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Statistical network analysis for epilepsy MEG data

  • Haeji Lee;Chun Kee Chung;Jaehee Kim
    • Communications for Statistical Applications and Methods
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    • v.30 no.6
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    • pp.561-575
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    • 2023
  • Brain network analysis has attracted the interest of neuroscience researchers in studying brain diseases. Magnetoencephalography (MEG) is especially proper for analyzing functional connectivity due to high temporal and spatial resolution. The application of graph theory for functional connectivity analysis has been studied widely, but research on network modeling for MEG still needs more. Temporal exponential random graph model (TERGM) considers temporal dependencies of networks. We performed the brain network analysis, including static/temporal network statistics, on two groups of epilepsy patients who removed the left (LT) or right (RT) part of the brain and healthy controls. We investigate network differences using Multiset canonical correlation analysis (MCCA) and TERGM between epilepsy patients and healthy controls (HC). The brain network of healthy controls had fewer temporal changes than patient groups. As a result of TERGM, on the simulation networks, LT and RT had less stable state than HC in the network connectivity structure. HC had a stable state of the brain network.

Correlation Analysis between Forest Vegetation Type and Environment Factor in Mt. Hwaak (화악산의 산림군락과 환경요인의 상관관계 분석)

  • Yun, Chung-Weon;Kim, Hye-Jin;Yang, Hee-Moon;Lim, Jong-Hwan;Kim, Young-Kul;Shin, Joon-Hwan;Lee, Byeng-Cheon
    • Journal of Environmental Science International
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    • v.18 no.5
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    • pp.579-588
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    • 2009
  • The purpose of this study was to explain relationship between community structure and their environment variables in Mt. Hwaak. Samples were collected by 101 plots using ZM phytosociological method and followed by cluster, importance value and canonical correspondence analysis. The forest vegetation classified into 8 community types such as Pinus densiflora community, Berberis amurensis community, Betula ermani community, Betula schmidtii community, Larix leptolepis community, Pinus koraiensis community, Cornus controversa community and Salix koreensis community. Altitude was considered as the highest factor correlated to the community types. Berberis amurensis community and Betula ermani community were located in upper slope area of high elevation, Comus controversa community and Salix koreensis community in valley area, and Pinus densiflora community in ridge area, respectively.

Isolation of Novel Hepcidin Isoforms from the Rockbream Oplegnathus fasciatus (Perciformes)

  • Lee, Sang-Yoon;Nam, Yoon-Kwon
    • Fisheries and Aquatic Sciences
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    • v.14 no.1
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    • pp.31-42
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    • 2011
  • Three novel hepcidin isoforms were isolated and characterized from the perciform fish species Oplegnathus fasciatus. These hepcidin isoforms (designated rbhepc5, rbhepc6 and rbhepc7) were found to share a conserved, tripartite gene structure and a considerable sequence homology one another. A comparison of their mature peptide sequences with those of other perciform hepcidin orthologs indicated that these three hepcidin isoforms as well as four other isoforms previously identified in this species, appear to belong to the HAMP2 group of hepcidin genes. Analysis of the 5'-upstream sequences showed that the proximal non-coding regions of rbhepc5~7 do not possess canonical TATA signals; instead, they harbor several binding motifs for transcription factors involved in immune modulation. Reverse transcriptase-PCR analysis demonstrated that the rbhepc5~7 are expressed predominantly in the liver, and that the transcription of rbhepc5~7 is rapidly induced in the liver, but not in other tissues, by experimental challenge with any of three different bacterial species. However, transcription of rbhepc6 appeared to be negligible under both basal and stimulated conditions, as judged by the redundancy count of randomly chosen reverse transcriptase-PCR clones.

Population Structure of Liparis tanakae (PISCES, Liparidae) from Korea Based on Morphological and Molecular Traits (형태 및 분자 특징에 의한 한국산 꼼치(Liparis tanakae)의 집단 구조)

  • Myoung, Se Hun;Ban, Tae-Woo;Kim, Jin-Koo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.2
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    • pp.198-207
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    • 2016
  • Tanaka’s snailfish, Liparis tanakae (Gilbert and Burke, 1912), is distributed throughout the coasts of Korea. To clarify the population structure of L. tanakae, we analyzed the morphological and genetic variation among individuals sampled from three localities surrounding the Korean peninsula: Boryeong in the Yellow Sea, Jinhae in the Korea Strait and Pohang in the East Sea. Principal component analysis based on 20 morphometric characteristics revealed two slightly distinct groups (Boryeong vs. Jinhae and Pohang). However, canonical discriminant analysis clearly revealed three groups, separated according to locality. Pairwise differentiation index (FST) comparisons based on 762-base pairs mitochondrial cytochrome b gene sequences showed that Boryeong significantly differed from Jinhae and Pohang, but Jinhae and Pohang did not significantly differ from each other. Our findings suggest that Korean L. tanakae comprise at least two groups. Further studies using more sensitive DNA markers, such as microsatellite DNA, are required.

Modeling of air cushion vehicle's flexible seals under steady state conditions

  • Zalek, Steven F.;Karr, Dale G.;Jabbarizadeh, Sara;Maki, Kevin J.
    • Ocean Systems Engineering
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    • v.1 no.1
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    • pp.17-28
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    • 2011
  • The purpose of this paper is to demonstrate the efficacy of modeling a surface effect ship's air-cushion flexible seal utilizing a two-dimensional beam under steady state conditions. This effort is the initial phase of developing a more complex three-dimensional model of the air-seal-water fluid-structure interaction. The beam model incorporates the seal flexural rigidity and mass with large deformations while assuming linear elastic material response. The hydrodynamic pressure is derived utilizing the OpenFOAM computational fluid dynamic (CFD) solver for a given set of steady-state flow condition. The pressure distribution derived by the CFD solver is compared with the pressure required to deform the seal beam model. The air pressure, flow conditions and seal geometry are obtained from experimental analysis. The experimental data was derived from large-scale experimental tests utilizing a test apparatus of a canonical surface effect ship's flexible seal in a towing tank over a variety of test conditions.

Composition and Abundance of Wood-Boring Beetles Inhabited by Pine Trees

  • Park, Yonghwan;Jang, Taewoong;Won, Daesung;Kim, Jongkuk
    • Journal of Forest and Environmental Science
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    • v.35 no.3
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    • pp.189-196
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    • 2019
  • Plants are consumed by a myriad of organisms that compete for resources. Direct interactions among multiple plant-feeding organisms in a single host can range for each species from positive to negative. Wood-boring beetle faces a number of biotic and abiotic constraints that interfere with the good prospects from the tree. Biotic factors, including arthropod pests and diseases, and abiotic factors, such as drought and water-logging, are the major constraints affecting the species. The present study aimed to provide basic data for analyzing forest health, identify the kinds of wood-boring beetles in the central part of Korea. Our second goal was to analyze the species composition and diversity of regional communities and to examine. A total of 10,461 individual wood-boring beetles belonging to 8 families and 50 species attracted to trap trees in the pine forests were recorded during the study period on study sites. The results of the analysis of collected species showed that the community structure on all study sites was similar. Seasonal occurrences of dominant wood-boring beetles (5 species) from each study site showed the highest number of all species, except for Siphalinus gigas in May, followed by a gradual decline, and the largest number of Siphalinus gigas appeared in June. The similarity index of species composition was relatively high, ranging from 0.75 to 0.90 for each study site.

Distribution Characteristics and Community Structure of Phytoplankton in the Different Water Masses During Early Summer of Southern Sea of Korea (초여름 남해광역권의 수괴별 식물플랑크톤 군집구조 특성)

  • Baek, Seung-Ho;Shin, Kyoung-Soon;Hyun, Bong-Gil;Jang, Pung-Guk;Kim, Hyun-Su;Hwang, Ok-Myung
    • Ocean and Polar Research
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    • v.32 no.1
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    • pp.1-13
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    • 2010
  • To assess short-term variation of summer phytoplankton community structure in different water masses, phytoplankton and environmental factors were monitored from 31 stations on and off the southern coasts of Korea, from June 18 to June 20 2009. According to multidimensional scaling (MDS) and cluster analysis based on phytoplankton community data from each station, the southern sea was divided into two groups. The first group included stations in the south-eastern region of Jeju Island, which is strongly influenced by the Kuroshio warm current. The second group located along the coastal region of the southern sea, which was mainly comprised of Bacillariophyceae and Crytophyceae. Of these stations, St. 13 and 28 formed a temperature front caused by different hydrological conditions. In particular, nutrients and Chl.a concentrations in these two stations were significantly higher compared to those in the other stations. This indicates that phytoplankton population and subsequent microalgal growth under high nutrient concentrations vary in different water masses. Our results support the theory that phytoplankton community structure in the southern sea of Korea can be influenced on a short-term scale by different water masses and currents.

Analysis of Archaeal Communities in Full-Scale Anaerobic Digesters Using 454 Pyrosequencing (454 Pyrosequencing을 이용한 실규모 혐기성 소화조의 아케아 군집구조 분석)

  • Kang, Hyun-Jin;Kim, Taek-Seung;Lee, Young-Haeng;Lee, Taek-June;Han, Keum-Suk;Choi, Young-Jun;Park, Hee-Deung
    • Korean Journal of Microbiology
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    • v.47 no.3
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    • pp.209-217
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    • 2011
  • Archaeal communities were investigated using 454 pyrosequencing technology based on 16S rRNA gene in 11 samples collected from six different full-scale anaerobic digesters. Observed operational taxonomic units (OTUs) estimated from the archaeal 16S rRNA gene sequences were 13-55 OTUs (3% cutoff) which was corresponded to 29-89% of Chao1 richness estimates. In the anaerobic digesters there were archaeal sequences within the orders Thermoproteales, Thermoplasmatales, Desulfurococcales as well as within the orders Methanomicrobiales, Methanobacteriales, Methanococcales, Methanosarcinales, and Methanocellales, which are known to produce methane. Among these orders, Methanococcales known to produce methane using hydrogen was the predominant taxon and constituted 51.8-99.7% of total sequences. All samples showed a very similar community structure (Pearson correlation coefficient=0.99) except for one sample based on a heat map analysis. In addition, canonical correspondence analysis correlating archaeal communities to the environmental variables demonstrated that digester temperature and total solids removal rate were the two important explanatory variables. Overall results suggested that environmental and operational variables of anaerobic digester are important factors determining archaeal diversity and community structure.

Adsorption Characteristics of Nitrogen in Carbonaceous Micropore Structures with Local Molecular Orientation (국부분자배향의 탄소 미세기공 구조에 대한 질소의 흡착 특성)

  • Seo, Yang Gon
    • Clean Technology
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    • v.28 no.3
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    • pp.249-257
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    • 2022
  • The adsorption equilibria of nitrogen on a region of nanoporous carbonaceous adsorbent with local molecular orientation (LMO) were calculated by grand canonical Monte Carlo simulation at 77.16 K. Regions of LMO of identical size were arranged on a regular lattice with uniform spacing. Microporosity was predominately introduced to the model by removing successive out-of-plane domains from the regions of LMO and tilting pores were generated by tilting the basic structure units. This pore structure is a more realistic model than slit-shaped pores for studying adsorption in nanoporous carbon adsorbents. Their porosities, surface areas, and pore size distributions according to constrained nonlinear optimization were also reported. The adsorption in slit shaped pores was also reported for reference. In the slit shaped pores, a clear hysteresis loop was observed in pores of greater than 5 times the nitrogen molecule size, and in capillary condensation and reverse condensation, evaporation occurred immediately at one pressure. In the LMO pore model, three series of local condensations at the basal slip plane, armchair slip plane and interconnected channel were observed during adsorption at pore sizes greater than about 6 times the nitrogen molecular size. In the hysteresis loop, on the other hand, evaporation occurred at one or two pressures during desorption.

Analysis for the relationship of environmental factors and vegetation structure at natural streamside valley and riparian forest in South Korea

  • Cho, Kyu-Tae;Jang, Rae-Ha;You, Young-Han
    • Journal of Ecology and Environment
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    • v.38 no.4
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    • pp.405-413
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    • 2015
  • We classified the streamside plant community by phyto-sociological method and analyzed the relationship between environment factors and vegetation structure by using the classification and ordination method. We found that twenty one plant communities were classified according to dominant species at the natural streamside valley forest with surveying the 65 quadrats (10 m × 10 m). From the survey results, the hardwood plant communities were classified as streamside valley forest and the softwood plant communities as riparian forest according to the degree of flooding. The valley forest had a distribution of 17 plant communities which was 65% (42 quadrats) of 65 quadrats: Maackia amurensis community, Betula davurica community, Quercus variabilis community, Pinus densiflora community, Q. serrata community, Prunus sargentii community, and Meliosma oldhamii community etc. The riparian forest had a distribution of four plant communities which was 35% (23 quadrats) of 65 quadrats: Salix koreensis community, S. rorida community, S. purpurea var. japonica community, and S. glandulosa community, etc. From the two-way indicator species analysis (TWINSPAN) analysis, we found indicator species Oplismenus undulatifolius and Lindera obtusiloba for the streamside valley forest and Humulus japonicus, Phragmites japonica, and S. koreensis for the riparian forest. From the results of the canonical correspondence analysis (CCA), coordinates, altitude, and stream structure showed low correlation to the distribution of the plant community. Therefore, it seemed that valley forest and riparian forest were distinguished by the stream gradient and waterway width which determined by the stream water level.