• Title/Summary/Keyword: Aging factor

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Effect of Cooling Rate on DC Accelerated Aging Characteristics of ZPCCY-Based Varistor Ceramics (ZPCCY계 바리스터 세라믹스의 DC 가속열화 특성에 미치는 냉각속도의 영향)

  • 남춘우;김향숙
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.15 no.9
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    • pp.776-782
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    • 2002
  • The microstructure, V-Ι characteristics, and stability of ZnO-P $r_{6}$ $O_{11}$ CoO-C $r_2$ $O_3$- $Y_2$ $O_3$-based varistor ceramics were investigated with cooling rate in the range of 2~8$^{\circ}C$/min. The cooling rate relatively weakly affected the microstructure, the varistor voltage, and the leakage current in the V-Ι characteristics. But the nonlinear exponent relatively strongly affected by cooling rate. The cooling rate also greatly affected the stability of V-Ιand dielectric characteristics for DC accelerated aging stress. On the whole, the varistors cooled with 4$^{\circ}C$/fin exhibited the highest performance in the densification, nonlinearity, and stability. Especially, they exhibited a high stability, in which the variation rate of the varistor voltage( $V_{1㎃}$), the nonlinear exponent($\alpha$), and the dissipation factor(tan $\delta$) is -1.4%, -4.9%, and +60.0%, respectively, under DC accelerated aging stress such as 0.95 $V_{1㎃}$15$0^{\circ}C$/12 h)

Studies on Skin Anti-aging Effect of Chungpyesagan-tang(CPSGT) (청폐사간탕(淸肺瀉肝湯)의 피부 항노화 효과에 대한 연구)

  • Bo-Hee, Jeon;Young-Chae, Song;Hee-Taek, Kim;Yong-Min, Kim
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.36 no.1
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    • pp.40-49
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    • 2023
  • Objectives : This study was conducted to confirm the skin anti-aging effect of Chungpyesagan-tang(CPSGT) extract. Methods : We performed MMT assay to confirm the cytotoxicity of CPSGT. After inducing matrix metalloproteinase-1(MMP-1) with tumor necrosis factor-α(TNF-α), we investigated mRNA expression and protein secretion of MMP-1 by real-time RT-PCR and ELISA. In addition, we measured the protein expression of mitogen-activated protein kinases(MAPKs) and transcription factors by western blot. Results : CPSGT was not cytotoxic at 25-800㎍/㎖. The mRNA expression and protein secretion of MMP-1 decreased when treated with CPSGT. The protein expression of p-ERK, p-JNK, p-p38 was decreased by CPSGT. In addition, the protein expression of p-c-jun and p-NF-κB, which are transcription factors, were also decreased. Conclusion : This suggests that CPSGT can inhibit MMP-1 and thus be a potential anti-aging substance.

A Subjectivity Study on the Meaning of Aging for Elders (노인의 의미에 대한 주관성 연구)

  • Lee Keum-Jae;Park In-Sook;Kim Boon-Han
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.7 no.2
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    • pp.271-286
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    • 2000
  • This study is designed to investigate what elders think about the meaning of aging. We have used Q-methods to identify meaning of aging from elders, and developed self-referenced surveys to analyze characteristics In this study, we used a non-structured method to select Q sampling. From 183 Q populations, we selected 36 Q sampling. A total of 32 persons sixty-years or older were randomly selected for P samples, When the Q-sorting was complete, we interviewed the participants at both end of the extremes(agree or disagree), and documented their responses. We used PC QUANL to process the data and used principal component analysis for Q factor analysis. There were five subjective types for the meaning of aging by elders. Of the 32 P-samples of elders, 11 were identified as Type 1, 7 as Type 2, 2 as Type 3, 8 as Type 4, and 4 as Type 5. Type 1 : 'Matured elders' Elders wished the well being of their children, thought older persons should maintain good health, worried about becoming senile, and dependent God believing in life after death. Type 2 : 'Assertive-Rights' Elders categorized as Assertive-Rights insisted on their rights to life as a person. Type 2 elders characterized themselves as people who should keep themselves healthy, become weak and lack sexual desires, act selfish like a child, need to be protected, and be financially independent. Type 3 : 'Passive-Dependents' Elders characterize themselves as those who pray for their children's well being, worry about the children even after their death. and becoming senile. Type 4 : 'Hopeless' The 'Hopeless' type of elders characterized aging as a time to pray for their children, insignificant beings, thoughts were selfish and child-like, poor, worried about going senile, regret their life overall, and preferred to die than to live as an old person. Type 5 : 'Attached-Present' The 'Attached-Present' type of elders thought elderly characterized themselves as acting selfish and child-like, wiser, anxious, regret their life, stand aloof of greed and worldly things, being a model for the society, and deserving to be treated with filial respect. Thus far, Korean elders seemed to have a positive and negative meaning of aging due to the current changes in the society, value system, and family structures. The above five subjective meanings of aging confirm that we need to approach and nurse the elderly differently. Years of aging are a part of and a natural process of life with various physical, psychological, and sociological changes. Nurses need to assist elderly to find the positive meaning of their life by providing appropriate physical, psychological, and social support at an earlier stage in nursing. Based on this study, we could derive the following two implication from the perspectives of science of nursing to care for elders. 1) Based on the studies investigating the type of meaning of aging, we could develop tools to assist in nursing intervention programs for elderly. 2) Based on research on the meaning of aging for different developmental stages of life, we could develop a model for roles for different family members in nursing and caring for the elders.

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The Meditation Effects of Self-esteem on the Relationship model between Korean new elderly class's Recovery resilience and Productive aging (한국 신노년층의 회복탄력성과 생산적 노화의 관계에서 자아존중감의 매개효과 검증)

  • Yi, Eun-Surk;An, Chan-Woo;Cho, Gun-Sang
    • Journal of the Korea Convergence Society
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    • v.8 no.5
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    • pp.255-263
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    • 2017
  • The purpose of this study was to investigate the meditation effects of self-esteem on the relationship model between Korean new elderly class's recovery resilience and productive aging. This study sampled preliminary elderly people in other provinces nationwide. Data from a total of effective 484 subjects was analyzed. The collected data was processed using the IBM SPSS 20.0 and AMOS 5.0, and underwent descriptive statistical analysis, confirmatory factor analysis, and structure model verification. The results are as follows; First, recovery resilience of Korean new elderly class's affect their self-esteem. Second, recovery resilience of Korean new elderly class's affect their productive aging. Third, self-esteem of Korean new elderly class's affect their productive aging. Lastly thel relationship among recovery resilience, self-esteem and productive aging of Korean new elderly class's shows partial mediation, and there is the mediation effect.

A Study on the Purchasing Practice and Satisfaction of Down-aging Clothes for the Female in their 40s-50s (4050세대 여성의 다운-에이징(Down-aging) 의류 구매실태 및 치수만족도 조사)

  • Lim, Ji-Young
    • Fashion & Textile Research Journal
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    • v.14 no.3
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    • pp.423-429
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    • 2012
  • This study investigated purchasing practice and size satisfaction to offer basic data to establish a marketing strategy and produce down-aging clothes for females in their 40s-50s. For the data analysis, crosstabs, factor analysis, and one-way ANOVA were used. The results were as follows; first, middle-aged women were observed to purchase down-aging clothes "to look younger" and not purchase clothes "due to the lack of right sizes." For women who answered to 'not purchase clothes', they also acknowledged that they intended to purchase down-aging clothes in the future if the right size is available. Second, people in their early 40s significantly considered perceptual qualities such as fashion and brand names while people in their late 50s placed the most importance in practicality and wearability. For body shapes, people with overweight body types were found to significantly consider physical performance, practicality, and wearability. Third, the examination of purchase satisfaction levels by age groups showed that younger age groups had high satisfaction level for wear functionality related items that included size and activity however, the late 50s group had the lowest satisfaction level. Middle-aged women purchased clothes to look younger however, they simultaneously wear clothes that are plain and conservative or respectable and graceful. Therefore, the development of products reflect the analysis of designs that can help create a more youthful appearance and women's preferred styles are needed in addition to the establishment of a differentiated sizing system for middle-aged female consumers in the incorporation of the characteristics of middle-aged women's body parts.

Attitude toward One's Own Aging among Korean Middle-aged Adults and the Elderly (중장년 성인과 노인의 노화에 대한 태도)

  • Jo, Ahra;Oh, Heeyoung
    • Korean Journal of Adult Nursing
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    • v.29 no.1
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    • pp.41-50
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    • 2017
  • Purpose: The purpose of this study was to identify and compare the factors influencing attitude toward one's own aging among Korean middle-aged adults and the elderly. Methods: A cross sectional study was performed with a total sample of 70 middle-aged adults and 64 elderly reside in two metropolitan areas. Data were collected from August 2015 to November 2015 using the Perceived Health Status Scale, the Health Locus of Control Scale and the Attitude Toward own Aging (ATOA) Scale. The statistics used include percentage, t-test, Pearson's correlation coefficient, and multiple regression. Results: Mean age for each age group were about 52 and 76 years old for middle-aged adults and the elderly respectively. A considerable proportion of all participants reported a negative attitude toward aging. Perceived health status was the common factor influencing attitude toward one's own aging in both age groups. Middle-aged adults identified presence of chronic illness and internal health locus of control as important factors. In contrast, the elderly reported that education and others-dependent health locus of control such as powerful others had a significant impact on ATOA. Each regression model explained 31% and 55% of the total variance of ATOA among middle-aged adults and among the elderly. Conclusion: Both middle-aged adults and the elderly with low perceived health status are at risk of negative ATOA's. The type health locus of control need to be identified and utilized based on individuals' tendency to improve positive ATOA. That is, middle-aged adults might need reinforcement of their self-will whereas the elderly might need enhancement of social support and network of family and healthcare providers.

Determination of Indicators for Dry Aged Beef Quality

  • Lee, Heeyoung;Jang, Mi;Park, Sunhyun;Jeong, Jiyoun;Shim, You-Shin;Kim, Jong-Chan
    • Food Science of Animal Resources
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    • v.39 no.6
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    • pp.934-942
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    • 2019
  • Previous studies on dry aged beef, which substantially increases the value of low-grade raw beef and non-preferred cuts, are currently limited to the observation of aged beef changes in laboratory settings or under particular aging conditions, whereas the factors influencing aging have so far been underexplored. Herein, we attempt to establish a technique for distinguishing between fresh and aged beef by observing changes in quality during beef aging. Specifically, we analyzed the effect of time on the quality of aged beef sourced from three Korean manufacturers and identified quality indicators that can be used to distinguish between fresh and aged beef, regardless of supplier. Storage/trimming/aging/cooking losses, moisture/fat/protein/collagen contents, and water holding capacity were tested as potential indicators, among other parameters. As a result, the quality of dry aged beef was shown to be supplier-dependent, which made the identification of factors for the above origin-independent discrimination difficult. Nevertheless, as storage loss, water holding capacity, and cooking loss significantly changed with dry aging time in all cases, these parameters were concluded to be potentially suited for discrimination purposes. The insights gained in this work may help promoting further research in this field and contribute to the development of a standard for consistent aged beef production.

Aging effects on the diurnal patterns of gut microbial composition in male and female mice

  • Kim, Hyun-Jung;Moon, Chang Mo;Kang, Jihee Lee;Park, Eun-Mi
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.6
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    • pp.575-583
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    • 2021
  • Composition of the gut microbiota changes with aging and plays an important role in age-associated disease such as metabolic syndrome, cancer, and neurodegeneration. The gut microbiota composition oscillates through the day, and the disruption of their diurnal rhythm results in gut dysbiosis leading to metabolic and immune dysfunctions. It is well documented that circadian rhythm changes with age in several biological functions such as sleep, body temperature, and hormone secretion. However, it is not defined whether the diurnal pattern of gut microbial composition is affected by aging. To evaluate aging effects on the diurnal pattern of the gut microbiome, we evaluated the taxa profiles of cecal contents obtained from young and aged mice of both sexes at daytime and nighttime points by 16S rRNA gene sequencing. At the phylum level, the ratio of Firmicutes to Bacteroidetes and the relative abundances of Verrucomicrobia and Cyanobacteria were increased in aged male mice at night compared with that of young male mice. Meanwhile, the relative abundances of Sutterellaceae, Alloprevotella, Lachnospiraceae UCG-001, and Parasutterella increased in aged female mice at night compared with that of young female mice. The Lachnospiraceae NK4A136 group relative abundance increased in aged mice of both sexes but at opposite time points. These results showed the changes in diurnal patterns of gut microbial composition with aging, which varied depending on the sex of the host. We suggest that disturbed diurnal patterns of the gut microbiome can be a factor for the underlying mechanism of age-associated gut dysbiosis.

Mechanism Study on Inhibition of Pregnancy by Root Barks of Paeonia suffruticosa (목단피에 의한 임신 저해의 분자적 기전에 대한 연구)

  • Choi, Hee Jung;Kim, Eun Young;Choi, Hee Jin;Park, Mi Ju;Chung, Tae Wook;Park, Seong Ha;Kim, So Yeon;Ha, Ki Tae
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.5
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    • pp.530-536
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    • 2014
  • Root barks of Paeonia suffruticosa Andrews (PS) was reported as contraindicated drugs of pregnancy by many Korean medical classics. Recently, a major ingredient component of PS, paeonol was reported that has contraceptive effect on early pregnancy in rats. However, the accurate molecular mechanism is not clear. In this study, we showed that PS decreased the expression of receptor for leukemia inhibitory factor (LIFR) in human endometrial Ishikawa cells at non-toxic dose, although the expression of leukemia inhibitory factor (LIF) was increased by PS. In addition, PS inhibited the adhesion of human trophoblastic JAR cells onto Ishikawa cells. Given importance of LIF-LIFR signaling pathway in the process of embryo implantation, the decreased LIFR expression by PS will be a good explanation on the PS- or its ingredient compounds-induced contraception.

The Development of Healthy Aging Scale for Middle aged Women: Convergent Approach (중년여성의 성공적 노화 측정 도구 개발: 융복합적 접근)

  • Jung, Hye-Yun;Sung, Kyung Mi
    • Journal of Digital Convergence
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    • v.16 no.5
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    • pp.361-372
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    • 2018
  • The purpose of this study was to develop an assessment scale for healthy aging of middle aged women. The data were collected from 385 middle aged women in two large cities in Korea. The development processes of the scale were followed: Development of preliminary items; Verification of content validity and reliability; Factor analysis and criterion validity of final items. Results: Factor analysis resulted in the creation of the final scale, which consisted of 38 items that were grouped into 9 factors: self achievement, physical change adaptation, psychological change adaptation, interpersonal relationships, menopausal symptom adaptation, economic stability, physical health, social support, social change adaptation. The explanatory variance was 64.03%. The reliability of the scale was Cronbach's ${\alpha}=.90$. Correlation of the scale with healthy aging and depression, established its construct and concurrent validity was r=-.69, p<.001. The scale was confirmed to have a relatively high validity and reliability. The findings of the study can be useful as a measurement to evaluate healthy aging of middle aged women. Future researches with the scale will be helpful for basic data for the program development to support healthy aging of middle aged women.