• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.6
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• pp.987-994
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• 2000

Aspergillus coreanus NR 15-1, Asp. oryzae NR 15-3 and Asp. oryzae NR 2-5 isolated from traditional Korean nuruk were screened as parental strains producing starch hydrolyzing enzymes. They were mutagenized by N-methyl -N'-nitro-N-nitrosoguanidine (NTG) and mutants were isolated for analysis of various amylase activities and the ability of acid production. Among them, the mutants harboring high saccharogenic activity, dextrinogenic activity, and the ability of acid production were selected. Fifteen, six, and five strains of mutants were isolated from Asp. coreanus NR 15-1, Asp. oryzae NR 2-5, and Asp. oryzae NR 15-3, respectively followed by NTG mutagenesis. Among these mutants, thirteen strains were identified as auxotrophic mutants. \ulcorner (Arg.￣) mutant from Asp. coreanus NR 15-1 showed high glucoamylase activity and total acid productivity. Z6 (Ade.￣) mutant from Asp. oryzae NR 2-5 showed the highest $\alpha$-amylase activity, therefore \ulcorner and Z6 mutant were selected.

• Journal of Preventive Medicine and Public Health
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• v.9 no.1
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• pp.77-86
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• 1976

This study was attempted to know that the interactions of various fungi, and methionine and $MgSO_4$ introduced as the substrate of culture media for fungi were affected to produce aflatoxins by Asp. flavus. 5 different fungi were isolated from the fermented soybean mash and were cultured in Chemically Defined medium (C. D. media) and soybean mash at $25^{\circ}C$ for 10 days. (1) It was confirmed that Asp. flavus produced aflatoxins in the C. D. medium and soybean mast, but that Asp. niger, Asp. oryzae, Asp. awamori and Asp. terreus did not produced them respectively. (2) Asp. flavus cultured with Asp. niger did not produce aflatoxins in C. D. medium, but produced in soybean mash, in other hand, Asp. flavus with other fungi except Asp. niger produced aflatoxins in C. D. medium and soybean mash. (3) The growth of fungi were more prosperous in the seperate culture than in the mixed culture. (4) In the C. D. medium added 20% of cultured medium of Asp. niger, Asp. flavus did not produce aflatoxins but other cultured medium did not prohibit the production of aflatoxins by Asp. flavus. (5) On the contrary, $MgSO_4$ increasing the productivity of aflatoxins by Asp. flavus in the C. D. medium, methionine known as one of precursor of aflatoxins did not affected the increasing productivity with significance.

• Proceedings of the CALSEC Conference
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• 2000.08a
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• pp.255-263
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• 2000

네트워크를 통해 어플리케이션을 임대해주는 정보시스템 서비스 모델인 ASP 모델이 IT 시장에서 새로운 비즈니스 모델로 등장하였다. 그러나 ASP 모델은 기존의 정보시스템 모델에 비해 특정 서비스에 많은 서비스제공자가 임시적으로 결합되고, 정보자산이 공중망과 데이터센터에 위치하는 특징을 가지고 있다. 그러므로 ASP 서비스를 성공적인 수행하기 위해서는 ASP 사업자가 서비스의 제공능력이 있는지에 대한 인증활동과 ASP 서비스 도입 및 운영과정이 적절하게 이루어지고 있는가에 대한 감리활동이 요구된다. 따라서 본 연구는 ASP의 특징을 분석하고, ASP 인증ㆍ감리 프레임워크를 설계를 수행하고자 한다. 이를 위해, 기존연구를 바탕으로, 분류기준을 기술적 계층, 수명주기, 공급자/고객의 관점이라는 세 가지 차원에서 정의하며, 각각의 세부항목 및 내용을 정의하고자 한다.

• Asia pacific journal of information systems
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• v.14 no.1
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• pp.43-58
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• 2004

Recently, a market size for IT outsourcing has grown. As internet technology has been developed for accessing information resources, information systems have become internet-based, which is called an ASP(Application Service Provider); evaluating the performance for ASP becomes important. Therefore, this paper attempts to investigate the salient characteristics of ASP. An ASP success model is proposed based on information systems success models found in the literature. Our model is tested through a survey from 291 small companies. LISREL is used to demonstrate the suitability of our model, and the success factors for ASP are also investigated. Our result is likely to help provide useful guidelines for the successful ASP implementations.

• IE interfaces
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• v.19 no.1
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• pp.62-69
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• 2006

In these days companies are rapidly implementing the extended enterprise collaboration to provide enhanced management services and products based on the enterprise integration that human resources, technologies and the management process. In this corporate environment, ASP (Application Service Provider) which is the developed type of outsourcing in the area of information technology, is a good alternative for corporate information system management. ASP defines as a software leasing service which is supplied through networks instead of purchasing application software with high price. For successful implementation of ASP, it is necessary to develop the certification methodology to ensure safety and reliability of ASP. The paper provides the safe and reliable certification methodology for ASP. In order to develop it, the critical issues related to service quality and certification of ASP are identified and the systematic certification methodology of application and service provider(service environment) domains of ASP are provided. A evaluation method for the developed certification methodology is also proposed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.10
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• pp.3011-3022
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• 2009

The analytic test results are as follows. This thesis categorized into independent variables, multiple factors, such as asset attributes, cost reduction expectation, corporate IT competence, service qualities, system adequacy, information security, easy system management, uncertain IT, supplier capacity, intra-industry competition. And, this research thesis categorized into moderators, the factor, such as the adequacy between suppliers and customers industries. And, this categorized into dependent variables, multiple factors, such as the effects of ASP introduction. But, it was analyzed that only cost reduction expectation out of independent variables had not positive effects on the effects of ASP introduction. And, it was confirmed that the higher communications between suppliers and customers' industries, and the higher fulfillment of contracts, suppliers' service qualities, and suppliers' cooperation with customers had the adjusting effects on factors of ASP-based introduction.

• Proceedings of the Korea Society for Industrial Systems Conference
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• 2008.10b
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• pp.365-384
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• 2008

Many studies on ASP outsourcing area have focused on the Critical Success Factors(CSFs) of ASP outsourcing projects or on the service quality of ASP Service. But these studies have limitations to explain how to succeed in doing ASP outsourcing project. The objective of this research is to overcome this limitation by using the concept of "IT Risk" in Outsourcing. The effective control of the risks-caused during the IS outsourcing process-gives (ASP service using) users a powerful tool to minimize the risks and thus maximizes the possibility of ASP outsourcing project success. In order to perform this objective, this research set up the research model which is composed of three concepts. The three concepts are 1. Undesirable Outcomes(:UO) as IT outsourcing Risks, 2. The Source of Risks(:SOR) influencing the UO, and 3. the intention to get/execute Real Option Portfolio to control the risk level of SORs and UOs. This research has some important and interesting implications on the ASP outsourcing area. First, this research classifies the risk factors as three concepts and finds the interactions among them. Second, Using Real Option portfolio can control the risks effectively occurred during outsourcing projects. Third, Vendors(ASP service providers) can offer users IN TIME the options which can minimize the occurrence of risks.

• Journal of Information Technology Applications and Management
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• v.13 no.1
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• pp.17-38
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• 2006

Recently, ASP business models based on Web services are attracting considerable attention and regarded as the next generation of the ASP business models. It is, however, undesirable for ASP users to adopt them simply because the Web services are the new trend in the IT world. Instead, an in-depth comparison of the benefits against the costs between the Web services based ASP business models and the traditional models are required. Furthermore, it is desirable that this comparative analysis should be applied from the ASP users' viewpoints rather than those of the government or ASP providers. So, we have applied a comparative ROI (Return on Investment) analysis from the ASP users' perspective and shown that the Web services based ASP business models (382%) are superior to the traditional models (280%) in terms of ROI. We have also employed Balanced Scorecard (BSC) framework to keep the balance between tangible and intangible benefits considering the characteristics of IT value measurement.

• Bulletin of the Korean Chemical Society
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• v.24 no.6
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• pp.817-823
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• 2003

We have performed ab initio calculation on the active site of HIV-1 protease. The FEP method was used to determine the binding free energy of four different of protonated states of HIV-1 protease with inhibitor. The structure of the active site and hole structure was taken from the X-ray crystallographic coordinates of the C₂ symmetric inhibitor A74704 protease bound. The active site was modeled with the fragment molecules of binding pocket, acetic acid/ acetate anion (Asp25, Asp125), formamide (amide bond of Thr26/Gly27, Thr126/ Gly127), and methanol as inhibitor fragment. All possibly protonated states of the active site were considered, which were diprotonated state (0, 0), monoprotonated (-1, 0),(0, -1) and diunprotonated state (-1, -1). Once the binding energy Debind, of each model was calculated, more probabilistic protonated states can be proposed from binding energy. From ab-initio results, the FEP simulations were performed for the three following mutations: Ⅰ) Asp25 … Asp125 → AspH25 … Asp125, ⅱ) Asp25 … Asp125 → Asp25 … AspH125, ⅲ) AspH25 … Asp125 → AspH25 … AspH125. The free energy difference between the four states gives the information of the more realistic protonated state of active site aspartic acid. These results provide a theoretical prediction of the protonation state of the catalytic aspartic residues for A74707 complex, and may be useful for the evaluation of potential therapeutic targets.

• The KIPS Transactions:PartD
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• v.11D no.5
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• pp.1063-1072
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• 2004

In the ASP(Application Service Provider) business, applications using database sometimes require some data from clients' databases. These days such data are extracted from client database using manual database operations as an EXCEL file and the ASP, once receiving this file, transfers it into the application's database using manual database operations. This paper describes how to deal with data transmitting between the client database and ASP database on the web without using database manual operations for data extraction and insertion. We propose a framework which enables to transmit client data in a systematical way, to match different attribute names of each database for sharing same attribute values, and to avoid exposing information about the network path of client database to the ASP. This approach consists of two steps of data processing. The first is extracting data from client database as XML format by using a downloaded client program from ASP site, the second is uploading and storing the XML file into the ASP database. The implemented prototype system shows the suggested data integration paradigm is valid and ASP business needing integration of client database can be activated using it.