• Title/Summary/Keyword: Cell-to-Cell Deviation

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Adaptive Control of Peak Current Mode Controlled Boost Converter Supplied by Fuel Cell

  • Bjazic, Toni;Ban, Zeljko;Peric, Nedjeljko
    • Journal of Power Electronics
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    • v.13 no.1
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    • pp.122-138
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    • 2013
  • Adaptive control of a peak current mode controlled (PCM) boost converter supplied by a PEM fuel cell is described in this paper. The adaptive controller with reference model and signal adaptation is developed in order to compensate the deviation of the response during the change of the operating point. The procedure for determining the adaptive algorithm's weighting coefficients, based on a combination of the pole-zero placement method and an optimization method is proposed. After applying the proposed procedure, the optimal adaptive algorithm's weighting coefficients can be determined in just a few iterations, without the use of a computer, thus greatly facilitating the application of the algorithm in real systems. Simulation and experimental results show that the dynamic behavior of a highly nonlinear control system with a fuel cell and a PCM boost converter, can fairly accurately be described by the dynamic behavior of the reference model, i.e., a linear system with constant parameters.

Analytical Research to Determine the effects of the Components of ONGABO on the Viability of HepG2 Cancer Cells by Using the Sovereign, Minister, Assistant and Courier Principle (君臣佐使論)

  • Shin, Jeong-Hun;Jun, Seung-Lyul;Hwang, Sung-Yeoun;Ahn, Seong-Hun
    • Journal of Pharmacopuncture
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    • v.15 no.4
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    • pp.42-51
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    • 2012
  • Objectives: This study used the basic principle of Oriental medicine, the sovereign, minister, assistant and courier principle (君臣佐使論) to investigate the effects of the component of ONGABO, which is composed of Ginseng Radix (Red Ginseng), Angelica Gigantis Radix, Schisandrae Fructus, Cuscuta Semen and Curcumae tuber on the viability of HepG2 cells. Methods: Single and mixed extracts of the component of ONGABO were prepared by lypohilizing powder of Red Ginseng (6-year root from Kanghwa), Angelica Gigantis Radix, Schisandrae Fructus, Cuscuta Semen, Curcumae Tuber (from Omniherb Co., Ltd., Korea) at the laboratory of herbal medicine in Woosuk University and were eluted after being macerated with 100% ethanol for three days. The cell viability of HepG2 was determined by using an absorptiometric analysis with PrestoBlue (Invitrogen) reagent after the plate had been incubated for 48 hours. All of the experiments were repeated three times to obtain the average value and standard deviation. The statistical analysis was done and the correlation factor was obtained by using Microsoft Office Excel 2007 and Origin 6.0 software. Results: Although Ginseng Radix (Red Ginseng) and Schisandrae Fructus did not enhance the viability of HepG2 cells, they were shown to provide protection of those cells. On the other hand, Angelica Gigantis Radix decreased the viability of HepG2 cells significantly, Cuscuta Semen and Curcumae Tuber had a small or no effect on the viability of HepG2 cells. Conclusions: In the sovereign, minister, assistant and courier principle (君臣佐使論), Ginseng Radix (Red Ginseng) corresponds to the sovereign component because it provides cell protection effects, Angelica Gigantis Radix corresponds to minister medicinal because it kills cells, Schisandrae Fructus corresponds to the assistant medicinal to help red ginseng having cell protect effects. Cuscuta Semen and Curcumae Tuber correspond to the courier medicinal having no effect in cell viability in HepG2. We hope this study provides motivation for advanced research on the sovereign, minister, assistant and courier principle.

FORTRAN Program "PHYLS" for the Geometrical Prediction of the Structures of 1M and $2M_1$ 2:1 Phyllosilicates Having Space Groups C2/m, C2, and C2/c (공간군 C2/m, C2, 및 C2/c를 갖는 1M 및 $2M_1$ 2:1 층상 규산염 광물 구조의 기하학적 예측을 위한 포트란 프로그램 "PHYLS")

  • ;M. Slaughter
    • Journal of the Mineralogical Society of Korea
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    • v.11 no.1
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    • pp.45-67
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    • 1998
  • FORTRAN program PHYLS was developed to model the structures of 2:1 1M and 2M1 phyllosilicates on the basis of geometrical analyses. Input to PHYLS requires the chemical composition and d(001) spacing of the mineral. The output from PHYLS consists of the coordinates of the crystallographically independent sites in the unit cell, and such structural parameters as the cell dimensions, interaxial angle, cell volume, interatomic distances, and deformation angles of the polyhedra. PHYLS can generate these structural details according to the user's choice of space group and cation configuration. User can choose one of such space groups as C2/m, C2,and C2/c and such cation configurations as random and ordered tetrachedral/octahedral cation configurations. PHYLS simulated the structures of dioctahedral and trioctahedral phyllosilicates having random tetrahedral cation configuration fairly close to the reported experimentally determined structures. In contrast, the simulated structures for ordered tetrahedral cation configurations showed greater deviation from the experimentally determined structures than those for random configurations. However, if the cations were partially ordered and the sizes of the tetrahedra became similar, the simulated PHYLS may be helpful in various investigations on the relationships between structures and physicochemical properties of the phyllosilicates.

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Helper T Cell Polarizing Through Dendritic Cells (수지상세포를 통한 조력 T세포의 분화 - 알레르기 질환을 중심으로 -)

  • Han, Manyong
    • Clinical and Experimental Pediatrics
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    • v.48 no.1
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    • pp.6-12
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    • 2005
  • In the last few years, a spectrum of dendritic cells(DCs), including toll like receptors(TLRs), might play a critical role in regulating allergy and asthma. DC plays a central role in initiating immune responses, linking innate and adaptive responses to pathogen. Human peripheral blood has three non-overlapping dendritic subset that expressed various 11 TLRs. These dendritic subsets and TLR contribute significant polarizing influences on T helper differentiation, but how this comes about is less clear. A better understanding of DC immunobiology may lead to the comprehension of allergy pathophysiology to prevent early stage allergic march.

Compression and Dewatering of Chinese Cabbage (배추의 압축탈수특성에 관한 연구)

  • Kim, Y.J.;Lee, D.H.;Lee, Y.B.
    • Journal of Biosystems Engineering
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    • v.19 no.1
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    • pp.3-8
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    • 1994
  • An experiment on the expression and dewatering of chinese cabbage was conducted in order to investigate its dewatering behavior. Chopped cabbage was packed into cylinder and pressed by piston upto the predetermined pressure on Instron-1000. The rates of dewatering were affected domintantly by the applied pressure, but not significantly by the packed amount of cabbage in the cylinder. The pressure effect was increased very abruptly at first, but the increase rate was very low at high pressure greater than 20 MPa, showing great deviation from linear dependence of flow rate on pressure in Darcy's Law. Therefore, water expression from cabbage was not Newtonian flow of water through cell wall. In fact, the squeezed water contained a lot of solid particles, about 3% of solid cabbage particles, showing destruction of cell wall. It appeared that compression and dewatering of vegetable wastes in the low pressure. under 20 MPa, is more desirable for later treatment of the dewater. More researches are needed in order to develop a treatment method for the solid particles in the expressed water before an expeller treatment system can be applied to vegetable wastes.

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Expression Characteristics of Chinese Cabbage

  • Kim, Y.J.;Oh, Y.T.;Lee, D.H.;Lee, Y.B.
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1993.10a
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    • pp.1318-1328
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    • 1993
  • Expression of chinese cabbage was conducted in order to investigate its dewatering behavior. Chipped cabbage was packed into cylinder and pressed by piston up to the predetermined pressure on Instron-1000. The rates of dewatering were affected domintantly by the applied pressure, but not significantly by the packed amount of cabbage in the cylinder. The pressure effect was increased very abruptly at first, but the increase rate was very low at high pressure greater than 20 MPa, showing great deviation from linear dependence of flow rate on pressure in Darcy's Law. Therefore, water expression from cabbage was not Newtonian flow of water through cell wall. In fact, the squeezed water contained a lot of solid particles, showing destruction of cell wall. The content of solid particles in expressed water was only slightly lower than the dry matter content of fresh chinese cabbage, determined by drying oven method.

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Activity Measurement in Liquid Zn-(In, Sn) Alloy Using E.M.F Method (기전력법에 의한 용융 ZR-(In, Sn) 합금의 활동도 측정)

  • Jung Woo-Gwang
    • Korean Journal of Materials Research
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    • v.15 no.1
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    • pp.47-53
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    • 2005
  • The E.M.F. of the galvanic cell with fused salt was measured to determine the activities of zinc at 720-860 K over the entire composition range of liquid Zn-In and Zn-Sn alloys. The cell used was as follows: $$(-)W{\mid}Zn(pure){\mid}Zn^{2+}(KCl-LiCl){\mid}Zn(in\;Zn-In\;or\;Zn-Sn\;alloy){\mid}W(+)$$ The activities of zinc in the alloys showed positive deviation from Raoult's law over the entire composition range. The activity of cadmium and some thermodynamic functions such as Gibbs free energy, enthalpy and entropy were derived from the results by the thermodynamic relationship. The comparison of the results and the literature data was made. The liquid Zn-In and Zn-Sn alloys are found to be close tn the regular solution. The concentration fluctuations in long wavelength limit, $S_{cc}(o)$, in the liquid alloy were calculated from the experimental results.

A Diffuse Large B-Cell Lymphoma in Nasal Sinuses Accompanying with Exophthalmos:A Case Report (안구 돌출을 동반한 비부비동의 미만성 큰 B세포 림프종 1예)

  • Kim, Heui-Ju;Kim, Jin-Young;Yoo, Young-Sam;Cho, Kyoung-Rai
    • Korean Journal of Head & Neck Oncology
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    • v.24 no.1
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    • pp.69-72
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    • 2008
  • Lymphomas of the nasal sinuses are relatively uncommon and represent less than 1% of all head and neck malignancies. Most common symptoms are nasal obstruction, epistaxis, rhinorrhea. We report a case of primary extranodal diffuse large B-cell non-Hodgkin's lymphoma in nasal sinuses accompanying with exophthalmos. A 70-year-old male patient was referred to our hospital with exophthalmos and severe septal deviation. We conducted endoscopic biopsy with septoplasty and biopsy result was diffuse large B-cell lymphoma. He received chemotherapy(R-CHOP) and radiotherapy. At follow-up, he remained free of disease.

Theoretical Analysis of Phase Detector Technique for the Measurement of Cell Membrane Capacitance During Exocytosis (세포외 분비시 막 캐패시턴스를 측정하기 위한 위상감지법(phase detector technique)의 이론적 분석.)

  • Cha, Eun-Jong;Goo, Yong-Sook;Lee, Tae-Soo
    • Progress in Medical Physics
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    • v.3 no.2
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    • pp.43-57
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    • 1992
  • Phase detector techique provides a unique probe to membrane recycling phenomenon by enabling dynamic monitoring of cell membrane capacitance. However, it has inherent errors due to constant changes in measurement environments. The present study analyzed several error sources to develope application criteria of this technique. and the following was found based on a theoretical analysis. The initial phase angle has to be appropriately selected to minimize the error due to perturbation of access and membrane conductances. Excitation frequency is also important to determine the initial phase angle. However. deviation of the phase angle from a predetermined initial value during the measurement period does not affect capacitance estimation to a significant degree. Despite an appropriate initial phase selection an error in scaling factor is expected for a large increase in capacitance during exocytosis. which may be overcome by iteratively correcting the scaling factor over the measurement period. These results will provide a useful guideline in practical application of this technique.

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The Simulation of Myocardium Conduction System using DEVCS and Discrete Time CAM (DEVCS 및 Discrete Time CAM을 이용한 심근 전도 시스템의 시뮬레이션)

  • Kim, K.N.;Nam, G.K.;Son, K.S.;Lee, Y.W.;Jun, K.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.150-155
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    • 1997
  • Modelling and Simulation of the activation process for the myocardium is meaningful to understand special excitation conduction system in the heart and to study cardiac functions. In this paper, we propose two dimensional cellular automata model for the activation process of the myocardium and simulated by means of discrete time and discrete event algorithm. In the model, cells are classified into anatomically similar characteristic parts of heart; SA node, internodal tracks, AV node, His bundle, bundle branch and four layers of the ventricular muscle, each of which has a set of cells with preassigned properties, that is, activation time, refractory duration and conduction time between neighbor cell. Each cell in this model has state variables to represent the state of the cell and has some simple state transition rules to change values of state variables executed by state transition function. Simulation results are as follows. First, simulation of the normal and abnormal activation process for the myocardium has been done with discrete time and discrete event formalism. Next, we show that the simulation results of discrete time and discrete event cell space model is the same. Finally, we compare the simulation time of discrete event myocardium model with discrete time myocardium models and show that the discrete event myocardium model spends much less simulation time than discrete time myocardium model and conclude the discrete event simulation method Is excellent in the simulation time aspect if the interval deviation of event time is large.

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