• Herbal Formula Science
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• v.21 no.2
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• pp.63-71
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• 2013

Objectives : Artemisia princeps is used as moxa in moxibustion and traditional herbal medicine. And its extracts or compounds is known to have an efficacy of antioxidant, anti-diabete, anti-cancer, anti-inflammation and neuroprotection. This study was performed to investigate the cytoprotective effect of Artemisia princeps extract (APE) against arachidonic acid (AA)+iron-induced oxidative stress on HepG2 cell. Methods : The effects of APE on cell viability has been assessed using MTT assay. And flow cytometric analysis was performed to estimate APE's effects on mitochondrial function. To investigate its underlying mechanism, related protein was analysed by using immunoblot analysis. Results : Treatment of APE increased relative cell viability, prevented a decline of B-cell lymphoma-extra large (Bcl-xL) and cleavage of poly(ADP-ribose) polymerase (PARP) and procaspase-3, and also protected mitochondrial membrane permeability (MMP) against oxidative stress induced by AA+iron. In addition, APE treatment increased phosphorylation of AMP-activated protein kinase (AMPK) exerts a cytoprotective effect. Conclusions : This results demonstrate that APE has an ability to activation of AMPK which protects cells from AA+iron-induced oxidative stress and restores MMP.

• Journal of Korean Medical classics
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• v.21 no.1
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• pp.123-141
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• 2008

Objective Classification of herbal formulas through the analysis of compositional herb's is a suitable method in the aspects of the effective applications of herbal formulas. However, these classification methods have some problems in dealing with lots of herbal formulas because the estimations of herbal formula's effects are dependent upon one's memory. In this study, we aimed to establish the effective methodology to elicit the classified herbal formula's chart by introducing the DB systems without interfering with non-standard terms. Method : We entered the herbs informations of the composition of herbal formulas into database, made an alias tables of corresponding herbs, and achieved standardization of herb's informations. Using these databases, we made the classified herbal formula's chart according to the presence and the treatment informations of herbs. Results By analyzing the herbal formula into the set of compositional herbal elements, we could systemically express the parents and children herbal formula at once according to search terms. We provided the advanced searching tools entering the name of herbal formula and compositional herb together. Through these searching methods, it is facilitated to grasp the classified herbal formula's chart according to the addition and reduction of compositional herbs in Dong-uibogam(東醫寶鑑) and Bangjehak(方劑學)

• Honam Mathematical Journal
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• v.34 no.3
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• pp.311-326
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• 2012

The purpose of this paper is to introduce and investigate two new classes of generalized Bernoulli and Apostol-Bernoulli polynomials based on the definition given recently by the authors [29]. In particular, we obtain a new addition formula for the new class of the generalized Bernoulli polynomials. We also give an extension and some analogues of the Srivastava-Pint$\acute{e}$r addition theorem [28] for both classes. Finally, by making use of the new adition formula, we exhibit several interesting relationships between generalized Bernoulli polynomials and other polynomials or special functions.

• Korean Journal of Food Science and Technology
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• v.38 no.1
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• pp.75-81
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• 2006

Effects of medicinal herbs and bee propolis on pork quality were assessed using formulae A (control), B (boiling water extraction with propolis), and C (boiling water extraction without propolis). Seasoning sauce was made with medicinal herb, spices, total flavonoid, and soy sauce with/without 0.4% propolis (21.8 mg/g), mixed with pork, and stored at low temperature $(4{\pm}1^{\circ}C)$ for 20 days. In formula B peroxide value and thiobarbituric acid content increased with increasing storage period. Formula B showed highest Volatile Basic Nitrogen (VBN) and lowest microbial counts, followed by formulae C and A, receiving higher scores for taste and fragrance.

• Herbal Formula Science
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• v.27 no.1
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• pp.87-100
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• 2019

Objective : This study's purpose was to review the clinical studies of Mahwang-tang (MHT). Method : We searched ten clinical studies of MHT using KISS, RISS, NAVER, PUBMED, Science Direct. Ten papers were sorted by 4 topics, as influenza, pediatric febrile symptoms, contact dermatitis, and adjuvant for chronic hepatitis C. At last we analyzed if these papers are consistent with the keywords of Shanghanlun provisions about MHT. Results : When summarizing these papers again by topic, there were 4 studies on influenza, 1 study on pediatric febrile symptoms, 1 study on contact dermatitis and 4 studies as an adjuvant for chronic hepatitis C. Conclusion : These studies were consistent with terms such as fever, headache, aversion to wind, body pain, pain in the lumbar, articular pain written in Shanghanlun provisions. In addition to this, research on anti-depressive effects of MHT is proceeding systematically. However, studies on nosebleeds and pulses are still underdeveloped and further studies are needed.

• Membrane and Water Treatment
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• v.10 no.1
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• pp.19-28
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• 2019

To minimize the impact of urbanization, accurate performance evaluation of Low Impact Development (LID) facilities is needed. In Korea, the method designed to evaluate large-scale non-point pollution reduction facilities is being applied to LID facilities. However, it has been pointed out that this method is not suitable for evaluating the performance of relatively small-scale installed LID facilities. In this study, a new design formula was proposed based on the ratio of LID facility area and contributing drainage area, for estimating the Stormwater Interception Ratio (SIR) for LID facilities. The SIR was estimated for bio-retentions, infiltration trenches and vegetative swales, which are typical LID facilities, under various conditions through long-term stormwater simulation using the LID module of EPA SWMM. Based on the results of these numerical experiments, the new SIR formula for each LID facility was derived. The sensitivity of the proposed SIR formula to local rainfall properties and design variables is analysed. In addition, the SIR formula was compared with the existing design formula, the Rainfall Interception Ratio (RIR).

• Preventive Nutrition and Food Science
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• v.22 no.3
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• pp.241-245
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• 2017

Aged garlic has been reported to possess beneficial pharmacological activities, including anti-stress and anti-fatigue properties, and to exert protective effects on the cardiovascular system and liver. Pine needles are widely used in folk medicine and as food additives owing to their pharmacological properties such as anti-aging and anti-inflammatory effects. It has long been known that combining certain phytochemicals with other phenols or organic acids can produce synergistic effects. Therefore, the purpose of this study was to develop an optimal formula of aged garlic with added pine needle powder for improved antioxidant activity using the statistical technique of response surface methodology. The antioxidant activities of aged garlic mixed with pine needle powder were confirmed by measuring oxygen radical absorbance capacity and total polyphenol content. An optimized antioxidant formula was identified that contained 5.08 g aged garlic and 1.97 g pine needle powder. The antioxidant activities of the mixture prepared using this optimal formula were significantly higher than the predicted values according to an additive model. Hence, this study confirms that the addition of pine needle powder to aged garlic can improve its antioxidant activity. This study demonstrated an optimal mixing ratio to produce an aged garlic product with improved functionality through the addition of pine needle powder that could be successfully employed by the food industry to prepare functional foods.

• Honam Mathematical Journal
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• v.41 no.2
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• pp.403-420
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• 2019

The Helmholtz equation represents acoustic or electromagnetic scattering phenomena. The Method of Lines are known to have many advantages in simulation of forward and inverse scattering problems due to the usage of angle rays and Bessel functions. However, the method does not account for the jump phenomena on obstacle boundary and the approximation includes many high order Bessel functions. The high order Bessel functions have extreme blow-up or die-out features in resonance region obstacle boundary. Therefore, in particular, when we consider shape reconstruction problems, the method is suffered from severe instabilities due to the logical confliction and the severe singularities of high order Bessel functions. In this paper, two approximation formulas for the Helmholtz equation are introduced. The formulas are new and powerful. The derivation is based on Method of Lines, Huygen's principle, boundary jump relations, Addition Formula, and the orthogonality of the trigonometric functions. The formulas reduce the approximation dimension significantly so that only lower order Bessel functions are required. They overcome the severe instability near the obstacle boundary and reduce the computational time significantly. The convergence is exponential. The formulas adopt the scattering jump phenomena on the boundary, and separate the boundary information from the measured scattered fields. Thus, the sensitivities of the scattered fields caused by the boundary changes can be analyzed easily. Several numerical experiments are performed. The results show the superiority of the proposed formulas in accuracy, efficiency, and stability.

• Journal of the Korean Mathematical Society
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• v.49 no.5
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• pp.977-991
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• 2012

Let (M,F) and (M',F') be two foliated Riemannian manifolds with M compact. If the transversal Ricci curvature of F is nonnegative and the transversal sectional curvature of F' is nonpositive, then any transversally harmonic map ${\phi}:(M,F){\rightarrow}(M^{\prime},F^{\prime})$ is transversally totally geodesic. In addition, if the transversal Ricci curvature is positive at some point, then ${\phi}$ is transversally constant.

• Journal of the Korean Institute of Telematics and Electronics
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• v.24 no.5
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• pp.740-746
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• 1987

In calculating resonant frequencies of a microstrip resonator the effect of the stray field at resonator edges has been neglected in most publications. The formula for resonant frequencies therefore provided inaccurate results. In the paper the effective dimension and the dynamic dielectic constant of a resonator are defined and obtained for more accurate resonant frequencies and qualty factor by including the effect of stray fields. Theoretical results obtained from the new formula show good agreement with experimental results. In addition, the effect on resonant modes of the distance and coupling angle between the microstrip line and the resonator is also observed.