• Journal of Korean Biological Nursing Science
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• 제16권4호
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• pp.300-308
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• 2014

Purpose: The purpose of this study was to analyze the effects of eucalyptus aroma therapy on relieving allergic rhinitis symptoms, improving learning ability and quality of life among university students. Methods: In this study, a non-equivalent control group repeated measured design was applied. Participants included 48 students (24 participants in the experiment and 24 participants in the control group) who were diagnosed with allergic rhinitis. Data were collected on 3 occasions, before eucalyptus aroma application, 4 weeks after the application, and 8 weeks after the application. Collected data were analyzed using ${\chi}^2$-test, Fishers exact test, independent t-test, repeated measured ANCOVA and paired t-test with SPSS 21.0. Results: There were significant differences in allergic symptoms (F=6.926, p=.002) and quality of life (F=3.793, p=.026) according to the time periods after aroma application. Conclusion: Eucalyptus aroma therapy is effective in reducing the symptoms of allergic rhinitis and enhancing the quality of life of university students. It is recommended that eucalyptus aroma therapy be used for university students with allergic rhinitis to reduce their symptoms, and it is recommended that the application of the therapy be extended over 4 weeks.

• Journal of Korean Biological Nursing Science
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• 제22권2호
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• pp.127-138
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• 2020

Purpose: The purpose of this study was to examine the effect of Seogeum therapy on nasal eosinophil, nasal symptoms, and rhinitisrelated quality of life in college students with allergic rhinitis. Methods: A nonequivalent control group pre-post test design was used. There were 26 subjects in the experimental group and 26 subjects in the control group. The experimental group received Seogeum therapy on both hands 12 times for three weeks. The collected data were analyzed with SPSS 21.0 version using χ²-tests, Fisher's exact test, independent t-test, and repeated measure of the ANOVA Results: After three weeks the positive rate of nasal eosinophils (p= .048) significantly decreased in the experimental group than in the control group. The experimental group demonstrated significantly lower total nasal symptom score (p= .032) and higher rhinitis-related quality of life (p< .001) compared to the control group. Conclusion: These findings showed that Seogeum therapy is effective as well as beneficial in relieving nasal symptoms and improving the rhinitis-related quality of life in college students with allergic rhinitis. Thus, Seogeum therapy may be an alternative nursing intervention for those suffering from allergic rhinitis.

• Journal of Korean Biological Nursing Science
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• 제15권4호
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• pp.230-236
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• 2013

Purpose: In this study, the effects of laughter therapy on a laughter index, cortisol and immunoglobulin of middle aged women were examined. Methods: A quasi-experimental nonequivalent control group pre/post-test design were used. The participants (n=54) included 27 in the experimental group and 27 in the control group. The data were collected from February through March of 2013. The experimental group participated in laughter therapy for 40 minutes per session, five times a week for a period of 2 weeks. The tool was used to measure pre/post-test laughter index, cortisol and immunoglobulin of middle aged women. Results: The results showed that laughter therapy was effective in increasing the laughter index (p<.001), and immunoglobulin IgA (p<.001), IgG (p<.001), and IgM (p=.010). Also, the stress hormone, cortisol of middle aged women decreased but non-significantly (p=.158). Conclusion: The result of the study indicates that laughter therapy may have an influence on nursing intervention and treatment effects to improve the laughter index and immunoglobulin of middle aged women.

• Journal of Korean Biological Nursing Science
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• 제10권2호
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• pp.113-120
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• 2008

Purpose: The aim of this study is to evaluate the effect of music therapy according to preferred music and to identify the effect of duration time and starting point of music therapy on anxiety and vital signs in spinal anesthesia operations. Method: These subjects were categorized into three groups based on the order of the date of operation. Data on anxiety and vital signs for this study were collected from them. The collected data were analyzed by $X^2$-test, t-test, paired t-test and ANCOVA. Result: The results of this study showed that preferred music, differences of duration times and starting points of music therapy didn't make significant differences in anxiety and vital signs among the three groups. However for anxiety, there was a meaningful difference within three groups. This result indicates even randomly chosen music by nurses considering the patients' age makes a meaningful difference in anxiety. Conclusion: Based on the results of this study, the conclusion can be made that music therapy is a useful nursing implementation to reduce anxiety in patients undergoing operations with spinal anesthesia.

• Journal of Korean Biological Nursing Science
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• 제17권2호
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• pp.179-187
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• 2015

Purpose: This study was done to evaluate the effects of a recreation therapy program on burn rehabilitation patients to determine if the program is an effective nursing intervention which can affect mental health problems and heart rate variability. Methods: Subjects were 54 hospitalized burn rehabilitation patients (25 in the control group, 29 in the experimental group). The experimental group participated 6 times in a recreation therapy program led by a qualified instructor. Brief symptoms inventory-18 (somatization, anxiety, depression) questionnaire, and heart rate variability were checked before and after the recreation therapy program. Results: The mental health scale showed significant differences in somatization (p<.001), anxiety (p<.001) and depression (p<.001). There was no significant difference in heart rate variability (autonomic activity, autonomic balance, stress resistance, stress parameter and fatigue, mean heart rate, electro-cardiac stability). Conclusion: The findings from this study suggest that a recreation therapy program is an effective nursing intervention to decrease the level of mental health problems of burn rehabilitation patients. However, a subsequent study is needed to develop an intervention program that will induce the effect of physiological parameters like heart rate variability (HRV).

• Journal of Korean Biological Nursing Science
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• 제24권4호
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• pp.227-234
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• 2022

Purpose: Smoking is a way of coping with anxiety and stress. This study aimed to identify the effects of forest-thermal combined therapy on anxiety and depression in smokers who desire to quit smoking. Methods: Thirty participants were included in the study, 15 in the experimental group and 15 in the control group. Those in the experimental group participated in a three-day forest-thermal combined therapy program. The program includes forest walks, meditation and thermal therapy in the charcoal kiln. Results: Before and after the program, physiological indicators such as cortisol, heart rate variability, and serotonin anxiety level using the state-trait anxiety inventory (STAI), and stress level using the psychosocial well-being index (PWI) were measured in both groups. The differences in STAI (p=.012) and PWI (p=.006) scores between the experimental and control groups were statistically significant. However, cortisol, heart rate variability, and serotonin were not significantly different between the two groups after the program. Conclusion: These results show that forest-thermal combination therapy effectively reduces anxiety and stress in smokers. It suggests that forest-thermal therapy can potentially increase smoking cessation rates.

• Physical Therapy Rehabilitation Science
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• 제12권1호
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• pp.33-42
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• 2023

Objective: This study aims to analyze the effect of regular exercise through the combined walking-oriented aerobic and resistance exercises using EX1 in young adults. Design: Experimental one group pre and post test Methods: Participants comprised17 healthy young adults. All subjects performed a combined exercise program for 10 times using EX1. We measured quadriceps muscle thickness using ultrasound. Additionally, the hand grip strength test, and sit and reach test were performed before and after the exercise. Through paired t-test, we investigated whether there was a statistically significant difference in the measurement results after exercise program. Results: The rectus femoris muscle contraction ratio showed significant difference after exercise(P< 0.01). In the sit and reach test, flexibility showed significant difference after exercise(P < 0.01). The hand grip strength test also showed significant difference after exercise(P < 0.05). Conclusions: Healthy young adults can effectively perform various exercises commonly performed in daily life using EX1.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1978년도 학술대회지
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• pp.19-20
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• 1978

• Journal of Microbiology and Biotechnology
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• 제27권10호
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• pp.1877-1884
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• 2017

Mesenchymal stem cells (MSCs) have been suggested as a primary candidate for cell therapy applications because they have self-renewal and differentiation capabilities. Although they can be expanded in ex vivo system, clinical application of these cells is still limited because they survive poorly and undergo senescence or apoptosis when transplanted and exposed to environmental factors such as oxidative stress. Thus, reducing oxidative stress is expected to improve the efficacy of MSC therapy. The milk protein lactoferrin is a multifunctional iron-binding glycoprotein that plays various roles, including reduction of oxidative stress. Thus, we explored the effect of lactoferrin on oxidative stress-induced senescence and apoptosis of human MSCs (hMSCs). Measurement of reactive oxygen species (ROS) revealed that lactoferrin inhibited the production of hydrogen peroxide-induced intracellular ROS, suggesting lactoferrin as a good candidate as an antioxidant in hMSCs. Pretreatment of lactoferrin suppressed hydrogen peroxide-induced senescence of hMSCs. In addition, lactoferrin reduced hydrogen peroxide-induced apoptosis via inhibition of caspase-3 and Akt activation. These results demonstrate that lactoferrin can be a promising factor to protect hMSCs from oxidative stress-induced senescence and apoptosis, thus increasing the efficacy of MSC therapy.

• 생물정신의학
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• 제13권2호
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• pp.82-94
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• 2006

Objectives : In order to explore effects of board-game therapy for cognitive rehabilitation in patients with schizophrenia, we investigated the change of executive cognitive function over a 2-month period of board-game therapy in patients with schizophrenia. Methods : Two groups of chronic schizophrenic inpatients were participated in this study. One group(n=21) were treated with board-game therapy for 2 months and the other control group(n=19) were not treated. For the evaluation of the executive cognitive function, a Wisconsin Card Sorting Test(WCST) was administered before and after the introduction of the board-game therapy. PANSS score change was also evaluated. Result : At the beginning of this study, there was no significant difference in performance of cognitive function tests, demographical data or clinical severity between both patient groups. After 2 months of treatment with the board-game therapy, the board-game therapy group showed significant improvements of executive cognitive function without any significant change of their schizophrenic symptoms. On the contrary, there was no change in control group. Conclusion : This study showed that a board-game therapy is effective for the enhancement of executive cognitive function in patients with chronic schizophrenia. A board-game therapy could be introduced with ease into psychiatric fields, such as inpatients' or outpatients' clinic wards and day hospital. Our result indicates that the board-game therapy is a promising tool for the enhancement of cognitive function, especially executive cognitive function and helpful for cognitive rehabilitation for schizophrenic patients.