• Title/Summary/Keyword: Blood lactate concentration

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A Study on the Changes of Blood Mineral and Enzyme Activity During Growth Period of Velvet Antler in Korean Spotted Deer(Cervus Nippon) (꽃사슴의 녹용 성장기간 중 혈액 내 미네랄 및 효소활성 변화에 관한 연구)

  • Kim, M.H.;Moon, S.H.;Lee, C.H.;Jeon, B.T.
    • Journal of Animal Science and Technology
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    • v.45 no.6
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    • pp.1031-1038
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    • 2003
  • This study was aimed at investigating the change of blood mineral and enzyme activity during growth period of velvet antler in Korean spotted deer. Samples of blood, obtained from the jugular vein of twenty-five deer(4 to 6 year-old males), were taken in 10 days interval from just after casting to 50 days. Deer were randomly selected from the farm, and samples were analyzed for blood parameters like mineral concentration and enzyme activities. No significant differences found in calcium and phosphorus concentration in blood whereas sodium, potassium and chloride concentration were significantly changed with antler growth. There were no significant differences in alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, $\gamma$-glutamyl transferase and lactate dehydrogenase during growth of antler, but alkaline phosphatase concentration was increased with growth of antler, and the highest concentration was obtained on the 50 days after casting. Creatine kinase and lactate dehydrogenase activities for the deer tested in this experiment were higher than those of other animals.

The Effect of Regular Exercise on the Level of Blood Lactate and LDH Production in College Women (운동습관이 혈액중 젖산농도 및 LDH 생성에 미치는 영향)

  • 남정혜
    • The Korean Journal of Food And Nutrition
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    • v.14 no.4
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    • pp.355-359
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    • 2001
  • The purpose of this study was to compare the level of blood glucose and lactate and also plasma LDH production of college women in relation to exercise. College female student which majored athletics (E, exercise group, n=43) were recruited and compared with college women (Control group, n=60). Anthropometric measurements, triceps skinfold thickness were measured of two groups. And body fat mass and waist and hip circumferences were measured and the concentrations of plasma glucose, lactic acid and lactic acid dehydrogenase (LDH) were also assayed. Average height and weight of E group were slightly higher than that of control group. but there is no difference in body mass index (BMI) and waist hip ratio (WHR) between two groups. The percentage of body fat and body fat mass(kg) in E group was slightly lower than that of control group. Plasma glucose and LDH levels of E group were higher than those of control group, and plasma lactic acid concentration was significantly increased.

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Effects of the Zizyphus jujuba Seed Extract on the Lipid Components in Hyperlipidemic Rats

  • Kim, Han-Soo
    • Preventive Nutrition and Food Science
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    • v.7 no.1
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    • pp.72-77
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    • 2002
  • The purpose of this study was designed to observe the effects of Zizyphus jujuba seed extract on the concentrations of the lipids and blood glucose in the S.D. rats fed the experimental diets for 4 weeks. Concentrations of total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free-cholesterol, cholesteryl ester, triglyceride (TG), phospholipid (PL) and blood glucose in serum were significantly higher in the cholesterol administration groups (group 2 (cholesterol+water), group 3 (cholesterol+Zizyphus jujuba seed extract)) than those in the control group (group 1, basal diet+water). But the concentrations of total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free-cholesterol, cholesteryl ester, TG, PL and blood glucose in serum ware remarkably lower in the group 3 than those in the group 2. In the ratio of HIDL-cholesterol concentration to total cholesterol and HDL-cholesterol concentration, Zizyphus jujuba seed extract administration group was higher percentage than in the group 2. The activities of aspartate aminotransferase (AST), alanine amino-transferase (ALT), lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) in serum were rather lower in the Zizyphus jujuba seed extract administration group (group 3) than in the cholesterol diet group (group 2). From the above research, Zizyphus jujuba seeds were effective on the improvement of the blood glucose, lipid compositions in serum of dietary hyperlipidemic rats. And particularly, Zizyphus jujuba seeds were more effective as a therapeutic regimen for the control of metabolic derangements in adult disease.

The Effect of Kinesio Taping and Icing on Blood Lactate Density and Heart Rate Recover Pace After Shuttle Run Test (키네시오 테이핑과 아이싱 처치가 셔틀런 테스트 후 혈중 젖산 농도 및 심박수의 회복속도에 미치는 영향)

  • Heo, Seung-Jae;Kim, Yong-Jin
    • Journal of Digital Convergence
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    • v.14 no.6
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    • pp.431-438
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    • 2016
  • This study will be targeting 21-24 years old college students majoring in physical education. This study covers the effect of kinesiology taping and icing treatment on the recovery rate of blood lactate concentration, and cardiovascular function so that it can provide the basic data for improving physical performance. As a result of this study, Kinesio taping and icing aid the recovery rate of the maximum load of lactic acid recovery rate and 30 minutes after exercise heart rate after exercise, but increased, after 15 minutes, immediately after exercise heart rate, exercise lactate and heart rate, and 30 minutes after exercise lactate showed no difference. In conclusion, Kinesio taping and icing treatment, reduce pain and fatigue but it is not satisfactory. Further study, applying a more accurate and technical form of exercise programs needs to continuously research the effects of Kinesio taping and icing treatment

A New Shock Index for Predicting Survival of Rats with Hemorrhagic Shock Using Perfusion and Lactate Concentration Ratio (흰쥐의 출혈성 쇼크에서 관류와 젖산 농도 비를 이용한 새로운 생존 예측 지표 개발)

  • Choi, Jae-Lim;Nam, Ki-Chang;Kwon, Min-Kyung;Jang, Kyung-Hwan;Kim, Deok-Won
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.48 no.4
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    • pp.1-9
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    • 2011
  • Hemorrhagic shock is a clinically widespread syndrome characterized by inadequate oxygenation and supply. It is important to diagnose hemorrhagic shock in its early stage for improving treatment effects and survival rate. However, an accurate diagnosis and treatment could be delayed in the early stage of hemorrhagic shock by evaluating only vital signs such as heart rate and blood pressure. There have been many studies for the early diagnosis of hemorrhagic shock, reporting that lactate concentration and perfusion were useful variables for tissue hypoxia and metabolic acidosis. In this study, we measured both perfusion using a laser Doppler flowmeter and lactate concentration from the volume controlled hemorrhagic shock using rats. We also proposed a new shock index which was calculated by dividing lactate concentration by perfusion for early diagnosis. As a result of the survival prediction by the proposed index with the receiver operating characteristic curve method, the sensitivity, specificity, and accuracy of survival were 90.0, 96.7 and 94.0%, respectively. The proposed index showed the fastest significant difference among the other parameters such as blood pressure and heart rate. It could offer early diagnosis and effective treatment for human hemorrhagic shock if it is applicable to humans.

Application of a standardized exercise test by measuring serum lactate concentration in Thoroughbred racehorses (더러브렛 경주마에서 혈청 젖산농도 측정에 의한 표준운동능력검사의 적용)

  • Mun, Kyu-whan;Kim, Joon-gyu;Kim, Byung-sun;Um, Young-ho;Yang, Il-suk
    • Korean Journal of Veterinary Research
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    • v.39 no.6
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    • pp.1081-1090
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    • 1999
  • To establish the protocol of a standardized exercise test for evaluating exercise intolerance and degree of fitness in Thoroughbred racehorses, we examined serum lactate concentrations related to exercise intensities using the high speed treadmill. Twelve clinically healthy Thoroughbred racehorses with or without previous training or racing history were assigned to two gorups, fit and unfit group, respectively. The protocol used for the standardized exercise test was consisted of two stages : stage of warm-up and that of acceleration. During the warm-up, the horses exercised 5 min at 1.8m/s and 3 min 3.4m/s without inclination. At the acceleration stage, exercise test was performed at 10% slope and the speed was increased from the initial 5m/s to the maximal speed which each tested horse could keep up with. The speed was increased with incremental steps of 1 m/s every minute. During the last 15 sec of each step, blood samples were collected for serum lactate determination. $V_{max}$(maximal treadmill speed which tested horses could keep up with) of the fit group ($10.93{\pm}0.33m/s$, mean${\pm}$SE, n = 6) was higher than that of the unfit group ($9.52{\pm}0.23m/s$, mean${\pm}$SE, n = 6). Serum lactate concentrations increased exponentially according to exercise intensities. $V_{La4}$(speed producing a serum lactate concentration of 4mmol/l) of the fit group, $6.45{\pm}0.26m/s$, was higher than that of the unfit group, $5.45{\pm}0.23m/s$. $La_{peak}$(peak plasma lactate concentration during the exercise test) was lower in the fit group ($20.34{\pm}1.62mmol/l$ at 1 min after maximal intensity exercise) than in the unfit group ($24.78{\pm}1.09mmol/l$ at 2 min after maximal exercise step). $t_{50%}$(time required for the recovery of lactate concentration to be one-half of $La_{peak}$ after maximal exercise) of the unfit group and the fit group were 40.0 and 18.0 min, respectively. Therefore, the protocol of the incremental standardized exercise test utilized in this study seems to be reliable for the assessment of fitness and exercise intolerance for the Thoroughbred racehorses.

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A study on the short-term effects of Ginseng Radix Alba extract on muscle fatigue and blood components of the rats. (생쥐의 근피로(筋疲勞) 및 혈액성분(血液成分)에 대한 단기(短期) 인삼투여(人蔘投與)의 효과(效果)에 관한 연구(硏究))

  • Lee, Jin-Moo;Lee, Chang-Hoon;Cho, Jung-Hoon;Jang, Jun-Bock;Kim, Yong-Seok;Lee, Kyung-Sub;Hwang, Jae-Ho
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.2
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    • pp.97-106
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    • 2007
  • Purpose: This study was conducted to investigate the short-term effects of Ginseng Radix Alba extract solution on muscle fatigue and concentration of blood components especially in glucose and lactate dehydrogenase of the rats. Methods: The 4~6-week-old ICR rats are used in the study, and we administered the extract solution of Ginseng Radix Alba concentration of 1, 10, 100mg/0.3ml to each rats and water to another rats(control group) once a day for each 30 and 60 days. After 30 and 60 days. we measured the persistent time of swimming exercise test and the results of grip strength test. And we also examined the plasma concentration of glucose, and lactate dehydrogenase. Results: In swimming exercise test, the swimming time of the 1, 10, 100mg/0.3ml groups for 30 days and the 100mg/0.3ml group for 60 days significantly increased than control group. and we found that as the concentration increased, the swimming time was also increased for 30 and 60 days experiment. And in grip strength test, the grip strength of the 1, 10, 100mg/0.3ml groups for 30 days and the 10mg/0.3ml group for 60 days significantly increased than control group. and we found that as the concentration increased, the grip strength was also increased for 30 days experiment. Plasma concentration of lactate dehydrogenase was significantly increased in the 10mg/0.3ml group for 60 days than control group. And there was no significant differences between the control and the treatment group in the plasma concentration of glucose. Conclusion: This study show that Ginseng Radix Alba can increase the muscle strength and antifatigue effect.

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Effects of clove oil on haematology and blood chemistry in crusian carp (Carassius auratus) (Clove Oil의 붕어(carassius auratus) 혈액 및 혈액화학치에 대한 영향)

  • Kho, Kyoung-Nam;Jung, Tae-Sung;Heo, Gang-Joon
    • Korean Journal of Veterinary Research
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    • v.47 no.4
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    • pp.483-488
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    • 2007
  • To determine the effects of anesthesia to clove oil on the secondary stress indices, changes in haematological and blood chemistry were monitored in healthy crucian carps (Carassius auratus). 24 fishes were divided into three groups, and blood was collected before anaesthesia (control group), immediately after anaesthesia at a concentration of 30 mg/l clove oil (anesthetized group), and 24 h after anaesthesia (recovered group). The anesthesia to clove oil significantly increased glucose in anaesthetized group, and constantly decreased lactate dehydrogenase in anaesthetized group and recovered group. However, clove oil had not effect on other biochemical indices. These results suggests that the anesthetic use of clove oil at a concentration of 30 mg/l does not cause irreversible damage in carp.

Chloride and lactate as prognostic indicators of calf diarrhea from eighty-nine cases

  • Gencay Ekinci;Emre Tufekci;Youssouf Cisse;Ilknur Karaca Bekdik;Ali Cesur Onmaz;Oznur Aslan;Vehbi Gunes;Mehmet Citil;Ihsan Keles
    • Journal of Veterinary Science
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    • v.25 no.3
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    • pp.38.1-38.16
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    • 2024
  • Importance: Deaths due to neonatal calf diarrhea are still one of the most critical problems of cattle breeding worldwide. Determining the parameters that can predict diarrhea-related deaths in calves is especially important in terms of prognosis and treatment strategies for the disease. Objective: The primary purpose of this study was to determine mortality rates and durations, survival status, and predictive prognosis parameters based on vital signs, hematology, and blood gas analyses in neonatal diarrheic calves. Methods: The hospital automation system retrospectively obtained data from 89 neonatal diarrheic calves. Results: It was found that 42.7% (38/89) of the calves brought with the complaint of diarrhea died during hospitalization or after discharge. Short-term and long-term fatalities were a median of 9.25 hours and a median of 51.50 hours, respectively. When the data obtained from this study is evaluated, body temperature (℃), pH, base excess (mmol/L), and sodium bicarbonate (mmol/L) parameters were found to be lower, and hemoglobin (g/dL), hematocrit (%), lactate (mmol/L), chloride (mmol/L), sodium (mmol/L) and anion gap (mmol/L) parameters were found to be higher in dead calves compared to survivors. Accordingly, hypothermia, metabolic acidosis, and dehydration findings were seen as clinical conditions that should be considered. Logistic regression analysis showed that lactate (odds ratio, 1.429) and CI- (odds ratio, 1.232) concentration were significant risk factors associated with death in calves with diarrhea. Conclusions and Relevance: According to the findings obtained from this study, the determination of lactate and Cl- levels can be used as an adjunctive supplementary test in distinguishing calves with diarrhea with a good prognosis.

Evaluation of Interfering Substances in Routine Chemistry Tests Using Toshiba TBA-C8000 Chemistry Analyzer

  • Park, Jum Gi;Joo, Kyeng Woong
    • Korean Journal of Clinical Laboratory Science
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    • v.43 no.1
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    • pp.6-11
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    • 2011
  • In clinical chemistry tests, the interfering substances such as hemoglobin, lipid, bilirubin, and drugs, etc. can cause the changes of test results performed by spectrophotometrical methods. We evaluated the effects of interfering substances on the test results by adding interfering substances on the samples in the 19 kinds of clinical chemistry tests such as aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, total protein, albumin, glucose, total cholesterol, total bilirubin, triglyceride, uric acid, calcium, inorganic phosphours, high density lipoprotein cholesterol, low density lipoprotein cholesterol, creatinine, blood urea nitrogen, and C-reactive protein using newly implemented automatic chemical analyzer Toshiba TBA-C8000 under the direction of CLSI EP07-A guideline. Hemolytic samples show increased concentration of total protein, aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase and reduced concentration of total bilirubin, alkaline phosphatase by interfering effect. Hyperlipemic samples show increased concentration of total protein and alkaline phosphatase and reduced concentration of low density lipoprotein cholesterol. The samples with conjugated bilirubinemia show increased concentration of inorganic phosphours, otherwise the samples with unconjugated bilirubinemia show no interference or allowable range in the test result.

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