• Title/Summary/Keyword: CRAM

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Study of Electrophoretic Karyotypes of Fusarium Section Liseola (Fusarium 균의 section Liseola에 대한 핵형 연구)

  • 밍병례;안미선;최영길
    • Korean Journal of Microbiology
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    • v.35 no.3
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    • pp.192-196
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    • 1999
  • CHEF-PFGE(Contour-Clarnped Homogeneous Electric field- Pulsed Field Gel Electrophoresis) was used to identify electrophoretic karyotype for eight strains belonging to the Fzisoriuni section Liseolo. Chromosome numbers were nine to thirteen bands, ranging in size Cram 0.75 to 6.45 Mb. The total genome size was eslimated to range from 38.19 Mb to 43.12 Mb and numerous chromosome-length polymorphisms (CLPs) were observed. For the chromosome localizalion of the gene, 1GS sequence(2.6 Kb) of rDNA from F: moniliforme, chs-2 gene(2.8 Kb) and 4 - 3 gene(3.8 Kb) from Neuuospora cmssa were wed as probes.

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Synthesis and in Vitro Antibacterial Activity of Cephalosporins with a Pyridiniume Substituent Carrying an Isoxazole Moiety at the C-3 Position

  • Park, Hae-Il;Choi, Hyun-Joo;Jang, Jin-Hee;Choi, Sung-Hak;Rhee, Jae-Keol;Chang, Min-Sun
    • Archives of Pharmacal Research
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    • v.24 no.2
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    • pp.89-94
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    • 2001
  • Several quaternary pyridinium cephalosporin analogues were prepared analogues were Prepared and evaluated in vitro for antibacterial activity against selected Gram-positive and Cram-negative organisms. Most of the synthesized analogues were either as effective or less effective against the tested bacterial organ isms than the reference com pounds, Cefpirome and Ceftazidime.

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A Linear Prediction Based Estimation of Signal-to-Noise Ratio in AWGN Channel

  • Kamel, Nidal S.;Jeoti, Varun
    • ETRI Journal
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    • v.29 no.5
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    • pp.607-613
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    • 2007
  • Most signal-to-noise ratio (SNR) estimation techniques in digital communication channels derive the SNR estimates solely from samples of the received signal after the matched filter. They are based on symbol SNR and assume perfect synchronization and intersymbol interference (ISI)-free symbols. In severe channel distortion where ISI is significant, the performance of these estimators badly deteriorates. We propose an SNR estimator which can operate on data samples collected at the front-end of a receiver or at the input to the decision device. This will relax the restrictions over channel distortions and help extend the application of SNR estimators beyond system monitoring. The proposed estimator uses the characteristics of the second order moments of the additive white Gaussian noise digital communication channel and a linear predictor based on the modified-covariance algorithm in estimating the SNR value. The performance of the proposed technique is investigated and compared with other in-service SNR estimators in digital communication channels. The simulated performance is also compared to the Cram$\acute{e}$r-Rao bound as derived at the input of the decision circuit.

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Comparing the empirical powers of several independence tests in generalized FGM family

  • Zargar, M.;Jabbari, H.;Amini, M.
    • Communications for Statistical Applications and Methods
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    • v.23 no.3
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    • pp.215-230
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    • 2016
  • The powers of some tests for independence hypothesis against positive (negative) quadrant dependence in generalized Farlie-Gumbel-Morgenstern distribution are compared graphically by simulation. Some of these tests are usual linear rank tests of independence. Two other possible rank tests of independence are locally most powerful rank test and a powerful nonparametric test based on the $Cram{\acute{e}}r-von$ Mises statistic. We also evaluate the empirical power of the class of distribution-free tests proposed by Kochar and Gupta (1987) based on the asymptotic distribution of a U-statistic and the test statistic proposed by $G{\ddot{u}}ven$ and Kotz (2008) in generalized Farlie-Gumbel-Morgenstern distribution. Tests of independence are also compared for sample sizes n = 20, 30, 50, empirically. Finally, we apply two examples to illustrate the results.

Cyclic Host Having Double Bonds as Bridging Units

  • Kyung-Soo Paek;Donald J. Cram
    • Bulletin of the Korean Chemical Society
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    • v.10 no.6
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    • pp.568-572
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    • 1989
  • Terphenyl dialdehyde 6 was obtained in 17.4% overall yield through oxidative coupling, methylation, and bisformylation reactions starting from p-cresol, and then coupled intermolecularly using McMurry reaction to give 22-membered macrocylic host 7 in 14.4% yield. In crystal structure host 7 has $C2_v$ symmetry with cis-cis configuration of two double bonds. Four methoxy groups adjacent to double bonds and the other two methoxy groups are directed opposite side, forming a cavity which can nest a guest. The cavity is filled by two inward-turned methyl groups out of four methoxy groups adjacent to double bonds. The kinetically controlled reaction mechanism leading to cis product was proposed. The cation binding properties of 7 were obtained using picrate extraction experiment from $D_2O\; into\; CDCl_3\; at\; 25^{\circ}C$. All the spherical cations (from $Li^+ to NH4^+)$ are complexed with free energies of $7.3{\pm}0.3$ kcal/mol.

Chiral Host. Attempted Synthesis Using McMurry Reaction as a Final Ring Closure Method

  • Kyung-Soo Paek;Donald J. Cram
    • Bulletin of the Korean Chemical Society
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    • v.10 no.6
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    • pp.572-577
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    • 1989
  • Using the low valent titanium induced carbonyl-carbonyl coupling reaction, it was attempted to synthesize sterically hindered 17-membered cyclic chiral host 2. The semifinal dialdehyde 12 was obtained through 11 step reactions beginning from p-tert-butylphenol and dibenzofuran. When dialdehyde 12 was treated with $TiCl_3-Zn/Cu,$ only intermolecularly coupled dimer 14 was obtained instead of intramolecularly coupled cyclic alkene 2. The mechanistic consideration leading to 14 was discussed and the cation binding properties of dimer 14 and dicarboxylic intermediate 13 was reported, which implies the significance of the principle of preorganization of host's binding sites prior to complexation.

Fault injection and failure analysis on Xilinx 16 nm FinFET Ultrascale+ MPSoC

  • Yang, Weitao;Li, Yonghong;He, Chaohui
    • Nuclear Engineering and Technology
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    • v.54 no.6
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    • pp.2031-2036
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    • 2022
  • Energetic particle strikes the device and induces data corruption in the configuration memory (CRAM), causing errors and even malfunctions in a system on chip (SoC). Software-based fault injection is a convenient way to assess device performance. In this paper, dynamic partial reconfiguration (DPR) is adopted to make fault injection on a Xilinx 16 nm FinFET Ultrascale+ MPSoC. And the reconfiguration module implements the Sobel and Gaussian image filtering, respectively. Fault injections are executed on the static and reconfiguration modules' bitstreams, respectively. Another contribution is that the failure modes and effects analysis (FMEA) method is applied to evaluate the system reliability, according to the obtained injection results. This paper proposes a software-based solution to estimate programmable device vulnerability.

Validation of nuclide depletion capabilities in Monte Carlo code MCS

  • Ebiwonjumi, Bamidele;Lee, Hyunsuk;Kim, Wonkyeong;Lee, Deokjung
    • Nuclear Engineering and Technology
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    • v.52 no.9
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    • pp.1907-1916
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    • 2020
  • In this work, the depletion capability implemented in Monte Carlo code MCS is investigated to predict the isotopic compositions of spent nuclear fuel (SNF). By comparison of MCS calculation results to post irradiation examination (PIE) data obtained from one pressurized water reactor (PWR), the validation of this capability is conducted. The depletion analysis is performed with the ENDF/B-VII.1 library and a fuel assembly model. The transmutation equation is solved by the Chebyshev Rational Approximation Method (CRAM) with a depletion chain of 3820 isotopes. 18 actinides and 19 fission products are analyzed in 14 SNF samples. The effect of statistical uncertainties on the calculated number densities is discussed. On average, most of the actinides and fission products analyzed are predicted within ±6% of the experiment. MCS depletion results are also compared to other depletion codes based on publicly reported information in literature. The code-to-code analysis shows comparable accuracy. Overall, it is demonstrated that the depletion capability in MCS can be reliably applied in the prediction of SNF isotopic inventory.

Expression of Sortase, a Transpeptidase for Cell Wall Sorting Reaction, from Staphylococcus aureus ATCC 6538p in Escherichia coli

  • LEE, KI-YOUNG;DONG-SUN SHIN;JUNG-MIN YOON;HEONJOONG KANG;KI-BONG OH
    • Journal of Microbiology and Biotechnology
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    • v.12 no.3
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    • pp.530-533
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    • 2002
  • This paper describes the development of an enzymatic assay system for the identification of specific inhibitors of sortase, a transpeptidase that cleaves surface proteins of Cram-positive bacteria, from Staphylococcus aureus ATCC 6538p for antibacterial drug discovery. The coding region of the enzyme was amplified with the exception of the N-terminal membrane anchor sequence, cloned into a vector providing His-Patch-thioredoxin-tag at the N-terminus, expressed in Escherichia coli, and purified by metal chelate affinity chromatography. The enzyme activity was determined by quantifying increased fluorescence intensity upon cleavage of synthetic Dabcyl-QALPETGEE-Edans peptide. The results suggest that the developed in vitro assay system call be used in the search for sortase inhibitors In a short period of time.

Construction of bivariate asymmetric copulas

  • Mukherjee, Saikat;Lee, Youngsaeng;Kim, Jong-Min;Jang, Jun;Park, Jeong-Soo
    • Communications for Statistical Applications and Methods
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    • v.25 no.2
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    • pp.217-234
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    • 2018
  • Copulas are a tool for constructing multivariate distributions and formalizing the dependence structure between random variables. From copula literature review, there are a few asymmetric copulas available so far while data collected from the real world often exhibit asymmetric nature. This necessitates developing asymmetric copulas. In this study, we discuss a method to construct a new class of bivariate asymmetric copulas based on products of symmetric (sometimes asymmetric) copulas with powered arguments in order to determine if the proposed construction can offer an added value for modeling asymmetric bivariate data. With these newly constructed copulas, we investigate dependence properties and measure of association between random variables. In addition, the test of symmetry of data and the estimation of hyper-parameters by the maximum likelihood method are discussed. With two real example such as car rental data and economic indicators data, we perform the goodness-of-fit test of our proposed asymmetric copulas. For these data, some of the proposed models turned out to be successful whereas the existing copulas were mostly unsuccessful. The method of presented here can be useful in fields such as finance, climate and social science.