• 제목/요약/키워드: Body weight distribution

검색결과 482건 처리시간 0.034초

Prednisolone의 투여에 의한 마우스 비장의 Lymphocyte Subset의 변화 (The Effect on the Changes of Lymphocyte Subset in Spleen of Mouse by Prednisolone Administration)

  • 이경리;이병한;김진영;임좌진;정병헌
    • 한국임상수의학회지
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    • 제16권2호
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    • pp.454-462
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    • 1999
  • Corticosteroids have long been used for anti-inflammatory, anti-rheumatoid and other purposes in hospital. These effects may be due to inhibit immune reaction. So the animal given corticosteroids was more susceptible to infection because of immunosuppressive effect of corticosteroids. The purpose of this study was to investigate the effects of prednisolone on the lymphocyte subset in the spleen, immunoglobulin in serum, spleen weight, thymus weight and total WBC in peripheral blood. Mice were randomized into 3 groups. Each group has 24 mice. The small dosage group were given by 4 mg/kg/day of prednisolone for 4 days and the large dosage group were given by 8 mg/kg/day respectively. Prednisolone was suspended in saline and orally administered. Mice in control group were given saline alone. Eight mice in each group were sacrificed every week after administration of predisolone. The weight of thymus and spleen were mesured immediately. Lymphocytes were taken from spleen and these cells were analysed by flow cytometry. Also the concentration of total immunoglobulins in serum were assayed by enzyme-linked immunosorbant assay (ELISA). T cell, T-helper cell and T-cytotoxic cell were all significantly (P<0.05) decreased at 1 week after administration of predisolone and at 2 weeks they recovered similarly to that of control. Population of B cell showed various distribution. The concentration of total immunoglobulins in serum was not changed significantly. The weight ratio of spleen to body decreased significantly (P<0.05) during predisolone administration but increased at 1 week later, Eventually the weight ratio was recovered to that of control at 2 weeks. The weight ratio of thymus to body decreased significantly (P<0.05) by prednisolone and recovered gradually up to normal ratio 2 weeks later.

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Correlation between Abdominal Fat Distribution and Abdominal Temperature in Korean Premenopausal Obese Women

  • Song, Eun-Mo;Kim, Eun-Joo;Kim, Koh-Woon;Cho, Jae-Heung;Song, Mi-Yeon
    • 대한한의학회지
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    • 제34권2호
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    • pp.1-9
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    • 2013
  • Objectives: Considering that homeothermy is a major component of metabolic rate, body temperature might play a role in the pathophysiology of obesity. This study aimed to determine the relationship between abdominal fat distribution and abdominal temperature in Korean, premenopausal, obese women. Methods: Weight and height were measured in 26 premenopausal, obese women to calculate body mass index (BMI). Obesity was defined as a $BMI{\geq}25kg/m^2$. Waist circumference (WC) was also measured as well as abdominal fat by computed tomography (CT) and abdominal temperature by digital infrared thermographic imaging (DITI). Results: Visceral abdominal fat area was found to have a significant negative correlation with the temperature of Guanyuan (CV4, lower abdomen acupoint). We also found the visceral-subcutaneous fat ratio had a significant negative correlation with the temperature of CV4 and Right Tianshu (RST25, lateral navel acupoint). Only visceral fat and its ratio to subcutaneous fat had a significant correlation with abdominal temperature. Subcutaneous fat area and total fat area were not correlated with abdominal temperature. Conclusions: This study suggests that abdominal visceral fat has a significant negative correlation with abdominal temperature. Further study is needed to uncover the relationship between abdominal fat distribution and temperature regulation in obese individuals and to define the role of body temperature in the pathogenesis of obesity.

대학생의 체형인식과 비만도에 따른 체중조절 태도, 건강관련 생활습관 및 식행동 (College Students' Attitude toward Body Weight Control, Health-related Lifestyle and Dietary Behavior by Self-perception on Body Image and Obesity Index)

  • 진정희;장경자
    • 한국식품영양과학회지
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    • 제34권10호
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    • pp.1559-1565
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    • 2005
  • 인터넷을 통해 체중조절에 관한 영양교육을 수강한 전국 규모의 대학생 871명(남 330명, 여 541명)을 대상으로 체형 인식과 비만도에 따른 체중조절 태도, 건강관련 생활습관 및 식행동에 대해 살펴보고자 인터넷상에서 설문조사를 실시한 결과는 다음과 같다. 조사대상자들의 남녀 평균 신장은 한국인 체위기준치와 비교하여 남녀 모두 기준치와 거의 같았으나 체중은 기준치와 비교할 때 남학생이 약간 높았고 여학생은 기준치와 거의 같았다. 비만도에 따른 체중군의 분포는 남녀 학생간에 유의적 차이를 보여서 남학생은 정상체중군이거나 과체중군이 많은 반면에 여학생은 정상체중군이거나 저체중군이 많은 것으로 나타났다. 체형 인식, 체중 조절 필요성과 체증변화 노력 유무에 남녀 학생간에 유의적 차이를 보여서 여학생이 자신을 뚱뚱하다고 인식하는 비율이 매우 높고 외모에 치중하여 체중변화에 대한 노력을 더 많이 하는 것으로 나타났다. 건강관련 생활습관 중 운동시간, 음주정도, 흡연정도에서 비만도에 따른 체중군간에 유의적 차이를 보여서 저체중 이하나 과체중 이상의 학생군은 정상체중 학생군에 비하여 운동을 하지 않는 경우가 많은 것으로 나타났고, 과체중 이상의 학생군에서 평소 음주량이 많았고, 흡연율도 높은 것으로 나타났다. 체중조절 방법에 대한 인식으로 다이어트 전문회사의 체중관리 프로그램 참여를 가장 긍정적으로 인식하였고, 병원의 비만클리닉 이용에 대해서는 체중군간에 유의적 차이를 보였다. 이상의 결과로 볼 때 대학생 시기에 잘못된 체형인식, 생활습관이나 식행동으로 인한 건강문제를 인지하고 대학생에게 올바른 체중조절 태도, 건강관련 생활습관 및 식행동을 교육할 수 있는 제도적 노력이 요구된다.고,-77$^{\circ}C$ 저장온도를 제외하고는 모두 유의성 있는 변화량을 나타내었다(p < 0.05). 실험군의 압착육즙 내 mitochondrial malate dehydrogenase의 활성은 10분간 흡광도 변화량을 조사함으로써 계산되었다. 등심을 제외한 모든 부위에서 호소반응개시 3분 후에 -4$^{\circ}C$에서 동결우육을 제외하고 동결우육의 효소 활성이 떨어지는 것을 확인할 수 있었고, 5분 반응 후에는 그 효소의 활성을 발견할 수 없었다. 냉장우육은 12분까지 활성을 측정할 수 있었다. 15일간 냉장우육 및 냉동우육을 저장 온도에 따라 저장하면서 그 활성을 측정하였는데, 저장 기간이 길어져도 그 효소활성의 차이는 유의적으로 변화하지 않고, 모든 실험군(사태, 등심, 양지, 우둔 부위 )에서 유의적으로 유사한 활성을 유지하였다(p < 0.05). 따라서 본 연구 결과로부터 mitochondrial malate dehydrogenase의 활성을 이용하여 냉장우육과 냉동우육 유무를 판별하는데 유효한 지표로 사용 가능한 것으로 사료되었다. 나타냈고 시료투여군인 SOL 및 SOH는 CMT보다 우수하지는 않았으나 약 $35\∼42\%$ 정도의 궤양억제율을 나타냈다. 이상의 실험결과에서 지유의 항위염 및 항궤양효과는 항산화물질에 의한 결과로 판단되어지며, 앞으로 위염 및 위궤양 개선을 위한 건강 기능성 식품으로 개발이 기대된다$ (0.5000) and $TF^{F2}$ (0.4950) 대립유전자가 가장 높은 빈도를 나타내었고 $D^{cgm(f)}$ (0.0196),

건강상태(健康狀態)와 생활양식(生活樣式)(건강습관(健康習慣))과의 관계(關係) (Relationship between Physical Health Status and Life style(Health Practices))

  • 최인숙;노병의;박영수
    • 한국학교ㆍ지역보건교육학회지
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    • 제3권
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    • pp.111-140
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    • 2002
  • This study was conducted from April 1 through April 30, 2002 in order to figure out the relationship between physical health status and life style and the factors influencing physical health. Subjects were selected from among the residents older than 20 years old by probability scheme of one out of 2000. Three thousand people were interviewed by questionnaires, and 2,742(91.4%) respondents were used for analysis, and the results are as follows: 1. Ridit(Relatives to an identified distribution it) of category one by sex was 0.26 in man, and 0.25 in woman. Ridit of category two was 0.57 in man and 0.53 in woman, those of category three was 0.72 in man and 0.65 in woman. That of category four was 0.86 in man and 0.85 in woman, that of category five was 0.95 in man and 0.97 in woman, and that of category six was 0.98 in man and 0.99 in woman. The ridits and health related categories by sex were r=.954 in man and r=.966 in woman(p<0.01) 2. Ridits of healthy behavior 2-1. The ridit of males who slept for less than 6 hrs was 0.71, that of those who slept for $7{\sim}8$ hrs was 0.24, and that of those who slept for more than 9 hours was 0.96. The ridit of females who slept for less than 6 was 0.80, that of those who slept for $7{\sim}8$ hrs was 0.32, and that of those who slept for more than 9 hrs was 0.97. 2-2. The ridit of male, who ate breakfast everyday was 0.30, that of those who ate one to four breakfast per week was 0.87, and that of those who never ate breakfasts was 0.96. The ridit of females who ate breakfast everyday was 0.32, that of those who ate breakfast one to four times a week was 0.75, and that of those who never ate breakfast was 0.99. 2-3. The ridit of males whose body weights were 10% lower than normal body weight was 0.45, that of those with $5{\sim}9.9%$ less than normal body weight was 0.28, that of those with ${\pm}4.9%$ of normal body weight was 0.12, that of those whose body weights were $5{\sim}9.9%$ heavier than normal was 0.40, that of those whose body weights were $10{\sim}19.9%$ heavier than normal was 0.74, that of those with $20{\sim}29.9%$ heavier than normal body weights was 0.78 and that of those with 30% heavier than normal body weight was 0.87. That of females with 10% less than normal body weight was 0.53, that of those with $5{\sim}99%$ less than normal body weight was 0.32, that of 4.9% those with ${\pm}f$ normal body weight was 0.14, that of those with 5.0 to 9.9% heavier body weights was 0.43, that of those with 10 to 19.9% heavier body weight was 0.65, that of those with $20{\sim}29.9%$ heavier body weight was 0.94 and that of those with more than 30% of normal body weight was 0.94. 2-4. The ridit of males who exercised everyday was 0.11, that of those who exercised three to four times a week was 0.25, that of those exercising once or twice a week was 0.48, and that of those who never exercised was 0.80. The ridit of females exercising everyday was 0.08, that of those exercising three to four times a week was 0.21, that of those exercising one to two times was 0.35 and that of those who never exercised was 0.72. 2-5. The ridit of males who did not drink at all was 0.14, that of those who drank one or two cups of hard liquor(Soju) was 0.39, that of those who drank a half bottle of Soju was 0.56, that of those who darnk a bottle of Soju was 0.73 and that of those who drank two bottles of Soju was 0.96. The ridit of females who did not drink at all was 0.30, that of those who drank one or two cups of Soju was 0.70, that of those who drank a half bottle of Soju was 0.84, that of those who drank a bottle of Soju was 0.97 and that of those who drank more than two bottles of Soju was 0.99. 2-6 The ridit of males who did not smoke was 0.20, that of those who smoked one or two cigarettes was 0.44, that of those who smoked about ten cigarettes was 0.58, and that of those who smoked more than a pack of cigarettes was 0.85. The ridit of females who did not smoke at all was 0.90, that of those who smokes one or two cigarettes was 0.91, that of those who smoked about the cigarettes was 0.93 and that of those who smoked more than a pack of cigarettes was 0.96 3. The ridit of males who had healthy behavior in six categories was 0.43 and the average age of them was 45, that of those who had healthy behavior in five categories was 0.47 and the average age was 45, that of those who had healthy behavior in three categories was 0.50 and the average age was 43, that of those who had heathy behavior in two categories was 0.60 and the average age was 40, that of those who had healthy behavior in one category was 0.68 and the average age was 38, and that of those who did not have healthy behavior at all in six categories was 0.79 and the average age was 41. The ridit of females who had heathy behavior in six categories was 0.38 and the average age was 45, that of those who had healthy behavior in five categories was 0.40 and the average age was 44, that of those who had healthy behavior in four categories was 0.46 and the average age was 43, that of those who had healthy behavior in three categories was 0.52 and the average age was 44, that of those who had healthy behavior in two categories was 0.57 and the average age was 41, that of those who the healthy behavior in one category was 0.62 and the average age was 40, and that those who did not have healthy behavior in six categories was 0.79 and the average age was 43. 4. The health statues of the persons who the healthy behavior were better than those who did not have healthy behavior. If the people have healthy behavior in young age and they have healthy education continuously, they can live healthier lives.

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흰쥐에서 Divalent Metal Transporter 1의 조직내 분포와 Iron에 의한 조절 (Tissue Distribution of Divalent Metal Transporter 1 and Regulation by Dietary Iron in Rats)

  • 최재혁;박정덕
    • Environmental Analysis Health and Toxicology
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    • 제19권4호
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    • pp.359-366
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    • 2004
  • Iron (Fe) is an essential metal in biological processes, which maintains a homeostasis in the human body. Divalent metal transporter 1 (DMT1) has been known as an iron transporting membrane protein, which is involved in the uptake Fe at the apical portion of intestinal epithelium, and may transport Fe across the membrane of acidified endosome in peripheral tissues. In this study, we studied the tissue distribution of DMT1 in the Fe supplemented (FeS) diet fed rats, and the regulation of DMT1 expression by depleting body Fe. Sprague-Dawley rats were divided into two groups, and fed FeS (120 mg Fe/kg) diet or Fe deficient (FeD, 2∼6 mg Fe/kg) diet for 4 weeks. The evaluation of body Fe status was monitored by measuring sFe, UIBC and tissue Fe concentration. Additionally, DMT1 mRNA levels were analyzed in the peripheral tissues by using the quantitative real time RT-PCR method. In the FeS diet fed rats, the tissue Fe was maintained at a relatively high level, and DMT1 was eventually expressed in all tissues studied. DMT1 was highly expressed in the testis, kidney and spleen, while a moderate levels of DMT1 expression was detected in the brain, liver and heart. In the digestive system, the highest level of DMT1 was found in the duodenum. Feeding the FeD diet caused a reduced body weight gain and depletion of body Fe with finding of decreased sFe, increased UIBC and decreased tissue Fe concentration. The depletion of body Fe upregulated DMT1 expression in the peripheral tissue. The expression of DMT1 was very sensitive to the body Fe depletion in the small intestine, especially in the duodenum, showing dramatically higher levels in the FeD rats than those of the FeS group. In the FeD diet fed animals, the expression of DMT1 was low significantly in other tissues compared with the duodenum. The expression of DMT1, however, was 60∼120% higher in the testis, kidney and spleen, and 30∼50% higher in the lung, liver and heart, compared to the FeS diet fed rats. In summary, DMT1 expression was ubiquitous in mammalian tissue, and the level of expression was the organ-dependent. The expression of DMT1 in peripheral tissues was upregulated by depletion of body Fe. Duodenum was the most sensitive tissue among organs studied during Fe depletion, and expressed the greatest level of DMT1, while other tissues were less higher than in duodenum. This study supports that DMT1 plays a role in maintaining the body Fe level through intestinal uptake as well as homeostasis of Fe in the peripheral tissue.

고려인삼과 미국삼의 품질요인별 수삼 및 홍삼등급 비교 (Comparison of Grade of Raw and Red Ginseng on each Factor of Quality in Korean and American Ginseng)

  • 정찬문;신주식
    • 한국약용작물학회지
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    • 제14권4호
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    • pp.229-233
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    • 2006
  • 고려인삼과 미국삼에 있어 원료수삼의 품질 외적요인과 홍삼품질과의 관계를 조사하여 종간특성을 비교하였다. 원료수삼의 편급과 등급을 결정하는 품질요인은 체형계수, 동장 그리고 근중을 적용하였으며 이들 요인과 홍삼 품질관계를 구명하였다. 1. 편급의 분포는 고려인삼의 경우 중편과 대편급이 많았으나 미국삼은 중편과 소편급이 많았으며 미국삼은 고려인삼에 비해 동장이 짧고 동직경이 굵고 부정형 지근이 많았다. 2. 원료삼 품질은 고려인삼이 미국삼에 비하여 양호하였고 홍삼품질은 고려인삼이 지삼 이상의 고급홍삼이 많았으나 미국삼은 양삼과 같이 저급홍삼이 많았다. 3. 원료수삼 품질요인중 중편삼과 대편삼의 경우 고려인삼은 체형계수 0.5 이하였으나 미국삼은 0.5를 상회하여 미국삼은 홍삼품질에 적합하지 않았다. 4. 고려인삼과 미국삼 모두 품질요인으로 동장과 근중은 홍삼품질과의 관계에서 비슷한 경향이나 체형계수가 특히 홍삼의 품질을 좌우하는 요인이었다. 5. 따라서 고려인삼과 미국삼 모두 원료삼과 홍삼품질 향상을 위해 근중, 체형계수 그리고 동장의 조정이 요망되었다.

태음인 비만아를 위한 체중조절 프로그램의 실시효과 (The Effect of Education Program on Weight Control in Taeumin Childhood Obesity)

  • 유정희;송일병;이의주;백상용;고병희;이향련
    • 대한한의학회지
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    • 제26권1호
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    • pp.103-114
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    • 2005
  • Objective; Childhood obesity has become one of the most common health problems facing children in the world. Although a number of regimens have been developed and distributed for the treatment of adult obesity, few studies have focused on therapeutic programs for obese children. The objective of this study was to develop and measure the effects of Taeumin childhood obesity by a sasang constitution­based education program. Methods ; A total of 14$(\%RBW\geq20)$ among 18 taeumin with childhood obesity from June to August 2003 participated in the constitution-based education program. It was designed to examine the effects of a constitution-based education program through anthropometric measurements, body composition indicates, biochemical indicates and serum level of taeumin childhood obesity. Results; The results of this study were as follows: 1. The anthropometric measurement of subscapular skinfold thickness was reduced after 4 weeks of the constitution-based education program. 2. The body composition indicates reduction in degree of obesity, percent body fat, and fat distribution. The other side increased in height, total body water, soft lean mass, and lean body mass. 3. For biochemical indicates, HDL-cholesterol was increased significantly after 4 weeks of the constitution-based education program. The other side decreased in AST and ALT. 4. There was a significant reduction in BMI and $\%RBW$ after the constitution-based education program. Conclusion : A constitution-based education program for weight control results in reduced degree of obesity among taeumin children.

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Fenitrothion의 생체내 분포 및 잔류성에 관하여 (Distribution and Persistence of Fenitrothion in Rats)

  • 이상기;유영찬;정규혁
    • 한국환경보건학회지
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    • 제23권1호
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    • pp.8-13
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    • 1997
  • Distribution and persistence of fenitrothion in rats were studied following oral administration of a single dose 300 mg/kg of body weight. Residue of the parent compound was analyzed in blood, liver, kidney, brain, lung and heart 2, 4, 6, 8 hours and 1, 2, 3, 5, 7 days after oral administration. The maximum concentration of fenitrothion appeared in the blood, kidney, heart on the 2 hour and liver, brain, lung on the 4 hour. Residues of the parent compound in kidney were much higher and persistent than other tissues and the pesticide was not detected on the 7th day. Recoveries were ranged from 83.0(lung, $1 \mu g/g$) to 97.5%(blood, $1.5 \mu g/ml$).

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운동이 복부형 비만여성의 혈청지질에 미치는 영향 (Effect of Exercise on Serum Lipids in Abdominal Obese Women)

  • 전형주;이재학
    • 한국식품영양학회지
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    • 제16권3호
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    • pp.192-196
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    • 2003
  • 허리 둔부 둘레비가 0.85이상인 여성을 복부 비만으로 측정하고 8주간 계속해서 50분씩 달리기를 시행하였다 5Km의 실외 달리기 트랙을 50분간 강약 조절로 달리게 하였고, 운동을 시행한 후 체성분 변화에 대한 결과를 분석하였다. 본 연구의 결과, 8주간 운동에 의해 변화된 총 cholesterol이 LDL-C과 양의 상관관계를 보였다. (P<0.001), 허리 둔부 둘레비(WHR)는 총 cholesterol과 triglyceride의 변화량과 양의 상관관계를 보였으며(P<0.05) 허리 둔부 둘레비는 혈청 지질의 수준에 영향을 주었다. 또한 운동에 의하여 BMI와 체지방량은 유의적인 감소를 하였고 혈청지질 중 triglyceride는 역시 유의적인 감소를 보였다. 따라서 운동은 복부비만 여성에게 혈청지질 농도를 변화시켜 고지혈증이나 성인병의 유발을 감소시킬 것으로 사료된다. 한편 HDL-C과 LDL-C은 유의적인 변화를 보이지 않았으므로 장기간 운동에 의한 신체의 영향을 지속적으로 연구하는 일이 요구된다고 할 수 있다. 운동전, 혈청지질 간의 상관관계에서 총 cholesterol은 triglyceride, LDL-C과 양의 상관관계를 보였으며 운동 후 변화량을 비교한 상관관계에서도 총 cholesterol과 LDL-C은 양의 상관관계를 보였다. 허리 둔부 둘레비도 총 cholesterol과 triglyceride에 유의적인 상관성을 보여 체지방량 감소에 의하여 체형이 변화될 수 있는 가능성을 시사하였다. 복부비만 여성을 대상으로 실시한 운동은 혈청지질 농도 개선에 전반적인 효과가 있는 것으로 나타났으나 운동이 LDL-C과 HDL-C에 미치는 영향을 구체적으로 연구하기 위하여 좀 더 장기적인 연구가 지속되어야 하며, 앞으로 허리 둔부 둘레비와 심혈관 질환과의 상관성도 깊게 연구되어야 할 필요가 있다고 사료된다.

윤충류 생체량 계산과 적용에 관한 고찰 및 제언: Polyarthra의 체장 분포를 이용한 길이-무게 관계식 및 생체량 비교 분석 (Calculation and Applicability of Rotifers Biomass (Polyarthra spp.) based on Length-Weight Relationship and Spatial Distribution of Body Length)

  • 오혜지;서동환;최문정;정현기;김현우;오종민;장광현
    • 생태와환경
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    • 제51권3호
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    • pp.205-211
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    • 2018
  • 본 연구에서는 다른 환경에서 채집된 윤충류 개체의 체장을 측정하고 기존에 제시된 윤충류 생체량 측정 방법에 적용하여, 생체량 값의 분포 검증 및 비교를 실시하였다. 이를 바탕으로 적절한 윤충류 생체량 계산 방법에 대해 고찰하고, 체장 측정 없이 종별 생체량의 대푯값을 사용하는 것이 가능한지에 대한 여부를 판단했다. 검증을 위한 대상으로 국내외적으로 우점하고 단순한 형태를 가지는 Polyarthra 속을 선정, 한강, 낙동강 및 팔당호에서 시료를 채집, 분석하였다. 지점에 따른 Polyarthra spp. 개체의 체장은 통계적으로 유의한 차이를 나타내어, 지점별 체장의 차이가 생체량 대푯값을 이용하는데 발생하는 오차의 원인이 될 수 있는 것으로 분석되었다. 보다 정확한 생체량 계산을 위해 윤충류 개체의 체장 측정은 필수적인 것으로 판단되며, 생체량 계산 시 오차가 5% 이하일 확률을 99% 이상으로 높이기 위해서는 44개체 이상의 체장을 측정해야 하는 것으로 나타났다. 측정한 체장을 이용한 생체량 계산에는 EPA 계산식 대비 McCauley (1984)의 계산식을 사용하는 것이 보다 적합할 것으로 보이지만, 기술 검증이 어려운 항목이기 때문에 향후 본 조사에서 보여진 지점 간 변이 이외에 윤충류의 복잡한 형태 및 다양한 부속지의 변화 등을 고려하여 다양한 종을 대상으로 한 추가적인 분석이 필요할 것으로 판단된다.