• Title/Summary/Keyword: Activation product

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A 3.3V/5V Low Power TTL-to-CMOS Input Buffer Controlled by Internal Activation Clock Pulse (활성 클럭펄스로 제어되는 3.3V/5V 저전력 TTL-to-CMOS 입력 버퍼)

  • Bae, Hyo-Kwan;Ryu, Beom-Seon;Cho, Tae-Won
    • Journal of IKEEE
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    • v.5 no.1 s.8
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    • pp.52-58
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    • 2001
  • This paper describes a TTL-to-CMOS input buffer of an SRAM which dissipates a small operating power dissipation. The input buffer utilizes a transistor structure with latch circuit controlled by a internal activation clock pulse. During the low state of that pulse, input buffer is disabled to eliminate dc current. Otherwise, the input buffer operates normally. Simulation results showed that the power-delay product of the purposed input buffer is reduced by 33.7% per one input.

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The Validation of Spreading Activation Model as Evaluation Methodology of Menu Structure: Eye Tracking Approach (메뉴 구조의 평가 방법론으로서 활성화 확산 모델의 타당성 검증: Eye-Tracking 접근 방법)

  • Park, Jong-Soon;Myung, Ro-Hae
    • Journal of the Ergonomics Society of Korea
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    • v.26 no.2
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    • pp.103-112
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    • 2007
  • This study was designed to validate Spreading Activation Theory (SAT) for an evaluation methodology for menu structure through Eye-Tracking approach. When a visual search is on the way, more eye fixations and time are necessary to visually process complex and vague area. From the aspect of recognition, well-designed menu structures were hypothesized to have fewer numbers of fixations and shorter duration because well-designed menu structures reflecting the users' mental model would be well matched with the product's menu structure, resulting in reducing the number of fixations and duration time. The results show that the shorter reaction times for SAT had significantly fewer numbers of fixation and shorter duration time as the hypothesis for this study stated. In conclusion, SAT was proved to be an effective evaluation methodology for menu structure with the eye tracking equipment. In addition, using SAT instead of the real performance experiment would be useful for designing user-centered systems and convenient information structures because SAT was proven to be the theoretical background for design and evaluation of menu structures.

Mechanisms involved in adenosine pharmacological preconditioning-induced cardioprotection

  • Singh, Lovedeep;Kulshrestha, Ritu;Singh, Nirmal;Jaggi, Amteshwar Singh
    • The Korean Journal of Physiology and Pharmacology
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    • v.22 no.3
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    • pp.225-234
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    • 2018
  • Adenosine is a naturally occurring breakdown product of adenosine triphosphate and plays an important role in different physiological and pathological conditions. Adenosine also serves as an important trigger in ischemic and remote preconditioning and its release may impart cardioprotection. Exogenous administration of adenosine in the form of adenosine preconditioning may also protect heart from ischemia-reperfusion injury. Endogenous release of adenosine during ischemic/remote preconditioning or exogenous adenosine during pharmacological preconditioning activates adenosine receptors to activate plethora of mechanisms, which either independently or in association with one another may confer cardioprotection during ischemia-reperfusion injury. These mechanisms include activation of $K_{ATP}$ channels, an increase in the levels of antioxidant enzymes, functional interaction with opioid receptors; increase in nitric oxide production; decrease in inflammation; activation of transient receptor potential vanilloid (TRPV) channels; activation of kinases such as protein kinase B (Akt), protein kinase C, tyrosine kinase, mitogen activated protein (MAP) kinases such as ERK 1/2, p38 MAP kinases and MAP kinase kinase (MEK 1) MMP. The present review discusses the role and mechanisms involved in adenosine preconditioning-induced cardioprotection.

Temperature Profile Analysis of $Ti5_Si_3$ in Self-Propagating High Temperature Synthesis (SHS 법에 의한 $Ti5_Si_3$의 합성시 온도 Profile 분석)

  • 김도경;이형직;김익진;이형복
    • Journal of the Korean Ceramic Society
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    • v.32 no.3
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    • pp.341-348
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    • 1995
  • An analysis of the use of temperature profiles in the determination of the kinetic parameters of combustion synthesis of Ti5Si3 were investigated. From profile analysis, an apparent activation energy of 12KJ/mol was calculated. The Maximum heating rate achieved during 10wt% Ti5Si3 reaction by the product dilution method was approximately $1.5\times$104 K/s. Coupling this value with the measured wave velocity of 7.02 cm/s yields a maximum thermal gradient of 2.14$\times$103 K/cm. The value of tr (=t*) was calculated to be 1.2$\times$10-1 s and the value of td (=tx) was calculated to be 32.89 s. Using the definition of t* and the measured wave velocity, the effective thermal diffusivity, $\alpha$, was calculated to be 0.59$\times$10 $\textrm{cm}^2$/s. From these analysis, the power function, G, was also calculated.

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Tumour Promoting Activity of Plants Used in Malaysian Traditional Medicine

  • Ilham, M.;Yaday, M.;Norhanom, A.W.
    • Natural Product Sciences
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    • v.1 no.1
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    • pp.31-42
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    • 1995
  • One hundred plants in 43 families used in Malaysian traditional medicine were screened for tumour promoting activity using two methods, the technique of activation of latent Epstein-Barr Virus (EBV) in Raji cells and the irritation test on mouse ear. Extracts of only eight plants belonging to the Euphorbiaceae were found to possess EBV activation factor and to give a positive irritation test in mouse ear. These plants included Euphorbia tirucalli L., E. splendes, Jatropha podagrica, J. gossypyfolia L., Pedilanihus tithymaloides (L.) Poitt., Croton argyratus Bl., Exocoecaria agallocha L. and Codiaeum variegatum (L.) Bl. Seven of these plants are used internally in Malaysian traditional medicine. As such, they pose potential danger in the promotion of initiated cells of the mucosal tissue towards disease. Further studies are required to assess the epidemiological impact of these plants in the development of disease.

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Peculiarities of SHS and solid state synthesis of $ReBa_{2}Cu_{3}O_{7-x}$ materials

  • Sho, Dea-Wha;Li, Yingmei;Cho, Yong-Joon;Kim, Tae-Wan;Korobova, N.;Isaikina, O.;Mansurov, Z.;Baydeldinova, A.;Ksandopoulo, G.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.07a
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    • pp.620-623
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    • 2001
  • The peculiarities of using Self-propagating High-temperature Synthesis (SHS) and solid state phase synthesis for production of high temperature superconductor materials are discussed. Oxide superconductors with general formula $ReBa_2$$Cu_3$$O_{7-x}$ (Re= Y, Yb, Sm, Nd) have been made with using barium oxide initial powder instead of traditional barium carbonate. X-ray powder diffraction showed a single phase orthorhombic perovskite structure was produced in all reactions. Phenomena observed during the grinding of the reactant mixture are presented. Mechano-chemical activation - as a pretreatment of the reactant mixture - strongly influences the kinetic parameters, the reaction mechanism, and the composition and structure of the final product.

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KINETIC MODELING STUDY OF A VOLOXIDATION FOR THE PRODUCTION OF U3O8 POWDER FROM A UO2 PELLET

  • Jeong, Sang-Mun;Hur, Jin-Mok;Lee, Han-Soo
    • Nuclear Engineering and Technology
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    • v.41 no.8
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    • pp.1073-1078
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    • 2009
  • A kinetic model for the oxidation of a $UO_2$ pellet to $U_3O_8$ powder has been suggested by considering the mass transfer and the diffusion of oxygen molecules. The kinetic parameters were estimated by a fitting of the experimental data. The activation energies for the chemical reaction and the product layer diffusion were calculated from the kinetic model. The oxidation conversion of a $UO_2$ pellet was simulated at various operating conditions. The suggested model explains the oxidation behavior of $UO_2$ well.

Effect of Ga, Nb Addition on Disproportionation Kinetics of Nd-Fe-B Alloy

  • Kwon, H.W.;Yu, J.H.
    • Journal of Magnetics
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    • v.14 no.4
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    • pp.150-154
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    • 2009
  • The effect of Ga and, Nb addition on the kinetics and mechanism of the disproportionation of a Nd-Fe-B alloy were investigated by isothermal thermopiezic analysis (TPA) using $Nd_{12.5}Fe_{(81.1-(x+y))}B_{6.4}Ga_xNb_y$ (x=0 and 0.3, y= 0 and 0.2) alloys. The addition of Ga and Nb retarded the disproportionation kinetics of the Nd-Fe-B alloy significantly, and increased the activation energy of the disproportionation reaction. The disproportionation kinetics of the $Nd_{12.5}Fe_{(81.1-(x+y))}B_{6.4}Ga_xNb_y$ alloys measured under an initial hydrogen pressure of 0.02 MPa were fitted to a parabolic rate law. This suggested that during the disproportionation of $Nd_{12.5}Fe_{(81.1-(x+y))}B_{6.4}Ga_xNb_y$ alloys with an initial hydrogen pressure of 0.02 MPa, a continuous disproportionation product is formed and the overall reaction rate is limited by the diffusion of hydrogen atoms (or ions).

Natural Products Targeting Wnt/β-catenin Signaling Pathway

  • Kim, Donghwa;Lee, Sang Kook
    • Natural Product Sciences
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    • v.26 no.2
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    • pp.109-117
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    • 2020
  • The canonical Wnt/β-catenin signaling pathways play an important role in the embryonic development, cell proliferation, differentiation, and adhesion. Therefore, the abnormal activation and repression have been associated with uncontrolled homeostasis in human tissues. In particular, the activation of Wnt signaling is highly correlated with a diverse of diseases including cancer. On this regard, a strategy for targeting Wnt/β-catenin signaling has been employed in the discovery and development of antitumor agents. Herein, the evolution of Wnt signaling and the Wnt inhibitors derived from natural products were briefly summarized in the drug discovery of anticancer agents.

A Kinetic Study of Thermal Degradations of Chitosan/Polycaprolactam Blends

  • Liao, Shen-Kun;Hung, Chi-Chih;Lim, Ming-Fung
    • Macromolecular Research
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    • v.12 no.5
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    • pp.466-473
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    • 2004
  • We have used FT-IR spectra to explain the effects of hydrogen bonding between chitosan and polycaprolactam (PA6). A dynamic mechanical analysis study suggested that the optimum chitosan and PA6 miscibility under the conditions of this experiment were obtained at a blending ratio of 40:60. We studied the thermal degradation of chitosan blended with PA6 (chitosan/PA6) by thermogravimetric analysis and kinetic analysis (by the Ozawa method). Dry chitosan and PA6 exhibited a single stage of thermal degradation and chitosan/PA6 blends having> 20 wt% PA6 exhibited at least two stages of degradation. In chitosan/PA6 blends, chitosan underwent the first stage of thermal degradation; the second stage proceeded at a temperature lower than that of PA6, because the decomposition product of chitosan accelerated the degradation of PA6. The activation energies of the blends were between 130 and 165 kJ/mol, which are also lower than that of PA6.