• The Journal of the Korea Contents Association
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• v.10 no.11
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• pp.371-379
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• 2010

This study analyzes relative efficiency analysis for universities or colleges of Chung Cheong regions using data envelopment analysis. The main results of this study can by summarized as follows. First, in case of efficiency for CCR, the number of efficient universities(CCR value is one) are five universities. and mean value of CCR for universities located in Chungbuk region was most high. Second, the number of efficient colleges(CCR value is one) are three colleges. and mean value of CCR for colleges located in Daejeon region was most high. Third, in case of efficiency for BCC, the number of efficient universities(BCC value is one) are nine universities. and mean value of BCC for universities located in Chungbuk region was most high. Fourth, the number of efficient colleges(BCC value is one) are seven colleges. and mean value of BCC for colleges located in Chungbuk region was most high.

• Journal of the Korean Society for Library and Information Science
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• v.47 no.3
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• pp.275-293
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• 2013

This study conducted comparative analysis of cataloging descriptions and rules in KCR 4 and CCR 2, as follows, for the purpose of seeking understanding of classical materials cataloging rules and networking of oriental historical data cataloging (bibliographical descriptions). First, to compare the general rules, the objects of descriptions and composition of descriptions, recording order, and punctuation and information source of descriptions were analyzed. As a result, KCR 4 is more detailed in terms of author role identifications and information source regulations and CCR2 is more detailed in terms of regulations related to printing and publications and serial publications. Second, to compare the details, the main titles and liability indications, edition details, publication details and format details, and note details. As a result, regarding the description of edition type and publication details, KCR4 has detailed regulations and CCR2 has characteristic summary in terms of note details.

• Journal of Plant Biotechnology
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• v.38 no.4
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• pp.278-284
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• 2011

The CCR4-CAF1-NOT complex-mediated degradation of mRNA is a fundamental aspect of gene regulation in eukaryotes. We herein examined the role of AtCAF1 in the innate immune and wound responses of plants. Our results showed that overexpression of AtCAF1 significantly downregulated the transcript level of EFR but not FLS2 and BRI1, as well as abolished up-regulated expression pattern of EFR in response to wounding. Consistently, Agrobacteriummediated transient expression of GUS was highly enhanced in the transgenic plants overexpressing AtCAF. Furthermore, JA responsive genes were down-regulated by overexpression of AtCAF, causing the transgenic plants overexpressing AtCAF more susceptible to necrotrophic fungal pathogen, Botrytis cinerea. These results suggest that The CCR4-CAF1-NOT complex-mediated degradation of mRNA negatively regulates wounding-mediated disease resistance in Arabidopsis thaliana.

• Journal of the Korea Society of Computer and Information
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• v.16 no.12
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• pp.71-81
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• 2011

The EMR management services can monitoring the patients' record with any doctors in any hospital by using the internet and smartphones online. To handle the real time, multidimensional, continuous data, database management systems (DBMS) must cope with high insert rates for updates, however the traditional DBMS suffers from processing these kinds of data due to its serious design bottlenecks. So the researchers put forward to Data Stream Management System (DSMS). In this paper we describe the real-time Data Stream Server for Continuity of Care Record (CCR) that including continuos query processor. This system is compiled with DSMS and DBMS in EMR system for processing and monitoring the coming CCR data stream, and also storing the processed result with high-efficiency. The system enables users not only to query stored CCR information from DBMS, but also to execute continue query on real-time CCR Data Stream, and health information can be transferred between different healthcare providers that would reduce medical error. At last, we develop a IPhone mobile application to test the proposed real-time data stream server.

• International Area Studies Review
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• v.20 no.2
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• pp.63-83
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• 2016

This paper examines the determinants of efficiency in a KOSDAQ-listed manufacturing firm. We use Data Envelopment Analysis (DEA) to estimate the efficiency of the export manufacturing firm. We employ two inputs (number of employees, equity) and one output (sales) in the DEA. The determinants of export manufacturing firm efficiency are estimated using the panel Tobit model. An analysis of 369 export manufacturing firms from 2013 to 2015 indicates the following results: First, the R&D intensity, the wage and salary intensity, total asset, and equity ratio each had a negative impact on both the CCR and BCC efficiency scores. However, export intensity had a negative impact on CCR efficiency scores in a KOSDAQ-listed total export manufacturing firm. Second, the R&D intensity had a positive impact on both the CCR and BCC efficiency scores, but export intensity, the wage and salary intensity, and equity ratio each had a negative impact on the CCR and BCC efficiency scores in a KOSDAQ-listed large export manufacturing firm. Third, the R&D intensity, the wage and salary intensity, total asset, and equity ratio each had a negative impact on both the CCR and BCC efficiency scores; respectively, in a KOSDAQ-listed small and medium export manufacturing firm.

• Biomedical Science Letters
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• v.12 no.3
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• pp.145-151
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• 2006

Leukotactin-l (Lkn-l )/CCL15 has been known as a potent chemoattractant of leukocytes. However, the precise function of Lkn-l in human neutrophils has not been explained well. In the present study, we investigated the contribution of Lkn-1 in chemotactic activity of human neutrophils. Both CCR1 and CCR3 mRNA expressions are strongly expressed in human neutrophils but CCR2 protein expression was uniquely detected on the cell surface. Lkn-l binding to CCR1 and CCR3 induced chemotactic activity of neutrophils. Chemotactic index of Lkn-l was comparable to that of IL-8. $MIP-1{\alpha}/CCL3$ binding to CCR1 and CCR5 has no effect on neutrophil migration. Cell migration, in response to Lkn-l, was blocked by pertussis toxin (Ptx), a $G_o/G_i$ protein inhibitor, and U73122, a phospholipase C(PLC) inhibitor but not by protein kinase C inhibitor such as rottlerin, and Ro-31-8425. Taken together, our results demonstrate that Lkn-l transduces the chemotaxis signal through $G_o/G_i$ protein and PLC. This finding provides the molecular mechanism by which Lkn-l may contribute to neutrophil movement into the site of inflammation.

• Journal of Ginseng Research
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• v.32 no.3
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• pp.232-237
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• 2008

Cinnamoyl-CoA reductase (CCR, EC 1.2.1.44) catalyses the reduction of cinnamic acid CoA esters into their corresponding aldehydes, the first step of the phenylpropanoid pathway specially dedicated to monolignol biosynthesis. A cDNA clones encoding CCR have been isolated from Panax ginseng C.A. Meyer and its expression was investigated in response to abiotic stresses. The cDNA, designated PgCCR which is 865 nucleotides long and has an open reading frame of 590 bp with a deduced amino acid sequence of 176 residues. The PgCCR encoded protein possesses substantial homology with CCRs isolated and cloned from other sources; the highest identity (51.8%) was observed with CCR from Tomato (Lycopersicon esculentum). Under various stress conditions, expression patterns of the PgCCR were highly induced in adventitious and hairy roots by several abiotic stresses. These results indicated that PgCCR plays protective role against diverse environmental stresses.

• The Journal of the Convergence on Culture Technology
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• v.9 no.5
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• pp.91-98
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• 2023

This study is an exploratory research on smart healthcare services, specifically focusing on a multi-channel CCR based healthcare service system. The study examines the overview and operational principles of the service system, highlighting the significance of user communication and its role in the system's functionality. Furthermore, the study investigates the impact of service quality on user satisfaction and intention to continue using the service. To achieve this, a structural equation modeling(SEM) analysis was conducted with a sample of 188 users who owned and utilized healthcare devices and apps. The results indicate that service quality dimensions (reliability, responsiveness, empathy, assurance, and tangibility) all had a positive influence on user satisfaction. Additionally, user satisfaction was found to have a significant impact on intention to continue using the service. The findings of this study contribute to exploring the effectiveness and potential value of CCR-based smart healthcare services. It was also provided insights for the future development of smart healthcare systems that offer accurate health information and personalized services for individual health management and prevention.

• Journal of Integrative Natural Science
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• v.6 no.3
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• pp.163-169
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• 2013

The chemokine receptor CCR1 a GPCR super family protein contains seven transmembrane domains. It plays an important role in rheumatoid arthritis, organ transplant rejection, Alzheimer's disease and also causes inflammation. Because of its role in disease processes, antagonism of CCR1 became an attractive therapeutic target. In the current study, we have taken a novel series of recently reported CCR1 antagonist of 1-(4-Phenylpiperazin-1-yl_-2-(1H-Pyrazol-1-yl) ethanone derivatives and performed a HQSAR analysis. The model was developed with Atom (A) and bond (B) parameters and with different set of atom counts to improve the model. The results of HQSAR showed good predictive ability in terms of $r^2$ (0.904) and $q^2$ (0.590) with 0.710 as standard error of prediction and 0.344 as standard error of estimate. The contribution map depicted the atom contribution in inhibitory effect. Compound-14 which was reported to be a highly active compound showed positive atom contribution in three R groups ($R^3$. $R^{5a}$ and $R^{2b}$) in inhibitory effect, which could be the reason why this compound is highly active compound whereas, the lowest active compound-6 showed negative contribution to inhibitory effect.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.1218-1221
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• 2011

The development of the internet and information management has enabled new applications which include: Electronic medical record (EMR), intelligent transportation, environmental monitoring, etc. In this paper, we design and implement the Continuity Care Record(CCR) Data Stream management server that compiled with DSMS and DBMS in EMR system for processing, monitoring the incoming CCR data stream and storing the processed result with high-efficiency. The proposed system enables users not only to query stored CCR information from DBMS, but also enables to execute continue query for the real-time CCR Data Stream. By using of CCR Viewer Application users can view or update their personal health records even compare self health care records with standard health care records in order to monitor the healthy status, and the on line updating information would be minimized and medical error.