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A Study on Cho Heon-yeong's Buinbyeongchiryobeob (婦人病治療法) - Focused on Medical Ideology and Prescription (조헌영의 『부인병치료법(婦人病治療法)』 연구: 의학사상과 처방을 중심으로)

  • Dowon Kim;Wung-Seok Cha
    • The Journal of Korean Medical History
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    • v.34 no.1
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    • pp.11-22
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    • 2021
  • In this study, we examine Cho Heon-yeong's medical theory in obstetrics and gynecology by looking at the contents and prescriptions of 『Buinbyeongchiryobeob (婦人病治療法)』. This book is a clinical text on obstetrics and gynecology written in the 1940's. This book consists of an Introduction, Jeungchi (證治), Yangjinhanchi (洋診漢治), Cheobangnonhae (處方論解) and refers to 『Donguibogam(東醫寶鑑)』, 『Keongakjeonseo (景岳全書)』, 『Junguihaksajeon (中醫學辭典)』, 『Jejungsinpyeon (濟衆新編)』, 『Uihakipmun (醫學入門)』 and 『UijongKeumkam (醫宗金鑑)』. Cho Heon-yeong's theory in this book has the following characteristics. First, his medical eclecticism is centered on Korean Medicine, with incidental use of Western medicine. Second, he regarded weakness (虛證) as a vital factor in obstetrics and gynecology. Third, he added "mental state" to the list of basic physiological characteristics of women. Fourth, he presented a new diagnostic standard based on a spectrum of fire (火) and cold (冷). There are 363 prescriptions in this book, and 171 of them are from 『Donguibogam (東醫寶鑑)』. The books frequently used prescriptions are all designed to supplement (補藥). There are 48 prescriptions that original to Cho Heon-yeong. Additionally, this book contains eopsaeng (攝生) and pretended stimulation therapies and exercise methods.

Cryopreservation of CHO Cell using Serum-Free Media (무혈청 배지를 이용한 CHO 세포의 동결보존)

  • Kim, Yoo-Kang;Park, Hong-Woo;Choe, Tae-Boo
    • KSBB Journal
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    • v.21 no.2
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    • pp.110-117
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    • 2006
  • During routine maintenance, animal cell lines are commonly cryopreserved in growth medium containing serum with 10% DMSO. But, in case of bioprocess under the serum-free conditions, including cultivation of cell lines and producing of pharmaceuticals, the cryopreservation should be executed without serum to prevent a cross-contamination. This experiments were performed to investigate the effects of the serum-free cryopreservation on the CHO cells. To improve the survival rates of the cryopreserved CHO cells in serum-free condition, first, the effects of permeable and non-permeable additives for substitute serum on cell viability were investigated. The combination of 10% DMSO and 0.03 M raffinose in MEM-${\alpha}$ without serum indicated 76% of cell viability. However, it did not reach the survival rates(more than 95%) of the conventional cryopreservation. In the second, to evaluate the cryopreservative ability of the serum-free medium(SFM) we compared viability of the CHO cells cryopreserved in the SFMs(Sigma C5467, C4726, and C1707, JBI SF486 and PF486), the cryoprotectant(Genenmed CAN-1000) and the MEM-${\alpha}$ with serum. All solution contained 10% DMSO. As a result of the comparison, cryopreserved cells in the SFMs showed over 95% of viability and appeared predominant viability better than cryoprotectant CAN-1000. Finally, we assessed the stability of the CHO cells in the long-term cryopreservation(LTC) using SFM. Every three months, the cryopreserved CHO cells were thawed to estimate the cell viability and the recovery rates. Then, real-time RT-PCR analyzed the inserted CHO DHFR gene. All results for the LTC appeared the same stability as the serum containing cryopreservation. In the conclusion, it could be seen that the LTC in the SFM can substitute for serum using methods in the bioprocess proceeded by CHO cells for more than 18 months.

COMPETITION INDICES OF STRONGLY CONNECTED DIGRAPHS

  • Cho, Han-Hyuk;Kim, Hwa-Kyung
    • Bulletin of the Korean Mathematical Society
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    • v.48 no.3
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    • pp.637-646
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    • 2011
  • Cho and Kim [4] and Kim [6] introduced the concept of the competition index of a digraph. Cho and Kim [4] and Akelbek and Kirkland [1] also studied the upper bound of competition indices of primitive digraphs. In this paper, we study the upper bound of competition indices of strongly connected digraphs. We also study the relation between competition index and ordinary index for a symmetric strongly connected digraph.

Tests for Seasonal Cointegrating Vectors

  • Seong, Byeong-C.;Cho, Sin-S.;Ahn, Sung-K.
    • Proceedings of the Korean Statistical Society Conference
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    • 2003.10a
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    • pp.275-279
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    • 2003
  • We obtain the asymptotic distributions of tests statistics for various types of seasonal cointegration based on GRR estimators of Ahn and Cho (2003). These tests are useful in testing for restrictions about cointegrating vectors after Chi-square tests for CCI and common PCIV in Ahn and Cho (2003) or tests for the known CCI and the known PCIVs have been performed.

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Scrambling in Koran: A Marker-based Approach

  • Cho, Sae-Youn;Choe, Jong-Joo
    • Language and Information
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    • v.5 no.1
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    • pp.73-85
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    • 2001
  • The purpose of this paper is to explore the relationship between nominal markers and scrambling in Korean by providing proper LP constraints based on Cho &Chai (2000) anc Cho & Choe(2001). In doing so, we introduce a new type marker which includes case, postpositions and delimiters and propose the Adjunct LP Constraint and the Argument LP Constraint. Our LP constraints presents a solution to the problems of the previous analyses such as Kuno's (1980) Crossing-Over Constraint. The newly postulated type marker enables us to account for the scrambling possibilities of the NPs containing cases as well as postpositions and delimiters.

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