• Title/Summary/Keyword: A321

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Inhibitory Effect of Alpiniae officinarum Rhizoma Extract on Degranulation in RBL-2H3 Cells

  • Kim, Eunhee;Ahn, Sejin;Lee, Deug-Chan
    • Korean Journal of Plant Resources
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    • v.28 no.3
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    • pp.321-328
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    • 2015
  • Alpiniae officinarum Rhizoma (the rhizome of Alpinia officinarum Hance, known as lesser galangal), a family of Zingiberaceae, has been used to reduce pain of infection and inflammatory diseases in Asian countries. The present study was focused to evaluate the inhibitory degranulation effect of Alpiniae officinarum Rhizoma extract in RBL-2H3 rat basophilic leukemia cells. Cell viability was measured by MTT assay. RBL-2H3 cells were stimulated by phorbol 12-myristate 13-acetate and calcium ionophore A23187. Mast cell degranulation was analyzed by measuring release of β-hexosaminidase in RBL-2H3 cell. Gene expression was measured by qRT-PCR and signaling molecules were detected by immunoblotting. The Alpiniae officinarum Rhizoma extract suppressed β-hexosaminidase release in dose-dependent manner and inhibited cycloxygenase-2 and tumor necrosis factor-α gene expression. Furthermore, it was found that Alpiniae officinarum Rhizoma extract reduced mitogen-activated protein kinases, especially phosphorylated p38, at 0.75 ㎎/㎖ of Alpiniae officinarum Rhizoma extract concentrations. These data show that Alpiniae officinarum Rhizoma extract has immunosuppressive effect in mast cell induced allergic inflammation.

Production of Hydrolyzed Red Ginseng Residue and Its Application to Lactic Acid Bacteria Cultivation

  • Kim, Dong-Chung;In, Man-Jin
    • Journal of Ginseng Research
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    • v.34 no.4
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    • pp.321-326
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    • 2010
  • Enzymatic treatment conditions for red ginseng residue (RGR) were investigated to apply RGR as a microbial medium. Polysaccharide hydrolyase and protease were screened to obtain high solid and carbohydrate yields, and a good degree of carbohydrate hydrolysis. The optimal dosage and reaction time for Viscozyme, the chosen polysaccharide hydrolyase, were found to be 1.0% (w/w) and 3 h, respectively. Of the tested proteases, Flavourzyme, whose optimal dosage was 0.5% (w/w), was selected. Co-treatment with the optimal dosages of Flavourzyme and Viscozyme increased solid yield, carbohydrate yield, and degree of carbohydrate hydrolysis by 76%, 65%, and 1,865%, respectively, over levels in non-treated RGR. The culture characteristics of Leuconostoc mesenteroides strain KACC 91459P grown in enzymatically hydrolyzed red ginseng residue (ERGR) and RGR suspensions were compared. After cultivation for 6 h, the viable cell counts of both cell suspensions rapidly increased to $1.3{\times}10^9$ colony-forming units (CFU)/g. Moreover, while the viable cell population drastically decreased to $2.4{\times}10^6\;CFU/g$ for cells grown in RGR medium, it was maintained in cells fermented in ERGR medium for 24 h.

Temporal Variation of Phytoplankton Community Related to Water Column Structure in the Korea Strait

  • Lee, Yong-Woo;Park, Hyun-Je;Choy, Eun-Jung;Kim, Yun-Sook;Kang, Chang-Keun
    • Ocean and Polar Research
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    • v.32 no.3
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    • pp.321-329
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    • 2010
  • Photosynthetic pigments, nutrients, and hydrographic variables were examined in order to elucidate the spatio-temporal variation of water column structure and its effect on phytoplankton community structure in the western channel of the Korea Strait in fall 2006 and spring 2007. High phytoplankton biomass in the spring was associated with high salinity, implying that nutrients were not supplied by coastal waters or the Yangtze-River Diluted water (YRDW) with low salinity. Expansion of the Korea Strait Bottom Cold Water (KSBCW) and a cold eddy observed during the spring season might enhance the nutrient supply from the subsurface layer to the euphotic zone. Chemotaxonomic examination showed that diatoms accounted for 60-70% of total biomass, followed by dinoflagellates. Nutrient supply by physical phenomena such as the expansion of the KSBCW and the occurrence of a cold eddy appears to be the controlling factors of phytoplankton community composition in the Korea Strait. Further study is needed to elucidate the mechanisms by which the KSBCW is expanded, and its role in phytoplankton dynamics.

Quality Characteristics of Noodles added with Moringa oleifera Leaf Powder (모링가 잎 분말을 이용하여 제조한 국수의 품질 특성)

  • Kim, Sun-Young;Chung, Chang-Ho
    • Journal of the East Asian Society of Dietary Life
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    • v.27 no.3
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    • pp.321-331
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    • 2017
  • This study investigated the quality of noodles added with Moringa oleifera leaf powder. Noodles were prepared at ratios of 0% (control), 2%, 4%, 6%, and 8% (w/w) Moringa oleifera leaf powder based on flour weight. Land a value of uncooked noodles decreased while b value increased (p<0.001) with the addition of Moringa oleifera leaf powder. Further, L and a value of the cooked noodles decreased while b value increased (p<0.001). Weight, volume, and water absorption of cooked noodles increased with increasing addition of Moringa oleifera leaf powder (p<0.001). pH value of soups decreased while turbidity of soups increased (p<0.001) as amount Moringa oleifera leaf powder increased. Hardness (p<0.001), cohesiveness (p<0.001), chewiness (p<0.001), and adhesiveness (p<0.05) increased significantly while springiness decreased (p<0.01) with increasing addition of Moringa oliefera leaf powder. Total polyphenol content, total flavonoid content, and DPPH free radical scavenging activity increased with increasing addition of Moringa oleifera leaf powder (p<0.001). Noodle prepared with 4% Moringa oleifera leaf powder was the most preferred in terms of overall preference.

Tribological Characteristics of Paraffin Liquid Oil with Nanodiamond and Effects of Surface Hardness on Wear Properties (나노다이아몬드를 첨가한 오일의 트라이볼로지 특성 및 이에 미치는 표면 경도의 영향)

  • Lee, Gyu-Sun;Kim, Hyun-Soo;Lee, Jeong-Hoon;Park, Tae-Hee;Lee, Jung-Suk;Lee, Young-Ze
    • Tribology and Lubricants
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    • v.27 no.6
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    • pp.321-325
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    • 2011
  • Nanodiamond was dispersed in paraffin liquid oil to investigate the effects of nanodiamond at the marginally lubricated condition. Scuffing test and immediate loading sliding wear test were conducted using the fabricated nanodiamond oil. As a result, dispersion of nanodiamond in oil leads to increase in scuffing life, and nanodiamond contents affects the scuffing life. In case of immediate loading sliding wear test, the result was different according to hardness of specimen. If hardness of specimen was low, abrasion of nanodiamond occurred actively. If hardness of specimen was increased, however, nanodiamond can act as a spacer or rolling between contacting surfaces.

Conceptual Design and Manufacturing Scheme of a Gas Generator for 7 tonf Class Rocket Engine (7톤급 로켓엔진 가스발생기 개념설계 및 제작계획)

  • Lim, Byoung-Jik;Kim, Moon-Ki;Kang, Dong-Hyuk;Choi, Hwan-Seok
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2012.05a
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    • pp.451-453
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    • 2012
  • Conceptual design and manufacturing scheme of a gas generator for 7 tonf class rocket engine were described. The combustion chamber pressure, O/F ratio, and total flow rate were decided to be 6 MPa, 0.321, and 1 kg/s respectively in consequence of the engine system design. Based on the parameters conceptual design of the gas generator was carried out and its outer dimension was about ${\Phi}100{\times}250mm$. Most parts of the gas generator to be jointed together by brazing or TIG welding and, if possible, the strength and leakproof tests are to be conducted in every step for checking the welding section.

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A Study on Anomaly Detection Model using Worker Access Log in Manufacturing Terminal PC (제조공정 단말PC 작업자 접속 로그를 통한 이상 징후 탐지 모델 연구)

  • Ahn, Jong-seong;Lee, Kyung-ho
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.29 no.2
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    • pp.321-330
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    • 2019
  • Prevention of corporate confidentiality leakage by insiders in enterprises is an essential task for the survival of enterprises. In order to prevent information leakage by insiders, companies have adopted security solutions, but there is a limit to effectively detect abnormal behavior of insiders with access privileges. In this study, we use the Unsupervised Learning algorithm of the machine learning technique to effectively and efficiently cluster the normal and abnormal access logs of the worker's work screen in the manufacturing information system, which includes the company's product manufacturing history and quality information. We propose an optimal feature selection model for anomaly detection by studying clustering methods.

Synthesis and Characterization of Polyurethane for Artificial Leather Using Bio Polyol (바이오 폴리올을 이용한 인공피혁 코팅용 폴리우레탄의 합성 및 특성)

  • Sur, Suk-Hun;Choi, Pil-Jun;Ko, Jae-Wang;Lee, Jae-Yeon
    • Textile Coloration and Finishing
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    • v.30 no.4
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    • pp.321-328
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    • 2018
  • Wet polyurethane resin was synthesized by using polytrimethylene ether glycol prepared from 1,3-propanediol produced by fermentation from corn sugar as bio polyol and polyether-polyol(PTMG). Physical properties and cell characteristics by wet coagulation were investigated using the synthesized wet polyurethane resin. The tensile strength of wet polyurethane resin decreased with increasing content of bio polyol as copolymer polyol, but it tended to increase elongation at break and tear strength. As a result of thermal characteristic analysis, it was found that the glass transition temperature was slightly increased as the content of bio polyol increased. As a result of comparing the cell characteristics by the wet coagulation method, it was found that the shape of the cell was good when the ether polyol and the bio polyol were used alone.

A Comparison Study on the Perceptions of Parents and Directors of Child-Care Centers regarding Parent Education (어린이집 원장의 기관유형에 따른 부모교육에 대한 인식)

  • Kwon, Yi Jeong
    • Journal of the Korea Convergence Society
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    • v.9 no.12
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    • pp.321-330
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    • 2018
  • The purpose of this study was to investigate the differences in the perception of directors of child-care center about parental education according to types of child-care centers. The subjects were 147 directors of child-care centers who reside in Chungbuk, Sejong, and Jeonbuk. Data were collected through questionnaires. The collected data were analyzed using SPSS 18, and frequency analysis, chi-square method and ANOVA method and Tukey test was also used for the posttest. The results of this study are as follows. There was no difference in the recognition of the director about the necessity of the parental education depending on the type of child-care center. There was a difference in the recognition of the directors in relation to subjects of parental education, the execution method, and evaluation area of parent education.

A Study on Public Service Design Based on Citizen Participation -Focused on Participatory Public Service Design Group- (국민 참여를 통한 공공서비스디자인에 관한 연구 -국민디자인단을 중심으로-)

  • Baek, Su-Hyun;Kim, Sun-Ah
    • Journal of Digital Convergence
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    • v.17 no.9
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    • pp.321-326
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    • 2019
  • This study examines how to realize citizen participation for public service design development. Firstly, after understanding the background of public service development process improvement, the concept of public service design and citizen participation, the summary of how to realize citizen participation for public service design development centered on the Participatory Public Service Design Group. The study found that in order to realize citizen participation, the citizen directly participated in the public service design development process, and it was important to adopt a citizen participation-oriented process and methodology based on service design.