• Journal of Bio-Environment Control
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• v.29 no.2
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• pp.153-160
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• 2020

This study was conducted out to investigate the effect of harvest time of the day, precooling or not, and temperature of precooling and storage on the marketability in strawberries 'Maehyang' for export in May. Strawberry colored with 60±5% of the skin was harvested at 07:00 am or 15:00 pm, respectively. After harvesting, some strawberries were precooled to 0, 2, 4℃ for 3 hours in the cold store, respectively, and the others were kept at room temperature. And then, strawberries were stored at low temperature in the cold store set at 4, 8 or 10℃ storage temperatures. The weight loss rate, firmness, soluble solids content, color, incidence of gray mold of strawberries were measured at two days intervals during storage for 14 days. Both 07:00 am and 15:00 pm harvest, fruits as the storage periods lapses increased weight loss rate compared to the weight at harvest time of the day, and the difference in the weight loss rate of fruits depending on the treatment was greater at 15:00 pm harvest than at 07:00 am. Firmness tended to increase again after 8th day at 07:00 am or 15:00 pm harvest, respectively. In the afternoon harvest, 10℃ storage without precooling showed the lowest fruit firmness on the 2nd day after storage. The soluble solids content at 07:00 am or 15:00 pm harvest tended to be maintained at high value with precooled and stored at low temperature as storage days elapse. The color values were significantly higher at 'L' indicating brightness and lower at 'a', indicating redness at low storage temperature regardless of harvesting time of the day and whether it was precooling or not. The incidence of gray mold was higher at 15:00 pm harvest than at 07:00 am harvest, and it was significantly higher in the treatments stored at 10℃ after precooling similarly. In this study, strawberry 'Maehyang' for export harvested at 07:00 am and stored at 4℃ after precooling at 0℃ maintained the best shelf life, therefore, it is judged that desirable to harvest in the morning with low temperature and to precool and store at low temperature.

• The Korean Journal of Malacology
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• v.20 no.2
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• pp.111-120
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• 2004

We investigated the reproductive cycle of Corbicula japonica with its gonadal development by histological observations, and the seasonal changes in biochemical mass and foot muscle of the adductor muscle, visceral mass and foot muscle of the clam by biochemical analysis, from January to December, 2003. The reproductive cycle of this species can be classified into five successive stages: early active stage (February to April), late active stage (April to July), ripe stage (June to August), partially spawned stage (July to September) and spent/inactive stage (September to March). According to ANOVA test, there were significant differences (p < 0.05) in total protein, total lipid and glycogen contents among months for all of the visceral mass, adductor muscle and foot muscle. Total protein content was highest in adductor muscle, while lowest in visceral mass. There was no correlation in total protein content between visceral mass and adductor muscle (p = 0.208). However, strong positive correlation was found between adductor muscle and foot muscle (r = 0.769, p < 0.001). In visceral mass, total lipid content was the highest; it was 2 or 3-fold higher than in adductor muscle or foot muscle. The monthly change was also most dynamic in visceral mass. It decreased from January to March (early active stage), and reached maximum in April (late active stage). From May to August (ripe and partially spawned stage), it dradually decreased and then increased again until October (spent/inactive stage). Multiple comparisons showed that total lipid content in visceral mass between all of the adjacent two months was significaltly different (p < 0.05). There were strong negative correlations in total lipid content between visceral mass and adductor muscle (r = 0.687, p < 0.001), and between visceral mass and foot muscle (r = 0.473, p = 0.008). Changes of glycogen content were more or less similar to the changes of lipid contents in visceral mass, adductor muscle and foot muscle, except for April. In April, glycogen content in visceral mass was over four times higher than that in adductor muscle or foot muscle. There was a positive correlation in glycogen content between adductor muscle and foot muscle (r = 0.686, p < 0.001). Especially, total lipid content showed a negative correlation between the adductor muscle and visceral mass. Therefore, these results indicate that the nutrient content of the adductor muscle, visceral muscle and foot muscle changed in response to gonadal energy needs.

• Journal of Ginseng Research
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• v.31 no.4
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• pp.181-190
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• 2007

Compound K (CK), a protopanaxadiol ginsenoside metabolite, was previously shown to have immunomodulatory effects. In this study, we isolated the CK rich fractions (CKRF) from Korean Red Ginseng and investigated the regulation of CKRF-mediated inflammatory signaling during Toll-like receptor (TLR)-mediated cellular activation. Among various TLR ligands, CKRF considerably abrogated TLR4- or TLR9-induced inflammatory signaling. Both LPS and CpG-containing oligodeoxynucleotides (CpG-ODN) stimulation rapidly activates mitogen-activated protein kinases [MAPKs; extracellular signal-regulated kinases 1/2 and p38], NF-${\kappa}B$, and expression of pro-inflammatory cytokines tumor necrosis factor-${\alpha}$, and interleukin-6 in murine bone marrow-derived macrophages (BMDMs) in a time- and dose-dependent manner. Of interest, pre-treatment of CKRF in either LPS/TLR4- or CpG-ODN/TLR9-stimulated macrophages substantially attenuated the LPS-induced inflammatory cytokine production and mRNA expressions, as well as MAPK and NF-${\kappa}B$ activation. To our knowledge, this is the first description of the inhibitory roles for CKRF in TLR4- or TLR9-associated signaling in BMDMs. Collectively, these results demonstrate that CKRF specifically modulates distinct TLR4 and TLR9-mediated inflammatory responses, and further studies are urgently needed for their in vivo roles for potential therapeutic uses, such as in systemic inflammatory syndromes.

• Journal of Ginseng Research
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• v.31 no.4
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• pp.196-202
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• 2007

Skin wrinkles are associated with collagen synthesis and matrix metalloproteinase-I (MMP-1) activity. This study was carried out to select optimum ratio of 3 herbs in skin health food for anti-wrinkle. Human dermal fibroblast cell was incubated with experimental samples, which were Korean red ginseng ethanol extracts (ER), Torilis fructus water extracts (WT), Corni fructus water extracts (WC) and their mixtures (WM1, WM3). And then we determined effects on collagen biosynthesis, MMP-1 activity and SOD activity in human dermal fibroblast cell. In control group, collagen biosynthesis was amounted at 474.8 ng/ml and 533.9 ng/ml, 539.3 ng/ml, 514.1 ng/ml in ER, WT and WC respectively. Furthermore, WM3 (KTNG0345) was increased to 561.45 ng/ml. MMP-1 activity of ER, WT, WC, WM1 were determined to 31.9 ng/ml, 32.85 ng/ml, 32.0 ng/ml, 31.3 ng/ml and WM3 (KTNG0345) was decreased to 28.85 ng/ml. In addition, the experimental samples showed a antioxidative activities. From this results, we conclude that Korean red ginseng ethanol extracts, Torilis fructus water extracts, Corni fructus water extracts and their mixtures have a anti-wrinkle effect and WM3 (KTNG0345) may be regarded as an optimum composition for synergic effect producing. The standardized components of KTNG0345, ginsenoside-$Rb_1$, torilin and loganin were identified at 10.85 mg/g, 0.128 mg/g and 3.92 mg/g respectively.

• Clinical and Experimental Reproductive Medicine
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• v.37 no.1
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• pp.65-72
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• 2010

Objective: To compare the respective pregnancy outcomes of cycles undergoing elective two cleavage-stage embryos transfer (2ET) and three cleavage-stage embryos transfer (3ET) in fresh in vitro fertilization and embryo transfer (IVF-ET) program. Methods: We conducted a retrospective matched case control study that included 100 women with 2ET and 100 women with 3ET from January 2007 to June 2009. Subjects were matched for reproductive profiles and cycle characteristics. All of transferred embryos in both groups had good qualities. Pregnancy rates (PR), implantation rate, and multiple PR were compared. Results: Demographics, stimulation parameters and embryological data were comparable in both groups. Main pregnancy outcomes with 2ET and 3ET groups were not statistically different; implantation rate (41.0% vs. 35.3%), positive pregnancy rate (58.0% vs. 60.0%), clinical PR (55.0% vs. 59.0%), ongoing PR (51.0% vs. 55.0%), respectively. However, the 3ET group showed significantly higher multiple pregnancy and triplet pregnancy rates (30.9% vs. 50.8%, p=0.031; 1.8% vs. 11.9%, p=0.036, respectively). Conclusion: In women with favorable conditions and good quality embryos undergoing IVF, 2ET can get pregnancy outcomes comparable to those of 3ET and reduce multiple pregnancy (especially, triplet pregnancy).

• Korean Journal of Ichthyology
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• v.21 no.1
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• pp.1-6
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• 2009

The effect of water temperature on fasting and post-prandial total ammonia excretion (TAN) of the starry flounder Platichthys stellatus (mean body weigh : $42.4{\pm}3.4g$) was studied. The fasting and post-prandial TAN excretions were measured under three different water temperatures (10, 15 and $20^{\circ}C$) for 24 hours using a recirculating system. In each treatment three replicates were set up and total 45 fish were used. Fish were taken to the indoor aquarium, acclimated over 10 days at three temperatures, and transferred to TAN measuring system for measurements of TAN excretion at the same temperatures. After 3 days of starvation, fasting TAN excretion was measured at each temperature. To investigate post-prandial TAN excretion, fish were hand-fed to satiation level with a commercial diet containing 50.2% crude protein for 7 days, two times daily 08 : 00 and 16 : 00 h. The fasting and postprandial TAN excretion increased with increased water temperature (p<0.05). Mean fasting TAN excretion rates at 10, 15 and $20^{\circ}C$ were 10.9, 11.2 and $12.2mg\;TAN\;kg\;fish^{-1}\;h^{-1}$, respectively. The value at $20^{\circ}C$ was higher than those at 10 and $15^{\circ}C$ (p<0.05), but there was no significant difference between $10^{\circ}C$ and $15^{\circ}C$. Mean post-prandial TAN excretion rates at 10, 15 and $20^{\circ}C$ were 33.0, 43.4 and $55.3mg\;TAN\;kg\;fish^{-1}\;h^{-1}$, respectively. Two peaks of post-prandial TAN excretions were observed, and the second peak was always greater than the first. The post-prandial TAN excretion rate reached to the maximum after 10 hours from the first feeding at $10^{\circ}C$($45.3mg\;TAN\;kg\;fish^{-1}\;h^{-1}$), $15^{\circ}C$ ($64.5mg\;TAN\;kg\;fish^{-1}\;h^{-1}$) and $20^{\circ}C$ ($83.2mg\;TAN\;kg\;fish^{-1}\;h^{-1}$), respectively. The TAN loss for ingested nitrogen at $20^{\circ}C$ (48.8%) was higher than that for $10^{\circ}C$ (43.0%) and $15^{\circ}C$ (45.7%). This study provides empirical data for estimating ammonia excretion and managing culture management of starry flounder under given temperatures.

• Journal of agricultural medicine and community health
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• v.36 no.2
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• pp.113-119
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• 2011

The aims of this study were to survey, evaluate the accuracy of personal immunization record of vaccination card, and to establish the applicability of personal immunization record for presuming population based immunization rate and evaluation method. In 2005, a population-based survey of 12-35 months old children was carried out in Nonsan, Korea. We conducted household survey and provider check using questionnaire and checklist to obtain data on immunization status for children. Total 11 vaccinations were checked in vaccination card such as BCG, hepatitis b, polio, chickenpox vaccine. For estimating accuracy of immunization status and dates of immunization, we estimated correspondence rate between data from personal vaccination card and data from medical records and immunization registry data. Accuracy of the child's vaccination card by type of National Immunization Program vaccine in whole medical institutions were from 41.8% to 83.2%. Accuracy for the date of vaccination of vaccination card in National Immunization Programme vaccine were from 55.3% to 89.7%. In spite of this study limitations, this study verified the validity of vaccination record of vaccination card substantially, but suggests more efforts to reassure the validity of vaccination card.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.14 no.1
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• pp.12-25
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• 2003

Objectives：As increasing number of new antidepressants have been being introduced in clinical practice, pharmacological understanding has been broadened. These changes mandate new information and theories to be incorporated into the treatment process of children with depressive disorders. In light of newly coming knowledge, this review intended to recapitulate the characteristics of new antidepressants and to consider the pivotal issues to develope guidelines for the treatment of depression in childhood and adolescence. Methods：Searching the Pub-Med online database for the articles with the key words of 'new', 'antidepressants' and 'children' ninety-seven headings of review articles were obtained. The author selected the articles of pertinent subjects in terms of either treatment guideline or psychopharmacology of new antidepressants. When required, articles about the clinical effectiveness of individual antidepressants were separatedly searched. In addition, the safety information of new antidepressants was acquired by browsing the official sites of the United States Food and Drugs Administration and Department of Health and Human Services. Results：1) For the clinical course, treatment phase, and treatment outcome, the reviews or treatment guidelines adopted the information from adult treatment guidelines. 2) Systematic and critical reviews unambiguously concluded that selective serotonin reuptake inhibitors(SSRIs) excelled tricyclic antidepressants( TCAs) for both efficacy and side effect profiles, and were recommend for the first-line choice for the treatment of children with depressive disorders. 3) New antidepressants generally lacked treatment experiences and randomized controlled clinical trials. 4) SSRIs and other new antidepressants, when used together, might result in pharmacokinetic and/or pharmacodynamic drug-to-drug interaction. 5) The difference of the clinical effectiveness of antidepressants between children and adults should be addressed from developmental aspects, which required further evidence. Conclusion：Treatment guidelines for the pharmacological treatment of childhood and adolescence depression could be constructed on the basis of clinical trial findings and practical experiences. Treatment guidelines are to best serve as the frame of reference for a clinician to make reasonable decisions for a particular therapeutic situation. In order to fulfill this role, guidelines should be updated as soon as new research data become available.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.6 no.1
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• pp.141-152
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• 1999

The purpose of this study was to identify correlations among family support, self-esteem and compliance in preventive health behavior in elderly people. The results will provide valuable data for nursing interventions towards help the elderly lead better lives. Those who lived with elderly people in Kimchun were interviewed by the researcher and an assistant. The subjects were 191 elderly people over the age of 65. The study method used was a structured questionnaire and the data were collected from September 17th to September 31th in 1998. The tools for this study were the family support scale designed by Gang Hyun Sook, the self-esteem scale designed by Rosenberg and the preventive health behavior scale designed by Gang Yune Sook. The data were analyzed by the SAS program, Mean, SD, T-test, ANOVA, Pearson Correlation Coefficients. The results of this study are as follows : 1. The mean score for family support was 40.49. The score of family support of the elderly showed significant differences according to age(F=2.66, P<.05), spouse presence(t=4.20, P<.001), family pattern(F=4.56, P<.01), economic status (F=10.47, P<.001) and pocket money(F=10.46, P<.001). 2. The mean score for self-esteem was 29.01. The score of self-esteem of the elderly showed significant differences according to educational level(F=3.47, P<.01), spouse presence(t=2.49, P<.05), family pattern(F=3.79, P<.01), economic staus(F=15.65, P<.001) and pocket money(F=14.04, P<.001). 3. The mean score for compliance with preventive health behavior was 53.15. The score of compliance of preventive health behavior of the elderly showed significant differences according to economic status(F=9.34, P<.001) and pocket money(F=8.13, P<.001). 4. The relation between family support and self-esteem was significantly different(r=.57, P<.001). The relation between family support and compliance with preventive health behavior was significantly different(r=.44, P<.001). The relation between self-esteem and compliance with proventive health behavior was significantey different(r=.51, P<.001), In conclusion, the correlations among lamily support, self-esteem and compliance with preventive health behavior in elderly people showed significant differences.

• Korean Journal of Soil Science and Fertilizer
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• v.46 no.1
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• pp.23-31
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• 2013

Microwave remote sensing can help monitor the land surface water cycle and crop growth. This type of remote sensing has great potential over conventional remote sensing using the visible and infrared regions due to its all-weather day-and-night imaging capabilities. In this paper, a ground-based multi-frequency (L-, C-, and X-band) polarimetric scatterometer system capable of making observations every 10 min was developed. This system was used to monitor the wheat over an entire growth cycle. The polarimetric scatterometer components were installed inside an air-conditioned shelter to maintain constant temperature and humidity during the data acquisition period. Backscattering coefficients for the crop growing season were compared with biophysical measurements. Backscattering coefficients for all frequencies and polarizations increased until dat of year 137 and then decreased along with fresh weight, dry weight, plant height, and vegetation water content (VWC). The range of backscatter for X-band was lower than for L- and C-band. We examined the relationship between the backscattering coefficients of each band (frequency/polarization) and the various wheat growth parameters. The correlation between the different vegetation parameters and backscatter decreased with increasing frequency. L-band HH-polarization (L-HH) is best suited for the monitoring of fresh weight (r=0.98), dry weight (r=0.96), VWC (r=0.98), and plant height (r=0.96). The correlation coefficients were highest for L-band observations and lowest for X-band. Also, HH-polarization had the highest correlations among the polarization channels (HH, VV and HV). Based on the correlation analysis between backscattering coefficients in each band and wheat growth parameters, we developed prediction equations using the L-HH based on the observed relationships between L-HH and fresh weight, dry weight, VWC and plant height. The results of these analyses will be useful in determining the optimum microwave frequency and polarizations necessary for estimating vegetation parameters in the wheat.