• Title/Summary/Keyword: Atypical

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Studies on partial characteyization and pathogenicity of atypical Aeronionas salmonicida EL-I isolated from diseased cultrued Eel (뱀장어에서 분리한 불정형 Aeromonas salmonicida EL-I의 일부 특성과 병원성에 관한 연구)

  • 한규삼;최인열;배정준;신성일;김영진;김영길;이근광
    • Korean Journal of Veterinary Service
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    • v.18 no.1
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    • pp.22-32
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    • 1995
  • A partial characteristics and pathogenicity of Aeromonas salmonicida strain isolated from diseased cultured eel were studied. On the biochemicial characteristics of the isolate strain was classified into atypical Aeromonas salmonicida : the characteristics of the isolate strain differed from those of the subspecies of Achromogenes, masoucida and salmonicida. It strain was named atypical Aeromonas salmonicida EL-1 and it grew at optimal pH 7.5 and l% Nacl. In the pathogenicity test, at one to two days post infection, the motality of artificially infected eels with $1{\times}10^8$ and $1.0{\times}10^7$ cfu/fish group was 100%, and at three days pos-infection, in the $1.0{\times}10^6$ /cfu /fish infected group, the epizootic haemorrhagic ulcer was developed, and haemorragic red sports were formed around abdomen and fins and its died (40%). Total cell protein peptide bands of the A. salmonicida EL-1 were presented betweeon 11.8~102 Kd in molecular weight by the electrophoretic analysis and appeared 28 bands in all. Drug sensitivity of atypical A. salmonicida EL-1 strain was sensitivity to chlorampenicol, gentamicin, kanamycin, streptomycin and sulfamethoxazole /trimethoprim and intermidiate to ampiclin and neomycin resistant to cephalotin, erythromycin, lincomycin and tetracycline.

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Atypical Trigeminal Neuralgia : Case Report (비정형 삼차신경통의 치험례)

  • Lee, Dong-Sik;Hong, Jung-Pyo
    • Journal of Oral Medicine and Pain
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    • v.25 no.2
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    • pp.229-234
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    • 2000
  • The patient, 62-years-old woman, had a constant dull pain in the right mandible and an intermittent spontaneous burning sensation of the mouth. The pain began 6 months ago. About 5 years ago, a trauma in her right mandible which was so severe that kept her in the hospital for 2 days. This was followed by mouth opening disturbance with pain for about 2 years. However, she did not have a treatment for the temporomandibular disorder symptoms. After then, she experienced the trigeminal neuralgia characterized by an electrical pain which lasted about 30 minutes in her right face and head when touching the skin or hair. After taking a year course treatment of trigeminal neuralgia, the symptom disappeared. The pain was a constant dull pain and a intermittent burning pain which are contradictory. And the pain responded to various modalities such as physical therapy, anti-inflammatory drug, carbamazepine, and amitriptyline, among which carbamazepine was most effective. The diagnosis was clinically made as an atypical trigeminal neuralgia. The term 'atypical' is used when there is something unknown and the problem is not identified. It is thought that an atypical pain may be approached in the perspective of chronic pain, neuropathic pain, and myofascial pain, the mchanisms of which are poorly understood. As the knowledge of pain physiology improves, there needs to be modification and re-evaluation. Pain disorders must be classified on the basis of an understanding of the underlying mechanism and etiology.

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A Study on the Correlation between Atypical Form Factor-based Smartphones and Display-dependent Authentication Methods (비정형 폼 팩터 기반 스마트폰과 디스플레이 의존형 사용자 인증기법의 상관관계 연구)

  • Choi, Dongmin
    • Journal of Korea Multimedia Society
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    • v.24 no.8
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    • pp.1076-1089
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    • 2021
  • Among the currently used knowledge-based authentication methods for smartphones, text and graphic-based authentication methods, such as PIN and pattern methods, use a display unit and a touch function of the display unit for input/output of secret information. Recently released smartphone form factors are trying to transform into various forms, away from the conventional bar and slate types because of the material change of the display unit used in the existing smartphone and the increased flexibility of the display unit. However, as mentioned in the study of D. Choi [1], the structural change of the display unit may directly or indirectly affect the authentication method using the display unit as the main input/output device for confidential information, resulting in unexpected security vulnerabilities. In this paper, we analyze the security vulnerabilities of the current mobile user authentication methods that is applied atypical form factor. According to the analysis results, it seems that the existing display-dependent mobile user authentication methods do not consider emerging security threats at all. Furthermore, it is easily affected by changes in the form factor of smartphones. Finally, we propose countermeasures for security vulnerabilities expected when applying conventional authentication methods to atypical form factor-based smartphones.

The Development of Behavioral Modification Program on Weight Reduction in Overweight Patients taking Atypical Antipsychotics - Preliminary Study - (비정형 항정신병약물 복용 중인 과체중 환자에서 체중 감량을 위한 행동수정요법의 개발 - 예비연구 -)

  • Shin, Hong Beom;Park, Jong Ho;Cha, Bo Seok;Kim, Byung Soo;Lee, Suk Kyung;Kim, Hak Lyung;Kim, Yong Sik;Ahn, Young Min;Kang, Ung Gu
    • Korean Journal of Biological Psychiatry
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    • v.10 no.2
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    • pp.186-196
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    • 2003
  • Objects:The authors devebped a behavioral modification program for oveweight outpatients with schi-zophrenia and bipolar disorder will had teen treated with atypical antipsychotics, and evaluated the applicability of this program to outpatients Methods:Two men and nine women who had been treated with atypical antipsychotics and will had gained at least 5 percent of their pre-treatment body weight for 10 weeks, attended a behavioral modification program. The patients' weight, body mass index and the diet-activity scale were assessed and were compared with those of a matched comparison group will dd not attend the behavioral modification program Results:The body weight of patients who attended the behavioral modification program reduced with statistical significance, The treatment group showed significant improvement in diet-related items but not in activity-related items of the diet-activity scale Conclusions:This study suggested the applicability of a eehavioral mcdification program on weight reduction to overweight patients taking atypical antipsychotics for the frrst time in Korea Additional large scale studies are needed to validate the effectiveness of this program.

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A Basic Study on the Possibility of Smart Mobile Application Development for Creating Education and Concepture Design Atypical Architectural Forms (비정형 건축의 정보 및 학습을 위한 스마트 모바일 애플리케이션 개발 가능성에 관한 기초 연구)

  • Park, Sang-Jun
    • The Journal of the Korea Contents Association
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    • v.17 no.8
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    • pp.14-26
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    • 2017
  • With the development of computer technology, many different kinds of digital design tools have been developed and used. In the circumstance, methodologies of digital process have more been researched. Despite various atypical forms, there have been limits to the application and practical use of the mobile technology for approaches to the creation of architectural forms and various circumstances. Therefore, this study tries to analyze previous studies and actual conditions of mobile application in order to recognize the research necessity and suggest the possibility of the atypical form creation in the mobile environment. In short, the purpose of this study is to recognize the necessity of the smart mobile application for making idea & learning tools, suggest the process based selective application method (not analytical application) of smart mobile application technology to make possible atypical form creation in the initial step of architectural design processes, and propose a new method of mobile application.

Prognostic Factors of Atypical Meningioma : Overall Survival Rate and Progression Free Survival Rate

  • Lee, Jae Ho;Kim, Oh Lyong;Seo, Young Beom;Choi, Jun Hyuk
    • Journal of Korean Neurosurgical Society
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    • v.60 no.6
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    • pp.661-666
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    • 2017
  • Objective : Atypical meningioma is rare tumor and there is no accurate guide line for optimal treatment. This retrospective study analyzed the prognostic factors, the effect of different methods of treatments and the behavior of atypical meningioma. Methods : Thirty six patients were diagnosed as atypical meningioma, among 273 patients who were given a diagnosis of meningioma in the period of 2002 to 2015. Age, gender, tumor location, Ki 67, Simpson grade and treatment received were analyzed. We studied the correlation between these factors with recurrence, overall survival rate and progression free survival. Results : Median overall survival time and progression free survival time are 60 and 53 (months). Better survival rate was observed for patients less than 50 years old but with no statistical significance (p=0.322). And patients with total resection compared with subtotal resection also showed better survival rate but no statistical significance (p=0.744). Patients with a tumor located in skull base compared with patients with a tumor located in brain convexity and parasagittal showed better progression free survival (p=0.048). Total resection is associated with longer progression-free survival than incomplete resection (p=0.018). Conclusion : We confirmed that Simpson grade was significant factor for statistically affect to progression free survival in univariate analysis. In case of skull base atypical tumor, it is analyzed that it has more recurrence than tumor located elsewhere. Overall survival was not affected statistically by patient age, gender, tumor location, Ki 67, Simpson grade and treatment received in this study.

Evaluation of "Atypical Squamous Cells of Undetermined Significance" by the Bethesda System (Bethesda system에 의한 "atypical squamous cells of undertermined significance"의 평가)

  • Kim, Yee-Jeong;Hong, Sung-Ran;Kim, Hy-Sook;Park, Jong-Sook;Kim, Kye-Hyun;Lim, Kyung-Ho;Shim, Jae-Uk;Park, Chong-Taik;Chun, Chong-Soo
    • The Korean Journal of Cytopathology
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    • v.4 no.2
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    • pp.81-86
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    • 1993
  • The recently proposed Bethesda system for cervical/vaginal cytology has made a standardization related to "atypia". In cellular changes due to inflammation or repair, the word "benign cellular change" has been suggested as a substitute for atypia. Terminology related to atypical cells may become standardized, but the cytologic criteria has not been well defined yet. We evaluated 160 cases of atypical squamous cells of undetermined significance(ASCUS) by the Bethesda Sys4em(TBS). Among 30,428 cases screened, a cytologic diagnosis of ASCUS was made in 498 cases(1.6%) and 160 cases were histologically verified ASCUS was diagnosed based on nuclear enlargement and nonclassical signs of condyloma. The results are as follows: One hundred and twenty three cases(76.9%) revealed chronic cervicitis. Thirty seven cases(23.1%) demonstrated squamous intraepithelial lesion. Among intraepithelial lesions, condyloma and mild dysplasia were 28 cases(75.7%). Moderate and severe dysplasia were 5 cases(13.5%) and 4 cases(10.8%), respectively. it is concluded that patients with ASCUS should be colposcopically examined.

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Qualification of Atypical Squamous Cells of Undetermined Significance - "ASCUS, R/O HSIL" : Cytologic Features and Histologic Correlation (자궁경부 세포진에서 ASCUS 진단의 세분화 - "ASCUS, R/O HSIL" : 세포학적 소견 및 조직학적 상관성)

  • Kim, Hye-Sun;Kim, Bock-Man;Kim, Yee-Jung;Kim, Hy-Sook
    • The Korean Journal of Cytopathology
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    • v.13 no.1
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    • pp.14-20
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    • 2002
  • Cytologic and histopathologic features and human papillomavirus (HPV) DNA detection associated with 101 cervicovaginal smears which are ciassified as 'atypical squamous cells of undetermined significance, rule out high grade squamous intraepithelial lesion(ASCUS, R/O HSIL)' were reviewed and compared to 89 smears of 'ASCUS, not otherwise specified(NOS)'. Cytologic fieatures of ASCUS, R/O HSIL included atypical single small cells(36.6%), hyperchromatic tissue flagments(35.6%), atypical metaplastic cells(18.8%), endometrial cell-like clusters(5.9%), and atypical parakeratotic cells(3.0%). A final diagnosis of HSIL on biopsy was assigned to 47(54.0%) of 87 women with ASCUS, R/O HSIL and to 13(14.6%) of 89 women with ASCUS, NOS (p=0.000). There was no difference in HPV DNA detection late between ASCUS, R/O HSIL and ASCUS, NOS smears. These data suggest that subclassification of ASCUS is helpful to manage patients because ASCUS, R/O HSIL is more often associated with an underlying HSIL on biopsy. Therefore, women with ASCUS, rule out HSIL should be actively managed with colposcopic examination.

A Case of atypical bronchial carcinoid with multiple distant metastasis (다발성 원격전이를 보인 비정형 기관지 유암종 1예)

  • Lee, Tae-Hun;Yang, Sung-Uk;Lee, Tae-Kwan;Kim, Byung-Koo;Kim, Ji-Young;Kim, Kwi-Wan;Lee, Kwang-Min
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.3
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    • pp.440-448
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    • 1996
  • Bronchial carcinoid tumors are uncommon, constituting approximately 3-5% of all primary lung cancers. Classification of these tumors has evolved substantially as our understanding of the cellular, biologic, and clinical aspects of these neoplasms has improved. Initially, bronchial carcinoids were thought to be benign and therefore were classified as bronchial adenomas. Currently, however, they are well recognized as having the potential for both local invasion and distant metastatic involvement. Consequently, carcinoid tumors are frankly malignant. Thus bronchial adenoma is a misnomer that should no longer be used for bronchial carcinoids. Most investigators currently favor classifying carcinoid tumors as a type of neuroendocrine neoplasm because of their potential to secrete a variety of chemical substances found in both the central nervous system and the epithelial cells of numerous organs. Bronchial carcinoids are usually characterized by a slow growth pattern and a low incidence of metastasis, and histologically conformed by the azurophil staining and the presence of the characteristic neurosecretary granule on electron microscopy. Atypical carcinoid tumor was first defined by Arrigoni et al, who proposed the following criteria for separation of atypical carcinoid from typical carcinoid tumor : 1) increased mitotic activity with 1 mitotic figure per 1-2 high power fields(or 5-10 mitoses /10 HPF), 2) nuclear pleomorphism, hyperchromatism, and an abnormal nuclear-cytoplasmic ratio, 3) areas of increased cellularity with disorganization of the architecture, and 4) tumor necrosis. In contrast, typical carcinoid tumor may have focal cytologic pleomorphism, but necrosis is absent and mitotic figures are rare. Recently we experienced a case of atypical bronchial carcinoid with multiple distant metastasis, so we report this case with a review of the literature.

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The Effect of Design Personality on the Relationship between Design Personality and Consumer Response (디자인 개성과 소비자 반응 간의 관계에 대한 디자인 전형성 효과)

  • Na, Kwang Jin
    • Journal of Korea Society of Industrial Information Systems
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    • v.24 no.5
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    • pp.65-76
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    • 2019
  • This research examines the effects of perceived design personality on consumer responses such as attitude toward products and purchase intention. Furthermore, the study analyzes if the design typicality moderates the effects of design personality on consumer responses. The research results found that when consumers are exposed to a typical design, they are more likely to perceive sincerity and ruggedness at a higher level. On the other hand, consumers tend to perceive a higher level of excitement and sophistication, as they are exposed to the atypical design. Besides, competence and ruggedness have positive effects on buying intention in the case of a typical design, while sincerity, excitement, and sophistication have positive impacts on buying intention in the case of an atypical design. Lastly, competence and ruggedness are found to have positive impacts on design attitude more in the typical design than in the atypical design, whereas sophistication showed positive impacts on design attitude more in the atypical design than in the typical design. Additionally, competence has more influence on product buying intention in the typical design and excitement has more effect on it in the atypical design.