Dietary powder from Plantaginis ovatae testa was prepared by mechnical milling/grinding of the outer layer of the seed. The crystalline/surface structures of its powder (100 mesh) were examined, and several physical functionalities including, water capacity, oil holding capacity, emulsion/foam properties and physiological functionality such as in-vitro glucose and bile acid retarding effects were also investigated. Water holding capacity(WHC) of psyllium powder was $33.71{\pm}0.10g$ water retained/g solid at room temperature, whileas oil holding capacity(OHC) for soybean or rice bran oil were about 1.80g oil retained/g solid. These values of WHC and OHC were about 5.6 times higher and 2.8 times lower than those of commercial ${\alpha}$-cellulose, respectively. Changes of pH showed a small effect on WHC, but WHC increased with temperature. Emulsion capacity of 2%(w/v) psyllium was about 60% level of 0.5%(w/v) xanthan gum but emulsion stability after incubation of 24 hours showed about 1.4 times improvement of xanthan gum(0.5%,w/v). Also, psylliume(above 2%, w/v) alone had higher foam capacity than that of xanthan(1.1 times) and especially, 1 or 2% addition of psyllium improved the foam stability of protein solution(1% albumin+0.5% $CaCl_2$) by factor of 3.3 and 6.0 times, respectively. The glucose and bile acid retarding effects of psyllium powder were relatively very excellent suggesting the prevention from diabetes and arteriosclerosis. Especially, psyllium showed the 3.7 and 3.3 times higher effect on in-vitro glucose and bile acid retardation than those of commercial ${\alpha}$-cellulose, respectively.
Proceedings of the Korean Geotechical Society Conference
/
2009.09a
/
pp.1001-1010
/
2009
The study that unconfined compression strength of intact rock which is the most important factor to determine the bearing capacity effects discontinuities in rock mass has been carried out actively so far. However, the study which is related to lithological characters such as vesicle which is one of the primary characteristics of Basalt has barely been conducted. On this study, We have analyzed the correlation-ship between vesicle and unconfined compression strength and the effect on the bearing capacity, based on the reviewing on the changes of unconfined compression strength as the amount of vesicle of Basalt. It is impossible to analyze the amount of vesicle of Basalt as measuring unit. So it was analyzed by the ratio of the core sample's surface area and another area that vesicle takes up. Also, unconfined compression strength was calculated by point load test and unconfined compression strength test. The analysis shows that vesicle area ratio and unconfined compression strength have the exponential relationship and vesicle area ration is the factor to determine the bearing capacity of Basalt. It is considered that the reliability of calculating of the bearing capacity of Basalt will be improved as we study the correlation-ship between the vesicle area ratio and rock mass grade hereafter.
A series of centrifuge model tests to investigate the suction pile pullout loading capacity in sand have been performed. The main parameters that affect the pullout loading capacity of a suction pile include the mooring line inclination angle and the padeye position of the suction pile. With respect to the padeye position, the maximum pullout loading capacity is obtained when the padeye position is near 75% of the pile length from the top. The direction of the pile rotation changes when the padeye position reaches somewhere near 50~75% for all mooring line inclination angles. The translation displacement of suction pile to develop the time of maximum pullout loading capacity decreased as the mooring line inclination angle increased. In addition, the vertical displacements of the center of a suction piles for all cases appeared to develop toward the ground surface.
This study was conducted to find out the rational and appropriate design of drilled shaft. In other words, in order to find out the variation of ultimate bearing capacity according to the change in the support layer of drilled shaft, back analysis was performed using the bi-directional pile load test performed on drilled shaft. Based on the back-analyzed data, numerical analysis of the pile head load was performed, and the ultimate bearing capacity in the target ground was evaluated using the Davisson method. As a result of numerical analysis of one case where the end of the pile was seated on the top of the weathered rock layer, and three cases where the end of the pile was embedded at different locations in the weathered soil, it was found that sufficient ultimate bearing capacity was secured in all cases. In other words, the case where the end of the pile is seated on the top of the weathered rock layer, not embedded the weathered rock, and the drilled shaft embedded into the weathered soil also have sufficient bearing capacity, so it can be used as a support layer for drilled shaft.
This study was performed to assess age-related changes in DNA damage and antioxidative capacity in 4, 8, 12, 16, 20, and 24 months old Sprague-Dawley male rats. The following were measured the degree of oxidative DNA damage as indicated by levels of 8-hydroxy-2'-deoxyguanosine (80HdG) in the kidney ; the peroxidized lipid concentrations in the plasma and the liver, as indicated by the levels of thiobarbituric acid reactive substances (TBARS); and the levels of antioxidant enzyme activities in the erythrocytes and the liver. Both body weight (BW) and epididymal fat pad (EFP) weight per BW increased with age until 16 months, then decreased slightly from 20 to 24 months. However, the weights of the liver, kidney and spleen per BW decreased with age. Concentrations of 8-OHdG in the kidney increased with age, only slightly front 4 to 16 months, and then markedly from 16 to 24 months. TBARS concentrations in the plasma and liver were shown to increase with age, being lowest in the 4 month-old group and highest in the 24 month-old group. Superoxide dismutase (SOD) activity in the erythrocytes increased with age Catalase activity in the erythrocytes increased from 4 to 16 months, then decreased from 20 to 24 months. Glutathione peroxidase (GSH-Px) activity in the erythrocytes showed no age-related change. Liver SOD activity decreased with age, particularly from 16 to 20 months, but catalase and GSH-Px activities in the liver showed no significant changes. These results showed that during the normal aging of SD rats, DNA damage in the kidney and TBARS concentrations in the plasma and liver increased with age, particularly after 16 months, and the imbalance of antioxidative enzyme activities in the erythrocytes accelerated with age.
There is a marked increase in geriatric disease, especially liver disease, due to the continuous increase in alcohol and fat consumption. Since the fatty liver, induced by alcohol or fat, is basically from abnormalities in the lipid metabolism, it is possible that fatty acid binding protein(FABP) which is related to the fatty acid metabolism may also be abnormal in these livers. FABP is a small molecular weight protein family present in cytosol in high concentration. It has been proposed as a fatty acid transfer protein and as a binding protein responsible for controlling intracellular free fatty acid concentration. In this research, we have examined the relationship between liver FABP and fatty liver induced by alcohol or high cholesterol diet. Rats were fed one of either semipurified liquid diets; control diet containing 65% carbohydrate, 20% protein, and 15% fat or high cholesterol diet containing 1%(w/w) cholesterol or alcohol diet containing 37% of alcohol instead of carbohydrate. After 5 weeks of feeding period, all rats received commercial chow diet for 5 weeks to examine recovery effect. Liver and blood samples were collected at 0, 1, 3, 5 and 10 weeks to analyze lipid compositions. FABP was purified from liver cytosol and injected to rabbit to obtain antiserum. Liver FABP amount was determined by SDS-PAGE and western blotting methods. Fatty acid binding capacity was determined by binding of 14Cpalmitate with the delipidated liver cytosol. Consumption of alcohol increased serum cholesterol, triglyceride concentration and decreased HDL-cholesterol concentration after 5 weeks. Serum apolipoprotein B concentration increased after 3 weeks and LDL-cholesterol and apolipoprotein A concentration changed after 1 week. Liver cholesterol and triglyceride concentration increased after 3 weeks. Consumption of high cholesterol diet changed liver and serum lipid composition after 3 weeks. Swiching to normal diet for 5 weeks did not normalize most of lipid composition in serum and liver except serum and liver except serum cholesterol, triglyceride and liver cholesterol. Liver cytosol FABP content and the fatty acid binding capacity decreased dramatically after 1 week with alcohol consumption. This results indicate that FABP content changes before the changes before the changes of blood or liver lipid composition, suggesting changes of FABP may cause development of the fatty liver induced by alcohol and can be used as an index of detecting a early development of fatty liver.
Journal of the Korean Society of Fisheries and Ocean Technology
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v.54
no.3
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pp.217-223
/
2018
Overfishing capacity has become a global issue due to over-exploitation of fisheries resources, which result from excessive fishing intensity since the 1980s. In the case of Korea, the fishing effort has been quantified and used as an quantified index of fishing intensity. Fisheries resources of coastal fisheries in the Korean waters of the East Sea tend to decrease productivity due to deterioration in the quality of ecosystem, which result from the excessive overfishing activities according to the development of fishing gear and engine performance of vessels. In order to manage sustainable and reasonable fisheries resources, it is important to understand the fluctuation of biomass and predict the future biomass. Therefore, in this study, we forecasted biomass in the Korean waters of the East Sea for the next two decades (2017~2036) according to the changes in fishing intensity using four fishing effort scenarios; $f_{current}$, $f_{PY}$, $0.5{\times}f_{current}$ and $1.5{\times}f_{current}$. For forecasting biomass in the Korean waters of the East Sea, parameters such as exploitable carrying capacity (ECC), intrinsic rate of natural increase (r) and catchability (q) estimated by maximum entropy (ME) model was utilized and logistic function was used. In addition, coefficient of variation (CV) by the Jackknife re-sampling method was used for estimation of coefficient of variation about exploitable carrying capacity ($CV_{ECC}$). As a result, future biomass can be fluctuated below the $B_{PY}$ level when the current level of fishing effort in 2016 maintains. The results of this study are expected to be utilized as useful data to suggest direction of establishment of fisheries resources management plan for sustainable use of fisheries resources in the future.
Ahammad, Muslah U.;Okamoto, S.;Kawamoto, Yasuhiro;Nakada, T.
Asian-Australasian Journal of Animal Sciences
/
v.24
no.9
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pp.1199-1203
/
2011
The objective of this study was to examine the binding potential of sperm to the epithelium of the sperm storage tubules (SST) in vitro and in vivo to assess the functional maturation of fowl sperm. Sperm from the testis, epididymis, as well as the proximal, middle and distal vas deferens were incubated in vitro with either the uterovaginal junction (UVJ)- or infundibular tissue containing SST at $39^{\circ}C$ for 30 min. Aliquots of sperm were also artificially inseminated into the uteri of hens, and the UVJ and infundibulum were collected 24 h post artificial insemination (AI). After incubation and AI, tissues were washed to remove loosely adhered sperm and subjected to fluorescence staining with 4', 6-diamidino-2-phenylindole, dihydrochloride (DAPI) for counting the number of bound sperm per 0.25 mm2 of surface area. Sperm from the testis, epididymis, and the three segments of the vas deferens exhibited their differential (p<0.05) binding capacity, which increased gradually from the testicular to distal vas deferens sperm under both in vitro and in vivo conditions. Existing similar trend, sperm, regardless of their source had a lesser affinity to bind to the epithelium of the infundibular SST than to the UVJ-SST. These experimental results suggested that fowl sperm may undergo gradual changes in the process of functional maturation, whereby they gain the ability to bind to the epithelium of the SST during their passage through the male reproductive tract (MRT).
This study was performed to investigate the age-related changes of the lipid metabolism and thrombogenic capacity in Sprague-Dawley (SD) rats at the ages of 4, 8, 12, 16, 20 and 24 months old. Total lipid, triglyceride (TG) and total cholesterol in plasma and liver, HDL-cholesterol concentration, and eicosanoid contents in plasma were measured. Lipid peroxides were determined by the levels of thiobarbituric acid reactive substance (TBARS) in LDL fraction. Body weight was increased continuous until 16 months and decreased after 20 months. Epididymal fat pad (EFP) weight was increased continuously until 20 months and decreased at 24 months. Total lipid and TG concentrations in plasma were increased until 20 months and then rapidly decreased at 24 months but plasma cholesterol was increased continuously with aging. HDL-cholesterol level was increased continuously until 12 months, but decreased at 16 months and maintained there after. The TBARS levels in LDL fraction were the highest level at 24 months. Liver total lipid, TG, and total cholesterol concentrations were shown a tendency to increase with aging, and especially TG concentration was increased rapidly from 12 months to 16 months. Plasma thromboxane B$_2$ (TXB$_2$) and 6-keto-prostaglandin F$_1$ (6-keto-PGF$_1$) contents did not change with aging, but the ratio of TXB$_2$/6-keto-PGF$_1$ was increased with aging, especially from 8 to 12 months. These results showed that lipid levels in plasma and liver, TBARS levels in LDL fraction, and TXB$_2$/6-keto-PGF$_1$ ratio were increased with aging.
This study explores the inelastic behavior of systems with flexible base. The use of a single degree of freedom system (ESDOF) with equivalent ductility to represent the response of flexible base systems is discussed. Two different equations to compute equivalent ductility are proposed, one which includes the contribution of rigid body components, and other based on the overstrength of the structure. In order to asses the accuracy of ESDOF approach with the proposed equations, the behavior of a 10-story regular building with reinforced concrete (RC) moment resisting frames is studied. Local and global ductility capacity and demands are used to study the modifications introduced by base flexibility. Three soil types are considered with shear wave velocities of 70, 100 and 250 m/s. Soil-foundation stiffness is included with a set of springs on the base (impedance functions). Capacity curves of the building are computed with pushover analysis. In addition, non linear time history analysis are used to asses the ductility demands. Results show that ductility capacity of the soil-structure system including rigid body components is reduced. Base flexibility does not modify neither yield and maximum base shear. Equivalent ductility estimated with the proposed equations is fits better the results of the numerical model than the one considering elastoplastic behavior. Modification of beams ductility demand due to base flexibility are not constant within the structure. Some elements experience reduced ductility demands while other elements experience increments when flexible base is considered. Soil structure interaction produces changes in the relation between yield strength reduction factor and structure ductility demand. These changes are dependent on the spectral shape and the period of the system with fixed and flexible base.
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