• Journal of Microbiology and Biotechnology
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• 제29권10호
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• pp.1603-1606
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• 2019

Sortase A (SrtA), a type of transpeptidase responsible for anchoring surface proteins to the peptidoglycan cell wall, is important in the virulence of gram-positive bacteria. Three compounds were isolated from marine-derived Streptomyces sp. MBTH32 using various chromatography techniques. The structures of these compounds were determined based on spectroscopic data and comparisons with previously reported data. Among the metabolites tested, lumichrome showed strong inhibitory activity against Staphylococcus aureus SrtA without affecting cell viability. The results of cell clumping activity assessment suggest the potential for using this compound to treat S. aureus infection by inhibiting SrtA activity.

• Structural Engineering and Mechanics
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• 제88권3호
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• pp.251-262
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• 2023

This paper presents a method for assessing the dynamic responses of gravity-based structures (GBS) under various seismic loads, with a focus on fluid-structure-ground interactions. Models of GBSs and their surrounding environments were developed, incorporating interaction effects among the structure, seawater, and seabed. Dynamic responses of the GBS subjected to three seismic loads-Chi-Chi, Northridge01, and Northridge02-were calculated, with consideration of both horizontal and vertical accelerations, as well as displacements. Parametric studies indicated that the primary factors affecting the dynamic responses of GBS were seismic loads characterized by significant input forces and accelerations. The frictional force on the ground had minimal impact on the horizontal and vertical displacements of the GBS. Weight emerged as a critical factor in anchoring the GBS to the ground and minimizing vertical accelerations and displacements.

• Coupled systems mechanics
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• 제13권4호
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• pp.293-310
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• 2024

This paper investigates the dynamic response of structures during earthquakes and provides a clear understanding of soil-structure interaction phenomena. It analyses various parameters, comprising ground shear wave velocity and structure properties. The effect of soil impedance function form on the structural response of the system through the use of springs and dashpots with two frequency cases: independent and dependent frequencies. The superstructure and the ground were modeled linearly. Using the substructure method, two different approaches are used in this study. The first is an analytical formulation based on the dynamic equilibrium of the soil-structure system modeled by an analog model with three degrees of freedom. The second is a numerical analysis generated with 2D finite element modeling using ABAQUS software. The superstructure is represented as a SDOF system in all the SSI models assessed. This analysis establishes the key parameters affecting the soil-structure interaction and their effects. The different results obtained from the analysis are compared for each studied case (frequency-independent and frequency-dependent impedance functions). The achieved results confirm the sensitivity of buildings to soil-structure interaction and highlight the various factors and effects, such as soil and structure properties, specifically the shear wave velocity, the height and mass of the structure. Excitation frequency, and the foundation anchoring height, also has a significant impact on the fundamental parameters and the response of the coupled system at the same time. On the other hand, it have been demonstrated that the impedance function forms play a critical role in the accurate evaluation of structural behavior during seismic excitation. As a result, the evaluation of SSI effects on structural response must take into account the dynamic properties of the structure and soil accordingly.

• 대한치과의사협회지
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• 제48권11호
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• pp.829-840
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• 2010

In recent years, medical techniques have provided patients with various measures to improve their quality of life. For dental treatment, drug-mediated sedation techniques for relieving dental anxiety have been developed, but behavior control through drugmediation may be limited because of possible side effects, contraindications, and the additional expense to the patient. Many patients tend to avoid the treatment or are unwilling to accept it and this makes both patients and dentists feel pressured. The field of NLP application might alleviate this uncomfortableness. Recently, NLP has spread to the dental and medical field rapidly and has been used in surgical treatments as well as in direct psychotherapy. NLP techniques which could be applied to dental phobic patients are as follows. 1) anchoring, 2) dissociation, 3) submodality change, 4) time line threapy, 5) swish pattern, 6) six step reframing, 7) parts integration, 8) modeling and imagination and so on. The aim of this study is to examine the strategy of NLP psychology so that dental phobic patients can be treated efficiently and effectively by the application of behavior management. Through NLP, patients can be induced to have more positive attitudes and experiences in future dental treatment.

• 한국경영과학회지
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• 제21권3호
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• pp.109-125
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• 1996

Biases and errors in the human being's reasoning process have been studied continuously by the researchers, especially psychlogists and social scientists. These bias phenomenon is classified on the basis of the origin, i. e. motivation and cognition. Furthermore the necessity of research on the bias in the management and management information system areas in increased more and more recently, which have their academic backgrounds in the psychology and social science. The biased information stream is transformed into the systematic error due to the motivation and cognitive bias of human-being, then its resulting phenomena are as follows; 1. the availability of salient information 2. preconceived ideas or theories about peoples and event 3. anchoring and perseverence phenomena. In order to reduce the information errors, Satty suggested the Analytic Hierarchy Process (AHP) that is the subject of this paper and that is widely used for evaluation of complex decision making alternatives. THerefore this paper studies AHP's effects and its limitations in applying to the management area. Thus this paper compared the performances of the 3 models : 1 the traditional additive regression model. 2 regression model using the factor score, and 3 the regression model with AHP. As a result, 3 models produce the different outcomes.

• The Korean Journal of Physiology and Pharmacology
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• 제9권1호
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• pp.9-15
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• 2005

We attempted to analyze the mechanism of polychlorinated biphenyl (PCB)-induced neurotoxicity and identify the target molecules in the neuronal cells for PCBs.Since the developing neuron is particularly sensitive to PCB-induced neurotoxicity, we isolated cerebellar granule cells derived from 7-day old Sprague Dawley (SD) rats and grew cells in culture for additional 7 days to mimic PND-14 conditions. Only non-coplanar PCBs at a high dose showed a significant increase of total protein kinase C (PKC) activity at phobol 12,13-dibutyrate ([$^3M$]PDBu) binding assay, indicating that non-coplanar PCBs are more neuroactive than coplanar PCBs in neuronal cells. PKC isozymes were immunoblotted with the selected monoclonal antibodies. PKC-${\alpha}$, ${\delta}$, and ε were activated with non-coplanar PCB exposure. Receptor for activated C kinase-1 (RACK-1), anchoring protein for activated PKC, was more induced with exposure to coplanar PCBs than non-coplanar PCBs. Reverse transcription PCR (RT-PCR) analysis showed induction of neurogranin (RC-3) and growth associated protein-43 (GAP-43) mRNA with non-coplanar PCBs. The results indicate that these factors may be useful biomarkers for differentiating non-coplanar PCBs from coplanar PCBs. The present study demonstrated that non-coplanar PCBs are more neuroactive congeners than coplanar PCBs.

• 한국표면공학회지
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• 제45권1호
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• pp.1-7
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• 2012

Multi-walled carbon nanotube (MWCNT) aluminum composite powders were deposited to form coatings using a high velocity oxygen fuel (HVOF) spraying process. High thermal energy and contact with atmospheric oxygen were supplied as the MWCNT aluminum composite particles were exposed to a gas flow field at high temperature (${\sim}3.0{\times}10^3$ K) during HVOF spraying. As a result, the particles underwent full or partial melting and rapid solidification due to the high thermal energy, and the exposure to oxygen induced the interfacial reaction of MWCNTs within the particle. The electrical and mechanical properties of MWCNT aluminum composite coatings were evaluated based on microstructure analysis. Electrical resistivity, elastic modulus, and micro-hardness, of the MWCNT aluminum composite coatings were higher than those of pure aluminum coating. The contribution of MWCNTs to the aluminum matrix can be attributed to their high electrical conductivity, dispersion hardening and anchoring effects. The relationship among the properties and the interaction of the MWCNTs with the aluminum matrix is discussed.

• Journal of Information Science Theory and Practice
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• 제8권2호
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• pp.18-31
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• 2020

Cognitive biases can influence human information behaviour and decisions made in information behaviour and use. This study aims to identify the biases involved in some aspects of information behaviour and the role they play in information behaviour and use. Twenty-five semi-structured face-to-face interviews were conducted in an exploratory qualitative study with graduate (MA and PhD) students who were at the stage of their dissertation/thesis research. Eisenberg & Berkowitz Big6^TM Skills for Information Literacy was adopted as a framework for interviews and the analysis was done using grounded theory coding method. The findings revealed the presence of twenty-eight biases in different stages of information behaviour, including availability bias (affects the preference for information seeking strategies), attentional bias (leads to biased attention to some information), anchoring effect (persuades users to anchor in special parts of information), confirmation bias (increases the tendency to use information that supports one's beliefs), and choice-supportive bias (results in confidence in information seeking processes). All stages of information seeking were influenced by some biases. Biases might result in a lack of clarity in defining the information needs, failure in looking for the right information, misinterpretation of information, and might also influence the way information is presented.

• 수산해양기술연구
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• 제32권2호
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• pp.132-147
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• 1996

The optimal design of floating type fisheries facilities in the open sea is demanded considering with the severe hydrodynamic forces on floating body, mooring tension and holding force of anchor. For conserving the facilities in most effective state, design and selection of anchor system is one of the most important fundamental subject. To enhance the design procedure of anchor system the holding forces of anchor are investigated by the hydraulic model test and are compared with the typical conventional results for various anchors. Applicability of previous estimation methods of holding force are checked and holding mechanism of anchor is discussed. Using the results a new computational concept of holding force is suggested considering mainly the effects of passive soil pressure (resistance), steady soil pressure, and surface friction etc. The new estimation method is proved as a feasible one by comparing the results of hydraulic model experiments. Applicability of various anchors to the anchor system on open sea fisheries structures is comprehensively reviewed using the present model tests and previous study results in the viewpoint of economy, construction and stability etc. Using the results, fundamental anchoring system design procedures are suggested to apply huge marine ranching complex with increase of the holding capacity of anchor under the optimum cost.

• Transactions on Electrical and Electronic Materials
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• 제8권6호
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• pp.246-249
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• 2007

A triple-band antenna was developed and fabricated by LDS(Laser Direct Structuring) process. The effects of the plating rate and heat treatment condition were investigated and the gains of fabricated antennas were measured at various frequencies. The laser irradiated surface shows clearly that there are prominence and depression. It shows anchoring effect between a plating material and ablation surface. The plating rate was decreased when the plating material is exhausted in the solution. This solution needs to refreshed by the new aid solution. The copper plating thickness is decreased with the increase of heat treatment temperature in the same time but it does not change other condition. The gain of LDS antenna showed higher than the generally processed antenna. This result was related with practical use of the dimension and effective dielectric constant.