• Journal of Life Science
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• v.34 no.3
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• pp.179-190
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• 2024

Cannabis sativa is a plant widely cultivated worldwide and has been used as a material for food, medicine, building materials and cosmetics. In this study, we assessed the functional effects of C. sativa stem and root extracts using network pharmacology and confirmed their novel functions. The components in stem and root ethanol extracts were identified by gas chromatography-mass spectrometry analysis, and networks between the components and proteins were constructed using the STICHI database. Functional annotation of the proteins was performed using the KEGG pathway. The effects of the extracts were confirmed in lysophosphatidylcholine-induced THP-1 cells using real-time PCR. A total of 21 and 32 components were identified in stem and root extracts, respectively, and 147 and 184 proteins were linked to stem and root components, respectively. KEGG pathway analysis showed that 69 pathways, including the MAPK signaling pathway, were commonly affected by the extracts. Further investigation using pathway networks revealed that terpenoid backbone biosynthesis was likely affected by the extracts, and the expression of the MVK and MVD genes, key proteins in terpenoid backbone biosynthesis, was decreased in LPC-induced THP-1 cells. Therefore, this study determined the diverse function of C. sativa extracts, providing information for predicting and researching the effects of C. sativa.

• Journal of Korean Society of Steel Construction
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• v.22 no.5
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• pp.487-496
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• 2010

The structural damping ratios for seismic design of nuclear power plant structures are specified in Regulatory guide 1.61 of the United States NRC for RC structures of 4%(OBE) and 7%(SSE), and for steel structures of 3%(OBE) and 4%(SSE), but not for steel-plate concrete (SC) structures that have been developed recently. The objective of this study is to investigate the damping ratios of SC structures by identifying the relative differences in the damping ratios between RC and SC structures. An experimental study was performed on four specimens, RC-S, RC-M, SC-S and SC-M, where S stands for shear-governed and M for moment-governed. The conducted method was free vibration testing by rupturing a brittle steel plate that linked the actuator and the mass center. The test results were analyzed to determine fundamental frequencies and damping ratios at various load levels. By examining the relative differences in damping ratios of four specimens, it is proposed for SC structures to use the same damping ratio of 4% as RC one at OBE, but 1% less damping ratio than RC one resulting in 6% at SSE.

• Journal of the Korea Fashion and Costume Design Association
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• v.18 no.2
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• pp.15-33
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• 2016

Women in their 30s and 40s, who are at the center of "ageless" and "down-aging" consumer trends, are likely to encounter problems with fitting and size conformity when they wear casual clothes targeting women in their 20s. Hence, differences in upper body sizes and body types between women in their 20s and women in their 30s and 40s were analyzed. The data for this study was from the 6th Size Korea survey of body measurements of 1,675 female adults in their 20s-40s. SPSS 21.0 for Windows was used for analysis of the collected data. To examine differences in average upper body size between women in their 20s and women in their 30s and 40s, descriptive statistics and independent sample t-tests were conducted. Factor and cluster analyses were used to classify body types by age groups. Comparing direct measurement items showed that women in their 20s tend to have higher average values for most height-related items-including body height-and lower average values for circumference, thickness, and width than women in their 30s and 40s. Factors in determining the upper body shapes of women in their 20s to 40s were narrowed to five; through a cluster analysis, upper body shapes of women were classified into three body types as follows. Type 1 women are shorter and thinner with small frames; Type 2 women have the highest vertical values for their upper bodies and average values for obesity-related categories of circumference, thickness, and width. Type 3 women are the shortest and has the highest body mass index (BMI), verifiable as obese. By analyzing differences in body type distribution according to age groups, it was found that more than 90% of women in their 20s belong to Types 1 and 2. On the other hand, most women in their 30s and 40s are identified as Type 3.

• The Korean Journal of Air & Space Law and Policy
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• v.30 no.1
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• pp.303-325
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• 2015

The latest slogan put forth by the international space community is the safety, security, and sustainability of outer space activities. The security of outer space activities, in particular, would be defined as the secure state from space-based threats. The latter comprises passive threats (such as collision with other satellites and space debris) and aggressive threats (such as electromagnetic interference, arms race on the earth or in outer space, and military attacks). Has outer space been used for military purposes in practice? If so, does international law regulate the military space activities it? The use of outer space for military purposes is referred to as space militarization and space weaponisation. Satellites has been used in Gulf War, Kosovo War, and Afghan War, recently, and research and development on space weapons are under way. Since only the placement of weapons of mass destruction on orbit around the earth is prohibited in accordance with 1967 Outer Space Treaty, it may be asked whether other weapons may be placed on orbit. It will be necessary to analyze the stance of on the above question, by studying UN space-related treaties including UN Charter. New international space norms represented by PPWT, ICoC, and UN GGE Report are at the center of progressive development of international law. In conclusion, the author will signpost the various points on international norms to be codified on the use of outer space for military purposes.

• Journal of the Society of Disaster Information
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• v.16 no.2
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• pp.267-275
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• 2020

Purpose: In this study, GPR exploration equipment, spray vehicles and flow meters, core drill, borehole image processing system(BIPS), 3D cavity imagery equipment, and cavity formatting equipment were used to identify this cavity growth process. Method: A certain amount of water was injected in proportion to the mass of the cavity, and the cavity was observed to expand as the injected water was drained out. The cavity rating change was evaluated by quantitatively evaluating the expansion factors and the speed of growth. Results: According to the results of examining the volume change through injection time - injection flow rate - volume increase for the four experimenters, the volume increase decreased as the injection time increased, and there was no further increase in volume if injected for one hour or so. Conclusion: In addition, the injection test analyzed the volumetric variation to determine whether the cause of the cavity occurrence was the effect of the underground burial in the vicinity of the cavity. Therefore, it was found that the cavity expansion is caused by the repetition of the relaxation soil collapse due to the groundwater flow and the loss of the collapsed soil below the cavity.

• Journal of Korea Water Resources Association
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• v.39 no.9 s.170
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• pp.779-786
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• 2006

In this study, we propose a new method that utilizes rainfall data in and out of a basin, which is greater than 25.4mm for point rainfall or 12.7mm for areal mean rainfall respectively. From our analysis, most frequent quartile for point and areal mean rainfall were found to be the same in general for various rainfall duration intervals. From an evaluation of design rainfall per each rainfall duration distributed in time by the MOCT(Ministry of Construction and Transportation) version of Huff's method and this study, peak rainfall intensity by this study was found to be greater than the one by MOCT, but there were no consistent increase or decrease of this difference with rainfall durations. Using the distributed design rainfall per each duration by MOCT and this study, corresponding flood inflow hydrographs were simulated and compared each other. Contrary to the case of peak rainfall intensity, difference in peak flow by both methods per each rainfall duration started to increase from about 12-hr duration. Especially, the difference in peak flow was significant when critical rainfall duration was considered, and this trend was similar for peak flows of other rainfall durations. Therefore, the method proposed in this study is thought to be the effective procedure for the construction of dimensionless cumulative rainfall curve that is representative of a basin while considering time distribution characteristics for different rainfall durations.

• Korean journal of applied entomology
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• v.50 no.1
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• pp.55-63
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• 2011

This study was conducted to develop an artificial diet for the mugwort looper, Ascotis selenaria (Lepidoptera: Geometridae), which is an insect pest to leaves of citrus (Citrus unshiu). Corn and soybean powder were selected as main nutrient sources for larvae of A. selenaria after several diets consisted of wheat germ, corn, kidney bean and/or soybean were tested for larval development and survival. A higher amount of the main nutrients in the diet increased the larval survivorship. Addition of yeast and cholesterol in diet increased the larval survivorship. Finally the composition of diet was decided as followings; corn 100 g, soybean 100 g agar 25 g, Brewers' yeast 30 g, cholesterol 0.5 g, Vanderzant vitamin mixture 2 g, Wesson's salt mixture 2 g, sorbic acid 2 g, ascorbic acid 2 g, and methyl-4-hydroxybenzoate 2.5 g, and distilled water 1 liter. Development periods of larvae and pupae, survival rate and fecundity of A. selenaria reared on the diet were not significantly different with those on the host plant, citrus leaves. Larvae of early instars were reared in a group, while larvae of later instars (5-6th) were reared individually. Adult mating was conducted in a plastic cage and an oilpaper covered with a gauze was provided as an oviposition site.

• Applied Biological Chemistry
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• v.39 no.1
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• pp.1-8
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• 1996

A one-stage, continuous-flow bioreactor with both immobilized and suspended cells was used to investigate the roles of lipid supplements in ethanol production by Saccharomyces cerevisiae. The reactor performance and the level of alcohol dehydrogenase(ADH) activities of the suspended cells, grown under various conditions, were measured. When ergosterol and/or oleic acid were added with surfactants to the yeast culture grown under non-aerated conditions, remarkable increases in ethanol production and cell growth was achieved, but specific ADH activities were not affected. Especially, no difference of specific ADH activities of the suspended cells grown under aerated and non-aerated condition was observed. The addition of the surfactant as a supplement also resulted in significant increases in ethanol production, cell growth, and specific ADH activity. When ergosterol and oleic acid were added to the yeast culture exposed to higher ethanol concentration($>40\;g/{\ell}$) level, ethanol production, cell growth, and specific ADH activity were increased, but the addition of surfactant was as effective as at lower ethanol concentration level. The results indicated that lipid supplements were more effective at higher ethanol concentration level than at lower ethanol concentration level during ethanol production. ADH isozyme patterns of the yeast cultures grown under various conditions on starch gel electrophoresis showed only one major band, probably ADH I. The migrating distance of the major isozyme, however, varied slightly according to the culture conditions of the cells. No apparent correlation was found between specific ADH activity and amount of ethanol produced. Cell mass was more important factor for ethanol production than specific ADH activity of the cells.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.223-229
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• 2020

Biodiesel produced using microorganisms, which are recognized as the third-generation biomass, is among the various known renewable energy sources that can replace fossil fuels used in conventional transportation. Scenedesmus obliquus has been identified as an excellent species for biodiesel production, as it grows faster and can accumulate up to 40-50 percent of the dry cell weight. Enhancing production using S. obliquus requires measuring the cell mass for controlling the cultivation process. In the current study, S. obliquus was cultured for 75 days, and growth changes of the microalgae were measured by absorbance, microscopic imaging, and Raman spectroscopy. Between days 60 to 75 of culture, the change in absorbance was observed to be less than 3%, whereas the number of microalgae observed microscopically was more than three times higher. Moreover, the Raman spectroscopy results showed three strong peak values of β-carotene at 997 cm^-1, 1148 cm^-1, and 1515 cm^-1, with peak values of β-carotene showing greater than 3-fold increase during the culture period. Therefore, we predict that application of Raman spectroscopy will help in identifying the growth elements and growth degree in microalgae culture during increased biomass production.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.7 no.2
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• pp.167-175
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• 2012

This paper study about how government start-up promotion policies have strongly impacts on business startup pattern and its performance. In Korea, the economic crisis of the late 1990s, the recession continues to stumble, and corporate restructuring occurs, let a small mass of unemployed, the Soho establishment 'Sojabon' started brewing two booms. Small business owners and their economic contribution to this portion of the axis with respect to support economic growth theory, on the basis that you need to install the Support Center for more small business owners and small business owners and social atmosphere, changing the term action to promote the establishment and growth of employment opportunities through by creating regional, has been promoting the balanced development of between business. This scheme focus on examining the types and characteristics of the government support schemes with respect to start-process business plan completion, financing capability, utilizing level of experts, location advantage, level of industry differentiation. Results of this study shows how significantly entrepreneurship influence on business startup pattern determining successful performance of business startup and let potential entrepreneur utilize it as to proceed business planning and establishing strategies.