• 한국조명전기설비학회:학술대회논문집
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• 한국조명전기설비학회 2004년도 춘계학술대회 논문집
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• pp.110-115
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• 2004

Examine merits and demerits and obstacle factor that exist to all direction of digital infratechnology that is supplied on industry whole according to development special quality of computer by development of computer and Information Technology and electricity electron information communication facility that basic impulse insulation level does not exist examined scorched earth or an interference problem factor and countermeasure of semiconductor degauss of factor and electricity electron information transmission system that is numbed or causes system down.

• Molecules and Cells
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• 제38권10호
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• pp.886-894
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• 2015

Macrophages are divided into two subpopulations: classically activated macrophages (M1) and alternatively activated macrophages (M2). BCG (Bacilli Calmette-$Gu{\acute{e}}rin$) activates disabled $na{\ddot{i}}ve$ macrophages to M1 macrophages, which act as inflammatory, microbicidal and tumoricidal cells through cell-cell contact and/or the release of soluble factors. Various transcription factors and signaling pathways are involved in the regulation of macrophage activation and polarization. We discovered that BCG-activated macrophages (BAM) expressed a new molecule, and we named it Novel Macrophage Activated Associated Protein 1 (NMAAP1). 1 The current study found that the overexpression of NMAAP1 in macrophages results in M1 polarization with increased expression levels of M1 genes, such as inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNF-${\alpha}$), Interleukin 6 (IL-6), Interleukin 12 (IL-12), Monocyte chemoattractant protein-1 (MCP-1) and Interleukin-1 beta (IL-$1{\beta}$), and decreased expression of some M2 genes, such as Kruppel-like factor 4 (KLF4) and suppressor of cytokine signaling 1 (SOCS1), but not other M2 genes, including arginase-1 (Arg-1), Interleukin (IL-10), transforming growth factor beta (TGF-${\beta}$) and found in inflammatory zone 1 (Fizz1). Moreover, NMAAP1 overexpression in the RAW264.7 cell line increased cytotoxicity against MCA207 tumor cells, which depends on increased inflammatory cytokines rather than cell-cell contact. NMAAP1 also substantially enhanced the phagocytic ability of macrophages, which implies that NMAAP1 promoted macrophage adhesive and clearance activities. Our results indicate that NMAAP1 is an essential molecule that modulates macrophages phenotype and plays an important role in macrophage tumoricidal functions.

• 대한간호
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• 제15권3호통권83호
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• pp.51-59
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• 1976

The assessmen tof characteristics of the learner is an essential factor basic to planning teaching. This study was performed during September through December 1975 to investigate the value-orientation of students and graduates of The School of nursing, na

• 수산경영론집
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• 제17권1호
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• pp.1-17
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• 1986

Since the middle of the 70s, the countries with the marine resources declared the exclusive water zone of two hundred miles. As a result, our country lacked many foreign fishing grounds. This awakened our perception of fishing grounds. The fishing ground is an important factor in the economical effectiveness of fisheries. The fishing ground must have the following basic conditions. 1. It must be the place the fishery resources inhabit and wander. 2. Their catching or aquaculturing must be possible by the technical methods. 3. It must have economic worth in the management. The fishing ground that achieves the above basic conditions is affected by the following factors. This is the factor of the fishing ground location. A. Natural factor 1). Suitable climate 2).Abundant resources 3). Good quality of the sea-bottom 4). Not to be pollutted area B, Economic factor 1). Be adjacent to fishing port and fisheries market 2). Good working conditions 3). Be abundant of economical resources C. Social factor 1). Be possible to work legally 2). Be permitted in the political relations 3). Be acquainted with the customs of foreign countries The fishing ground location is mainly affected by the natural factor of the above factors. The abundance of resources depends on the natural resources. The resources in the fishing ground have the cycle of developing period, maturing period, and decaying period according to the fishing efforts. The point that we sustainably yield the maximum of fishery resources is the changing point of maturing period and decaying period. We call this point MSY, so the resources of fishing ground should be managed by the MSY. Therefore, when we select the fishing ground location. We should judge the natural factor, the economic factor and the social factor synthetically according to the situation and environment, so we can achieve the efficient management.

• ETRI Journal
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• 제25권4호
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• pp.270-273
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• 2003

This paper presents a simple process to integrate thin-film inductors with a bottom NiFe magnetic core. NiFe thin films with a thickness of 2 to 3${\mu}m$ were deposited by sputtering. A polyimide buffer layer and shadow mask were used to relax the stress of the NiFe films. The fabricated double spiral thin-film inductor showed an inductance of 0.49${\mu}H$ and a Q factor of 4.8 at 8 MHz. The DC-DC converter with the monolithically integrated thin-film inductor showed comparable performances to those with sandwiched magnetic layers. We simplified the integration process by eliminating the planarization process for the top magnetic core. The efficiency of the DC-DC converter with the monolithic thin-film inductor was 72% when the input voltage and output voltage were 3.5 V and 6 V, respectively, at an operating frequency of 8 MHz.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9835-9839
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• 2014

Fisetin is an effective compound extracted from lacquer which has been used in the treatment of various diseases. Preliminary data indicate that it also exerts specific anti-cancer effects. However, the manner in which fisetin regulates cancer growth remains unknown. In this study, we elucidated interference of fisetin with targets of the nuclear factor ${\kappa}B$ signal transduction pathway activated by Epstein-Barr virus encoding latent membrane protein 1 (LMP1)in nasopharyngeal carcinoma (NPC) cells, Results showed that fisetin inhibited the survival rate of CNE-LMP1 cells and NF-${\kappa}B$ activation caused by LMP1. Fisetin also suppressed nuclear translocation of NF-${\kappa}B$ (p65) and $I{\kappa}B{\alpha}$ phosphorylation, while inhibiting CyclinD1, all key targets of the NF-${\kappa}B$ signal transduction pathway. It was suggested that interference effects of fisetin with signal transduction activated by LMP1 encoded by the Epstein-Barr virus may play an important role in its anticancer potential.

• 디자인학연구
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• 제19권1호
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• pp.283-292
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• 2006

본 연구는 디자인을 전공하려는 학생들이나 디자인내의 세분화된 진로선택을 하는데 갈등이 있는 대학생들을 위하여 '디자인 진로적성검사'를 개발하여 학생들이 자신의 적성에 맞는 세분화된 전공 및 진로분야를 선택하는데 도움을 주고자 하였다. 먼저 디자인 진로적성의 하위영역을 '직업공통기초능력', '디자인 기초능력', '디자인 전공심화능력'의 세 가지로 분류하고, 문헌 및 자료연구를 통하여 우선적으로 '직업공통기초능력'과 '디자인 기초능력'에 관하여 각 능력에 해당하는 세부요소와 요구되는 능력에 대한 정의를 시도하였다. 그 분류를 기반으로 문항시안 개발에 착수하였고, 개발된 문항은 연구의 단계별로 전문가협의회를 구성하여 3차에 걸쳐 타당성을 검증하고 기초조사가 진행되었다. 디자인 진로적성검사 개발을 위하여 구성된 예비척도(직업 공통기초능력 40문항, 디자인 기초능력 53문항)를 대도시에 소재하는 대학교의 디자인 전공계열 대학생 506명을 대상으로 기초조사를 실시하였다. 조사 결과는 탐색적 요인분석에 의해 직업공통기초능력은 네 개의 요인(대인관계능력, 목표 추진력, 문제해결력, 자기개발능력)으로 구성된 것으로 나타났으며, 디자인기초능력 문항은 다섯 개의 요인(디자인기초 소양, 컴퓨터 활용력, 재질감, 조형력, 색채감)으로 구성되어 있는 것으로 나타났다. 본 척도의 결과는 직업수행을 위한 디자인 진로적성으로써 매우 정교하고 현실감 있는 합당한 요인구조를 반영해주고 있다. 본 척도의 타당성에 대해 관련 타척도 및 준거집단과의 관계를 지속적으로 연구하고, 나아가서 디자인전공심화능력에 대한 척도를 개발한다면, 대학생들의 전공결정과 진로결정에 도움을 줄 수 있는 유용한 척도가 될 것이라고 본다.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2005년도 International Meeting on Information Displayvol.II
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• pp.1536-1537
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• 2005

We have made point electron sources using carbon nanotubes (CNTs). For the fabrication of point electron sources, CNTs were dispersed in a solution and attached on electrochemically etched W tips using electrophoresis. In our study, we have utilized various CNTs such as single-walled CNT (SWCNT), multiwalled CNT (MWCNT), and thin-MWCNT and threshold current, turn-on voltage, filed enhancement factor of each emitter have been studied upon a tube/bundle diameter and length. In addition, fieldemitted electron energy distribution of various CNT emitters is characterized.

• 한국식생활문화학회지
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• 제24권6호
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• pp.649-654
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• 2009

This study has a purpose of suggesting the basic data to achieve customer satisfaction by understanding the preference of each type of restaurant industry for the taste of customers in 20's referring to 8 images. In the preference for style of image in dining space, the participants responded that they prefer natural, modern and romantic image, and both male and female participants preferred natural image. Participants responded that they prefer natural, romantic and modern in sequence as their general preference for style of image in dining space, and male participants preferred modern and natural but female participants preferred romantic and natural. The survey that was conducted for different menus has suggested that the reasonable image for fast food is casual, hard casual and classic for hotel restaurant, casual for school restaurant, romantic for cafe, casual for western restaurant, simple for Japanese restaurant, classic and elegance for Chinese restaurant and natural for Korean restaurant. According to the result of the analysis of dining space image, factor 1 are called 'cold image (CI)' as they have simple and modern image, factor 2 are called 'soft image (SI)' as they have natural and romantic image, factor 3 are called 'warm image (WI)' as they have casual and elegance image and factor 4 are called 'hard image (HI)' as they have classic image.

• Biotechnology and Bioprocess Engineering:BBE
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• 제9권4호
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• pp.292-296
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• 2004

The recombinant soluble human tumor necrosis factor-alpha (hTNF-$\alpha$) was expressed in a yeast Saccharomyces cerevisiae and its cytotoxicity was evaluated. A cDNA encoding hTNF-$\alpha$ was placed under the control of two different promoters: a glyceraldehyde-3-phosphate dehydrogenase (GPD) promoter and a yeast hybrid ADH2-GPD promoter, consisting of alcohol dehydrogenase II (ADH2) and the GPD promoter. A Northern blot analysis revealed that, although variation in the expression level of hTNF-$\alpha$ existed among transformants, the higher expression was obtained with the GPD promoter. Expressed hTNF-$\alpha$ protein (rhTNF-$\alpha$) was successfully secreted into the culture medium, producing 2.5 mg per liter of culture filtrate, with no changes in cell growth. The bioassay for observing the cytotoxicity to the murine L929 fibroblast cell line, with serial dilution of rhTNF-$\alpha$, indicated that the secreted rhTNF-$\alpha$ was bioactive and its dose-response was improved eight to ten times over that of the E. coli-derived rhTNF-$\alpha$.