• Journal of Veterinary Science
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• 제24권2호
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• pp.21.1-21.5
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• 2023

Under the current African swine fever (ASF) epidemic situation, a science-based ASF-control strategy is required. An ASF transmission mechanistic model can be used to understand the disease transmission dynamics among susceptible epidemiological units and evaluate the effectiveness of an ASF-control strategy by simulating disease spread results with different control options. The force of infection, which is the probability that a susceptible epidemiological unit becomes infected, could be estimated by applying an ASF transmission mechanistic model. The government needs to plan an ASF-control strategy based on an ASF transmission mechanistic model.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2010년도 추계학술대회
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• pp.4-6
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• 2010

지상파 항법인 로란은 전송된 신호는 장파특성에 따라 지표파에 의한 정보를 전달하게 되는데 지표면과 해수면의 특성 즉, 전도도에 따라 전파의 지연시간이 달라진다. 이것은 정확도를 저하시키는 원인이 된다. 그러므로 보다 정확도가 요구되는 지역에서는 전파지연에 의해 발생하는 시간적 공간전 변화(ASF)를 보상하게 되면 정확도를 향상시킬 수 있다. 로란시스템의 현대화와 eLoran 시스템에서는 ASF를 보상함으로써 선박이 항만으로 진입 및 접안할 때 활용할 수 있는 정확도 기준을 마련하고 있다. 이 조건을 충족시키기 위해서는 ASF의 정밀측정 필수이며, 본 논문에서는 포항송신국 근해인 영일만 해상에서 ASF를 실측한 결과와 그에 필요한 측정기술을 보고한다.

• Journal of information and communication convergence engineering
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• 제5권4호
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• pp.295-299
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• 2007

This paper presents the ASF(Additional Secondary Factor) modeling of DGPS beacon signal. In addition to DGPS's original purpose, the feasibility to utilize DGPS system for timing and navigation has been studied. For timing and navigation, the positioning system must know the accurate time delay of signal traveling from the transmitter to receiver. Then the delay can be used to compute the user position. The DGPS beacon signal transmits the data using medium frequency, which travels through the surface and cause the additional delay rather than the speed of light according to conductivities and elevations of the irregular terrain. We introduce the modeling of additional delay(ASF) and present the results of implementation. The similar approach is Locan-C. Loran-C has been widely used as the maritime location system and was enhanced to E-Loran(Enhanced Loran). E-Loran system uses the ASF estimation method and is able to provide the more precise location service. However there was rarely research on this area in Korea. Hence, we introduce the ASF and its estimation model. With the comparison of the same condition and data from the original Monteath model and ASF estimation data of Loran system respectively, we guarantee that the implementation is absolutely perfect. For further works, we're going to apply the ASF estimation model to Korean DGPS beacon system with the Korean terrain data.

• Archives of Plastic Surgery
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• 제46권1호
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• pp.75-78
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• 2019

It is difficult to differentiate acute skin failure (ASF) from pressure ulcer (PU). ASF is defined as unavoidable injury resulting from hypoperfusion caused by severe dysfunction of another organ system. We describe a case of ASF mistaken as PU that resulted in a legal dispute. A 74-year-old male patient was admitted to our intensive care unit with sepsis due to bacterial pneumonia. Despite the use of air cushions and regular position changes, skin ulcerations occurred over his occiput, back, buttock, elbow, and ankle. After improvement in his general condition, he was transferred to the department of plastic and reconstructive surgery. Debridement was performed immediately, followed by conservative treatment (including a vacuum-assisted closure device) for 6 weeks. The buttock and occiput wounds were treated surgically. Despite complete healing, his caregivers sued the hospital for failing to prevent PU formation. ASF is a pressure-related injury resulting from hemodynamic instability due to organ system failure. Unlike PU, ASF may occur despite the implementation of all appropriate preventive measures. Furthermore, misdiagnosis of ASF as PU can lead to litigation. Therefore, it is critical for the proper diagnosis to be made quickly, and for physicians to explain that ASF occurs despite proper preventative treatment.

• BMB Reports
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• 제48권12호
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• pp.685-690
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• 2015

The eukaryotic genome is packed into chromatin, which is important for the genomic integrity and gene regulation. Chromatin structures are maintained through assembly and disassembly of nucleosomes catalyzed by histone chaperones. Asf1 (anti-silencing function 1) is a highly conserved histone chaperone that mediates histone transfer on/off DNA and promotes histone H3 lysine 56 acetylation at globular core domain of histone H3. To elucidate the role of Asf1 in the modulation of chromatin structure, we screened and identified small molecules that inhibit Asf1 and H3K56 acetylation without affecting other histone modifications. These pyrimidine-2,4,6-trione derivative molecules inhibited the nucleosome assembly mediated by Asf1 in vitro, and reduced the H3K56 acetylation in HeLa cells. Furthermore, production of HSV viral particles was reduced by these compounds. As Asf1 is implicated in genome integrity, cell proliferation, and cancer, current Asf1 inhibitor molecules may offer an opportunity for the therapeutic development for treatment of diseases.

• 한국자동차공학회논문집
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• 제16권1호
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• pp.175-180
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• 2008

Due to the global environment problems and the consumer's need for higher vehicle performance, it becomes very important for the global car makers to reduce vehicle weight. To reduce vehicle weight, many car makers have tried to use lightweight materials, for example, aluminum, magnesium, and plastics, for the vehicle structures and components. Especially, the ASF(aluminum space frame) is known for the excellent concept of the vehicle to satisfy structural rigidity, safety performance and weight reduction. In this research, the design of experiments and the multi-disciplinary optimization technique were utilized to meet the weight and structural rigidity target of the ASF. For the structural performance of the ASF, the locations and the size of aluminum extruded frames, aluminum cast nodes, and the aluminum sheets were optimized. As a result, the optimization design procedure has been set up to meet both structural and weight target of the ASF, and the assembled ASF showed good structural performance and weight reduction.

• 한국의류학회지
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• 제28권9_10호
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• pp.1208-1218
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• 2004

The purposes of this study were to examine the alliance success factors (ASF) and the business environments (BE) from the textile companies' viewpoint, to examine the differences in ASF and BE by firm characteristics, and to examine the relationships between BE and ASF. BE included the degree of market competition and the firm's competitive advantage, and firm characteristics included type of business, the number of employees, and length of business operation. Data were obtained from 155 textile companies in Daegu and Gyeongbuk regions in Korea via a questionnaire survey. Four factors including relationship capital, organizational support, alliance management, and alliance performance were extracted from ASF, and resources, product development, and marketing were extracted from the firm's competitive advantage. There were differences in product development by the number of employees and in the degree of market competition by type of business. The degree of market competition had significant relationships with all of ASF while the firm's competitive advantage differed in the relationships.

• Journal of Veterinary Science
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• 제22권2호
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• pp.26.1-26.6
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• 2021

Fourteen African swine fever (ASF) outbreaks occurred in the pig farms in the northwestern region of South Korea, near the border with North Korea, from September 16, 2019 to October 9, 2019. Active and passive surveillance on the ASF-infected farms indicated that the infection was limited only to pigsties where the infected pigs were detected on the farm for the first time before further transmission to other pigsties and farms. This early detection could be one of the pivotal factors for the prompt eradication of ASF in domestic pig farms within 1 month in the northwestern region of South Korea.

• 대한한방내과학회지
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• 제43권4호
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• pp.529-541
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• 2022

Objectives: Acanthopanax senticosus is a tree used in traditional medicine for various diseases. In this study, we investigated the anti-cancer effects of a water extract of Acanthopanax senticocus fruit (ASF) on 2 human breast cancer cell lines (MCF-7 and MDA-MB-231). Methods: The MTT assay was used to assess cell proliferation. The expression of apoptosis-related genes was assessed by quantitative real-time PCR. Results: ASF treatment caused a dose-dependent inhibition of cell growth in both estrogen-independent MDA-MB-231 and estrogen-dependent MCF-7 breast cancer cells. ASF decreased mRNA expression of the apoptotic suppressor gene Bcl-xL, and increased mRNA expression of proapoptotic genes. ASF increased the mRNA expression of p21 and RIP-1 in both cell types. ASF decreased the mRNA expression of survivin in the MCF-7 cell line. Conclusions: ASF exhibits anti-cancer activity involving apoptotic cell death.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2010년도 춘계학술대회
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• pp.370-371
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• 2010

Loran(LOang RAnge Navigation) 신호에 의한 항법은 GPS(Global Positioning System) 활성화 전까지 주요한 항법시스템으로 이용되어 왔다. 특히 선박들 항행하는데 있어서 필수적인 기능을 담당하였다. 그러나 산업의 발전과 더불어 항행 외에 항만 근접과 육상에서의 항법 그리고 정밀시각활용과 같은 분야에서는 지금의 항법정확도 보다 우수한 정확도가 필요하다. 그 정확도를 향상시킬 수 있는 방법은 Loran 송신국과 사용자 위치 사이의 전파지연 즉, ASF (Additional Secondary Factor)를 정확히 측정하는 것이다. 본 연구에서는 우리나라에서 방송하는 9930M(포항)과 같이 TOC(Time of Coincidence) 테이블이 없는 방송시스템에서 절대시간 지연을 측정할 수 있는 기법을 개발하였으며, 송신국으로부터 몇 개의 측정지정에서 ASF를 측정한 결과를 제시한다.