• Restorative Dentistry and Endodontics
• /
• v.27 no.6
• /
• pp.632-643
• /
• 2002

The purpose of this study was two-fold. First was to evaluate whether the molecular sieving model was appropriate for ionic dissociation experiment. Second was to compare the dissociation of calcium and hydroxyl ions from five types of calcium hydroxide pastes (Pure calcium hydroxide paste, DT temporary $dressing^{\circledR},{\;}Metapaste^{\circledR},{\;}Chidopex^{\circledR},{\;}Metapex^{\circledR}$) in three vehicles (aqueous, viscous and oily) and the antibacterial effect. Each calcium hydroxide pastes was placed into 0.65ml tube with cap and then 15% polyacrylamide gel was placed onto calcium hydroxide pastes. After the gel was hardened, the tubes were filled with tridistilled water (pH 7.14) and closed with cap. The tubes were stored in $37^{\circ}C$ 100% incubator The pH reading and the concentration of calcium ions were taken at 1, 4, 7. 10, and 14 days. The brain heart infusion agar plates with S. mutans and A. actinomycetemcomitans were used far antibacterial activity test. Middle of agar plate was filled with the calcium hydroxide pastes. The plates were incubated at $37^{\circ}C$ and observations were made to detect the zones of inhibition. These data were evaluated statistically by use of the analysis of variance and duncan test. The results were as follows. 1. In fresh mixing state, the pH of five types of calcium hydroxide pastes were measured between 12.5 and 12.8. 2. The pH was increased in all five types of calcium hydroxide pastes compared with control group. In 14 days, Pure calcium hydroxide paste (11.45) and DT temporary $dressing^{\circledR}$ (11.33) showed highest pH, followed by $Metapaste^{\circledR}$ (9.49), $Chidopex^{\circledR}$ (8.37) and $Metapex^{\circledR}$ (7.59) 3. Calcium was higher in all five types of calcium hydroxide pastes compared with control group. In 14 days, Pure calcium hydroxide paste (137.29 mg%) and DT temporary $dressing^{\circledR}$ (124.6 mg%) showed highest value, followed by $Metapaste^{\circledR}$ (116.74 mg%), $Chidopex^{\circledR}$ (111.84 mg%) and $Metapex^{\circledR}$ (60.22 mg%). 4. The zones of bacterial inhibition were seen around all five types of calcium hydroxide pastes. $Chidopex^{\circledR}{\;}and{\;}Metapex^{\circledR}$ groups which include iodoform were observed significantly larger zone of inhibition in A. actinomycetemcomitans compared with the other calcium hydroxide groups (p<0.05) However, $Metapex^{\circledR}$ showed the least antibacterial effect on S. mutans compared with other groups (p<0.05). The molecular sieving model was found to be acceptable in dissociation experiment of hydroxyl and calcium ions when compared with the previous tooth model study. But this model was not appropriate for the antibacterial test.

• Journal of Life Science
• /
• v.31 no.1
• /
• pp.83-89
• /
• 2021

Uu-ilys, an i-type lysozyme from spoon worm (Urechis unicinctus), is an innate immune factor that plays an important role in the defense against pathogens. It also possesses non-enzymatic antibacterial activity. Thus, there is a possibility to develop an antimicrobial model peptide from Uu-ilys. In this study, we report the design, production, and antibacterial activity of an Uu-ilys analog that exhibits antibacterial activity. The Uu-ilys structure was fragmented according to its secondary structures to predict the regions with antimicrobial activity using antimicrobial peptide (AMP) prediction tools from different AMP databases. A peptide containing the C-terminal fragment was predicted to exert antimicrobial activity. The chosen fragment was designated as an Uu-ilys analog containing the C-terminal fragment, Uu-ilys-CF. To examine the possibility of developing an AMP using the sequence of Uu-ilys-CF, recombinant fusion protein (TrxA-Uu-ilys-CF) was produced in an expression system that was heterologous. The produced fusion protein was cleaved after methionine leaving Uu-ilys-CF free from the fusion protein. This was then isolated through high performance liquid chromatography and reverse phase column, CapCell-Pak C18. The antibacterial activity of Uu-ilys-CF against different microbial strains (four gram-positive, six gram-negative, and one fungal strain) were assessed through the ultrasensitive radial diffusion assay (URDA). Among the bacterial strains tested, Salmonella enterica was the most susceptible. While the fungal strain tested was not susceptible to Uu-ilys-CF, broad spectrum antibacterial activity was observed.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.47 no.4
• /
• pp.297-304
• /
• 2021

In this study, we prepared a pigmented skin model, KeraSkin-M^TM for the in vitro evaluation of whitening agents. For the purpose of complementing the existing mono-layer cell culture testing method, KeraSkin-M^TM was produced through the co-culture of human skin-derived keratinocytes and melanocytes. The efficacy of four well-known whitening agents (arbutin, ascorbic acid, kojic acid, niacinamide) was evaluated in KeraSkin-M^TM in order to assess its usefulness in assessing whitening efficacy. As a result, it was possible to observe additional details such as the distribution of melanin granules and melanin capping in each skin layer through KeraSkin-M^TM, which was previously difficult to assess in the traditional 2D cell culture system. In addition, quantification through image analysis of KeraSkin-M^TM allowed for a statistical analysis of the whitening effects. These results suggest that the KeraSkin-M^TM can be used as a new evaluation method of evaluating whitening efficacy, as well as complement the traditional total melanin content and tyrosinase inhibition assays.

• Geophysics and Geophysical Exploration
• /
• v.17 no.4
• /
• pp.187-201
• /
• 2014

Compared with the separated inversion of electromagnetic (EM) and seismic data, a joint inversion using both EM and seismic data reduces the uncertainty and gives the opportunity to use the advantage of each data. Seismic fullwaveform inversion allows velocity information with high resolution in complicated subsurface. However, it is an indirect survey which finds the structure containing oil and gas. On the other hand, marine controlled-source EM (mCSEM) inversion can directly indicate the oil and gas using different EM properties of hydrocarbon with marine sediments and cap rocks whereas it has poor resolution than seismic method. In this paper, we have developed a joint EM inversion algorithm using a cross-gradient technique. P-wave velocity structure obtained by full-waveform inversion using plane wave encoding is used as structure constraints to calculate the cross-gradient term in the joint inversion. When the jointinversion algorithm is applied to the synthetic data which are simulated for subsea reservoir exploration, images have been significantly improved over those obtained from separate EM inversion. The results indicate that the developed joint inversion scheme can be applied for detecting reservoir and calculating the accurate oil and gas reserves.

• Journal of Astronomy and Space Sciences
• /
• v.21 no.1
• /
• pp.11-28
• /
• 2004

To better understand how high-latitude electric fields influence thermospheric dynamics, winds in the high-latitude lower thermosphere are studied by using the Thermosphere-ionosphere Electrodynamics General Circulation Model developed by the National Conte. for Atmospheric Research (NCAR-TIEGCM). The model is run for the conditions of 1992-1993 southern summer. The association of the model results with the interplanetary magnetic field(IMF) is also examined to determine the influences of the IMF-dependent ionospheric convection on the winds. The wind patterns show good agreement with the WINDII observations, although the model wind speeds are generally weaker than the observations. It is confirmed that the influences of high-latitude ionospheric convection on summertime thermospheric winds are seen down to 105 km. The difference wind, the difference between the winds for IMF$\neq$O and IMF=0, during negative IMF $B_y$ shows a strong anticyclonic vortex while during positive IMF $B_y$ a strong cyclonic vortex down to 105 km. For positive IMF $B_z$ the difference winds are largely confined to the polar cap, while for negative IMF B, they extend down to subauroral latitudes. The IMF $B_z$ -dependent diurnal wind component is strongly correlated with the corresponding component of ionospheric convection velocity down to 108 km and is largely rotational. The influence of IMF by on the lower thermospheric summertime zonal-mean zonal wind is substantial at high latitudes, with maximum wind speeds being $60\;ms^-1$ at 130 km around $77^{\circ}$ magnetic latitude.

• Journal of the Institute of Electronics Engineers of Korea SC
• /
• v.45 no.2
• /
• pp.45-54
• /
• 2008

In this paper, a dynamic GTS scheduling method based on IEEE 802.15.4 is proposed for wireless control system. The proposed method can guarantee a transmission of real-time periodic and sporadic data within the time frame in factory environment. The modified superframe of IEEE 802.15.4 was used to the dynamic scheduling method of real-time mixed traffic(periodic data, sporadic data, and non real-time message). By separating CFP and CAP properly, the sporadic and non real-time messages are transmitted effectively and guarantee real-time transmission within a deadline. The simulation results show the improvement of real-time performance of periodic and sporadic data.

• Korean Journal of Construction Engineering and Management
• /
• v.3 no.4 s.12
• /
• pp.114-122
• /
• 2002

Earned Value Management System(EVMS) is a management technique that is emerging as a valuable tool in the management of all projects, including and in particular construction projects. It is based on C/SCSC that has been released by the U.S. Department of Defense (DOD) in 1967. In a project that employs the earned value management concept, the project's measurable performance plans will be formed with the creation of CAPs. The formation of CAPs is a planning step necessary to form an earned value baseline. In this paper, a method is proposed to form CAPs using Material Requirement Planning(MRP) that is also known as a useful planning tool in the manufacturing industry. An application to a real project has been carried through workpackaging model.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• v.45 no.6
• /
• pp.18-26
• /
• 2008

In this paper, dynamic GTS scheduling method based on IEEE 802.15.4 is proposed for wireless control system considering reliability and real-time property. The proposed methods can guarantee a transmission of real-time periodic and sporadic data within the limited time frame in factory environment. The superframe of IEEE 802.15.4 is used for the dynamic transmission method of real-time mixed traffic (periodic data, sporadic data, and non real-time message). By separating CFP and CAP properly, the periodic, sporadic, and non real-time messages are transmitted effectively and guarantee real-time transmission within a deadline. The simulation results show the improvement of real-time performance of periodic and sporadic data at the same time.

• Journal of the Korean GEO-environmental Society
• /
• v.13 no.3
• /
• pp.85-90
• /
• 2012

This paper deals with the results for a numerical analysis of single piles and pile groups in multi-layers soil(granite soil-clay-granite soil) subjected to monotonous lateral loading using the ABAQUS finite element software. The investigated variables in this study include free head and embedded capped single pile, pile diameter (0.5m), pile length (10m), and pile groups. Numerical analyses were conducted by variation of spacing piles(s=3D, 4D, 5D) to compare the behaviour of single pile without cap and group pile. The $1{\times}3$ pile group(leading pile, middle pile, trail pile) was selected to investigate the individual pile and group lateral resistance, the distribution of the resistance among the piles. The analysis model of clay and the material of granite soil was modeled by using Druker-Prager constitutive relationship and existing treatise respectively. The pile was considered as a elastic circular concrete pile. As a result, the more pile space was extended, the value of P-multiplier is appeared to be less effective to leading pile. The lateral resistance of single-layer showed approximately 4-20% larger than the multi-layers.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.20 no.6
• /
• pp.699-708
• /
• 2007

Reinforced concrete deep beams are general structural members used as transfer-girder, pile cap, foundation wall and so on. They have a complex stess formation. Generally, failure mechanisms differ from either continuous deep beams or simple supported deep beams. In continuous deep beams, a negative moment is occurred over intermediate support and the location of maximum moment coincide with high shear force. Therefore, failure usually occurs at this region. While on the other hand, in simple supported deep beam, the region of high shear coincides with the region of low moment. The web opening of deep beams for accepting a facility makes shear behaviors of deep beams more complex and gives rise to an expansion of crack around the opening and a decline of shear capacity of deep beams. Therefore, Engineers must determine a delicate reinforcement method to control a crack and increase a shear capacity. The purpose of this report is a computation of an effective reinforcement method through non-linear finite element method by means of adopting various reinforcement method as variables and a computation of shear capacity formula taking an effectiveness of reinforcement into consideration.