• Title/Summary/Keyword: Ablation

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3D CACT-assisted Radiofrequency Ablation Following Transarterial Chemoembolization for Hepatocellular Carcinoma: Early Experience

  • Jiao, De-Chao;Han, Xin-Wei;Wu, Gang;Ren, Jian-Zhuang
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7897-7903
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    • 2015
  • Background: To explored the value of 3D C-arm CT (CACT) guidance system in performing radiofrequency ablation (RFA) following transarterial chemoembolizationon (TACE) for hepatocellular carcinomas. Materials and Methods: RFA of hepatocellular carcinomas (HCC) were performed on 15 patients (21 lesions) with the assistance of CACT guidance system. Technical success, procedure time, complications and patient radiation exposure were investigated. The puncture performance level was evaluated on a five-point scale (5-1: excellent-poor). Complete ablation rate was evaluated after two months follow-up using enhanced CT scans. Results: The technical success rate of RFA procedure under CACT navigation system was 100 %. Mean total procedure time was $24.24{\pm}6.53min$, resulting in a mean effective exposure dose of $15.4{\pm}5.1mSv$. The mean puncture performance level rated for CACT guided RFA procedure was $4.87{\pm}0.35$. Complete ablation (CA) was achieved in 20 (95.2%) of the treated 21 tumors after the first RFA session. None of patients developed intra-procedural complications. Conclusions: 3D CACT guidance system enables reliable and efficient needle positioning by providing real-time intraoperative guidance for performing RFA on HCCs.

Processing Evaluations of the Eagle Glass Cutting Using Pico-second Laser (피코초 레이저를 이용한 Eagle Glass 절단 시 가공성 평가)

  • Lee, Sang Kyun;Lee, Young Gon;Kim, Jae Do
    • Journal of the Korean Society for Precision Engineering
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    • v.30 no.4
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    • pp.403-408
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    • 2013
  • In this paper, the characteristics of ablation processing of the eagle glass by pico-second laser are investigated. The laser ablation is used to process micro forms on materials. The ablation causes little thermal effect and little burr on the surface of eagle glass. In order to examine the characteristics of panic cracks, experiments are conducted under various cutting conditions such as a frequency of 600 kHz, laser powers, scan speeds and number of scan(NS). To minimize the panic cracks, the specimens are heated at $30^{\circ}C$, $45^{\circ}C$, and $60^{\circ}C$ for ten minutes respectively and then they are broken by hands. Laser powers, NS and scan speeds have an effect on glass cutting results. The ablation depths increase with an increase in the laser power and NS whereas the panic cracks decrease with an increase in scan speed. The high temperature on processed specimens reduces the panic cracks and makes good results of laser cutting. The optimal condition for eagle glass laser cutting is found to be at 30 W of laser power, 3 mm/s of scan speed and 500 of NS, respectively.

Study on the ablation structures of Carbon/Phenolic composites used PAN based carbon fiber (PAN계 탄소섬유를 이용한 Carbon/Phenolic 복합재의 삭마구조 특성 연구)

  • Im, Yeon-Su;Kim, Dong-Gyu;Park, In-Seo;Yun, Byeong-Il
    • Korean Journal of Materials Research
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    • v.4 no.3
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    • pp.339-348
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    • 1994
  • The study has been conducted to know ablation microstructures and characteristics in carbon /phenolic composites. Ablation properties depend on mole fraction of $H_2O$ and $C0_2$ gas which were produced by reaction between propellant and oxidizer. However, the results of this study shown that the ablation also depended on weaving structure, density of fabric, and tow size of carbon fiber. 3K 8HS fabric showed superior ablation resistance to others, 3K twill and 12K 8HS fabric structures.

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The Modelling of Carbon Plume by Pulsed-laser ablation Method (PLAD법에 의한 탄소 플라즈마의 모델링)

  • So, Soon-Youl;Chung, Hae-Deok;Lee, Jin;Park, Gye-Choon;Kim, Chang-Sun;Moon, Chae-Joo
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.05a
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    • pp.41-45
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    • 2006
  • The study on laser-ablation plasmas has been strongly interested in fundamental aspects of laser-solid interaction and consequent plasma generation. In particular, this plasma has been widely used for the deposition of thin solid films and applied to the semiconductors and insulators. In this paper, we developed and discussed the generation of carbon ablation plasmas emitted by laser radiation on a solid target, graphite. The progress of carbon plasmas by laser-ablation was simulated using Monte-Carlo particle model under the pressures of vacuum, 1 Pa, 10 Pa and 66 Pa. At the results, carbon particles with low energy were deposited on the substrate as the pressure becomes higher. However, there was no difference of deposition distributions of carbon particles on the substrate regardless of the pressure.

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Carbon Plume Modeling Assisted by Ar Plasmas (Ar 플라즈마 상태에서 운동하는 탄소 입자 모델링)

  • So, Soon-Youl;Lee, Jin;Chung, Hae-Deok;Yeo, In-Seon
    • Proceedings of the KIEE Conference
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    • 2005.07c
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    • pp.2163-2165
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    • 2005
  • A pulsed laser ablation deposition (PLAD) technique has been used for producing fine particle as well as thin film at relatively low substrate temperatures. However, in order to manufacture and evaluate such materials in detail, motions of plume particles generated by laser ablation have to be understood and interactions between the particles by ablation and gas plasma have to be clarified. Therefore, this paper was focused on the understanding of plume motion in laser ablation assisted by Ar plasma at 50(mTorr). Two-dimensional hybrid model consisting of fluid and particle models was developed and three kinds of plume particles which are carbon atom (C), ion $(C^+)$ and electron were considered in the calculation of particle method It was obtained that ablated $C^+$ was electrically captured in Ar plasmas by strong electric field (E). The difference between motions of the ablated electrons and $C^+$ made E strong and the collisional processes active.

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Theoretical Analysis on the Optimum Fluence for Copper Ablation with a 515 nm Picosecond Laser (515 nm 피코초 레이저를 이용한 구리 어블레이션 공정의 최적 에너지밀도에 대한 이론적 분석)

  • Shin, Dongsig;Cho, Yongkwon;Sohn, Hyonkee
    • Journal of the Korean Society for Precision Engineering
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    • v.30 no.10
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    • pp.1009-1015
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    • 2013
  • Ultra-short laser pulses are effective, when high requirements concerning accuracy, surface roughness and heat affected zone are demanded for surface structuring. In particular, picosecond laser systems that are suited to be operated in industrial environments are of great interest for many practical applications. This paper focused on inducing optimum process parameters for higher volume ablation rate by analyzing a relationship between crater diameter and optical spot size. In detail, the dependency of the volume ablation rate, penetration depth and threshold fluence on the pulse duration 8 ps and wavelength of 515 nm was discussed. The experimental results showed that wavelength of 515 nm resulted in less threshold fluence ($0.075J/cm^2$) on copper than IR wavelength ($0.3J/cm^2$). As a result, it was possible that optimum fluence for higher volume ablation rate was achieved with $0.28J/cm^2$.

Survey on Laser Ablation Micro-thruster for Small Satellites (소형 인공위성을 위한 레이저 삭마 미소 추력기 개발 현황)

  • Park, Young Min;Lee, Bok Jik
    • Journal of the Korean Society of Propulsion Engineers
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    • v.22 no.1
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    • pp.98-106
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    • 2018
  • With the advancement in technology, miniaturization, integration, and weight reduction of satellite components have become possible. In this regard, existing medium and large satellites have been replaced by small satellites. As the demand for small satellites increases, the need for micro-thrusters has emerged for precise attitude and position control. A laser ablation micro-thruster, which generates thrust by using ablation jets that offer a wide range of thrusts and low-impulse thrusts, is considered as an alternative for micro-thrusters in small satellites. The objective of the present study is to introduce configurations of the laser ablation micro-thruster and its research trend.

Selective Laser Direct Patterning of Indium Tin Oxide on Transparent Oxide Semiconductor Thin Films

  • Lee, Haechang;Zhao, Zhenqian;Kwon, Sang Jik;Cho, Eou Sik
    • Journal of the Semiconductor & Display Technology
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    • v.18 no.4
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    • pp.6-11
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    • 2019
  • For a wider application of laser direct patterning, selective laser ablation of indium tin oxide (ITO) film on transparent oxide semiconductor (TOS) thin film was carried out using a diode-pumped Q-switched Nd:YVO4 laser at a wavelength of 1064 nm. In case of the laser ablation of ITO on indium gallium zinc oxide (IGZO) film, both of ITO and IGZO films were fully etched for all the conditions of the laser beams even though IGZO monolayer was not ablated at the same laser beam condition. On the contrary, in case of the laser ablation of ITO on zinc oxide (ZnO) film, it was possible to etch ITO selectively with a slight damage on ZnO layer. The selective laser ablation is expected to be due to the different coefficient of thermal expansion (CTE) between ITO and ZnO.

Magnetic Resonance-Guided Focused Ultrasound : Current Status and Future Perspectives in Thermal Ablation and Blood-Brain Barrier Opening

  • Lee, Eun Jung;Fomenko, Anton;Lozano, Andres M.
    • Journal of Korean Neurosurgical Society
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    • v.62 no.1
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    • pp.10-26
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    • 2019
  • Magnetic resonance-guided focused ultrasound (MRgFUS) is an emerging new technology with considerable potential to treat various neurological diseases. With refinement of ultrasound transducer technology and integration with magnetic resonance imaging guidance, transcranial sonication of precise cerebral targets has become a therapeutic option. Intensity is a key determinant of ultrasound effects. High-intensity focused ultrasound can produce targeted lesions via thermal ablation of tissue. MRgFUS-mediated stereotactic ablation is non-invasive, incision-free, and confers immediate therapeutic effects. Since the US Food and Drug Administration approval of MRgFUS in 2016 for unilateral thalamotomy in medication-refractory essential tremor, studies on novel indications such as Parkinson's disease, psychiatric disease, and brain tumors are underway. MRgFUS is also used in the context of blood-brain barrier (BBB) opening at low intensities, in combination with intravenously-administered microbubbles. Preclinical studies show that MRgFUS-mediated BBB opening safely enhances the delivery of targeted chemotherapeutic agents to the brain and improves tumor control as well as survival. In addition, BBB opening has been shown to activate the innate immune system in animal models of Alzheimer's disease. Amyloid plaque clearance and promotion of neurogenesis in these studies suggest that MRgFUS-mediated BBB opening may be a new paradigm for neurodegenerative disease treatment in the future. Here, we review the current status of preclinical and clinical trials of MRgFUS-mediated thermal ablation and BBB opening, described their mechanisms of action, and discuss future prospects.

Micro-Processing of Glass Substrates Using a Laser (레이저를 이용한 유리기판의 미세가공(微細加工))

  • Lee, Cheon;Toyoda, Koichi
    • Proceedings of the KIEE Conference
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    • 1994.07b
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    • pp.1425-1427
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    • 1994
  • Laser ablation of glass substrates (8K-7 and synthetic quartz) using a transversely excited atmospheric (TEA) $CO_2$ laser has been inverstigated to obtain high speed etching. The ablation occurs by local heating of a substrate with a focused TEA-$CO_2$ laser beam. The dependence of ablation rate on pulse count and repetition-rate of laser has been discussed.

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