• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.655-661
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• 2004

Anorexia nervosa is a serious, often chronic, and life-threatening eating disorder defined by a refusal to maintain minimal body weight (within 15% of an individual s normal weight). Other essential features of this disorder include an intense fear of gaining weight, a distorted body image, and amenorrhea(absence of at least three consecutive menstrual cycles when they are otherwise expected to occur). With anorexia nervosa, the nails and hair become brittle, and the skin may become dry and yellow. In addition to depression, hypothermia, lanugo, nausea, vomiting, anxiety and dehydration from sweating can appear. Starvation, weight loss, and related medical complications are quite serious and can result in death. Recently one patient was admitted with anorexia nervosa-like symptoms. The patient is a 18-year-old girl with complaints of weight loss, amenorrhea, anorexia, nausea, vomiting, tremor, and sweating. After treatment through oriental medicine for 2 weeks, most of the symptoms improved. Therefore, this application of oriental medicine is reported with a plea for further investigation.

• Korean Journal of Adult Nursing
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• v.15 no.4
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• pp.573-584
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• 2003

Purpose: This study was conducted to investigate the level of nausea & vomiting, anorexia and food intake during the periods of chemotherapy and 14 days after discharge. Method: The subjects were 40 cancer patients(cervix cancer : 20 patients, stomach cancer: 20 patients) who had chemotherapy with Cisplatin & 5-Fu. Data were analyzed by mean & standard deviation, ANCOVA. Result: 1. The severity of nausea & vomiting with anorexia in cancer patients receiving chemotherapy was the highest at the 3rd day and then it gradually decreased. At the 14th day after discharge, nausea & vomiting with anorexia still remained with very low levels. 2. The amount of food intake was the lowest on the 3rd day and then gradually increased. However, it was 53.3-72.5% of the ordinary food intake on the 14th day after discharge. Calorie intake was 625.31 Kcal on the 3rd day and 1130.92 Kcal on the 7th day after discharge. 3. There were no significant differences in nausea & vomiting, anorexia, food intake, calory intake between those with cervix cancer and stomach cancer. Conclusion: In cancer patients nausea & vomiting and anorexia were severe and food intake was very poor during chemotherapy but afterwards they were gradually improved, but were not completely recovered on the 14th day after discharge. Therefore the nursing intervention regarding the increase of food intake was necessary during chemotherapy and after discharge.

• The Journal of Pediatrics of Korean Medicine
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• v.36 no.1
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• pp.1-37
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• 2022

Objectives This study aimed to provide a basis for applying Korean medical treatment for childhood anorexia in clinical practice by examining Korean medical etiology, pattern differentiation, and treatment, and focusing on research articles on Chinese medicine. Methods Articles on Chinese medicine related to childhood anorexia published before November 4, 2021, in the China National Knowledge Infrastructure (CNKI), were analyzed. The etiology, pattern differentiation, and Chinese medical treatment were summarized. Results Of a total of 73 studies, 13 were randomized controlled trials (RCT), 32 were case studies, and 28 were review papers. The most common Chinese medical etiology of childhood anorexia was emotional instability, and the western medical etiology was problems with diet and lifestyle. The most frequently reported pattern differentiations were spleen-stomach-qi deficiency (脾胃氣虛), stomach-yin deficiency (胃陰不足), and spleen failing in transportation syndrome (脾失健運). The most frequent prescriptions were modified Yangwijeungaektang (养胃增液湯加減), Samryongbakchulsan (蔘苓白术散加减), and Ekongsan (異功散加減). As frequntly used tuina acupoints, Naepalgwae (内八卦), Joksamli (足三里), and Bigyeong (脾經) were mentioned. Conclusions This study analyzed the etiology, pattern differentiation, and Korean medical treatment of anorexia in children. Based on this study, standardization and well-designed clinical studies on Korean medical treatments for childhood anorexia can be expected in the future.

• The Journal of Korean Medicine
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• v.44 no.4
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• pp.26-40
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• 2023

Objectives: This study was to evaluate the effectiveness and safety of Bojungikgi-tang for lung cancer patients with anorexia. Methods: This was a single-arm, open-label, and single-center trial, and suitable participants took Bojungikgi-tang (Buzhongyiqi-tang in Chinese, Hochuekki-to in Japanese) three times a day before or between meals for six weeks (42 days). After registration of clinical trials (visit 2), they visited the hospital every three weeks (visits 3 and 4) and measured or tested the effectiveness or safety evaluation variables to analyze the results. The primary outcome was the anorexia/cachexia subscale (A/CS) of functional assessment of anorexia/cachexia therapy (FAACT) score. Results: Seventeen lung cancer patients were included in the intention-to-treat (ITT) analysis. Lung cancer patients had higher A/CS of FAACT scores after six weeks of Bojungikgi-tang administration compared to that at the baseline. This was not significant four lung cancer (p=0.1668). In the secondary outcomes, the visual analog scale (VAS) score of anorexia decreased significantly (p=0.0009), and the CD4/CD8 ratio (p=0.0396) and CD4 levels (p=0.0345) significantly increased after six weeks of treatment. No serious adverse events were reported with Bojungikgi-tang in lung cancer patients. Conclusions: Bojungikgi-tang can be an effective and safe treatment for anorexia in lung cancer patients undergoing chemotherapy.

• The Journal of Internal Korean Medicine
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• v.41 no.5
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• pp.769-776
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• 2020

Objective: This case study reports improvement in a case of Guillain-Barre Syndrome by Korean medicine treatment in a patient with quadriplegia and anorexia. Methods: A 79-year-old woman diagnosed with Guillain-Barre Syndrome was treated with acupuncture, electroacupuncture, Bojungikgi-tang-gami, cupping, moxibustion, and rehabilitation. Her clinical symptoms were measured with the Manual Muscle Test (MMT), Modified Barthel Index (MBI), Functional Independence Measurement (FIM), and the EuroQol five-dimensional descriptive system (EQ-5D-5L). Results: After treatment, improvements in the MMT, MBI, FIM, and EQ-5D-5L were observed and her anorexia decreased. Conclusion: Korean medicine treatment appeared to be effective in the treatment of a patient with Guillain-Barre Syndrome with quadriplegia and anorexia.

• Asian Oncology Nursing
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• v.10 no.1
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• pp.38-47
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• 2010

Purpose: The purpose of this study was to identify the effects of nutritional education program (NEP) on nausea and vomiting, anorexia, food intake, and nutritional status among GI cancer patients undergoing chemotherapy. Methods: A nonequivalent, non-synchronized posttest design was used. Study subjects were conveniently selected 30 patients (15 subjects for each group) who were undergoing chemotherapy. The subjects of the experimental group received NEP which consisted of 2 educations and 1 counselling while they were hospitalized, and telephone counselling with nutritional supports after discharge for four times. Results: The score of anorexia was lower and the amount of food intake was higher in the experimental group than those of the control group. However, there were no significant differences in levels of nausea and vomiting, weight, hemoglobin, albumin, and total protein level between the experimental and the control group. Conclusion: The findings demonstrate that the NEP was effective in alleviating anorexia and improving subjective food intake of GI cancer patients undergoing chemotherapy. These findings suggest that NEP can be a useful nursing intervention for preventing nutritional disorders for patients with GI cancer after chemotherapy.

• Anxiety and mood
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• v.3 no.2
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• pp.69-76
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• 2007

Anorexia nervosa is a physical and psychosocial disorder that occurs most frequently in adolescent girls and young adult women. A decade ago, anorexia nervosa was rare outside of the developed western countries. However, it is now becoming a common clinical problem among young women in Korea. It is not enough to merely focus on relieving patients from the symptoms of "not eating," which is a practice that has been adopted by some forms of hospital care. The evidence base to guide treatment is limited. Nevertheless, there is the hope that a better understanding of the factors that play a role in the initiation and maintenance of disordered eating behaviors may be lead to more sophisticated treatments. This review aims to look beyond the overt "not eating" phenotype of anorexia nervosa and considers eating disorder endophenotypes based on Treasure's model. The first part of the review sets the basis for a framework of potential eating disorder endophenotypes. A description of the evidence of disordered eating behaviors as well as the clinical and psychopathological features associated with the central control of appetite follow. Finally, we describe how endophenotypes can be translated into treatments.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.3
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• pp.97-107
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• 2016

Objectives The purpose of this study is to investigate recent clinical studies on the effect of external therapy for infantile anorexia. Methods We searched for the study at CNKI by a keyword 'xiaoaryanshizheng' after 2010. 40 clinical studies which were using one external therapy method were selected. Result Selected 40 clinical studies were divided into six types of external therapy. The subjects for these clinical studies were between three months and 14 years old children. The number of the subjects was between 20 and 260. The period of treatment was between three days and three months. Only using one external therapy for infantile anorexia had 84.62%-100% cure rate. Conclusions Based on these clinical studies, external therapy has been shown as an effective treatment on infantile anorexia.

• Korean Journal of Hospice Care
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• v.4 no.2
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• pp.42-51
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• 2004

Purpose: The purpose of this study was to examine the effects of aroma oil inhalation using peppermint and bergamot on nauseaㆍvomiting and anorexia in cancer patients receiving chemotherapy. Method: Study subjects were 30 patients who had experienced nausea and vomiting when they had been hospitalized in K university hospital located in D city to receiving more than two Cisplatin combination chemotherapy. Among them 15 patients were in the experimental group doing aroma oil inhalation and the other 15 patients were in the control group without aroma oil inhalation. The data were collected from February 1, 2002 to May 17, 2002. The data were collected from February 1, 2000 to May 17, 2002. The data were analyzed with SPSS WIN 10.0 program using frequency, percentage, X2-test, t-test, Repeated Measures ANOVA. Result: 1)The degree of nauseaㆍvomiting on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. 2)The degree of anorexia on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. Conclusion: aroma oil inhalation was effective for relieving patients' nauseaㆍvomiting and anorexia receiving chemotherapy. Therefore, it is proposed that aroma oil inhalation should be applied as a supportive nursing arbitration method to relieve patients' nauseaㆍvomiting and anorexia who are receiving chemotherapy.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.793-799
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• 2021

Objectives: This study examined the effects of Gamisachil-tang on an anorexic patient with depression. Methods: A patient suffering from anorexia and depression was treated with Korean herbal medicine (Gamisachil-tang) for 14 days. To evaluate the therapeutic effect, we measured the daily food intake of the patient and used the Visual Analogue Scale (VAS) for anorexia. Results: Following treatment, both the patient's daily food intake of the patient and VAS score for anorexia had improved. Conclusion: These results suggest that Gamisachil-tang has a beneficial effect on both anorexia and depression.