• Journal of Nutrition and Health
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• v.53 no.2
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• pp.141-154
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• 2020

Purpose: Atopic dermatitis (AD), a typical chronic disease in children, is an allergy disease that is highly associated with food. Thus, attention to food intake is needed to prevent and manage it. Therefore, we analyzed differences in food and nutrient intakes depending on AD status in under 12-year-old children. Methods: A total of 2,690 participants were enrolled in this study from the combined 2013-2015 Korea National Health and Nutrition Examination Survey. Subjects were divided into an AD group and normal group (non-AD group). General characteristic, food and nutrients intakes, and prevalence of insufficient and excessive nutrient intake were analyzed using χ² test and regression analyses. The AD odds ratio (OR) for insufficient and excessive nutrient intakes was analyzed using multiple logistic regression analyses. Results: Food and nutrient intakes were not significantly different between the AD and non-AD groups. However, the ratio of calcium intake to recommended nutrient intake was about 70% in both groups, which can be attributed to the overall lack of calcium intake among Korean children. There were no differences in energy or nutrient intakes between the groups, but compared with Korean Dietary Reference Intakes for Koreans, the appropriate intake ratios of fat and vitamin C in the AD group were higher than those in the non-AD group. The AD OR decreased when fat was consumed at above appropriate levels and vitamin C was consumed at lower or excess levels. Conclusion: In children, AD may be related to the nutrient intake ratio of fats and vitamin C, and we speculate that these results were affected by dietary restrictions for AD management.

• Pediatric Infection and Vaccine
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• v.3 no.1
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• pp.76-85
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• 1996

Adenoviruses(Ad) are considered to be second only to rotaviruses as the most significant cause of gastroenteritis in young children in Korea and thus it is essential to know the full spectrum of Ad serotypes routinely present in stool specimens from symptomatic patients. Sixty-six Ad isolates and three questionable ones collected over a 2-year peiord were typed by standard microneutralization, restriction endonuclease digestion and PCR of viral DNA to be able to evaluate these assays comprehensively for their ability to identify Ad associated with gastroenteritis. A total of sixty-one isolates(88.4%) were typed: the predominant types were Ad type 41(Ad41)(26.2%), Ad2(19.7%), Ad40(14.8%), Ad5(9.8%), and Ad7(9.8%) which together accounted for almost 80% of the isolates. The remaining virus isolates were typed as Ad1, 31, 34, 3, 25 and a mixture of 40/41. The incidence of Ad31(4.9%) or Ad3(1.6%) was relatively insignificant. DNA restriction analysis(77.5%) proved to be better than serum neutralization but not so when compared to a PCR-based assay for identification of the enteric Ad serotypes(90%) in stool specimens. In this work, the PCR-based assay was evaluated as a tool for the rapid, yet highly sensitive identification of adenoviral DNA sequences in fresh clinical stool specimens.

• Journal of information and communication convergence engineering
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• v.10 no.2
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• pp.141-148
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• 2012

This paper presents a simple but efficient scheme incorporating a reputation-based approach and a cross-layer approach, called the SIM scheme, for maintaining reliable connectivity and high performance in ad-hoc wireless networks. The SIM scheme incorporates the following two things: an ad-hoc routing scheme with a reputation-based approach exploiting the game theory concept based on an evolutionarily stable strategy, and a cross-layer approach between the network layer and the transport layer employing a reputation-based approach.

• IEIE Transactions on Smart Processing and Computing
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• v.5 no.2
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• pp.117-122
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• 2016

Optimizing the number of ad clicks is a large-scale learning problem that is central to the multi-billion dollar mobile advertising industry. There are currently several optimization methods used, including ad mediation and ad positioning. This paper proposes a new method to optimize mobile advertising by using the ad refresh interval. A new metric, which can measure and compare mobile advertising performance, takes into account time limitations. The results achieved from this optimization study could maximize revenue for mobile advertisers and publishers. This research has high applicability. It also lays out a solid background for future research in this promising area.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.11A
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• pp.1059-1067
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• 2006

AODV(Ad-hoc On-demand Distance Vector) routing protocol was devised for use of mobile nodes in Ad-hoc network. When we use the AODV routing protocol in Ad-hoc networks with high mobility, disturbance of optimized route path and link break occur. In order to solve the shortcomings, this paper proposes a new routing protocol in which new routing control messages are added to the existing AODV. The proposed protocol minimizes link break and transmission delay while is able to secure the optimized route path constantly in changes of network topology The performance of the proposed routing protocol was evaluated by using us2 network simulator. The actual Ad-hoc network test bed provides us the most reliable experimental data for Ad-hoc networks. In order to support this experimental environment, the dissertation also developed an efficient embedded system on which AODV routing protocol, NAT, Netfilter can run and other event message can be verified without declining efficiency. The correct operation of AODV routing protocol has been verified in both the Ad-hoc network test bed in which the embedded system was used, and Ad-hoc networks linked with Ethernet backbone network.

• Speech Sciences
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• v.15 no.2
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• pp.111-118
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• 2008

We identified the characteristic impairmants of linguistic semantic memory in patients with prodromal Alzheimer's disease(AD) and mild AD. To elucidate the earliest changes of semantic language function in subjects with AD, performances on confrontation naming test and verbal fluency task were compared among patients with AD patients (n=20), mild AD patients (n=27) and healthy elderly controls (n=20). Tasks in this study included the confrontation naming test of Test of Lexical Processing in Aphasia(TLPA/Japanese) and one-minute verbal fluency task (semantic/ phonetic categories). The results were as follows: 1) Performances of the prodromal AD group showed the comparable to those of the control group on the confrontation naming test, 2) In the semantic/phonetic verbal fluency tasks, the performances of the control group were better than those of the prodromal AD and mild AD groups, but no significant differences were shown between the prodromal AD and the mild AD group.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.4A
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• pp.309-315
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• 2009

Wireless Ad-hoc networks are dynamic networks that consist of mobile nodes. Nodes in Ad-hoc networks are usually laptops, PDAs or mobile phones. These devices feature Bluetooth and/or IEEE 802.11 (WiFi) network interfaces and communicate in a decentralized manner. Due to characteristics of Ad-hoc networks, Mobility is a key feature of routing protocol design. In this paper, we present an enhanced routing maintenance scheme that cope with topology changes pre-actively. The key feature of the proposed scheme is to switch next-hop node to alternative neighbor node before link breakage for preventing route failure. From extensive experiments by using NS2, the performance of the proposed scheme has been improved by comparison to AODV protocol.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.2
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• pp.51-85
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• 2017

Objectives : This study aimed to investigate the awareness improvement of atopic dermatitis(AD) for AD children's parents and to evaluate the mental health condition of AD children and QoL of their parents. Methods : We conducted elementary school visit education(the first education) and recruited children and parents who wanted to participate the hospital visit education(the Second education). In the first education, we lectured about AD, performed survey about QoL and awareness about AD and obtained 48 valid results. In the second education, we performed an education for AD again, skin condition evaluation, mental health analysis survey and obtained 29 valid results. We compared the AD and non-AD groups of each education in the first and second education. We assessed atopic awareness, FDLQI, DFI, CDI, BAI, and KISE scores by gender, age, duration of disease, onset, and severity of AD. Results : Despite children with AD, the survey showed their parents lacked knowledge about AD. However, they acquired the necessary knowledge in AD education. There was a significant difference in the total score of Atopic awareness between the AD group in the first education and the AD group in the second education. (p=0.042) In addition, the CDI and BAI scores of all patients were divided by the duration of disease, and it was estimated that depression and anxiety disorders may be aggravated by longer term illness. Conclusions and Discussions : This study confirmed duration of AD affects AD children's mental health, and verified positive changes in atopic awareness after AD education.

• Tuberculosis and Respiratory Diseases
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• v.51 no.2
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• pp.135-146
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• 2001

Background : One of the important mechanisms responsible for a tumor escaping the immune response is an absence of the tumor associated antigen (TAA) on the cancer cell surface. To overcome this, combination gene therapy using a herpes simplex thymidine kinase (HSTK) gene, prototype of drug sensitizing gene, was conducted to enhance T AA release by cell destruction, as well as the cytokine genes for immune cell attraction. Methods : We investigated whether or not transduction with the adenovirus-HSTK (Ad-HSTK) enhanced the sensitivity of Lewis lung carcinoma (LLC) to ganciclovir (GCV) and induced a bystander effect. A Tumor vaccine trial was performed using LLC with ad-HSTK$\pm$ad-GM-CSF$\pm$ad-IL-2 to determine if they exhibit some antitumor effect on established lung cancer xenografts. Results : LLC with ad-HSTK revealed a much higher sensitivity to ganciclovir (GCV). LLC transduced with ad-HSTK and/or ad-IL-2, ad-GM-CSF showed a lower in vivo tumorigenicity. In the treatment experiment, vaccination with LLC transduced with ad-HSTK, ad-IL-2, or ad-GM-CSF alone modestly suppressed the growth of an established tumor. Combined transduction with HSTK and GM-CSF induced stronger growth suppression of a established lung cancer, while HSTK and IL-2 combination transduction did not have any antitumor effect on individual transduction. Vaccination with LLC-HSTK-GM-CSF increased the infiltration of dendritic cells in the spleen. Conclusion : It was concluded that a tumor vaccine transduced with HSTK and GM-CSF induces strong antitumor immunity by activating the dendritic cells.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.7
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• pp.1442-1447
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• 2004

In this paper, a 6-Bit CMOS Folding and Interpolating AD Converter is presented. The converter is considered to be useful as an integrated part of a VLSI circuit handling both analog and digital signals as in the case of HDD or LAN applications. A built-in analog circuit for VLSI of a high-speed data communication requires a small chip area, low power consumption, and fast data processing. The proposed folding and interpolating AD Converter uses a very small number of comparators and interpolation resistors, which is achieved by cascading a couple of folders working in different principles. This reduced number of parts is a big advantage for a built-in AD converter design. The design is based on 0.25m double-poly 2 metal n-well CMOS process. In the simulation, with the applied 2.5V and a sampling frequency of 500MHz, the measurements are as follows: power consumption of 27mw, INL and DNL of $\pm$0.1LSB, $\pm$0.15LSB each, SNDR of 42dB with an input signal of 10MHz.