• Journal of the Korean Association of Geographic Information Studies
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• v.13 no.4
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• pp.78-90
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• 2010

This research tried to suggest a method of DB construction in the field using evaluation variables and Mobile GIS focusing on Changwon City as a leading study to encourage walking and biking in everyday life. First, twenty evaluation variables of WEs(walking environments) were selected through the literature review, and also scored separately. Second, the field survey-DB of each variable was built effectively using Mobile GIS. Finally, WEs were evaluated synthetically based on the obtained data. The results of this research are summarized as follows. While the WE of the zones located in the fringe of Changwon square were generally got a high score as over 42, other zones located in detached or row house area were evaluated relatively highly bad. Findings from this research will help in determining the zone required improvement of WEs or easy access to main destination such as a park, shopping center, school, etc. and also selecting variables of WEs, needed an intensive improvement, in the selected zone after comparing the results of field and questionnaire survey. Furthermore, those will be used as a means of decision making support for planing, designing and maintaining of WEs to promote people's physical activity in their daily lives.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.42 no.11
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• pp.33-40
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• 2005

This paper describes a design of FFT/IFFT Core(FFT256/2k), which is an essential block in terrestrial DMB modem. It has four operation modes including 256/512/1024/2048-point FFT/IFFT in order to support the Eureka-147 transmission modes. The hybrid architecture, which is composed of R2SDF and R2SDC structure, reduces memory by $62\%$ compared to R2SDC structure, and the SQNR performance is improved by TS_CBFP(Two Step Convergent Block Floating Point). Timing simulation results show that it can operate up to 50MHz(a)2.5-V, resulting that a 2048-point FFT/IFFT can be computed in 41-us. The FFT256/2k core designed in Verilog-HDL has about 68,400 gates and 58,130 RAM. The average power consumption estimated using switching activity is about 113-mW, and the total average SQNR of over 50-dB is achieved. The functionality of the core was fully verified by FPGA implementation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.9
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• pp.290-301
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• 2017

This research aimed to develop problem creating worksheets as a teaching & learning material for problem solving activities and assess its effectiveness. Activity worksheets for creative problem development were established. The effectiveness of the problem-creating classes taught to gifted students in invention was evaluated. In addition, effective strategies for encouraging problem creating and question making in teaching & learning processes were explored. The creative problem identification activity consisted of 5 steps, which are idea creation, convergence, execution, and evaluation. The results showed that elementary and middle school students taught in the classes using this problem-identification worksheet were highly satisfied with the program. This study concluded that it requires an educational environment, government level collaboration, and support to create a mature social atmosphere and educational environment motivating students to keep asking questions and identify problems. Through continual modification, additional ongoing efforts to increase the credibility and the quality of the worksheets as a creative problem solving and learning tool will be needed.

• Korean Journal of Health Education and Promotion
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• v.22 no.2
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• pp.195-213
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• 2005

Objectives: This study aims to determine fostering stress and mental health state that mothers of handicapped children perceive as primary care givers and to analyze their demand for information assistance in order to release their stress so that it can provide materials that contribute to establishment of assistance system for families with handicapped children. Methods: The research subjects were 340 mothers whose children went to a nursery for special children, 3 general nurseries and 6 special schools in Daegu, and the data were collected using structures questionnaires. The survey analyzed mothers' fostering stress, their demand for fostering information assistance, children's daily activity abilities. Component concepts of each scale was validated by adopting confirmatory factor analysis, and factors affecting demand for fostering information assistance were analyzed by adopting covariance structural analysis. Results: Younger mothers tend to have higher demand for information, and mothers with younger children or children with double handicaps also have higher demand. Mothers under 30 have the lowest demand for public health and medical care assistance and for home and community life assistance, while mothers with children with physical handicaps have the highest. The validity of component concepts was verified by categorizing as cognitive structure models fostering stress, information demand, children's daily activity abilities, and their appropriateness was evaluated through confirmatory factor analysis using structural equation modelling. And then, GFI (more than 0.9), CFI (more than 0.9), TLI (more than 0.9) and RMSAE (less than 0.08) were used to evaluate the appropriateness. It was found that all the component concepts are valid, as every item is within appropriate range. The result of analyzing information demand demonstrated that children's handicap levels significantly affect their mothers' mental health, while fostering stress significantly affect mothers' metal health, information demand. As well, it was confirmed that mothers' mental health has a significant effect on information demand. Conclusions: Therefore, to reduce special children's mothers' uncertainty, helplessness and fostering burden, it is necessary to provide them with information on children's challenges, development and fostering and to offer them quality public health, medical care and welfare assistance along with family and local community life assistance.

• School Mathematics
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• v.4 no.3
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• pp.375-399
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• 2002

When a curriculum change is being an issue, the editorships and the promotive directions reflect to supplement the social requests. However it is often criticized that such changes in the textbook itself are not satisfactory enough as to coherent to the editoships. And we set the following research questions; (1) One of the most important changes in the new 7th curriculum is to encourage the students' activities. We checked if it is well suited in the new textbooks. (2) Often textbook itself is not important In class, while instructor or students want something else other than the one suggested in the textbook. We asked 187 teachers how they use the textbooks in class. To answer (1), we checked up the introductory - activity - contents with 7 categories, which are ${\circled1}$ of real life sources ${\circled2}$ in use of concrete manipulative ${\circled3}$ in use of computers or calculators ${\circled4}$ in use of historical resources ${\circled5}$ stimulating to recall a relevant previous knowledges ${\circled6}$ of coherence between the activity and the exploratory contexts. ${\circled2}$ were increased, rewarding to the decrease of ${\circled5}$, in the new textbooks, while changes in ${\circled3}$ and ${\circled4}$ were not enough to talk about increments. Especially slight decrease in ${\circled6}$ were detected and it seemed to attribute to the unmatchable use of ${\circled1}$ and ${\circled2}$ with the explanation of mathematical subjects, which also implies how difficult to match ${\circled1}$ and ${\circled2}$ with ${\circled6}$. Analyzing the reponses of (2), about 70% of the teachers used the introductory activities in the textbook, which led better attention of sudents, while 30% of teachers do not use it because they felt that its inroductory activities had not been adequate for their purposes. Teachers counted inadequacy reasons for not being helpful in class, lack of time or lack of support of students, etc. Those teachers use introductory activities invented of their own for classes. As some results of the study, we suggest firstly that authors of textbooks have to get more informations to provide ways to entcourage students' interest in mathematics classes. The ways must be practical and brain storming as well as More use of computers and calculators and mathematical history are expected. Secondly, we are emphasizing the feedbacks between the textbook authors and the users(teachers and students) through internet. Which, we anticipate, will get better communications between them and be a good foundations of continuous modifications of textbooks.

• Biomedical Science Letters
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• v.9 no.4
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• pp.177-181
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• 2003

The baculovirus/Spodoptera frugiperda (Sf) cell system has become popular for the production of large amounts of the human erythrocyte glucose transporter, GLUT1, heterologously. However, it was not possible to show that the expressed transporter in insect cells could actually transport glucose. The possible reason for this was that the activity of the endogenous insect glucose transporter was extremely high and so rendered transport activity resulting from the expression of exogenous transporter very difficult to detect. Sf21-AE cells are commonly employed as the host permissive cell line to support the baculovirus AcNPV replication and protein synthesis. The cells grow well on TC-100 medium that contains 0.1 % D-glucose as the major carbon source, strongly suggesting the presence of endogenous glucose transporters. However, unlike the human glucose transporter, very little is known about properties of the endogenous sugar transporter(s) in insect cells. Thus, the uptake of 2-deoxy-D-glucose (2dGlc) by Sf21-AE cells and the inhibition of 2dGlc transport in the insect cells by fructose and cytochalasin B were investigated in the present work. The binding assay of cytochalasin B was also performed, which could be used as a functional assay for the endogenous glucose transporter(s) in the insect cells. Sf21-AE cells were infected with the recombinant virus AcNPV-GT or no virus, at a multiplicity of infection (MOI) of 5. Infected cells were resuspended in PBS plus and minus 300 mM fructose, and plus and minus 20 $\mu$M cytochalasin B for use in transport assays. Uptake was measured at 28$^{\circ}C$ for 1 min, with final concentration of 1 mM deoxy-D-glucose, 2-[1,2-$^3$H]- or glucose, L-[l,$^3$H]-, used at a specific radioactivity of 4 Ci/mol. The results obtained demonstrated that the sugar uptake in uninfected cells was stereospecific, and was strongly inhibited by fructose but only poorly inhibitable by cytochalasin B. It is therefore suggested that the Sf21-AE glucose transporter has very low affinity for cytochalasin B, a potent inhibitor of human erythrocyte glucose transporter.

• Journal of Korean Academy of Nursing
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• v.17 no.1
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• pp.64-78
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• 1987

This study is attempt to submit a basic material to help the efficient nursing management which supports and to understand the alienation which they percieve social-psychologically and physical aging bringing about the phf·sical powerlessness, to understand the old people in hospitals and in community and should build up their health. The data collection of the study which has been done on Sept. 7 to Sept. 20, 1986 is objected to 300 people of 65 years old of age or more of male and female who are staying at home. Analysis of the Data was done by use of percentage, t-test, ANOVA and Pearson Correlation Coefficients. The results of study are summerized as follows: 1. According to each age group of old people(p= .0008), family living together concreteness (p=.0000), the level of education (p=.0020), how much they are participating in leisure activity (p=.0001), whether they have mate or not (p=.0000), whether they have religion or not (p=.0000), the level of alienation showed difference statistically. Also, according to sex (p=.4315), whether they have income or not (p=.1197), the level of alienation did not show any difference statistically. 2. According to each age group of old people (p=.0000), family living together concreteness (p=.0060), the level of education (p=.0000), sex (p=.0000), whether they have mate or not (p=.0000), whether they have religion or not (p=.0067), whether they have income or not (p=.0000), the level of physical aging showed difference statistically. Also, according to how much they are participating in leisure activity, the level of physical aging did not show any difference statistically (p=4879). 3. The level of alienation and physical aging in old people had positive correlation (r=.5436, p<.001). From the above result, the level of social, psychological alienation and physical aging showed high for the old who had no mate, no religion, low in their educational level, living separately' with the family and for those who do not participate much in the leisure activities, The old people who feel the social, psychological alienation can expedite the physical aging and physical aging can be result from social psychological loneliness and alienation. Therefore, for the successful aging of the old people in the community with these weak points, we should provide them with physical and emotional, psycho-logical support and care in the basis of understanding in socialization process and the character of the physical functional change.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.3
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• pp.1260-1269
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• 2011

The purpose of this study was to determine postoperative quality of life(QoL), thyroid specific symptoms(TSSs), self care compliance, anxiety and depression in patients with papillary thyroid cancer and to identify factors influencing their postoperative QoL. 154 patients were surveyed using structured questionnaires and data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation, and multiple regression with SPSS/WIN 18.0 program. The mean score of postoperative QoL in the subjects was 2.72 and the postoperative QoL score of social/family well being subscale showed the lowest score. Most of the subjects suffered from TSSs such as fatigue, cold intolerance, and mood swings. The most frequent activity for self care compliance was taking thyroid hormone(100%) and OPD follow up was the second activity(99.4%). Anxiety score was 45.3 indicating a medium level however 63% of the subjects were evaluated as depression status. Postoperative QoL in thyroid papillary cancer patients showed significantly negative correlations to TSSs, anxiety, and depression (r=-.573, p<.001; r=-.739, p<.001; r=-.742, p<.001). The factors influencing postoperative QoL were TSSs, anxiety, and depression, which explained about 64.9% of the variance. Thus to improve postoperative QoL in patients with papillary thyroid cancer, health care providers should relieve negative emotions related to long term cancer management, develop the support system and provide practical information to apply patients' physical, and psychological symptoms control.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.19-29
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• 1996

The neurological manifestations of AIDS include dementia, encountered even in the absence of opportunistic superinfection or malignancy. The AIDS Dementia Complex appears to be associated with several neuropathological abnormalities, including astrogliosis and neuronal injury or loss. How can HIV-1 result in neuronal damage if neurons themselves are only rarely, if ever, infected by the vitus\ulcorner In vitro experiments from several different laboratiories have lent support to the existence of HIV- and immune-related toxins. In one recently defined pathway to neuronal injury, HIV-infected macrophages/microglia as well as macrophages activated by HIV-1 envelope protein gp120 appear to secrete excitants/neurotoxins. These substances may include arachidonic acid, platelet-activating factor, free radicals (NO - and O$_2$), glutamate, quinolinate, cysteine, cytokines (TNF-${\alpha}$, IL1-B, IL-6), and as yet unidentified factors emanating from stimulated macrophages and possibly reactive astrocytes. A final common pathway for newonal suscepubility appears to be operative, similar to that observed in stroke, trauma, epilepsy, and several neurodegenerative diseases, including Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis. This mechanism involves excessive activation of N-methyl-D-aspartate (NMDA) receptor-operated channels, with resultant excessive influx of Ca$\^$2+/ leading to neuronal damage, and thus offers hope for future pharmacological intervention. This chapter reviews two clinically-tolerated NMDA antagonists, memantine and nitroglycerin; (ⅰ) Memantine is an open-channel blocker of the NMDA-associated ion channel and a close congener of the anti-viral and anti-parkinsonian drug amantadine. Memantine blocks the effects of escalating levels of excitotoxins to a greater degree than lower (piysiological) levels of these excitatory amino acids, thus sparing to some extent normal neuronal function. (ⅱ) Niuoglycerin acts at a redox modulatory site of the NMDA receptor/complex to downregulate its activity. The neuroprotective action of nitroglycerin at this site is mediated by n chemical species related to nitric oxide, but in a higher oxidation state, resulting in transfer of an NO group to a critical cysteine on the NMDA receptor. Because of the clinical safety of these drugs, they have the potential for trials in humans. As the structural basis for redox modulation is further elucidated, it may become possible to design even better redox reactive reagents of chinical value. To this end, redox modulatory sites of NMDA receptors have begun to be characterized at a molecular level using site-directed mutagenesis of recombinant subunits (NMDAR1, NMDAR2A-D). Two types of redox modulation can be distinguished. The first type gives rise to a persistent change in the functional activity of the receptor, and we have identified two cysteine residues on the NMDARI subunit (#744 and #798) that are responsible for this action. A second site, presumably also a cysteine(s) because <1 mM N-ethylmaleimide can block its effect in native neurons, underlies the other, more transient redox action. It appears to be at this, as yet unidentified, site on the NMDA receptor that the NO group acts, at least in recombinant receptors.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.9
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• pp.2097-2104
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• 2013

Scientific and technological research data is increasing exponentially and, Kisti(Korea Institute of Science and Technology Information) built and supported GSDC(Global Science experimental Data hub Center) depending on the needs processing large data computing and storage devices. Mobile web standards-based the MUPS was built for global community and services of gsdc to spreading mobile devices rapidly. And for analyze Operational status and system resources of GSDC at n this paper researched and implemented system resource monitor method of gsdc to mobile web environment, in this paper researched and implemented system resource monitor method of gsdc to mobile web environment. Research support system of GSDC operated by scientific linux. Sysstat resource monitoring tools create a daily report through sar(system analysis report), after sadc(system activity data collector) collected system resource utilization information. In this paper, sar reports designed and implemented in mobile web to can visualize in a mobile environment. We do not depend specific OS by implementation of the mobile web. So we are available in variety mobile OS. And through provided visual graph, this system can monitor easily and more conveniently then the existing system.