• 한국동물위생학회지
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• 제18권1호
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• pp.22-32
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• 1995

A partial characteristics and pathogenicity of Aeromonas salmonicida strain isolated from diseased cultured eel were studied. On the biochemicial characteristics of the isolate strain was classified into atypical Aeromonas salmonicida : the characteristics of the isolate strain differed from those of the subspecies of Achromogenes, masoucida and salmonicida. It strain was named atypical Aeromonas salmonicida EL-1 and it grew at optimal pH 7.5 and l% Nacl. In the pathogenicity test, at one to two days post infection, the motality of artificially infected eels with $1{\times}10^8$ and $1.0{\times}10^7$ cfu/fish group was 100%, and at three days pos-infection, in the $1.0{\times}10^6$ /cfu /fish infected group, the epizootic haemorrhagic ulcer was developed, and haemorragic red sports were formed around abdomen and fins and its died (40%). Total cell protein peptide bands of the A. salmonicida EL-1 were presented betweeon 11.8~102 Kd in molecular weight by the electrophoretic analysis and appeared 28 bands in all. Drug sensitivity of atypical A. salmonicida EL-1 strain was sensitivity to chlorampenicol, gentamicin, kanamycin, streptomycin and sulfamethoxazole /trimethoprim and intermidiate to ampiclin and neomycin resistant to cephalotin, erythromycin, lincomycin and tetracycline.

• Journal of Oral Medicine and Pain
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• 제25권2호
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• pp.229-234
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• 2000

The patient, 62-years-old woman, had a constant dull pain in the right mandible and an intermittent spontaneous burning sensation of the mouth. The pain began 6 months ago. About 5 years ago, a trauma in her right mandible which was so severe that kept her in the hospital for 2 days. This was followed by mouth opening disturbance with pain for about 2 years. However, she did not have a treatment for the temporomandibular disorder symptoms. After then, she experienced the trigeminal neuralgia characterized by an electrical pain which lasted about 30 minutes in her right face and head when touching the skin or hair. After taking a year course treatment of trigeminal neuralgia, the symptom disappeared. The pain was a constant dull pain and a intermittent burning pain which are contradictory. And the pain responded to various modalities such as physical therapy, anti-inflammatory drug, carbamazepine, and amitriptyline, among which carbamazepine was most effective. The diagnosis was clinically made as an atypical trigeminal neuralgia. The term 'atypical' is used when there is something unknown and the problem is not identified. It is thought that an atypical pain may be approached in the perspective of chronic pain, neuropathic pain, and myofascial pain, the mchanisms of which are poorly understood. As the knowledge of pain physiology improves, there needs to be modification and re-evaluation. Pain disorders must be classified on the basis of an understanding of the underlying mechanism and etiology.

• 한국멀티미디어학회논문지
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• 제24권8호
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• pp.1076-1089
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• 2021

Among the currently used knowledge-based authentication methods for smartphones, text and graphic-based authentication methods, such as PIN and pattern methods, use a display unit and a touch function of the display unit for input/output of secret information. Recently released smartphone form factors are trying to transform into various forms, away from the conventional bar and slate types because of the material change of the display unit used in the existing smartphone and the increased flexibility of the display unit. However, as mentioned in the study of D. Choi [1], the structural change of the display unit may directly or indirectly affect the authentication method using the display unit as the main input/output device for confidential information, resulting in unexpected security vulnerabilities. In this paper, we analyze the security vulnerabilities of the current mobile user authentication methods that is applied atypical form factor. According to the analysis results, it seems that the existing display-dependent mobile user authentication methods do not consider emerging security threats at all. Furthermore, it is easily affected by changes in the form factor of smartphones. Finally, we propose countermeasures for security vulnerabilities expected when applying conventional authentication methods to atypical form factor-based smartphones.

• 생물정신의학
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• 제10권2호
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• pp.186-196
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• 2003

Objects:The authors devebped a behavioral modification program for oveweight outpatients with schi-zophrenia and bipolar disorder will had teen treated with atypical antipsychotics, and evaluated the applicability of this program to outpatients Methods:Two men and nine women who had been treated with atypical antipsychotics and will had gained at least 5 percent of their pre-treatment body weight for 10 weeks, attended a behavioral modification program. The patients' weight, body mass index and the diet-activity scale were assessed and were compared with those of a matched comparison group will dd not attend the behavioral modification program Results:The body weight of patients who attended the behavioral modification program reduced with statistical significance, The treatment group showed significant improvement in diet-related items but not in activity-related items of the diet-activity scale Conclusions:This study suggested the applicability of a eehavioral mcdification program on weight reduction to overweight patients taking atypical antipsychotics for the frrst time in Korea Additional large scale studies are needed to validate the effectiveness of this program.

• 한국콘텐츠학회논문지
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• 제17권8호
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• pp.14-26
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• 2017

컴퓨터 기술의 발전에 따라 많은 디지털디자인도구가 개발되어 활용되면서 디지털 프로세스에 의한 구체적인 방법론의 연구가 증가하고 다양한 비정형 형태가 나타나고 있지만, 건축 형태 생성에 있어 접근성과 다양한 환경을 추구하는 모바일기술의 적용과 실용화에는 한계를 보여주고 있다. 이에 본 연구에서는 선행연구와 모바일활용 현황을 분석하여 연구의 필요성을 인지하고, 모바일환경에서 비정형 형태 생성 가능성을 제시 하고자 한다. 즉, 비정형 건축의 아이디어구현과 학습을 위한 스마트 모바일 애플리케이션의 필요성을 인지하고 디자인 프로세스 중 건축초기단계에서 비정형 형태생성을 가능하게 하는 스마트모바일 애플리케이션 기술의 기본을 설정 하는 것이다. 이를 위해 본 연구에서는 프로세스에 의한 분석적 적용이 아닌 선택적 적용의 방법을 제시하여 모바일적용의 가능성을 제시하고자 한다.

• Journal of Korean Neurosurgical Society
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• 제60권6호
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• pp.661-666
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• 2017

Objective : Atypical meningioma is rare tumor and there is no accurate guide line for optimal treatment. This retrospective study analyzed the prognostic factors, the effect of different methods of treatments and the behavior of atypical meningioma. Methods : Thirty six patients were diagnosed as atypical meningioma, among 273 patients who were given a diagnosis of meningioma in the period of 2002 to 2015. Age, gender, tumor location, Ki 67, Simpson grade and treatment received were analyzed. We studied the correlation between these factors with recurrence, overall survival rate and progression free survival. Results : Median overall survival time and progression free survival time are 60 and 53 (months). Better survival rate was observed for patients less than 50 years old but with no statistical significance (p=0.322). And patients with total resection compared with subtotal resection also showed better survival rate but no statistical significance (p=0.744). Patients with a tumor located in skull base compared with patients with a tumor located in brain convexity and parasagittal showed better progression free survival (p=0.048). Total resection is associated with longer progression-free survival than incomplete resection (p=0.018). Conclusion : We confirmed that Simpson grade was significant factor for statistically affect to progression free survival in univariate analysis. In case of skull base atypical tumor, it is analyzed that it has more recurrence than tumor located elsewhere. Overall survival was not affected statistically by patient age, gender, tumor location, Ki 67, Simpson grade and treatment received in this study.

• 대한세포병리학회지
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• 제4권2호
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• pp.81-86
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• 1993

The recently proposed Bethesda system for cervical/vaginal cytology has made a standardization related to "atypia". In cellular changes due to inflammation or repair, the word "benign cellular change" has been suggested as a substitute for atypia. Terminology related to atypical cells may become standardized, but the cytologic criteria has not been well defined yet. We evaluated 160 cases of atypical squamous cells of undetermined significance(ASCUS) by the Bethesda Sys4em(TBS). Among 30,428 cases screened, a cytologic diagnosis of ASCUS was made in 498 cases(1.6%) and 160 cases were histologically verified ASCUS was diagnosed based on nuclear enlargement and nonclassical signs of condyloma. The results are as follows: One hundred and twenty three cases(76.9%) revealed chronic cervicitis. Thirty seven cases(23.1%) demonstrated squamous intraepithelial lesion. Among intraepithelial lesions, condyloma and mild dysplasia were 28 cases(75.7%). Moderate and severe dysplasia were 5 cases(13.5%) and 4 cases(10.8%), respectively. it is concluded that patients with ASCUS should be colposcopically examined.

• 대한세포병리학회지
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• 제13권1호
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• pp.14-20
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• 2002

Cytologic and histopathologic features and human papillomavirus (HPV) DNA detection associated with 101 cervicovaginal smears which are ciassified as 'atypical squamous cells of undetermined significance, rule out high grade squamous intraepithelial lesion(ASCUS, R/O HSIL)' were reviewed and compared to 89 smears of 'ASCUS, not otherwise specified(NOS)'. Cytologic fieatures of ASCUS, R/O HSIL included atypical single small cells(36.6%), hyperchromatic tissue flagments(35.6%), atypical metaplastic cells(18.8%), endometrial cell-like clusters(5.9%), and atypical parakeratotic cells(3.0%). A final diagnosis of HSIL on biopsy was assigned to 47(54.0%) of 87 women with ASCUS, R/O HSIL and to 13(14.6%) of 89 women with ASCUS, NOS (p=0.000). There was no difference in HPV DNA detection late between ASCUS, R/O HSIL and ASCUS, NOS smears. These data suggest that subclassification of ASCUS is helpful to manage patients because ASCUS, R/O HSIL is more often associated with an underlying HSIL on biopsy. Therefore, women with ASCUS, rule out HSIL should be actively managed with colposcopic examination.

• Tuberculosis and Respiratory Diseases
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• 제43권3호
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• pp.440-448
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• 1996

Bronchial carcinoid tumors are uncommon, constituting approximately 3-5% of all primary lung cancers. Classification of these tumors has evolved substantially as our understanding of the cellular, biologic, and clinical aspects of these neoplasms has improved. Initially, bronchial carcinoids were thought to be benign and therefore were classified as bronchial adenomas. Currently, however, they are well recognized as having the potential for both local invasion and distant metastatic involvement. Consequently, carcinoid tumors are frankly malignant. Thus bronchial adenoma is a misnomer that should no longer be used for bronchial carcinoids. Most investigators currently favor classifying carcinoid tumors as a type of neuroendocrine neoplasm because of their potential to secrete a variety of chemical substances found in both the central nervous system and the epithelial cells of numerous organs. Bronchial carcinoids are usually characterized by a slow growth pattern and a low incidence of metastasis, and histologically conformed by the azurophil staining and the presence of the characteristic neurosecretary granule on electron microscopy. Atypical carcinoid tumor was first defined by Arrigoni et al, who proposed the following criteria for separation of atypical carcinoid from typical carcinoid tumor : 1) increased mitotic activity with 1 mitotic figure per 1-2 high power fields(or 5-10 mitoses /10 HPF), 2) nuclear pleomorphism, hyperchromatism, and an abnormal nuclear-cytoplasmic ratio, 3) areas of increased cellularity with disorganization of the architecture, and 4) tumor necrosis. In contrast, typical carcinoid tumor may have focal cytologic pleomorphism, but necrosis is absent and mitotic figures are rare. Recently we experienced a case of atypical bronchial carcinoid with multiple distant metastasis, so we report this case with a review of the literature.

• 한국산업정보학회논문지
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• 제24권5호
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• pp.65-76
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• 2019

본 연구는 소비자가 지각하는 디자인 개성 차원이 제품 디자인의 태도나 구매의도 등 소비자 반응에 미치는 영향을 살펴보고 디자인 전형성이 디자인 개성과 소비자 반응간의 관계를 조절하는지를 검증하였다. 연구결과 전형적 디자인에 노출될 경우 진실성과 강인함이라는 디자인 개성 차원을, 비전형적 디자인에 노출되는 경우에는 열정과 세련됨 디자인 개성차원을 보다 높게 지각하는 것으로 나타났다. 전형적 디자인의 경우 진실성, 유능함, 열정, 강인함 등의 디자인 개성차원이, 비전형적 디자인의 경우에는 진실성, 유능함, 열정, 세련됨 등이 디자인 태도에 긍정적인 영향을 미치는 요인으로 나타났다. 또한 전형적 디자인의 경우에는 유능함과 강인함이, 비전형적 디자인의 경우에는 진실성, 열정, 강인함이 구매의도에 긍정적인 영향을 미치는 것으로 나타났다. 마지막으로 유능함과 강인함은 전형적 디자인에서, 세련됨은 비전형적 디자인의 경우 디자인 태도에 더 많은 영향을 미치는 것으로 나타났다. 또한 유능함은 전형적 디자인의 경우에, 열정은 비전형적 디자인에서 제품구매의도에 더 많은 영향을 주는 것으로 나타났다.