• 한국IT서비스학회지
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• 제14권1호
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• pp.53-68
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• 2015

This article aims to identify the quality factors of public data which have increased as a public issue; analyze the impact of users satisfaction in the perspective of Technology Acceptance Model (TAM), and investigate the effect of service satisfaction on the government's open policy of public data. This study is consistent with Total Data Quality Management (TDQM) of MIT, it focuses on three main qualities except Contextual Data Quality (CDQ) and includes seven independent variables : accuracy, reliability, fairness for Intrinsic Data Quality (IDQ), accessibility, security for Accessibility Data Quality (ADQ), Consistent representation and understandability for Representational Data Quality (RDQ). Basing on TAM, the research model was conducted to examine which factors affect to perceived usefulness, perceived ease of use, service satisfaction and how service satisfaction affects to the government's open policy of public data. The results showed that accuracy, fairness, understandability affect both perceived ease of use and perceived usefulness; while reliability, consistent representation, security, and accessibility affect only perceived ease of use. This article found that the influence of perceived ease of use on perceived usefulness and the influence of these two causes on service satisfaction in the perspective of TAM were significant and it was consistent with prior studies. The service satisfaction when using public data leads to the reliability of public data open policy. As an initial study on unstructured public data open policy, this article offered quality factors that pubic data providers should consider and also present the operation plan of public data open policy in the future.

• 대기
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• 제17권4호
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• pp.471-481
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• 2007

전국 (60개 지점 평균)과 서울의 온도 및 강수를 분석하였다. 분석된 기간은 전국의 경우 1973-2007 년 기간 중 8월과 여름 및 서울의 경우 1908-2007년 기간 중 8월과 여름 이다. 금년 8월과 여름은 전국과 서울 모두 기온 (평균, 최고, 최저)이 평년에 비해 높았다. 전국의 경우 1973년부터 서울의 경우 1908년부터 8월과 여름 모두 최저기온이 꾸준히 증가하는 경향을 보인다. 최저 기온의 상승률은 평균 및 최고기온에 비하여 높다. 이러한 최저기온의 상승은 현재 전 지구적인 추세이며 전지구 온난화에 따른 증발량의 증가로 구름의 양이 증가하게 되어 최저기온이 상승한 것으로 해석하고 있다. 열대야라 불리는 최저기온 $25^{\circ}C$ 이상인 날은 8월과 여름 모두 1973년부터 2007년 현재까지 꾸준히 증가한다. 이는 전 지구 온난화와 도시화의 효과가 복합적으로 작용한 결과이다. 금년 8월의 전국 강수량 (60개 지점 평균)은 330.9mm 로 평년 (265.0 mm)보다 65.9 mm 많았다. 하지만 서울의 금년 8월 강수량은 237.6 mm 로 평년 (348.0mm)에 비해 110.4 mm 적었다. 전국의 금년 여름 강수량은 676.3 mm로 평년 (699.9 mm)과 비슷하였으며 서울은 566.2 mm 로 평년 (809.2 mm)모다 243.0 mm 적었다. 1973년부터 2007년까지 8월과 여름의 강수량을 분석한 결과 비록 변동 폭은 크나 1973년부터 (서울의 경우 1908년부터) 8월과 여름 모두 강수량은 증가하는 경향을 보인다. 전국 60개 지점의 8월 및 여름의 호우 일수 (120 mm 이상/일, 80 mm이상/일, 1시간 최다 30 mm 이상, 10분간 최다 10 mm 이상)는 1973년부터 꾸준히 증가하는 경향을 보였으나 금년에는 예외적으로 집중호우 현상이 일반적으로 오히려 감소한 것으로 분석되었다.

• 한국보건행정학회:학술대회논문집
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• 한국보건행정학회 2004년도 후기학술대회
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• pp.169-198
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• 2004

• 한국화재소방학회논문지
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• 제34권2호
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• pp.120-130
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• 2020

본 연구는 우리나라 소방조직에서 수행되는 예방소방행정과 대비소방행정이 대응소방행정에 미치는 영향을 실증적으로 분석하고자 수행되었다. 이를 위하여 2008년부터 2018년까지 16개 광역자치단체에서 수행된 예방소방행정과 대비소방행정, 그리고 대응소방행정에 대한 패널자료를 이용하여 통계분석을 실시하였다. 독립변인으로 예방소방행정과 대비소방행정을 사용했으며, 종속변인으로 대응소방행정을 사용하였다. 예비소방행정의 하위 변인으로 특정소방대상물 현황분석, 다중이용업 현황분석, 다중이용업 안전시설 완비 증명 발급, 소방특별조사을, 대비소방행정의 하위 변인으로 소방교육을, 대응소방행정의 하위 변인으로 화재진압출동을 사용하였다. 분석결과, 특정소방대상물 현황분석과 소방교육은 화재진압출동에 유의미한 양(+)의 영향을 미치는 것으로 나타났다. 본 연구결과는 소방행정의 효과성을 분석하는 연구에 기초자료로 사용될 수 있다.

• Toxicological Research
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• 제14권3호
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• pp.315-320
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• 1998

In vitro skin iritation of anti-inflammatory drugs was investigated in terms of the cytotoxicity method to human skin fibroblast cells. Five anti-inflammatory drugs (Diclofenac, Naproxen, Meclofenamic acid, Ibuprofen and Fnoprofen) which are commercially available as oral preparations or injections were tested. The cytotoxicity of 5 chemicals was evaluated by using MTT[tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay. NRU (neutral red uptake) assay and Alamar Blue assay after fibroblast cells had been exposed to the chemicals for 24 hours or 489 hours. The $IC_{50}$ values of the chemicals showed the comparative strength of cytotoxicity as following order of Meclofenamic acid>Diclofenac>Fenoprofen>Ibuprofen>Naproxen. The values of $IC_{50}$ determined by Alamar Blue assay were lower than those of MTT and NRU assay. These data suggest Alamar Blue assay can be useful method for assessing in vitro skin irritation potential of anti-inflammatory drugs.

• 한국잡초학회지
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• 제30권4호
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• pp.405-411
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• 2010

휴경논에 분포하고 있는 식생구조에 대해 식물사회학적 연구를 수행하였다. 총 22개 조사구에 대한 식생자료의 분석은 Zurich-Montpellier 학파의 방법을 이용하였다. 휴경논 식생조사 결과 1아군집, 5군락으로 구분되었다. 고마리군집(Polygonetum thunbergii Lohm. et Miyawaki 1962)의 고마리전형아군집, 골풀군락, 갈대군락, 물달개비군락, 사마귀풀군락, 부들군락. 요인분석에서 식생단위와 환경과의 상관관계를 보면, 사마귀풀군락과 물달개비군락은 토양 전질소와 음의 상관관계, 갈대군락과 고마리아군집은 토양 pH가 낮은 지역에 분포하는 것으로 분석되었다.

• Food Science and Biotechnology
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• 제16권6호
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• pp.868-872
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• 2007

The microbiological and chemical identification of antibiotic residues was attempted for livestock and seafood products including pork (n=34), beef (n=34), chicken (n=32), flatfish (n=37), armorclad rockfish (n=36), and sea bream (n=27). The meat (n=100) and seafood (n=100) samples were collected from 9 markets in 5 major Korean cities. Antibiotic substances were identified from the classes of tetracyclines, macrolides, penicillins, aminoglycosides, polyethers, peptides, sulfonamides, quinolones, chlorampenicols, and novobiocins using a microbiological assay, the Charm II test and high performance liquid chromatography (HPLC) with ultra violet (UV) and fluorescence detectors. The results showed that 2 tetracyclines (oxytetracycline and tetracycline) and 3 quinolones (ciprofloxacin, norfloxacin, and enrofloxacin) were detected in 4 samples of flatfish among all 100 seafood samples tested. No antibiotic residues were detected in the 100 livestock product samples tested. The amounts (min-max, mg/kg) of the residual antibiotics were as follows; tetracycline 0.78-0.85, oxytetracycline 0.49-0.74, ciprofloxacin 0.09-0.83, norfloxacin 0.01-0.21, enrofloxacin 0.12-2.98. These data indicate that the total detection rate of antibiotics in livestock and seafood products was approximately 2%.

• Archives of Pharmacal Research
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• 제22권5호
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• pp.474-478
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• 1999

Modulation of unscheduled DNA synthesis by dehydroepiandrosterone (DHEA) after exposure to various chemical carcinogens was investigated in the primary rat hepatocytes. Unscheduled DNA synthesis was induced by treatment of such direct acting carcinogens as methly methanesulfonate (MMS) and ethyl methanesulfonate (EMS) or procarcinogens including benzo(a)pyrene (BaP) and 7, 12-dimethylbenz(a)anthracene (DMBA). Unscheduled DNA synthesis was determined by measuring [methyl-3H]thymidine radioactivity incorporated into nuclear DNA of hepatocytes treated with carcinogens in the presence or absence of DHEA. Hydroxyurea $(5{\times}10^{-3} M)$was added to growth medium to selectively suppress normal replication. DHEA at concentrations ranging from $(1{\times}10^{-6} M)$ to$(5{\times}10^{-4} M)$ did not significantly inhibit unscheduled DNA synthesis induced by either MMS $(1{\times}10^{-4} M)$ or EMS $(1{\times}10^{-2} M)$. In contrast, DHEA-significantly inhibited unscheduled DNA synthesis induced by BaP $(6.5{\times}10^{-5} M)$ and DMBA.$(2{\times}10^{-5} M)$. DHEA-induced hepatotoxicity in rats was examined using lactate dehydrogenase (LDH) release as an indicator of cytotoxicity. DHEA exhibit no significant increase in LDH release compared with the control at 18 h. These data suggest that nontoxic concentration of DHEA does not affect the DNA excision repair process, but it probably influence the enzymatic system responsible for the metabolic activation of procarcinogens and thereby decreases the amount of the effective DNA adducts formed by the ultimate reactive carcinogenic species.

• Journal of Microbiology and Biotechnology
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• 제31권10호
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• pp.1343-1349
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• 2021

Cockroaches live in places where various pathogens exist and thus are more likely to use antimicrobial compounds to defend against pathogen intrusions. We previously performed an in silico analysis of the Periplaneta americana transcriptome and detected periplanetasin-5 using an in silico antimicrobial peptide prediction method. In this study, we investigated whether periplanetasin-5 has anticancer activity against the human leukemia cell line K562. Cell growth and survival of K562 cells treated with periplanetasin-5 were decreased in a dose-dependent manner. By using flow cytometric analysis, acridine orange/ethidium bromide (AO/EB) staining and DNA fragmentation, we found that periplanetasin-5 induced apoptotic and necrotic cell death in leukemia cells. In addition, these events were associated with increased levels of the pro-apoptotic proteins Fas and cytochrome c and reduced levels of the anti-apoptotic protein Bcl-2. Periplanetasin-5 induces the cleavage of pro-caspase-9, pro-caspase-8, pro-caspase-3, and poly (ADP-ribose) polymerase (PARP). The above data suggest that periplanetasin-5 induces apoptosis via both the intrinsic and extrinsic pathways. Moreover, caspase-related apoptosis was further confirmed by using the caspase inhibitor carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone (Z-VAD-FMK), which reversed the periplanetasin-5-induced reduction in cell viability. In conclusion, periplanetasin-5 caused apoptosis in leukemia cells, suggesting its potential utility as an anticancer therapeutic agent.

• The Journal of Asian Finance, Economics and Business
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• 제8권12호
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• pp.211-222
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• 2021

Green economy, also known as sustainable economy, is a current development trend in which consumers prefer products that are wholly or partly derived from materials of biological origin since they have become more concerned about their health and the environment in which they live. This study aims to examine consumer behavior toward bio-based products with three key goals in mind. First, it helps to understand the perception of consumers toward Bio-based products. Second, it properly helps consumers be aware of products derived from materials of biological origin so that the consumer can make purchasing decisions to protect their health and contribute to the protection of the environment. Third, the study on consumer behavior towards bio-based products will provide a more accurate view and assessment to companies looking to develop Bio-based products. Based on that, the research is carried out through surveying, collecting data from consumers, and then using the deductive approach, descriptive statistics, and quantitative method analysis. The results demonstrated that a positive relationship and a direct impact are established between the variables of Attitude and Social Norms and the Purchase Intention toward Bio-based products. Furthermore, the findings reveal that customers have positive feelings towards bio-based products in terms of trust, knowledge, and the environment.