYPERHOLOMORPHIC FUNCTIONS AND COMPOSITION OPERATORS

  • Kumar, Sanjay;Manzoor, Khalid
    • Communications of the Korean Mathematical Society
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    • v.36 no.4
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    • pp.651-669
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    • 2021
  • In this paper, we investigate some basic results on the slice regular Besov spaces of hyperholomorphic functions on the unit ball 𝔹. We also characterize the boundedness, compactness and find the essential norm estimates for composition operators between these spaces.

Effect of Various Regression Functions on Structural Optimizations Using the Central Composite Method (중심합성법에 의한 구조최적화에서 회귀함수변화의 영향)

  • Park, Jung-Sun;Jeon, Yong-Sung;Im, Jong-Bin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.1
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    • pp.26-32
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    • 2005
  • In this paper, the effect of various regression models is investigated on structural optimization using the central composite method. Three bar truss and the upper platform of a satellite are optimized using various regression models that are polynomial, exponential and log functions. Response surface method is non-gradient, semi-global, discrete and fast converging in optimization problem. Sampling points are extracted by the design of experiments using the central composite method. Response surface is generated using the various regression functions. Structural analysis for calculating constraints is executed to find static and dynamic responses. From this study, it is verified that the response surface method has advantage in optimum value and computation time in comparison to other optimization methods.