• 동의생리병리학회지
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• 제34권6호
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• pp.279-284
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• 2020

The theory of "eccentric diseases are generally due to phlegm (怪病多屬痰)" means that phlegm is a major cause for intractable diseases including cerebrovascular accident, depression, insanity, and shock from strange things or evil sprint. It has been a key foundation for the diagnosis and treatment of phlegm in traditional Korean medicine. However, the origin of the theory is not clear and controversial. In this study, we critically reviewed the origin and developing process of the theory in the viewpoints of philology and pathology in Korean medicine. Wang Yin-Jun (王隱 君) did not claim that eccentric diseases are generally due to phlegm in Taidingyangshengzhu-lun (泰定養生主論). The miscitation by following medical literature caused the misunderstanding in the meaning of Taidingyangshengzhu-lun, that phlegm can cause variable symptoms and signs. In the Ming dynasty, some poor medical doctors had tended to diagnose any difficult case as phlegm syndrome and to use Kuntan-huan (滾痰丸) as a standard herbal formula for treating phlegm syndrome. However, the tendency to categorize delicate cases easily to phlegm syndrome is not desirable. Besides, the tendency to use Kuntan-huan as a basic formula for the phlegm syndrome might cause diverse and severe adverse effects. Thus, we cannot accept the theory of eccentric diseases is generally due to phlegm without a doubt. In conclusion, this theory might be a valuable aphorism in terms of considering the possibility of the secondary pathologic factors including phlegm and blood stasis which should be considered first in case of intractable diseases.

• 한국응용과학기술학회지
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• 제40권1호
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• pp.88-94
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• 2023

세리신은 누에고치에서 추출한 단백질로 많은 건강상의 이점을 가지고 있다. 본 연구는 화장품 소재로서 누에고치에서 유래된 세리신 표준품의 항주름 활성 및 항염증 활성을 평가하기 위해 수행되었다. 세리신의 항산화 효과는 DPPH 및 ABTS 측정법에 의해 측정되었다. 또한 대식세포인 Raw 264.7 cell에서의 세포 생존율을 확인하였으며, lipoplyscaccharide를 이용하여 유도된 염증반응을 이용하여 세리신의 항염증 효과를 조사하였다. 그 결과 세리신은 DPPH, ABTS에서 항산화 활성을 보였으며 세포 독성을 가지지 않은 1,000 ㎍/mL의 농도에서 NO를 억제하였다. 종합하여 세리신은 항산화 활성을 가지며 항노화 및 항염증 화장품의 우수한 소재가 될 수 있음을 보여준다.

• 한국농촌건축학회논문집
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• 제26권2호
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• pp.47-56
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• 2024

Through an examination of future societal development, it was found that the demographic structure is gradually aging, thus placing higher demands on elderly welfare centers. This study conducted surveys on three elderly day care centers in the entire region, aiming to enhance the pivotal role of elderly day care centers in the welfare facilities for the elderly. The current usage status, interior architectu/ral evaluations, and questionnaire surveys of these centers were analysed. The results of investigation into the architectural environment of the elderly day care centers showed that in terms of physical environment, smaller-scale centers did not lag behind larger ones in internal facilities, but larger-scale centers excelled in spatial utilization. Furthermore, the results of questionnaire survey results revealed correlations between family relationships, health status, level of assistance required, and satisfaction with facility usage, while no correlation was found between usage time, health status, and satisfaction with facility usage. This study conducted basic investigations such as architectural and physical surveys, and questionnaire surveys on elderly day care centers. Based on the survey results, future design practices should continuously explore and innovate to meet the needs of an aging society, further improve the community care system, provide more comprehensive and meticulous services for the elderly, and lay the foundation for enhancing the quality of life for the elderly and providing comfortable services.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2008년도 추계 학술논문 발표대회
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• pp.37-41
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• 2008

According to the recent rapidly increasing that construction works are gradually Manhattanized mainly the grand scaled residential buildings, the foundation of the building that is related to safety is increasing for building as a grand scaled mat concrete. Because mat concrete can not be simultaneously placing of concrete in a great quantity due to the circumstance at the field, the inequal deformation of the tensile stress that according to the time lag of hydration heat between the upper layer and the lower layer is affecting as a cause that is the possibility of crack occurrence by increasing. Accordingly, this research checked the efficiency of super retard concrete in applying real structures, and we implemented the preparatory experiment to settle up the inequal deformation of the tensile stress substantially that is according to the time lag of placement between the upper layer and the lower layer by controlling the setting time using the super retarding agent. As the result of test, the more target of delay time lengthened, the more fluidity increased and air content indicated a little differences. There was from 2 to 10 hours between the standard curing and the outside curing at the setting time and in case of calculating the rate of mixing at real structure is required that mix promotion, increasing the amount of mixing, by setting up the curing temperature. The super retard concrete showed the result that in compressive strength, early-age strength was smaller than normal concrete whereas it was same or more figures from at the aging 28days because of the super retarding agent.

• 한국학교수학회논문집
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• 제10권2호
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• pp.173-185
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• 2007

매우 빠른 속도로 진행되고 있는 현재의 고령화 사회에 맞추어, 평생 교육의 중요성은 나날이 증대되고 있다. 온전한 삶을 살아가는 가치가 확산됨으로써 치매예방이나 건강한 두뇌를 위해서 뇌 활동이 강조되고 있다. 본고는 이를 위한 새로운 방안으로 노인교육의 일환으로 수학이라는 학문을 도입하여 노인의 정서적 인지적 수준에 적합한 수업내용을 고안하여 적용하는 수학교육 실천을 제안하고 있다. 노인의 기억력 증진과 사고력과 논리력을 신장시킬 수 있고, 게임 활동을 통하여 흥미를 유발시킬 수 있으며 궁극적으로는 자아개념과 자긍심을 높일 수 있는 '실버수학'을 제안하고, 이러한 '실버수학'의 구체적인 연구가 진행될 수 있도록 그 기본 요구 사항들을 제안하였다.

• 복식문화연구
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• 제24권2호
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• pp.150-165
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• 2016

With signs of the redevelopment of the domestic sewing industry, national support agencies were established. This study aims to assess the present conditions of the domestic sewing industry and investigate the effectiveness of national sewing industry support policies. According to the results of a survey of 30 sewing companies managers, the biggest factor causing product defects was work being rushed because of tight delivery dates, and the reduction in sales was caused by a lack of orders. Moreover, sewing technicians are aging, and the biggest reason for their decrease in number is that people do not pursue the job because of the common understanding that it is difficult. Managers perceived that the government's sewing technician training program was not a practical help. They were well aware of the support program to improve the work environment and the sewing equipment support program and showed high satisfaction with these programs, but they complained that the period for equipment rental was fixed. A majority of them thought that the Korean sewing industry environment had still not improved, and were skeptical about its future outlook. They identified its most urgent needs as the expansion of orders and the securing of manpower. The support programs that they wanted urgently included support for employees' four major public insurances and the enactment of the increase of toll processing fees.

• Journal of Genetic Medicine
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• 제20권2호
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• pp.39-45
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• 2023

As advanced sequencing technologies continue to uncover an increasing number of variants in genes associated with human genetic diseases, there is a growing demand for systematic approaches to assess the impact of these variants on human development, health, and disease. While in silico analyses have provided valuable insights, it is essential to complement these findings with model organism studies to determine the functional consequences of genetic variants in vivo. Drosophila melanogaster is an excellent genetic model for such functional studies due to its efficient genetic technologies, high gene conservation with humans, accessibility to mutant fly resources, short life cycles, and cost-effectiveness. The traditional GAL4-UAS system, allowing precise control of gene expression through binary regulation, is frequently employed to assess the effects of monoallelic variants. Recombinase medicated cassette exchange or CRISPR-Cas9-mediated GAL4 insertion within coding introns or substitution of gene body with Kozak-Gal4 result in the loss-of-function of the target gene. This GAL4 insertion strategy also enables the expression of reference complementary DNA (cDNA) or cDNA carrying genetic variants under the control of endogenous regulatory cis elements. Furthermore, the CRISPR-Cas9-directed tissue-specific knockout and cDNA rescue system provides the flexibility to investigate candidate variants in a tissue-specific and/or developmental-timing dependent manner. In this review, we will delve into the diverse genetic techniques available in Drosophila and their applications in diagnosing and studying numerous undiagnosed diseases over the past decade.

• 산경연구논집
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• 제11권5호
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• pp.35-44
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• 2020

Purpose: The purpose of this study is to present a plan to expand the employment of the elderly in Small business as one of the ways to solve the problem of the supply and demand of the company due to the aging population and the problem of the elderly poverty. Research design, data and methodology: The method of this study is a qualitative research method, and the researcher visited a small and medium-sized company directly and collected data by conducting an in-depth interview with a business owner. The interview period was conducted on a total of 15 business owners from November 5, 2013 to November 18, 2013. Results: First, the reason why companies hire the elderly is because they are suitable people, and the reason why they are not employed is because the elderly are not suitable. Second, it was found that the most recruiting paths continued to work after retirement. Third, the strengths of the elderly in their businesses were diligence, integrity, leadership, wisdom, warmth, and skill. Disadvantages the elderly in their businesses include wanting to be treated as an adult, poor productivity, poor accuracy, and health risks. Fourth, in case of hiring the elderly, they were considering convergence with young employees, and it was suggested that there are no difficulties in being an elderly because the companies hiring the elderly use the elderly according to the characteristics of the elderly. Fifth, It is realistic to actively utilize the employment system after retirement. Sixth, it was found that, unlike young people, it is not easy to recruit people on the Internet, so it is necessary to improve the system. Lastly, some industries clearly distinguished between the jobs of the elderly and the jobs of the young, but in many industries, it was desirable to create jobs for the elderly by harmonizing the main and secondary jobs. Conclusion: Ultimately, the work of the elderly in small and medium-sized enterprises should be reborn as a high-quality job that can solve the poverty of the elderly by working as a regular worker in the enterprise, rather than simply working for the elderly.

• Steel and Composite Structures
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• 제17권4호
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• pp.405-429
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• 2014

In this paper, it is aimed to determine the structural behavior of suspension bridges considering construction stages and different soil conditions. Bosporus Suspension Bridge connecting the Europe and Asia in Istanbul is selected as an example. Finite element model of the bridge is constituted using SAP2000 program considering existing drawings. Geometric nonlinearities are taken into consideration in the analysis using P-Delta large displacement criterion. The time dependent material strength of steel and concrete and geometric variations is included in the analysis. Time dependent material properties are considered as compressive strength, aging, shrinkage and creep for concrete, and relaxation for steel. To emphases the soil condition effect on the structural behavior of suspension bridges, each of hard, medium and soft soils are considered in the analysis. The structural behavior of the bridge at different construction stages and different soil conditions has been examined. Two different finite element analyses with and without construction stages are carried out and results are compared with each other. At the end of the analyses, variation of the displacement and internal forces such as bending moment, axial forces and shear forces for bridge deck and towers are given in detail. Also, displacement and stresses for bridge foundation are given with detail. It can be seen from the analyses that there are some differences between both analyses (with and without construction stages) and the results obtained from the construction stages are bigger. It can be stated that the analysis without construction stages cannot give the reliable solutions. In addition, soil condition have effect on the structural behavior of the bridge. So, it is thought that construction stage analysis using time dependent material properties, geometric nonlinearity and soil conditions effects should be considered in order to obtain more realistic structural behavior of suspension bridges.

• 지역사회간호학회지
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• 제9권1호
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• pp.64-71
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• 1998

This study uses [the instrument of ageing anxiety] in order to find if a negative prejudice against the old affects the attitude toward sex of the aged. The result shows no significant relation between ageing anxiety and the knowledge of and attitude toward sex of the aged. However, it does show that the higher the ageing anxiety is, the lower the knowledge of sex and the more restrictive the attitude toward it. The knowledge of and attitude toward sex of the aged shows meaninggul changes after education. Nursing students who were educated come to have more knowledge about and are more open to it. This result supports the preposition of this study. As society grows older the endeavour to guarantee a high-quality life for the old is necessary and the old should be regarded as an entity which has its own characteristic desires. Especially for the old to enjoy a good life as a sexual being, the mystical barriers about sex and old age ought to be removed. In the future the old themselves may maintain sexual desires regardless of age and society will be required to correct its prejudice against the old having sex. Particularly nursing students, as an effort to provide the old with overall care, should examine the elderly's sexual desires in a physical, psychological, and social context and consider the normal sexual changes occuring during the aging process and finally integrate this information into their nursing plans. In order to fulfill this role successfully they should overcome their own prejudice and educate themselves about this particular problem. As the proportion of the old becomes bigger and the concern about the quality of their life grows, sex among the old will become more important in the nursing field. By putting an educational mediation programme into operation with nursing students and estimating the effect, this study supplies the foundation to activate new educational programmes. In short it tells us that education can be a practical method to confront the myth and conventions concerning sex among the aged.