• 대한한의학원전학회지
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• 제27권3호
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• pp.141-154
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• 2014

Objectives : This study was fulfilled in order to support the hypothesis which atopic dermatitis can be treated better by therapy of liver rather than of spleen and stomach from the view point of Korean Medicine, or not. Methods : From October to December in 2013, 12 children from elementary school participated in this therapy and prevention program. We divided into 3 degrees, for example, light, moderate, and severe symptoms. They were treated by 3 step therapy consisted of detoxification, treatment, and supplement to both Qi and blood. Results : After 3 months of therapy, we discovered that their symptoms had been improved to 11 among 12 children(91.7%). Conclusions : From the result, we verified the hypothesis atopic dermatitis can be treated better by therapy of liver rather than of spleen and stomach in Korean Medicine.

• 대한한의학회지
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• 제39권3호
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• pp.81-88
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• 2018

Objectives : This study was performed1 to assess the effectiveness of HwangryunHaedokTang-gamibang on Obesity with atopic dermatitis. Methods : Patients were treated by HwangryunHaedokTang-gamibang. To measure treatment outcomes, BMI, weight, Fat mass, Fat %, VAS scale, SCORAD index were used. Results : After treatment, BMI, weight, Fat mass, Fat% were significantly decreased. Atopic dermatitis VAS and SCORAD index were also decreased at all cases. Conclusions: HwangryunHaedokTang-gamibang may be effective in the treatment of Obesity with atopic dermatitis patients.

• 대한한방소아과학회지
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• 제21권2호
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• pp.169-184
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• 2007

Objetives The late research tendency on atopic dermatitis is mainly focused on the experiment of unbalance of cytokine released from T cell subtype. Merhods As there's no experiment with herbal medicine using Hanghaedan(HHD), we isolated and cultured monocytes of atopic dermatitis pateints (AD) peripheral blood, for knowing the influence of HHD on the secretory function of IL-4, IL-5, $IFN-{\gamma}$. Results 1. In AD group, HHD exhibits statistically significant inhibitory effect on IL-4(p<0.05). 2. In AD group, HHD exhibits statistically significant inhibitory effect on IL-5(p<0.05). 3. In AD group, HHD exhibits statistically significant inhibitory effect on $IFN-{\gamma}$ (p<0.01). 4. Sample group comparing with the cytokine concentration rate value of AD patients and that of NAD patients IL-4 of AD patients exhibits statistically significant decrease(p<0.05). 5. In AD group, there is no significant relation between serum IgE and cytokines. 6. In AD group, there is no significant relation between total eosinophil and IL-5. Conclusions Effects of Hanghaedan on the cytokine(IL-4, IL-5, $IFN-{\gamma}$) secretory function of monocytes of atopic dermatitis patients is recognized.

• 대한한방소아과학회지
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• 제14권1호
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• pp.137-152
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• 2000

The purpose of this study was on effect of Bopejungcheuntang(BPJC) for atopic dermatitis. During 5 months between January and May 2000, BPJC water extract administered to patient suffering from atopic dermatitis, in Dep. of Pediatrics, Dongguk university Pundang Oriental Hospital and this study was conducted for 27 patient (male 17, female 10) The result were as follows 1. The distribution of remedial values were improvement (51.9%), unresponsiveness(37.0%), depravation(11.1%). 2. After dispensing BPJC, ordinal sites of atopic dermatitis were inner space of elbow and knee joint, face and neck, back and abdomen, wrist and ankle. Befor and after dispensing BPJC this ordinal sites were similar but after dispensing BPJC, the other sites except head is improved. Order of symptomatic improvement is itching, licheniasis, erythema, exudate. Both itching and exudate is significantly improved. 3. According to way of water extract, symptomatic improvement is most excellent with general water extract & distiled water, the second is general water extract, the third is distiled water. 4. BPJC effect on atopic dermatitis is not significantly affected by sex, day of falling ill, medical treatment, resident environment, feeding, character and duration of medical treatment.

• 한국콘텐츠학회논문지
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• 제15권9호
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• pp.342-350
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• 2015

본 연구는 아토피 피부염을 가진 여대생을 대상으로 Van Manen의 해석학적 현상학적 연구방법을 적용하여 생활 체험의 의미와 본질이 무엇인지 이해하고자 하였다. 총 9명의 참여자를 심층 면담하여 생활과 관련된 본질적 주제를 신체성, 관계성, 시간성, 공간성의 4개의 실존체에 따라 나타났다. 참여자들은 여성으로서 부정적이며 감추고 싶어 하는 자신의 몸을 고통으로 체험하였으며 타인의 시선으로 자책감과 지지 받지 못하는 관계성을 나타냈다. 홀로 고립하는 것이 안전한 공간성을 나타내고 아토피 피부염을 가진체로 살아가는 시간이 부담이 되는 독특한 생활 체험하게 된다. 본 연구 결과 아토피 피부염을 가진 여대생의 체험에 근거하여 통찰력을 제공함으로써 생활세계에 대한 공감적 이해와 지지를 통해 참여자와 그들의 가족들에게 실제적 도움이 될 수 있을 것이다.

• 대한한방소아과학회지
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• 제26권2호
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• pp.53-61
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• 2012

Objectives To make comprehensive feature of clinical trials using herbal medicine and their results by today, then help a strategy for herbal medication-derived clinical studies in the future. Methods Through medical website (Pubmed EBSCO Medline), foreign clinical literatures about atopic dermatitis and herbal medicine were searched. And domestic clinical literatures about atopic dermatitis using internet website (OASIS) and hand-searching. Analysis was performed according to distribution mainly by subject, study design, number by year and its efficacy. Results and Conclusions Seventy-nine (Domestic literatures: Fifty, Foreign literatures: Twenty-nine) literatures were selected according to inclusion criteria of clinical study. 80% of domestic clinical literatures were observational studies, 50% of foreign were intervention. There were six adverse effect case studies, two follow-ups, one case report, four translational and four uncontrolled clinical trials in foreign literatures. And nineteen case reports, eighteen case series, two follow-up and five uncontrolled clinical studies in domestic. Six RCTs have established by four external herb therapy and two decoctions in Korea, showed positive effects. Three out of four external applications RCTs, four out of seven decoctions showed positive results in foreign studies. This study revealed the current status of atopic dermatitis clinical research using herbal drugs. To put clinical trials to use of herbal medicine in the treatment atopic dermatitis, scientific and objective-based studies should be needed.

• 부모자녀건강학회지
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• 제19권1호
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• pp.9-16
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• 2016

Purpose: The disease specific self-efficacy of mothers caring children with atopic dermatitis is a crucial factor for adherence to recommended treatments. This study investigated factors associated with disease specific self-efficacy of mothers of atopic dermatitis children. Methods: A cross-sectional study was used. One hundred twenty five mothers recruited from the out-patient clinic of three hospitals completed self-administrative questionnaires, including the disease specific self-efficacy, general parenting efficacy, and severity of atopic dermatitis. Descriptive statistics, ANOVA, and multiple regression analysis were performed. Results: The degree of disease specific self-efficacy of mothers was significantly different according to the disease severity, and parenting efficacy. 26.0% of the variance of disease specific self-efficacy was explained by the severity of disease and parenting efficacy. Conclusions: Future studies need to focus on the development of educational programs that will help to improve mothers' disease specific self-efficacy as well as parenting efficacy.

• 한방안이비인후피부과학회지
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• 제28권1호
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• pp.68-84
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• 2015

Object : The object of this study was effected of composed of 4 herbal medicines(Rubus coreanus, Rehmanniae Radix, Houttuynia cordata, Betulae cortex) on acute atopic dermatitis mice. Methods : BALB/c mice were divided 4 groups ; normal group, negative control group of acute atopic dermatitis mice induced by DNCB, treated apply to the back skin with the herbal medicine group, and treated orally with herbal medicine group. Treated with herbal medicine and DNCB during 2 weeks. After treated, measured WBCs, RBCs, and platelet in the blood, and analysed mRNA expression of spleen. Result : Composed herbal medicines could reduce WBCs, lymphocytes, monocytes, neutrophils, and eosinophils in the mouse blood. And, could down TNF-${\alpha}$ levels in spleen. In the skin tissue histology results, herbal medicines reduce the cells and T cells. Conclusion : Composed herbal medicines help to another inflammatory disease because they reduce the cells and T cells in the skin tissues. And they have inhibitory effects of TNF-${\alpha}$ mRNA expression, and Th 2 immune responses. Therefore herbal medicines use for an acute atopic dermatitis treatment.

• 지역사회간호학회지
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• 제26권3호
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• pp.230-237
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• 2015

Purpose: This study aimed to assess the prevalence of asthma, allergic rhinitis, and atopic dermatitis in elementary school students according to the body mass index. Methods: This study was conducted as cross-sectional descriptive research using a structured questionnaire. Data were collected from 6,398 students at 15 elementary schools located in Y City in Korea. The cross-sectional survey used the Korean version of International Study of Asthma and Allergies in Childhood questionnaire. Logistic regression analysis was performed to estimate the odds ratios of body mass index. Results: The symptom prevalence of asthma, allergic rhinitis, and atopic dermatitis in the last 12 months was 12.4%, 49.5%, and 24.5%, respectively. The symptom prevalence of asthma was significantly higher in the obesity group. The number of those without any asthma symptom in lifetime was significantly smaller in the overweight (OR=0.70, p=.004) and obesity (OR=0.57, p=.005) groups than in the healthy weight group. Conclusion: These results suggest that asthma, allergic rhinitis, and atopic dermatitis prevention programs for elementary school students should include weight control intervention.

• 한국콘텐츠학회논문지
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• 제8권11호
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• pp.242-250
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• 2008

아토피 피부염은 그 증상이 심각하고 그와 더불어 환자의 심리적 상태도 통제할 수 없을 정도로 황폐화되는 난치성 질환이다. 최근 연구보고들에 따르면 이 질환에 스트레스와 같은 심리적 요인이 중요하게 작용하며, 심리적 문제를 치료하는데 사용되는 기법들이 이 질환에도 유효하게 작용한다고 한다. 따라서 여기에서는 심리적 스트레스를 완화시켜 다양한 정신신체질환을 예방하고 치료하기 위한 목적으로 널리 사용되는 심신의학 프로그램을 아토피 질환의 추가적 치료 수단으로 제안하였다. 또한 심신의학 프로그램 의 치료 효과 모형과 치료자가 갖추어야 할 요건에 대해서도 논의하였다.