• Title/Summary/Keyword: BODY CONTRIBUTION

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Genetic variants of the growth differentiation factor 8 affect body conformation traits in Chinese Dabieshan cattle

  • Zhao, Shuanping;Jin, Hai;Xu, Lei;Jia, Yutang
    • Animal Bioscience
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    • v.35 no.4
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    • pp.517-526
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    • 2022
  • Objective: The growth differentiation factor 8 (GDF8) gene plays a key role in bone formation, resorption, and skeletal muscle development in mammals. Here, we studied the genetic variants of GDF8 and their contribution to body conformation traits in Chinese Dabieshan cattle. Methods: Single nucleotide polymorphisms (SNPs) were identified in the bovine GDF8 gene by DNA sequencing. Phylogenetic analysis, motif analysis, and genetic diversity analysis were conducted using bioinformatics software. Association analysis between five SNPs, haplotype combinations, and body conformation traits was conducted in 380 individuals. Results: The GDF8 was highly conserved in seven species, and the GDF8 sequence of cattle was most similar to the sequences of sheep and goat based on the phylogenetic analysis. The motif analysis showed that there were 12 significant motifs in GDF8. Genetic diversity analysis indicated that the polymorphism information content of the five studied SNPs was within 0.25 to 0.5. Haplotype analysis revealed a total of 12 different haplotypes and those with a frequency of <0.05 were excluded. Linkage disequilibrium analysis showed a strong linkage (r2>0.330) between the following SNPs: g.5070C>A, g.5076T>C, and g.5148A>C. Association analysis indicated these five SNPs were associated with some of the body conformation traits (p<0.05), and the animals with haplotype combination H1H1 (-GGGG CCTTAA-) had greater wither height, hip height, heart girth, abdominal girth, and pin bone width than the other (p<0.05) Dabieshan cattle. Conclusion: Overall, our results indicate that the genetic variants of GDF8 affected the body conformation traits of Chinese Dabieshan cattle, and the GDF8 gene could make a strong candidate gene in Dabieshan cattle breeding programs.

A Study on Optimal Spot-weld Layout Design of the Car Body Structure Using Topology Optimization (위상최적설계를 이용한 차체 점용접 배치 최적화 연구)

  • Kim, S.R.;Lee, C.W.;Kim, Mun-Yeong;Kim, C.M.;Yim, H.J.
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2012.04a
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    • pp.361-366
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    • 2012
  • In this paper, we propose the efficient technique that reduces the number of spot-welds and increases the structural rigidity by using the topology optimization technique. Eigen value analysis is used to evaluate the rigidity of the optimized model. As a first step, the topology optimization is performed to find optimal spot-weld distributions. In this study, the design objective is to maximize the weighted frequencies. The volume fractions of the weld components are used as design constraints, and also the densities of each element in the individual design space are used as design variables. And then, to consider the possibility of spot-weld failure, the contribution rate analysis was performed by using the orthogonal array method of DOE. The spot-welds in the rear panel part are reinforced according to estimation results of the contribution rate analysis. Finally, we obtained optimized spot-weld layout model which has the reduced number of spot-welds and the improved dynamic stiffness.

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Measurement of Nitrogen and Sulfur Deposition to Lake Paldang (팔당호로의 질소와 황성분 침적 측정)

  • Ghim Young Sung;Jin Hyoun Cheol
    • Journal of Korean Society for Atmospheric Environment
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    • v.21 no.1
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    • pp.39-48
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    • 2005
  • Nitrogen and sulfur deposition was measured on Lake Pal dang from March 2002 to October 2003. Wet and dry depositions were separately measured using wet- and dry-only samplers, respectively. In order to measure the dry deposition to the water body, a dry deposition sampler composed of three pans filled with pure water, called the deposition water, was used. Since ammonium was generally in excess in ambient air, more than half of ammonium was present in the gaseous form. Ammonium concentration was also generally higher than the sum of major anion concentrations in the deposition water because gaseous species were much easily deposited than the species in fine particles. Nevertheless, the contribution of gaseous ammonia to the deposition of ammonium was not high as well as that of particulate ammonium while the contribution of gaseous nitric acid was much higher than that of particulate nitrate. Annual wet deposition fluxes of nitrogen and sulfur were five and six times higher than their dry deposition fluxes, respectively. Except for ammonium, the dry deposition flux estimated in the present work was a half of the previous results. This was mainly caused by much smaller dry deposition velocities over the water than over the ground.

The Effect of Raised Heel Insole and Landing Height on the Shock Absorption Mechanism during Drop Landing (드롭 착지 시 착지의 높이와 키 높이 깔창이 충격흡수 기전에 미치는 영향)

  • Cho, Joon-Haeng;Kim, Ro-Bin
    • Korean Journal of Applied Biomechanics
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    • v.24 no.2
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    • pp.131-138
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    • 2014
  • The purpose of this study was to analyse the effect of the drop height on lower extremity and lower back kinematics and kinetics during drop landing with the use of raised heel insole. Furthermore we investigated the change that occurred in our body. Joint ROM, eccentric work and contribution to total work were calculated in 11 male college students performing drop landing with 8 motion analysis cameras and 1 forceplate. The result were as follows. First, the ROM and eccentric work were increased in all joints with the increase of the drop height. Second, the ankle ROM and eccentric work were decreased with the use of the insole. Third, the use of the lower back was increased as the use of the ankle decreased with the insole. Based on these results, we can infer that putting on the insole may contribute to chronic injury. We recommend not to use the insole during physical activity.

How Do Green Investment, Corporate Social Responsibility Disclosure, and Social Collaborative Initiatives Drive Firm's Distribution Performance?

  • PAMBUDI, Widiatmaka. F;DIAN, Wahdiana;Suherman, Suherman;LEONARDUS, Samodro Bintang A.M;Sukrisno, Sukrisno
    • Journal of Distribution Science
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    • v.20 no.4
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    • pp.51-63
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    • 2022
  • Purposes: The purpose of this study is to develop and test a possible model that investigates the relationships between green investment, CSR disclosure, social collaboration initiatives, and firm distribution performance to deal with environmental change because it's become the major stakeholder since it affects increasingly global company performance index. Research methodology: In this study a quantitative method was adopted. The 220 respondents were owners and managers of manufacturing enterprises from Indonesia. The structural equation model (SEM) was used to test the hypotheses, and the Partial Least Square (SmartPLS) was used as the data analysis tool. Findings: The study's finding shows that green investment has a significant effect on CSR disclosure, and CSR disclosure has a positive relationship with social collaborative initiatives and the firm's distribution performance. Similarly, social collaborative initiatives also significantly impact a firm's distribution performance. Limitations: This study uses variables that are still abstract and have not been able to regress the dimensions contained there into conclusion variables for each antecedent variable. In addition, this study only used a sample with a small scope, namely Central Java Province, Indonesia. Contribution: The findings of this study contribute to the body of literature in the field of organizational management and support the agency and stakeholder theories. For the practical contribution, this study provides the way to build and implement green-based investment strategies as a competitive edge and improve firm's distribution performance.

Analysis of Exposure Pathways and the Relative Importance of Radionuclides to Radiation Exposure in the Case of a Severe Accident of a Nuclear Power Plant (원전 중대사고시 피폭경로 및 핵종의 방사선 피폭에 대한 상대적 중요도 해석)

  • Hwang, Won-Tae;Suh, Kyung-Suk;Kim, Eun-Han;Han, Moon-Hee;Kim, Byung-Woo
    • Journal of Radiation Protection and Research
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    • v.19 no.3
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    • pp.209-221
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    • 1994
  • In the case of a severe accident of a nuclear power plant, the whole body dose and the relative importance of the radionuclides during the lifetime of an exposed person were estimated for each exposure pathway with distances from the release point. The external exposure pathways due to immersion of radioactive cloud and deposition of radioactive materials on the ground, and the internal exposure pathways due to inhalation and ingestion of contaminated foodstuffs were considered. The effects due to the ingestion of contaminated foodstuffs were estimated considering the variation of radioactive concentration in the foodstuffs according to deposition time and elapsed time after deposition using a dynamic ingestion pathway model applicable to Korean environment, named 'KORFOOD'. As the results up to 80 km from the release point, the effects due to ingestion of contaminated foodstuffs showed the highest contribution to total exposure dose. The contribution of I isotopes was the highest in the case of the external dose due to immersion of radioactive cloud and internal dose due to inhalation. The contribution of Cs isotopes was highest in the case of the external dose due to deposition of radioactive materials on the ground. In the case of the internal dose due to ingestion of contaminated foodstuffs, Cs deposition in summer and Sr deposition in winter, respectively, were the most dominant radionuclide to whole body.

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Relationship between inflammation biomarkers, antioxidant vitamins, and bone mineral density in patients with metabolic syndrome

  • Lee, Ye-Song;Kim, Mi-Sung;Choi, Kyung-Suk;Kim, Ju-Yong;Bae, Woo-Kyung;Kim, So-Hye;Sohn, Cheong-Min
    • Nutrition Research and Practice
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    • v.5 no.2
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    • pp.150-156
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    • 2011
  • Few studies have shown the correlation between metabolic syndrome and bone mineral density (BMD). The main pathogenic mechanisms of metabolic syndrome rely on chronic low-level inflammatory status and oxidative stress. There are few studies that examine the gender-specific effects of inflammation and antioxidants on BMD. In this study, we evaluated the relative contribution of these factors in patients with metabolic syndrome. We conducted a cross-sectional study of 67 men and 46 postmenopausal women with metabolic syndrome; metabolic syndrome was defined as having three or more metabolic syndrome risk factors. BMD, body fat mass, and lean body mass were evaluated. We also examined the levels of high sensitive C-reactive protein (hs-CRP), interleukin-6 (IL-6), adiponectin, vitamin E, and C in serum. Log-transformed hs-CRP levels were significantly higher in lumbar spine osteoporotic subjects than in normal subjects for women but not for men. There was no significant difference between the normal group and the osteoporotic group in other inflammatory markers. Stepwise regression analyses for BMD of the lumbar spine showed that lean body mass and vitamin E were significant determinants in men. Lean body mass and log-transformed hs-CRP were significant determinants in women Analysis for BMD of the femoral neck showed that lean body mass was a significant determinant for both men and women. There was no significant factor among the inflammatory markers or antioxidant vitamins affecting the femoral neck BMD for either gender. In conclusion, while hs-CRP is an independent predictor of the BMD of the lumbar spine in women, vitamin E showed profound effects on BMD in men but not women with metabolic syndrome.

Relationship of Participation in Jazz Dance to Body Image and Mental Healt (재즈댄스 참가와 신체상 및 정신건강과의 관계)

  • Choi, Sung-Ae
    • The Journal of the Korea Contents Association
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    • v.8 no.8
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    • pp.196-205
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    • 2008
  • The purpose of this study was to examine the relationship of participation in jazz dance to body image and mental health in an attempt to make a contribution to the spread of jazz dance. The subjects in this study were 183 people who were selected by purposive sampling from a population of Seoul and Gyeonggi province residents who were at the Western age of 18 and up. The selected people took general education courses at colleges, attended cultural centers or fitness clubs, or learned dance for all. One instrument used in this study to assess their body image was Jourard and Secord(1954)'s Body Cathexis Scale, which was modified into six factors and 39 items. The other was Kim Gwang-il, et. al.(1978)'s 46-item inventory, which translated Rickles and Rock(l976)'s SCL-90 with 90 items to suit Korean circumstances. That inventory was modified into 31 items and four factors. For data handling, factor analysis, reliability analysis, regression analysis and path analysis were utilized. The findings of the study were as follows: 1. The extent of jazz dance participation had an impact on their body image. Those who performed jazz dance more frequency had a better image about their health and the lower part of the body. 2. The level of jazz dance participation exerted an influence on their mental health. A longer participation term led to more interpersonal sensitivity, and a higher participation frequency was followed by more somatization. 3. Concerning the causal relationship of participation in jazz dance to body image and mental health, the participation frequency affected health, the image of the lower part of the body and somatization in the firsthand manner, and the image of the lower part of the body had a firsthand impact on interpersonal sensitivity, hostility, anxiety and depression. Accordingly, the image of the lower part of the body played a crucial role as a parameter in the relationship between the jazz dance participation frequency and mental health.

Study on Food Intake and Food Consumption Pattern of Adults as a Part of Total Diet Study (총식이조사를 위한 식품의 소비형태 및 식품섭취량 조사 연구)

  • 계승희
    • Journal of Nutrition and Health
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    • v.30 no.1
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    • pp.61-74
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    • 1997
  • A dietary intake survey in 2 major city area was conducted as a part of the study which determined the level of exposure of people to harmful substances in foodstuff. A total of 800 randomly selected men and women aged 20-49 yr and living in the cities of Seoul and Taegu were invited to participate in the survey. All subjects were interviewed by trained dietitians to answer for demorgraphic characteristics and dietary intake for 1 day by 24hr recall method, and asked to record what day ate for following 2 more days by themselves. Results were analyzed and presented for the amount and frequency of food intake by area, sex body weight. Food consumed most by adults resifing in these 2 city area was rice and followed by kimchi in the amount of 225.7g/persn/day and 85.0g/person/day, respectively. In the list of foods consumed most frequently, items used for condiments were included in addition to rice and kimchi. And the total daily intake of food per person was summed up to be 1, 534g for men and 1, 304g for women. Considerable part of this sexual difference in total intake was originated from the difference in beverage consumption including alcoholic beverages and the higher intake of certain foodstuff due to higher body weight of men. Intake data were presented din terms of per capita and per kg body weight, and compared among adults in different categories of body weight, also. The data gathered here, food intake by individuals, reflect our own dietary culture in terms of food assortment and relative contribution of each food item to total food intake include the consumption of "extreme" eaters might be found useful also especially for the sake of food safety such as risk assessment using ADI and PTWI for contaminants in the food supply.od supply.

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A Numerical Study on the Growth Factors in Anoplocnemis (장수허리 노린재(Anoplocnemis dallasi K.)에 있어서 成長因子에 관한 數理生物學的 硏究)

  • Park, Sang-Ock;Lee, Chang-Eon
    • The Korean Journal of Zoology
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    • v.18 no.4
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    • pp.197-220
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    • 1975
  • Applying the factor analysis to the values standardized from the measured values for instars in seven body parts of A. dallasi, it is summarized as follows: 1. All seven aspects are found to have the four growth factors. 2. The first factor is acceptable as a general factor and a growth promoting factor, whereas the rest three factors are indicated as a group factor in most cases. 3. The seven aspects are classifiable into three groups- the first group of the body length, the middle leg and the hind leg, the second group of the forg leg, and the third group of the width of pronotum, the antenna, the rostrum. But the second group is similar type to the first group in the influence of the factors. 4. The communality of the middle leg is the highest, while that of the body length is the lowest. The uniqueness of the middle leg is the lowest, while that of the body length is the highest. 5. The contribution of the growth factor tends to inrease according to the development of the instars. 6. The correlation for a young instar larva has a tendency to become low, but that for an advanced instar larva tends to become high.

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