• 한국전기전자재료학회논문지
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• 제15권9호
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• pp.776-782
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• 2002

The microstructure, V-Ι characteristics, and stability of ZnO-P $r_{6}$ $O_{11}$ CoO-C $r_2$ $O_3$- $Y_2$ $O_3$-based varistor ceramics were investigated with cooling rate in the range of 2~8$^{\circ}C$/min. The cooling rate relatively weakly affected the microstructure, the varistor voltage, and the leakage current in the V-Ι characteristics. But the nonlinear exponent relatively strongly affected by cooling rate. The cooling rate also greatly affected the stability of V-Ιand dielectric characteristics for DC accelerated aging stress. On the whole, the varistors cooled with 4$^{\circ}C$/fin exhibited the highest performance in the densification, nonlinearity, and stability. Especially, they exhibited a high stability, in which the variation rate of the varistor voltage( $V_{1㎃}$), the nonlinear exponent($\alpha$), and the dissipation factor(tan $\delta$) is -1.4%, -4.9%, and ＋60.0%, respectively, under DC accelerated aging stress such as 0.95 $V_{1㎃}$15$0^{\circ}C$/12 h)

• 한방안이비인후피부과학회지
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• 제36권1호
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• pp.40-49
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• 2023

Objectives : This study was conducted to confirm the skin anti-aging effect of Chungpyesagan-tang(CPSGT) extract. Methods : We performed MMT assay to confirm the cytotoxicity of CPSGT. After inducing matrix metalloproteinase-1(MMP-1) with tumor necrosis factor-α(TNF-α), we investigated mRNA expression and protein secretion of MMP-1 by real-time RT-PCR and ELISA. In addition, we measured the protein expression of mitogen-activated protein kinases(MAPKs) and transcription factors by western blot. Results : CPSGT was not cytotoxic at 25-800㎍/㎖. The mRNA expression and protein secretion of MMP-1 decreased when treated with CPSGT. The protein expression of p-ERK, p-JNK, p-p38 was decreased by CPSGT. In addition, the protein expression of p-c-jun and p-NF-κB, which are transcription factors, were also decreased. Conclusion : This suggests that CPSGT can inhibit MMP-1 and thus be a potential anti-aging substance.

• 기본간호학회지
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• 제7권2호
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• pp.271-286
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• 2000

This study is designed to investigate what elders think about the meaning of aging. We have used Q-methods to identify meaning of aging from elders, and developed self-referenced surveys to analyze characteristics In this study, we used a non-structured method to select Q sampling. From 183 Q populations, we selected 36 Q sampling. A total of 32 persons sixty-years or older were randomly selected for P samples, When the Q-sorting was complete, we interviewed the participants at both end of the extremes(agree or disagree), and documented their responses. We used PC QUANL to process the data and used principal component analysis for Q factor analysis. There were five subjective types for the meaning of aging by elders. Of the 32 P-samples of elders, 11 were identified as Type 1, 7 as Type 2, 2 as Type 3, 8 as Type 4, and 4 as Type 5. Type 1 : 'Matured elders' Elders wished the well being of their children, thought older persons should maintain good health, worried about becoming senile, and dependent God believing in life after death. Type 2 : 'Assertive-Rights' Elders categorized as Assertive-Rights insisted on their rights to life as a person. Type 2 elders characterized themselves as people who should keep themselves healthy, become weak and lack sexual desires, act selfish like a child, need to be protected, and be financially independent. Type 3 : 'Passive-Dependents' Elders characterize themselves as those who pray for their children's well being, worry about the children even after their death. and becoming senile. Type 4 : 'Hopeless' The 'Hopeless' type of elders characterized aging as a time to pray for their children, insignificant beings, thoughts were selfish and child-like, poor, worried about going senile, regret their life overall, and preferred to die than to live as an old person. Type 5 : 'Attached-Present' The 'Attached-Present' type of elders thought elderly characterized themselves as acting selfish and child-like, wiser, anxious, regret their life, stand aloof of greed and worldly things, being a model for the society, and deserving to be treated with filial respect. Thus far, Korean elders seemed to have a positive and negative meaning of aging due to the current changes in the society, value system, and family structures. The above five subjective meanings of aging confirm that we need to approach and nurse the elderly differently. Years of aging are a part of and a natural process of life with various physical, psychological, and sociological changes. Nurses need to assist elderly to find the positive meaning of their life by providing appropriate physical, psychological, and social support at an earlier stage in nursing. Based on this study, we could derive the following two implication from the perspectives of science of nursing to care for elders. 1) Based on the studies investigating the type of meaning of aging, we could develop tools to assist in nursing intervention programs for elderly. 2) Based on research on the meaning of aging for different developmental stages of life, we could develop a model for roles for different family members in nursing and caring for the elders.

• 한국융합학회논문지
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• 제8권5호
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• pp.255-263
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• 2017

이 연구는 한국 신노년층의 회복탄력성과 생산적 노화의 관계에서 자아존중감의 매개효과를 실증적으로 구명하는데 목적이 있다. 이에 따른 연구대상은 대도시와 중/소도시 그리고 농촌지역 신노년층을 모집단으로 설정하고, 집락무선표집방법을 통해 484명을 대상으로 자료를 수집하였다. 자료분석은 통계프로그램인 IBM SPSS 20.0과 AMOS 5.0 프로그램을 활용하여, 빈도분석, 탐색적 요인분석, 확인적 요인분석, 신뢰도 분석 그리고, 공변량구조 분석을 실시하였다. 이러한 과정을 통해 다음과 같은 결과을 얻었다. 첫째, 한국 신노년들의 회복탄력성은 자아존중감에 영향을 미친다. 둘째, 한국 신노년들의 회복탄력성은 생산적 노화에 영향을 미친다. 셋째, 한국 신노년들의 자아존중감은 생산적 노화에 영향을 미친다. 그리고 마지막으로 넷째, 한국 신노년들의 회복탄력성과 생산적 노화의 관계에서 자아존중감은 부분매개로서 매개효과가 있다.

• 한국의류산업학회지
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• 제14권3호
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• pp.423-429
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• 2012

This study investigated purchasing practice and size satisfaction to offer basic data to establish a marketing strategy and produce down-aging clothes for females in their 40s-50s. For the data analysis, crosstabs, factor analysis, and one-way ANOVA were used. The results were as follows; first, middle-aged women were observed to purchase down-aging clothes "to look younger" and not purchase clothes "due to the lack of right sizes." For women who answered to 'not purchase clothes', they also acknowledged that they intended to purchase down-aging clothes in the future if the right size is available. Second, people in their early 40s significantly considered perceptual qualities such as fashion and brand names while people in their late 50s placed the most importance in practicality and wearability. For body shapes, people with overweight body types were found to significantly consider physical performance, practicality, and wearability. Third, the examination of purchase satisfaction levels by age groups showed that younger age groups had high satisfaction level for wear functionality related items that included size and activity however, the late 50s group had the lowest satisfaction level. Middle-aged women purchased clothes to look younger however, they simultaneously wear clothes that are plain and conservative or respectable and graceful. Therefore, the development of products reflect the analysis of designs that can help create a more youthful appearance and women's preferred styles are needed in addition to the establishment of a differentiated sizing system for middle-aged female consumers in the incorporation of the characteristics of middle-aged women's body parts.

• 성인간호학회지
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• 제29권1호
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• pp.41-50
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• 2017

Purpose: The purpose of this study was to identify and compare the factors influencing attitude toward one's own aging among Korean middle-aged adults and the elderly. Methods: A cross sectional study was performed with a total sample of 70 middle-aged adults and 64 elderly reside in two metropolitan areas. Data were collected from August 2015 to November 2015 using the Perceived Health Status Scale, the Health Locus of Control Scale and the Attitude Toward own Aging (ATOA) Scale. The statistics used include percentage, t-test, Pearson's correlation coefficient, and multiple regression. Results: Mean age for each age group were about 52 and 76 years old for middle-aged adults and the elderly respectively. A considerable proportion of all participants reported a negative attitude toward aging. Perceived health status was the common factor influencing attitude toward one's own aging in both age groups. Middle-aged adults identified presence of chronic illness and internal health locus of control as important factors. In contrast, the elderly reported that education and others-dependent health locus of control such as powerful others had a significant impact on ATOA. Each regression model explained 31% and 55% of the total variance of ATOA among middle-aged adults and among the elderly. Conclusion: Both middle-aged adults and the elderly with low perceived health status are at risk of negative ATOA's. The type health locus of control need to be identified and utilized based on individuals' tendency to improve positive ATOA. That is, middle-aged adults might need reinforcement of their self-will whereas the elderly might need enhancement of social support and network of family and healthcare providers.

• 한국축산식품학회지
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• 제39권6호
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• pp.934-942
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• 2019

Previous studies on dry aged beef, which substantially increases the value of low-grade raw beef and non-preferred cuts, are currently limited to the observation of aged beef changes in laboratory settings or under particular aging conditions, whereas the factors influencing aging have so far been underexplored. Herein, we attempt to establish a technique for distinguishing between fresh and aged beef by observing changes in quality during beef aging. Specifically, we analyzed the effect of time on the quality of aged beef sourced from three Korean manufacturers and identified quality indicators that can be used to distinguish between fresh and aged beef, regardless of supplier. Storage/trimming/aging/cooking losses, moisture/fat/protein/collagen contents, and water holding capacity were tested as potential indicators, among other parameters. As a result, the quality of dry aged beef was shown to be supplier-dependent, which made the identification of factors for the above origin-independent discrimination difficult. Nevertheless, as storage loss, water holding capacity, and cooking loss significantly changed with dry aging time in all cases, these parameters were concluded to be potentially suited for discrimination purposes. The insights gained in this work may help promoting further research in this field and contribute to the development of a standard for consistent aged beef production.

• The Korean Journal of Physiology and Pharmacology
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• 제25권6호
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• pp.575-583
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• 2021

Composition of the gut microbiota changes with aging and plays an important role in age-associated disease such as metabolic syndrome, cancer, and neurodegeneration. The gut microbiota composition oscillates through the day, and the disruption of their diurnal rhythm results in gut dysbiosis leading to metabolic and immune dysfunctions. It is well documented that circadian rhythm changes with age in several biological functions such as sleep, body temperature, and hormone secretion. However, it is not defined whether the diurnal pattern of gut microbial composition is affected by aging. To evaluate aging effects on the diurnal pattern of the gut microbiome, we evaluated the taxa profiles of cecal contents obtained from young and aged mice of both sexes at daytime and nighttime points by 16S rRNA gene sequencing. At the phylum level, the ratio of Firmicutes to Bacteroidetes and the relative abundances of Verrucomicrobia and Cyanobacteria were increased in aged male mice at night compared with that of young male mice. Meanwhile, the relative abundances of Sutterellaceae, Alloprevotella, Lachnospiraceae UCG-001, and Parasutterella increased in aged female mice at night compared with that of young female mice. The Lachnospiraceae NK4A136 group relative abundance increased in aged mice of both sexes but at opposite time points. These results showed the changes in diurnal patterns of gut microbial composition with aging, which varied depending on the sex of the host. We suggest that disturbed diurnal patterns of the gut microbiome can be a factor for the underlying mechanism of age-associated gut dysbiosis.

• 동의생리병리학회지
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• 제28권5호
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• pp.530-536
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• 2014

Root barks of Paeonia suffruticosa Andrews (PS) was reported as contraindicated drugs of pregnancy by many Korean medical classics. Recently, a major ingredient component of PS, paeonol was reported that has contraceptive effect on early pregnancy in rats. However, the accurate molecular mechanism is not clear. In this study, we showed that PS decreased the expression of receptor for leukemia inhibitory factor (LIFR) in human endometrial Ishikawa cells at non-toxic dose, although the expression of leukemia inhibitory factor (LIF) was increased by PS. In addition, PS inhibited the adhesion of human trophoblastic JAR cells onto Ishikawa cells. Given importance of LIF-LIFR signaling pathway in the process of embryo implantation, the decreased LIFR expression by PS will be a good explanation on the PS- or its ingredient compounds-induced contraception.

• 디지털융복합연구
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• 제16권5호
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• pp.361-372
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• 2018

본 연구의 목적은 중년여성의 노화 도구를 개발하는 것으로 연구대상자는 대도시 중년여성 385명을 대상으로 수집하였고, 개발과정은 예비문항 개발, 내용 타당도와 신뢰성 검증, 최종 문항의 요인분석 및 신뢰도와 타탕도를 검증하였다. 요인분석 결과 본 도구는 9개의 요인으로 구성되었고, '자기성취감', '신체변화적응', '심리변화적응', '대인관계', '갱년기증상적응', '경제적 안정', '신체건강유지', '사회적 지지', '사회변화적응'으로 명명되었다. 본 연구에서 개발한 도구는 전체 설명변량이 64.03%로 충분하였으며, 전체 신뢰도도 Cronbach' ${\alpha}$값 .90으로 높았고, 우울과의 상관관계 분석에서는 부적 상관관계(r=-.69, p<.001)가 있는 것으로 나타나 동시타당도가 검증되었다. 본 도구는 높은 타당성과 신뢰도를 가지는 것으로 확인되어 중년여성의 성공적 노화를 측정하기 위한 도구로 유용할 것이다. 본 연구에서 개발한 도구는 반복 연구를 통해 추후 중년여성의 성공적 노화를 지지하기 위한 프로그램 개발의 기초자료를 마련하는데 기여할 것으로 사료된다.