• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.5
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• pp.270-276
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• 2017

The aim of this study was to investigate the effects of the water extract of Albizziae Cortex (AC) on the learning and memory impairments. AC was administered to normal mouse and scopolamine-injected amnesia mouse model. Passive avoidance test, Y-maze test, and Morris water maze test were conducted to confirm the cognitive-enhancing activities of AC. Acetylcholinesterase (AChE) activity and acetylcholine (Ach) content were measured after oral administration of AC. On the passive avoidance test, AC (200 mg/kg) significantly increased latency time and recovered scopolamine-impaired learning and memory in mice. In addition, AC (200 mg/kg) reduced Exploration time in target quadrant and reversed the scopolamine-induced cognitive impairments in the Y-maze test. Moreover, AC (200 mg/kg) increased exploration time in target quadrant and improved scopolamine-reduced escape latencies in the Morris water maze test. These effects were presented by regulatory effects of AC on AChE activity and Ach content. Taken together, AC increases cognitive-enhancing activities and ameliorates scopolamine-induced learning and memory impairment. AC might be a potential agent for prevention and treatment of amnesia and dementia.

• Journal of Power Electronics
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• v.19 no.1
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• pp.24-33
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• 2019

A new modeling method for AC-AC switched capacitor converters (SCCs) is introduced in this study. The proposed analytical method aims to accurately describe the input-output characteristics of AC-AC SCCs and establish a mathematical model for static voltage conversion ratio and equivalent resistance, which are key performance metrics for SCCs. A quantitative analysis of converter regulation capability is addressed on the basis of the modeling method. In this analysis, the effects of the control parameters and individual components on SCCs are illustrated extensively. Component stresses, such as the peak value and transient variation of the voltage/current of the converter, are also presented. The effectiveness of the proposed method is verified by comparing it with the existing modeling method and applying it to an AC-AC SCC with a conversion ratio of three. Two 1 kW prototypes are built in a laboratory, and their experimental results exhibit good agreement with the theoretical analysis.

• Biomolecules & Therapeutics
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• v.31 no.6
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• pp.611-618
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• 2023

Rhizome of Alisma orientale has been used as a traditional medicine for treating kidney diseases in East Asian countries. Its inhibitory effects on hypersensitivity responses have been reported for methanol extracts, with alisol B 23-acetate (AB23Ac) being the most active constituent among six terpenes in inhibiting the direct passive Arthus reaction. However, whether AB23Ac has efficacy against allergic asthma has not been tested to date. The in vivo efficacy of AB23Ac in an ovalbumin (OVA)-induced allergic asthma mouse model was evaluated by administrating AB23Ac before OVA sensitization or OVA challenge in BALB/c mice. AB23Ac suppressed antigen-induced degranulation of RBL-2H3 mast cells in a concentration-dependent manner. The administration of AB23Ac both before OVA sensitization and OVA challenge greatly lowered pulmonary resistance and the increase in immune cell counts and inflammatory responses around the peribronchial and perivascular regions. In addition, the inflammatory cytokine levels of Th1/Th2/Th17 cells in the bronchoalveolar lavage fluid decreased in the AB23Ac-treated groups. AB23Ac reduced the number of PAS-stained cells in the lungs. Furthermore, a computer modeling study indicated that AB23Ac can bind tightly to spleen tyrosine kinase (Syk). These results suggest that AB23Ac may ameliorate allergic asthma by suppressing immune responses in dendritic cells during sensitization and in mast cells during challenge periods.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.41 no.6
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• pp.91-98
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• 2004

This paper proposes a PCB plane model for generic SPICE circuit simulators. The proposed model reflects two frequency-dependent losses, namely skin and dielectric losses. After power/ground plane pair is divided into arrays of unit-cells, each unit-cell is modeled using a transmission line and two loss models. The loss model is composed of a resistor for DC loss, series HL ladder circuit for skin loss and series RC ladder circuit for dielectric loss. To verify the validity of the proposed model, it is compared with SPICE ac analysis using frequency-dependent resistors. Also, we show that the estimation results using the proposed model have a good correlation with that of VNA measurement for the typical PCB stack-up structure of general desktop PCs. With the proposed model, not only ac analysis but also transient analysis can be easily done for circuits including various non-linear/linear devices since the model consists of passive elements onl.

• Proceedings of the KIPE Conference
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• 1996.06a
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• pp.89-92
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• 1996

This paper describes a detailed simulation model of the static condenser (STATCON) to analyze the dynamic interaction with the ac transmission line. The static condenser was represented by a 12-pulse voltage-source inverter sharing an energy storage dc capacitor. The voltage-source inverter consists of two 6-pulse bridges modeled with ideal gate-turn-off switches. The control system for the static condenser was designed through a mathematical model deduced from the equivalent circuit. Simulation results show that the conceived model is very effective to analyze the dynamic interaction between the static condenser and the ac transmission system.

• Journal of Korean Society of Environmental Engineers
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• v.32 no.10
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• pp.936-941
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• 2010

This study was conducted to investigate formaldehyde removals by silver nano-particles attached on the surface of granular activated carbon (Ag-AC) and to compare the results to those obtained with ordinary activated carbon (AC). The BET analysis showed that the overall surface area and the fraction of micropores (less than $20{\AA}$ diameter) of the Ag-AC were significantly decreased because the silver particles blocked the small pores on the surface of the Ag-AC. The formaldehyde removal capacity of the Ag-AC determined using the Freundlich isotherm was higher than that of AC. Despite the decreased BET surface area and micropore volume, the Ag-AC had the increased removal capacity for formaldehyde, presumably due to catalytic oxidation by silver nano-particles. In contrast, the adsorption intensity of the Ag-AC, estimated by 1/n in the Freundlich isotherm equation, was similar to that of the ordinary AC, indicating that the surface modification using silver nano-particles did not affect the adsorption characteristics of AC. In a column experiment, the Ag-AC also showed a longer breakthrough time than that of the AC. Simulation results using the homogeneous surface diffusion model (HSDM) were well fitted to the breakthrough curve of formaldehyde for the ordinary AC, but the predictions showed substantial deviations from the experimental data for the Ag-AC. The discrepancy was due to the catalytic oxidation of silver nano-particles that was not incorporated in the HSDM. Consequently, a new numerical model that takes the catalytic oxidation into accounts needs to be developed to predict the combined oxidation and adsorption process more accurately.

• Proceedings of the KIEE Conference
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• 2003.10a
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• pp.174-177
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• 2003

본 논문에서는 AC PDP의 유지방전구간에서의 인가전압에 따른 방전전류, 공간전압, 벽전하 등의 변화를 새로운 AC PDP를 위한 등가회로모델을 사용하여 효율적이고 간편하게 시뮬레이션 한 결과를 소개한다. 벽전하의 정확한 분석은 안정적이고 효율적인 AC PDP의 구동 방법을 개발하기 위해 계속 연구, 보고 되어 왔지만, 인가되는 전압의 변화에 따른 시간적인 셀 내부의 변화를 빠르고 편리하게 분석하고 이해하는데 효과적인 방법은 제시되지 못하였다. 본 논문에서는 AC PDP의 전극간 물리적인 특성을 고려하여 3개의 직렬 커패시터와 1개의 병렬 커패시터, 2개의 싸이리스터를 사용하여 AC PDP를 위한 등가회로모델을 구성하여 제시하였다. 제안된 등가회로모델은 SPICE와 같은 표준 회로시뮬레이션 툴에 손쉽게 적용가능하며, 이러한 방법으로 분석된 패널내의 전류, 공간전압, 벽전하의 동특성을 소개하였다. 등가회로모델을 이용한 시뮬레이션 결과는 실험을 통한 측정 결과와 비교하여 그 정확성을 검증하였다. 인가전압의 시간적 변화의 따른 유입전류 및 셀 내의 전압 및 전하의 분포를 손쉽고 정확하게 시뮬레이션 할 수 있는 본 AC PDP의 등가회로모델은 AC PDP의 특성을 이해하는 데에 중요한 도구가 될 것이며 효율적인 구동 방식의 개발 및 분석 등에 널리 활용될 수 있을 것이다.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.14 no.6
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• pp.15-24
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• 2004

Electronic commerce is widely used with the development of information communication technologies in internet using public key certificates. And the study for access control in Web application and DB system is also progressed actively. There are many verification method for PKC(Public Key Certificates), which are CRL, OCSP, SCVP and others. But their certificates verification methods for PKC cannot to be applied to PMI(Privilege Management Infrastructure) which is using AC(Attribute certificates) because of synchronization of PKC and AC. It is because AC has no public key, AC Verifier must get the PKC and verify the validity on PKC and AC. So in this paper we proposed the new AC-based certificate verification model. which provide the synchronization in two certificates(AC and PKC).

• Proceedings of the KIPE Conference
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• 1998.10a
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• pp.928-933
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• 1998

This paper presents a novel current control system to eliminate the steady state control error and to improve the transient characteristics for PWM AC-DC converter. A general mathematical model of the converter that is represented as a state-space model is first established. The state-space model is used for the simulation of PWM switching converter with the proposed current control system. The proposed sinusoidal tracking control system that does not require coordinate transformations using principle of the integral controller is described. It is proved that the steady state deviation reduces to zero through a transfer function of source current control system. Finally, it is seen that simulations agree with the experimental results in source current and reference of controlled ac current loop.

• KIEE International Transactions on Power Engineering
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• v.4A no.3
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• pp.115-121
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• 2004

This paper presents the model for an AC electric railway system using the PSCAD/EMTDC program. It is composed of a scott-transformer, an auto-transformer, catenary and electric trains, etc. After obtaining the models of the fundamental elements describing the AC electric railway system and its behavior, we have analyzed and tested an actual AC electric railway system focused on the amplification of harmonic current to verify the proposed model. The simulation results from the proposed approach and the measurement data from the test are described.