• 생약학회지
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• 제49권4호
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• pp.341-348
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• 2018

This study was carried out to obtain the basic informations for phenolic compounds by various sections of Acanthopanacis Caulis. The phenolic compounds of Korean Acanthopanacis bark and lignum (Acanthopanax divaricatus var. albeofructus, Acanthopanax koreanum) were measured by the HPLC analysis. The content of total phenolic components of Acanthopanax koreanum bark (1.532%) was about 9.9 times higher than that of Acanthopanax koreanum lignum (0.155%). And also, The content of total phenolic components of Acanthopanax divaricatus var. albeofructus bark (0.420%) was about 2.8 times higher than that of Acanthopanax divaricatus var. albeofructus lignum (0.149%). Eleutheroside E, a functional ingredient of Acanthopanacis Caulis, showed 3.6 times higher contents of Acanthopanax koreanum bark (0.144%) than Acanthopanax koreanum lignum (0.040%). In the case of Acanthopanax divaricatus var. albeofructus bark (0.129%), the content of the eleutheroside E was 1.7 times higher than that of the Acanthopanax divaricatus var. albeofructus lignum (0.074%).

• Natural Product Sciences
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• 제16권3호
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• pp.198-201
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• 2010

Acanthopanax divaricatus var. albeofructus is one of the indigenous medicinal plant and the fruits of Acanthopanax spp. used as a remedial for "wipe out evil wind". Two anthocyanin were isolated from the fruits of Acanthopanax divaricatus var. albeofructus. Their structures were elucidated as cyanidin 3-lathyroside (1) and cyanidin 3-galactoside (2) by chemicophysical and spectroscopic analysis. And also, four chemical, syringin, chlorogenic acid, caffeic acid and acanthoside D were identified. Both anthocyanide were isolated for the first time from Acanthopanax species. cyanidin 3-lathyroside is one of the rare anthocyanin in natural resources.

• 약학회지
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• 제48권4호
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• pp.236-240
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• 2004

Acanthopanax species (Araliaceae) traditionally has been used as analgesics, stimulant of immune system, and replenishment of body functions. Acanthopanax divaricatus var. albeofructus is indigenous plant to Korea. The antioxidant activities of compounds from A divaricatus var. albeofructus were determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and thiobarbituric acid reactive substance (TBARS) assay on human plasma low-density lipoprotein (LDL). The triterpenoid and lignan constituents from this plant showed antioxidant activities and the lignan, l-sesamin exhibited the most potent antioxidant activity in Cu$^{2+}$ -induced LDL oxidation.n.

• Journal of Applied Biological Chemistry
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• 제57권4호
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• pp.337-340
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• 2014

본 연구에서는 지리산오가피와 흰털오가피의 항산화 및 항염증 활성의 차이를 알아보기 위해 총 폴리페놀 및 플라보노이드 함량, ABTS 및 DPPH 라디칼 소거능, FRAP assay를 이용한 환원력을 비교 조사하였고, mouse의 대식세포인 Raw 264.7 cell에 LPS를 이용하여 자극시킨 후 생성되는 NO의 함량을 비교하였다. 총 폴리페놀 및 플라보노이드 함량은 흰털오가피가 유의하게 높은 것으로 나타났으나 그 차이가 크지 않으며 ABTS 및 DPPH 라디칼 소거능과 FRAP 방법을 이용한 환원력에서는 두 오가피 종에서 차이가 없는 것으로 나타났다. 항염증 활성을 비교하기 위해 확인한 NO 생성양은 지리산오가피가 고농도 처리시 유의하게 항염증 활성이 높은 것으로 나타났다.

• 생약학회지
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• 제48권1호
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• pp.5-9
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• 2017

This study was carried out to obtain the basic information that can be used to index Acanthopanax in eleven species of China and Korea. The phytochemical components from the berry of Acanthopanax species, were measured by the HPLC analysis. Protocatechuic acid, eleutheroside B, eleutheroside E, scopolin, rutin, hyperoside, chiisanoside, oleanolic acid were found in ethanol extracts from the berry of Acanthopanax species. Total phenolic compound of Acanthopanax sessiliflorum f. chungbuensis berry (0.682%) was about seven times higher than those of Acanthopanax divaricatus f. distigmatis berry (0.091%). As a result, the order of the eleutheroside E content was 1) Acanthopanax sessiliflorum f. chungbuensis (0.554%), 2) A. divaricatus var. albeofructus (0.501%), 3) A. divaricatus f. flavi-flos (0.452%). And also, the order of the chiisanoside content was 1) Acanthopanax senticosus var. subinermis (8.434%), 2) A. seoulense (0.94%), 3) A. divaricatus f. flavi-flos (0.798%).

• Current Research on Agriculture and Life Sciences
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• 제31권2호
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• pp.88-93
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• 2013

The cultivation methods of Acanthopanax in Korea need to be optimized. Hence, this study investigated the effect of different fertilizer ratios and planting dates on the growth and acanthoside D content of two (2) Acanthopanax species. The current recommended fertilizer rate of 10.5-8.5-8.5 $kg/ha^-$ ($N-P_2O_5-K_2O$, respectively) produced the best plant growth of Acanthopanax. For the first year, the acanthoside D content resulting from the 2P (2x phosphate) rate was higher than that from the other fertilizer ratios, yet there were no significant differences resulting from the various treatments for either Acanthopanax divaricatus or Acanthopanax koreanum. Similarly, for the second year, there were no significant differences in the acanthoside D content resulting from the various fertilizer ratios, although for both species the acanthoside D content resulting from the 2P rate was slightly higher than that from the other treatments. Therefore, the results indicated that doubling the amount of phosphate increased the acanthoside D content. Plus, the optimum planting date with respect to growth and productivity for Acanthopanax divaricatus was identified as April 15.

• 약학회지
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• 제48권1호
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• pp.99-103
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• 2004

Acanthopanax species (Araliaceae) has been traditionally used as analgesics, stimulants of immune system, and replenishment of body functions. Acanthopanax divaricatus var. albeofructus is a indigenous plant in Korea. The anti-lipid peroxidation activities of the loaves and root bark extracts of A divaricatus var. albeofructus were determined. Activities of MeOH extracts were examined in vitro and in vivo with control group intoxicated by carbon tetrachloride. Both extracts showed significant inhibitory effects on the lipid peroxidation.

• Natural Product Sciences
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• 제12권3호
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• pp.119-121
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• 2006

Four 3,4-seco-lupane trierpenoids were isolated from the MeOH extract of the leaves of Acanthopanax divaricatus forma flavi-flos Yook by using various column chromatography. The chemical structures of isolates were identified as chiisanogenin, chiisanoside, isochiisanoside and 11-deoxyisochiisanoside on the basis of physico-chemical and spectroscopic date($^1H-NMR,\;^{13}C-NMR$M$, 2D-NMR and FAB-MS). These compounds were isolated for the first time from A. divaricatus forma flavi-flos.

• Mycobiology
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• 제43권3호
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• pp.366-370
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• 2015

Acanthopanax divaricatus, a member of the Araliaceae family, has been used as an invigorant in traditional Korean medicine. During disease monitoring, a stem with small, irregular, brown lesions was sampled at a farm in Cheonan in 2011. The symptoms seen were sunken cankers and reddish-brown needles on the infected twig. The isolated fungal colonies were whitish, having crenated edges and aerial mycelium on the surface, and with black gregarious fruiting bodies. The reverse plate was creamy white. Conidia were $17{\sim}22{\times}3.5{\sim}4.2{\mu}m$, fusiform, 4-septate, and straight to slightly curved. The nucleotide sequence of the partial translation elongation factor 1 alpha gene of the fungal isolate, shares 99% sequence identity with that of known Pestalotiopsis ellipsospora. Based on the results of the morphological and molecular analyses, the fungal isolate was identified as P. ellipsospora. In Korea, this is the first report of canker on A. divaricatus.

• 한국약용작물학회지
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• 제21권1호
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• pp.39-44
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• 2013

This study was conducted to identify the effect of shading and pinching on growth and acanthoside-D content of Acanthopanax divaricatus var. albeofructus and A. koreanum Nakai. Different pinching heights showed no significant differences in terms of plant growth and acanthoside-D content but higher values showed that pinching A. divaricatus at 60 cm and A. koreanum at 30 cm favored good growth and higher fresh weight in the shoots. The content of acanthoside-D was not significantly affected by pinching heights. Also, no significant difference in acanthoside-D content was found between the lower and upper part of plant in the first year. However it was much higher in the lower part than the upper part in the second year, which indicated that the content of acanthoside-D was comparatively high in the lower part where lignification is much advanced. Shading showed benefits in terms of growth of A. divaricatus while only 50%-shading was favorable for A. koreanum to achieve superior growth. Overall, results indicated that shading had favorably affected the growth of the 2 Acanthopanax species while no-shading is better if we opt to achieve higher acathoside D content.