• Title/Summary/Keyword: Canonical Structure

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The Design of Variable Structure Controller for the System in Phase Canonical Form with Incomplete State Measurements (비 측정 상태변수를 갖는 위상 표준형계통에 대한 가변구조 제어기의 설계)

  • 박귀태;최중경
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.41 no.8
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    • pp.902-913
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    • 1992
  • There have been several control schemes for the single input systems with unmeasurable state variables using variable structure control(VSC) theory. In the previous VSC, the systems must be represented in phase canonical form and the complete measurements for each state variable must be assumed. In order to eliminate these restrictions several VSC methods were proposed. And especially for the systems in phase canonical form with unmeasurable state variables, the reduced order switching function algorithm was proposed. But this method has many drawbacks and can not be used in the case of general form (not phase canonical form) dynamic system. Therefore this paper propose new construction method of switching fuction for the systems in phase canonical form, which reduce the restriction of reduced order switching function algorithm. And this algorithm can be realized for any state representation and adopted in the systems where not all states are available for switching function synthesis or control.

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The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNA-Induced Silencing of NF-κB-Inducing Kinase

  • Jang, Hanbit;Park, Seulki;Kim, Jaehoon;Kim, Jong Hwan;Kim, Seon-Young;Cho, Sayeon;Park, Sung Goo;Park, Byoung Chul;Kim, Sunhong;Kim, Jeong-Hoon
    • Molecules and Cells
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    • v.43 no.1
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    • pp.23-33
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    • 2020
  • NF-κB signaling through both canonical and non-canonical pathways plays a central role in immune responses and inflammation. NF-κB-inducing kinase (NIK) stabilization is a key step in activation of the non-canonical pathway and its dysregulation implicated in various hematologic malignancies. The tumor suppressor, p53, is an established cellular gatekeeper of proliferation. Abnormalities of the TP53 gene have been detected in more than half of all human cancers. While the non-canonical NF-κB and p53 pathways have been explored for several decades, no studies to date have documented potential cross-talk between these two cancer-related mechanisms. Here, we demonstrate that p53 negatively regulates NIK in an miRNA-dependent manner. Overexpression of p53 decreased the levels of NIK, leading to inhibition of the non-canonical NF-κB pathway. Conversely, its knockdown led to increased levels of NIK, IKKα phosphorylation, and p100 processing. Additionally, miR-34b induced by nutlin-3 directly targeted the coding sequences (CDS) of NIK. Treatment with anti-miR-34b-5p augmented NIK levels and subsequent non-canonical NF-κB signaling. Our collective findings support a novel cross-talk mechanism between non-canonical NF-κB and p53.

A Study on the Synthesis of a Dual-Mode Asymmetric Canonical Filter (이중모드 비대칭 Canonical 구조 필터의 합성에 대한 연구)

  • 엄만석;이주섭;염인복;이성팔
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.6
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    • pp.599-605
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    • 2003
  • A dual-mode asymmetric canonical filter is widely used in an input demultiplexer for satellite transponder. This paper deals with a simple synthesis method fur an asymmetric canonical filter. The coupling matrix of an asymmetric canonical filter is obtained by applying plane rotation technique to the coupling matrix of a symmetric canonical filter. This paper gives a list of pivots and rotation angles to obtain the coupling matrix of asymmetric canonical structure filters. The coupling matrix of 8th and 10th order asymmetric canonical filter is obtained by this proposed method. It is shown that the frequency response of asymmetric canonical filter is identical to that of symmetric canonical filter.

A Dual-Mode Canonical Filter with Dual-Passband for Satellite Transponder (두 개의 통과대역을 갖는 위성 중계기용 이중모드 정규(Canonical) 구조 필터)

  • 이주섭;엄만석;염인복;박종흥
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.3
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    • pp.278-283
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    • 2004
  • Due to the complex arrangement of frequency plans and spatial overages in modern satellite communications, channels that are non-contiguous in frequency may be amplified by a single power amplifier and transmitted to the ground through one beam. In this paper, a dual-mode canonical filter with dual-passband is presented. The filter adopts dual-mode technique for mass and volume reduction. Canonical structure is adopted for maximum transmission zero realization. To validate the design technique, a 6-pole dual-mode canonical dual-passband filter for Ka-band(30/20 ㎓) satellite transponder is realized. The measured frequency response of the filter shows good agreement with the computed one.

A Design of Variable Structure Controller for the General Single Input Systems with Unmeasurable State Variables (측정불가능한 상태변수를 갖는 일반적인 단일 입력 계통에 대한 가변구조 제어기의 설계)

  • 박귀태;최중경
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.41 no.7
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    • pp.773-783
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    • 1992
  • There have been several control schemes for the single input systems with unmeasurable state variables using variable structure control(VSC) theory. However, each of them is a study on the systems which can be represented in the phase canonical form or non-phase canonical form dynamic equation separately. As these control algorithms have difficulties in practical application by its theoretical limitations, in this paper we propose a new VSC theory which overcomes those limitations, in this paper we propose a new VSC theory which overcomes those limitations of proposed schemes. This new control scheme can be realized for the general linear systems which have unmeasurable state variables. And the switching function of this VSS algorithm consists of measurable state variable function(reduced-order switching function) and its derivatives. Also in the construction of control imput only measurable state variables are used.

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Variation of Cannonical Sentence Structure in Korean & Japanese Dialects & its Implication

  • Khym, Han-gyoo
    • International Journal of Internet, Broadcasting and Communication
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    • v.7 no.2
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    • pp.142-148
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    • 2015
  • The main purpose of this squib is to provide a new principled account for variation of canonical sentence structure in Korean and Japanese based on the linguistic data commonly observed in some dialects of Korean and Japanese. Unlike the English case in which Comp(lementizer) such as 'that' in an embedded clause freely drops as far as the ECP (Lasnik & Saito 1992) is obeyed, some dialects of both Korean and Japanese show interesting linguistic data very different from those of English, thereby leading us to reasonably doubt the traditionally-accepted paradigm of the canonical sentence structure of CP for all languages. In this squib I propose, based on Korean & Japanese dialects and by developing the Minimal Structure Principle (MSP) ($Bo{\check{s}}kovi{\acute{c}}$ 1997, p. 25), that the cannonical structure of a sentence is not fixed, from the beginning at all, to be one single maximal category, CP. Instead, it should be decided to be either CP or IP, based on the feature of [${\pm}$markedness] and MSP, and the marked (or non-cannonical) embedded sentence needs to satisfy ECP for adjacency (or feature-licensing by the matrix verb in the MP terminology).

UNIFYING STATIONARY EQUATIONS FOR GENERALIZED CANONICAL CORRELATION ANALYSIS

  • Kang Hyun-Cheol;Kim Kee-Young
    • Journal of the Korean Statistical Society
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    • v.35 no.2
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    • pp.143-156
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    • 2006
  • In the present paper, various solutions for generalized canonical correlation analysis (GCCA) are considered depending on the criteria and constraints. For the comparisons of some characteristics of the solutions, we provide with certain unifying stationary equations which might to also useful to obtain various generalized canonical correlation analysis solutions. In addition, we suggest an approach for the generalized canonical correlation analysis by exploiting the concept of maximum eccentricity originally de-signed to test the internal independence structure. The solutions, including new one, are compared through unifying stationary equations and by using some numerical illustrations. A type of iterative procedure for the GCCA solutions is suggested and some numerical examples are provided to illustrate several GCCA methods.

A canonical structure for nonlinear observers

  • Nam, Kwang-Hee;Lee, Won-Chang
    • 제어로봇시스템학회:학술대회논문집
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    • 1988.10b
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    • pp.939-942
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    • 1988
  • In order to construct a nonlinear observer, change of coordinate system is necessary. However, as in the case of feedback linearizable system it is not easy to obtain a coordinate transformation map. ln this paper, a canonical structure is proposed for observable systems with an objective of finding a vector field which is necessary for the generation of a new coordinate system.

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Structure and Stability of γ-Aminobutyric acid-(H2O)n (n = 0-5) Clusters: Zwitterionic vs. Canonical forms

  • Kim, Ju-Young;Schermann, Jean Pierre;Lee, Sung-Yul
    • Bulletin of the Korean Chemical Society
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    • v.31 no.1
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    • pp.59-63
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    • 2010
  • Calculations are presented for the $\gamma$-aminobutyric acid-$(H_2O)_n$ (n = 0-5) clusters in both canonical and zwitterionic forms. We examine the effects of microsolvation on the structures and transformation between the canonical and zwitterionic forms. The canonical forms are predicted to be more stable for n = 0-4. With five microsolvating water molecules, the two forms of $\gamma$-aminobutyric acid become quasidegenerate, with the energies of zwitterionic forms slightly (by 1 - 3 kcal/mol) higher. The lowest energy zwitterionic conformer of $\gamma$-aminobutyric acid-$(H_2O)_5$ cluster is calculated to isomerize to canonical form through a barrier-less proton transfer process and is thus predicted to be kinetically unstable. Therefore, we predict that the canonical conformers of $\gamma$-aminobutyric acid should be observed predominantly in the gas phase at low temperature in presence of up to five water molecules.