• Journal of Microbiology and Biotechnology
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• 제12권1호
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• pp.8-13
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• 2002

The isoflavone glycosides are hydrolyzed by ${\beta}$-glucosidase from gut microbes to the bioactive aglycones. However, the specific bacteria from the human intestinal tract that are involved in the metabolism of these compounds are not known. This study was undertaken to develop a fermented soymilk which converts isoflavones to the more bioactive aglycones form using a Bifidobacterium strain. The ${\beta}$-glucosidase activity of 15 Bifidobacterium strains were measured during cell growth. Among them, Bifidobacterium sp. Int-57 was selected for this study, because it has the highest ${\beta}$-glucosidase activity. Growth, acid development, ${\beta}$-glucosidase activity, and the hydrolysis of daidzin and genistin were investigated in four soymilks inoculated with Bifidobacterium sp. Int-57. After 12 h of fermentation, the counts of viable Bifidobacterium sp. Int-57 in all the soymilks reached a level of more than $10^8$ cfu/ml, which was then maintained. The pH of soymilks started to decrease rapidly after 6 h of fermentation and leveled off after 18 h. The titratable acidity of BL# 1 soymilk, BL#2 soymilk, and JP#l soymilk increased from 0.18 to 1.21, 1.15, and $1.08\%$ over the fermentation period, respectively. After 24 h of fermentation, the $\beta$-glucosidase activity in BL#1 soymilk, BL#2 soymilk, JP#l soymilk, and JP#2 soymilk increased to 59.528, 40.643, 70.844, and 56.962 mU/ml, respectively. The isoflavone glycosides, daidzin and genistin, in soymilks were hydrolyzed completely in the relatively short fermentation time of 18 h. These results show that Bifidobacterium sp. Int-57 can be used as a potential starter culture for developing fermented soymilk which has completely hydrolyzed isoflavone glycosides.

• 대한한방부인과학회지
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• 제27권3호
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• pp.158-167
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• 2014

Objectives: This study aims to report the effect of Korean medicine treatments on a pelvic inflammatory disease (PID). Methods: The patient was treated with Qingbaozhuyu-tang, acupuncture at Jungwan (CV12), Gihae (CV6), Taechung (LR3), Hapgok (LI4), Sameumgyo (SP6), Sangryo (BL3), Charyou (BL32), Jungryo (BL33), Haryo (BL34), Cheonchu (ST25), Pungryung (ST40), Duyu (ST8), Taeyang (EX-HN5). And we evaluated treatment effects by visual analogue scale (VAS) and Urine analysis (UA) Finding. Results: After treatments, the symptoms such as lower abdominal pain, pelvic pain and fever were improved and there were no abnormal findings in urine analysis. Conclusions: This study suggests that Korean medicine treatments show effective on PID treatment.

• 혜화의학회지
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• 제22권1호
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• pp.217-224
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• 2013

Objectives : The object of this study is to report the effectiveness of Korean medicine treatment and to urge in-depth research on plantar fasciitis. Methods : Four patients, diagnosed as plantar fasciitis, were treated by Korean medicine interventions; acupuncture at K13, BL60, BL40, indirect moxibustion at local region, oral intake herbal medicine and Korean physical therapy on plantar fascia. Visual analog scale(VAS) was adpoted as a method of measuring the effect of treatment on plantar pain. Results : As a result, the plantar pain decreased and VAS score was declined at three cases. However, at one case, the symptom was not changed and VAS score was same. Conclusions : Korean rehabilitative complex therapy can be effectively used for plantar fasciitis. Further studies are needed to set up a rehabilitation protocol with Korean medicine interventions on this disease.

• 천문학회보
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• 제43권1호
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• pp.37.1-37.1
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• 2018

A Korean VLBI Network key science program, the Interferometric Monitoring of Gamma-ray Bright AGNs (iMOGABA) program continues to reveal the nature of the gamma-ray flares in active galactic nuclei (AGNs). Here in this presentation, we would like to introduce an interesting story about four gamma-ray bright AGNs - BL Lac, 1633+382, 3C 84, and M87 - based on the recent results of the iMGOABA. The results will include a) a sad story of an 'orphan' gamma-ray flare from BL Lac, b) a position offset of 40 pc for a gamma-ray flaring site from the radio regions in 1633+382, c) a position alignment of a gamma-ray flaring site with a central engine region in 3C 84, and d) a flat millimeter spectrum of a core in M87 revealed by the iMOGABA.

• The Korean Journal of Ecology
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• 제6권3호
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• pp.208-226
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• 1983

The vegetation of Odongdo island was surveyed over twenty-nine times from April, 1982 to August, 1983. This island is located at 127。46'05'∼127。39'37'E. longitude and 34。40'20'∼34。48'14'N. latitude. The vegetation of this island consisted of 94 families, 261 genera, 314 species, 53 varieties and 6 formae. And among them were 170 species of woody plants and 203 species of herbs. The community of evergreen broad-leaved trees comprised a total of 44 species including Sasa coreana Nakai and camellia japonica L. and the distribution of evergreen broad-leaved trees was good in this island as a whole. Sasa coreana Nakai, Castanopsis cuspidata var. sieboldii Nakai, Ficus erecta Thunb., Ficus nipponica Fr. et Sav, Stauntonia hexaphylla (Thunb.) Decne, Cinnamomum japonicum Sieb., Machilus thunbergii S. et Z., Lozoste lancifolia (S. et Z.) Bl., Ilex intergra Thunb., Camellia japonica Thunb., Hedera rhombea Bean and Ardisia japonica Bl. etc. in this island were autochthonous flora and their preservation is required.

• Journal of applied mathematics & informatics
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• 제40권5_6호
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• pp.813-830
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• 2022

The generating functions of the divisor function σ_s(n) = Σ_0<d|n d^s are quasimodular forms. In this paper, we find the basis of the space of quasimodular forms of weight 6 on Γ₀(10) consisting of Eisenstein series and η-quotients. Then we evaluate the convolution sum Σ_ak+bl+cm=n σ(k)σ(l)σ(m) with lcm(a, b, c) = 10 and Σ_al+bm=n lσ(l)σ(m) and Σ_al+bm=n σ₃(l)σ(m) with lcm(a, b) = 10.

• 한국식품영양과학회지
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• 제36권3호
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• pp.276-283
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• 2007

5주령의 C57BL/6 mice종 암컷 40수를 2주간의 적응기를 거쳐, 평균 체중 $17.9{\pm}0.9\;g$인 실험동물을 완전임의배치로 한 군당 10수씩 4군으로 나누어 실험식이는 동맥경화식이(control)에 이소플라본을 첨가한 실험식이를 각각 8주간 급여하면서 사육하였다. 이소플라본의 첨가량은 식이 100 g 당 10 mg(IF-10)과 40 mg(IF-40) 및 100 mg(IF-100)이 되도록 조정하여 제조하였다. 이소플라본의 섭취는 체중증가량에 영향을 미치지 않는 것으로 나타났으며 식이효율은 각 군 간의 유의적인 차이를 보이지 않았다. 이소플라본 섭취에 의한 혈장 TG 농도는 대조군에 비해 이소플라본을 첨가한 식이를 섭취한 군에서 감소하는 추세를 보였다. 총 콜레스테롤 수준은 모든 실험군에서 증가하는 경향을 보였으나 8주 후의 농도 변화는 대조군에 비해 이소플라본을 첨가한 식이를 섭취한 군에서 감소하는 추세를 보였다. 세포부착물질인 MCP-1과 지질과산화물인 TBARS의 생성량은 이소플라본의 첨가량이 높을수록 현저하게 감소되는 결과를 보여 농도의존적인 효과를 보였다. 간의 TG와 총 콜레스테롤 농도는 이소플라본의 첨가량이 높을수록 감소하는 것으로 나타났으며(p<0.05), 간의 항산화 영양소인 glutathione 함량은 이소플라본을 100 mg 제공한 IF-100에서 유의적으로(p<0.05) 높은 수준을 보였다. 간의 항산화 효소계 활성은 대조군에 비해 이소플라본을 첨가한 식이를 섭취한 군에서 대체로 높게 나타났으며 특히 이소플라본 100 mg을 첨가한 식이를 섭취한 IF-100에서 현저하게 높은 수준을 보였다. 이상의 결과들로 미루어 볼 때 이소플라본의 섭취가 혈장의 중성지방을 저하하고 항염증, 항산화효과를 보여 동맥경화예방에 효과가 있는 물질로 사료된다.

• Journal of Acupuncture Research
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• 제27권5호
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• pp.125-134
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• 2010

Objectives : There has been a need for developing and establishing operational curriculum for the education of acupuncture, but defining the level and step of the acupuncture education in clinical perspectives was not thoroughly recognized so far. Methods : We analysed the usage of acupuncture points in the official textbook to recognize the most frequently used acupoints in clinical medicine. It was found that $ST_{36}$ $LI_4$ $SP_6$ $HT_7$ $LR_3$ $CV_{12}$ $BL_{23}$ $CV_6$ $BL_{20}$ $CV_4$ $LI_{11}$ $PC_6$ $KI_3$ $GB_{20}$ $GV_{20}$ $GB_{34}$ $BL_{18}$ $GV_{14}$ $BL_{17}$ $BL_{40}$ are the most frequently used 20 acupuncture points and GB(足少陽擔經), CV(任脈), ST(足陽明胃經) are the most frequently used meridians. Results : The $ST_{36}$, $GB_{34}$, $LI_{11}$ and GB(足太陽膀胱經) meridian are most frequently used for muskuloskeletal disease, $ST_{36}$, $LI_4$, $LI_{11}$ and GB(足太陽膀胱經) meridian are most frequently used for neuromuskular disease, and $ST_{36}$, $CV_{12}$, $BL_{20}$ and CV(任脈) meridian are most frequently used for the digestive system disorders. Conclusions : This study was the first systematic approach to get essential acupuncture points for the education of clinical perspectives of TKM especially for the acupuncture and moxibustion. We found that the $ST_{36}$, $GB_{34}$, $LI_{11}$ and GB(足太陽膀胱經) are the most frequently used acupuncture point and meridian. This study will be used for the development of TKM clinical curriculum.

• 한국임상수의학회지
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• 제24권3호
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• pp.432-436
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• 2007

개 모낭충증의 새로운 치료법을 확립하기 위하여 항생제의 약침과 일반 치료의 병행을 이용한 치료 효과를 조사하였다. 본 연구에서는 모낭충으로 진단된 개 3두를 이용하였다. Enrofloxacin의 약침을 폐수(BL13) 위중(BL40), 대추(GV14), 족삼리(ST36), 합곡(LI04), 곡지(LI11) 및 삼음교(SP06)의 혈위에 각각 5주간 실시하였다. 또한 일반 치료법인 invermectin과 0.05% amitraz 약욕을 5주간 추가로 실시하였다. 소양증, 찰과상, 홍반 및 탈모와 같은 임상증상은 약침과 일반치료에 의해서 치료 전에 비하여 현저하게 완화되었다. Case 1은 4주 후에 완치되었고, case 2는 5주 후에 증상이 약간 잔존하였으며, 그리고 case 3은 5주 후에 완치되었다. 혈중 백혈구 수는 치료와 더불어 모든 케이스에서 감소하는 경향을 보였으나, 호중구/림프구 비율은 일정한 경향을 나타내지 않았다. 5주째 병리조직 검사 소견상에서 case 1과 case 3은 뚜렷한 병리조직학적 변화가 관찰되지 않았으나, case 2는 경도의 변화가 관찰되었다. 결론적으로 개 모낭충에 이환된 본 환축들은 항생제 약침과 일반 치료법의 병행으로 양호한 치료반응을 나타낸 증례이었다.

• 대한수의학회지
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• 제28권2호
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• pp.227-239
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• 1988

In order to investigate the morphological characteristics of dendritic cells in the mammary gland, the appearance on the clear cells(CLs) or ATPase-positive dendritic cells(APDCs) have been observed by the light microscope. The results obtained were summarized as follows: CLs were observed in the mammary tissues of the experimental animals, such as mice, rats, guinea pigs, rabbits, cats, dogs, pigs, cows and Korean native goats, and these CLs were confirmed as the ATPase-positive cells of typical dendritic appearance(APDCs), The APDCs were distributed in between the secretory epithelial cells, between the secretory epithelial cells and the myoepithelial cells, the basal area of the secretory epithelial cells, the interalveolar and interlobular connective tissues, and in between the epithelial cells of secretory duct. The APDCs were observed more frequently during the middle period of lactation than the other periods, and were irregularly or uniformly distributed according to the location. During the middle period of lactation, there were notable quantitative differences in the APDSs depending on the mammary glands of mice, rats, guinea pigs, rabbits and cats, The most prominent differences were recognized among the mice, guinea pigs and cats. The number of AP DCs per unit area was statistically fewer in the guinea pigs($209.07{\pm}51.75cells/mm^2$) than in the mice($221.00{\pm}50.94cells/mm^2$) and cats($223.56{\pm}49.68cells/mm^2$) (respectively, p<0.05, p<0.05). Among the A/J, DBA/2, C57BL/6 and NIH(GP) mice, the mean densities of APDCs was statistically significantly fewer in the DBA/2($196.65{\pm}43.47cells/mm^2$) than in the C57BL/6($248.40{\pm}41.40cells/mm^2$) and NIH(GP) ($235.98{\pm}55.89cells/mm^2$) (respectively, p<0.0000, p<0.0000), however no significant difference between the C57BL/6 and the NIH(GP) was recognized (p>0.1). Among the F344, SD and W rats, the statistical analysis were confirmed that there were significantly fewer APDCs in the F344($198.72{\pm}47.61cells/mm^2$) than in the SD($227.70{\pm}41.40cells/mm^2$) and W($223.56{\pm}49.68cells/mm^2$) (respectively, p<0.0000, p<0.0001), however no significant difference between the SD and the W was recognized(p>0.1). The mean difference between the inbred and the noninbred counts in the mice was statistically significant (p<0.0001), and the similar result was presented in the rats(p<0.0000).