• The Korean Journal of Pain
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• v.14 no.2
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• pp.181-185
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• 2001

Background: Bradycardia frequently occurs in intravenous anesthesia with propofol. Additionally, the thoracic sympathetic nerves influence the heart so that the heart rate (HR) and blood pressure are expected to decrease due to this procedure. Therefore, we measured changes in HR, mean arterial pressure (MAP) and both thumb temperatures before and after thoracic sympathicotomy under total intravenous anesthesia with propofol. Methods: The subjects included 21 outpatients of ASA class I who received thoracoscopic thoracic sympathicotomy under total intravenous anesthesia. Anesthesia was induced with propofol (2 mg/kg) and vecuronium (0.1 mg/kg) and maintained with propofol-fentanyl-oxygen (100%). The surgical procedure was performed at the T3 level in the order of left sympathicotomy (LST) and right sympathicotomy (RST). Measurements of HR, MAP and both thumb temperatures were taken before induction of anesthesia, before and after LST and RST, and 1 hour after the completion of anesthesia. Additionally, the time to the beginning of a rise in temperature in both thumbs after sympathicotomy was recorded. Results: HR did not show any significant difference before or after sympathicotomy, however it decreased at 1 hour after the completion of anesthesia. MAP decreased after LST and decreased further after RST. Left thumb temperature began to increase at $45.8{\pm}10.7$ seconds after LST. Right thumb temperature initially decreased after LST and increased from $45.2{\pm}11.8$ seconds after RST. Subsequently, both increased temperatures were maintained at 1 hour after the completion of anesthesia. Conclusions: Although HR and MAP decreased, there were no severe hemodynamic changes. An increase in the thumb temperature was confirmed within 1 minute after sympathicotomy on the same side.

• Mycobiology
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• v.46 no.2
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• pp.168-171
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• 2018

In 2016, a severe leaf spot disease was found on Iris ensata Thumb. in Nanjing, China. The symptom was elliptical, fusiform, or irregularly necrotic lesion surrounded by a yellow halo, from which a small-spored Alternaria species was isolated. The fungus was identified as Alternaria iridiaustralis based on morphological characteristics. The pathogenicity tests revealed that the fungus was the causal pathogen of the disease. Phylogenic analyses using sequences of ITS, gpd, endoPG, and RPB2 genes confirmed the morphological identification. This study is the first report of A. iridiaustralis causing leaf spots on I. ensata in China.

• The Journal of Korea Robotics Society
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• v.7 no.1
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• pp.1-8
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• 2012

A humanoid robot hand with one thumb and two fingers has been developed. Each finger has the specially designed compact joints, called "MEC Joint", which convert the rotation of a motor to the swing motion of a pendulum. The robot hand with the MEC Joints is compact and relatively light but strong enough to grasp objects in the same manner as human being does in daily activities. In this paper the kinematic model and the torque characteristics of the MEC Joint are presented and compared with the results of the dynamic simulation and the dynamometer test. The dynamic behavior of the thumb and two fingers with MEC Joints are also presented by computer simulation.

• Journal of Korean Institute of Industrial Engineers
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• v.39 no.2
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• pp.99-104
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• 2013

With diversity of mobile services (e.g., messenger, and social network service) on smartphone, the demand of text input using a soft keyboard is increasing. However, studies on subjective and physiological responses of users for various touch locations are lacking. The present study investigated the ergonomic effects according to touch locations of a soft keyboard on smartphone. The experiment of the present study measured perceived discomfort using Borg's CR-10 scale and electromyography (EMG) on forearm (abductor pollicis longus, and extensor digitorum communis) and thumb (abductor pollicis brevis, and first dorsal interossei) muscles. Perceived discomfort was significantly varied from 0.7 (extremely weak discomfort) to 2.5 (weak discomfort) depending on touch locations. %MVC according to touch locations was only significant at abductor pollicis brevis which varied from 10% to 23%. The experimental results of the present study can be utilized in the ergonomic design of a soft keyboard.

• Archives of Plastic Surgery
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• v.36 no.4
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• pp.497-499
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• 2009

Purpose: Leiomyoma is a rare benign tumor of nonstriated muscles. Leiomyoma is most commonly found in the uterus and rarely occur in the hand. 150 cases of leiomyoma of the hand have been reported in the English literature; however, to the best of our knowledge only four of these have been in children and none were reported in Korean literature. We present a case of leiomyoma in the hand of a 8 - year - old boy, which is a rare site for localization and unusual for age. Methods: A 8 - year - old boy presented with a painless mass on the ulnar side of his thumb. Physical examination revealed a $1.2{\times}1.2cm$ round, rubbery mass that was nontender to palpation. The vascular, sensory, and motor exams were otherwise unremarkable. Further evaluation with CT demonstrated an enhancing mass at dorsoulnar aspect of 1st proximal phalangeal region suggestive of a hemangioma versus other enhancing solid mass. The diagnosis of a leiomyoma was confirmed following surgical excision with histologic evaluation. Results: At 3 months follow - up, the incision was healed, motor and sensory function were intact, and there were full range of motion. Neither recurrence nor postoperative complication were observed. Conclusion: Leiomyoma is a rare tumor of the hand, especially in children. Diagnosing hand tumors in children is more difficult than in adults, hand surgeons should be aware of the diagnostic possibilities based on examination and imaging of a hand tumor ; however, surgical excision with histologic examination is required for definitive diagnosis.

• Archives of Plastic Surgery
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• v.38 no.4
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• pp.398-400
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• 2011

Purpose: Subungual tumors are a common cause of nail plate deformity, and may be caused by fibrokeratoma, Koene's tumor and glomus tumors. Neurofibromas, either as part of neurofibromatosis or as a solitary tumor are exceptionally rare in the digits. Methods: A 44-year-old man presented with painless onychodystrophy and nail plate elevation of the right thumb due to a small subungual mass that had started growing 3 years ago. Sensory evaluation of the distal phalanx was normal, and no discoloration nor infection signs were seen. The nail plate was extracted under local anesthesia, and the mass was delicately removed without injury to the nail bed. The nail matrix was repaired with primary closure. Results: Histopathology shows a well circumscribed, cellular tumor with myxoid stroma. Tumor cells were S-100 protein positive, and the patient was diagnosed with myxoid neurofibroma. There has been no sign of recurrence to date, 14 months after the operation. Conclusion: Presentation of cutaneous neurofibromas in the digits is an uncommon finding. They may occur as a manifestation of neurofibromatosis or as a solitary tumor. Subungual neurofibromas are exceptionally rare. To our knowledge, there are only ten reports of solitary subungual neurofibroma unrelated to neurofibromatosis to date. We report a rare case of solitary subungual myxoid neurofibroma of the thumb, that was treated through total excision, with preservation of the nail matrix.

• Journal of Korean Society of Forest Science
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• v.3 no.1
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• pp.23-27
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• 1963

A research was made through a experimental cultivation during a period of 7 years (1956~1962) to determine the yearly yield, the total gross yield over 7 year's period and the maximum availability of stock timbers used as the germination bed of cortinellus edodes (Berk) Ido et Imai. The results are summarized as follows : (1) Research and plot scheme: Two experimental plots were established-plot "A" in the experimental forest of this college; plot "B" in the campus woods, 400 timber beds were furnished in each. The kinds of timbers used are : Quercus Serrata Thumb 140. Quercus acutissima Carr. 140, Quercus crispula BI 120. The environmental condition in plot "A" was better then that in plot "B" and the former showed greater yield than the latter. (2) yield : In plot "A" the total yield was 58.875kg and some of the timbers was still continuing germ in this seven after closing of the plot. In plot "B" the total yield was 56.90kg and after the sixth year no more germination was observed. In conclusion, plot "A" showed greater yield and longer germination than plot "B". (3) Germination efficacy and the kinds of timber: The best result was abserved on Quercus serrata, thumb Quercur acutissima Carr, stood next and then came Quercus crispula BI. Betula platyphylla was tried, but the result was worst. (4) Availability limits of timber beds: Quercus serrata Thumb with diameter 12~15cm had the longest availability more than (6~7 years) and Quercus acutissima Carr with diameter 12~15cm showed 6~7 year's availability. The shortest availability was found in Quercus crispula with diameter 6~9cm. Any kinds of timber with diameter 6~9cm had only 4~5 years of availability (5) In the table showing the yearly germination quantity, the figure of December and Jaunary of the 4th and 5th year shows the yield obtained in the semi-cellar paper house. This tells that there is good promise of winter cultivation of cortinellus edodes (Berk) Ido et Imai on matured timber beds.

• IE interfaces
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• v.20 no.4
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• pp.539-546
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• 2007

This study has been conducted on touch screen interface design for mobile devices. It was intended to measure user’s satisfaction on one-handed thumb input mobile devices. Recent studies proposed the optimal touch button size, but it is inappropriate for mobile devices. Therefore, this study was focused on four touch key factors-width, height, the horizontal and vertical distance between touch keys-as independent variables. The ANOVA results showed that the user satisfaction of four touch key factors was significantly affected by the thumb input. It also apparent that the interactions between four factors were significant. As a result, the horizontal and vertical distance as well as the width and height affected the satisfaction of users. In addition, this study suggested satisfaction models which represent the top 30%, 50%, 70% of user satisfaction measurement. The results of this study could be used to design touch keys that are able to enhance the usability on touch screen based mobile devices.

• The Journal of Korean Physical Therapy
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• v.16 no.4
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• pp.218-225
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• 2004

OBJECTIVES: This study was performed to find out static two-point discrimination (TPD) in fingertips. METHODS: This was a cross-section, measure study of static two-point discrimination involving healthy young adults. Measure was completed by 48 college students in Andong Science College from June 1 to 12, 2004. The minimal distance at which two-points could be discriminated was measured from thumb to little finger. RESULTS: For dermatomal regions of the fingertip, mean values ranged from 3.3mm to 4.9mm (thumb 3.6mm, index finger 3.3mm, middle finger 3.8mm, ring finger 4.2mm, and little finger 4.7mm in the left hand; thumb 3.7mm, index 3.5mm, middle 4.0mm, ring 4.3mm, and little 4.9mm in the right hand). A significant difference in discrimination ability was found between men and women, 3.5mm for women showed a greater sensitivity than 4.1mm for men in the left middle fingertip(p=0.0109), also 3.9mm for women showed a greater accuracy than 4.5mm for men in the left ring fingertip(p=0.0388). In the right index fingertip, women (3.1mm) have a narrow distance than men (3.6mm)(p=0.0329). The minimal distance of TPD was found a significant difference between 20 and 30 years in age. 4mm for 30 years showed a greater distance than 3.5mm for 20 years in the left thumb fingertip(p=0.0354), also, 3.8mm for 30 years showed a greater distance than 3.2mm for 20 years in the left index fingertip(p=0.0174), and 4.3mm for 30 years showed a greater distance than 3.7mm for 20 years in the left middle fingertip(p=0.0444). In the right index fingertip, 20 years (3.2mm) had also a narrow distance than 30 years (4.1mm)(p=0.0020), 20 years (3.9mm) showed a narrow distance than 30 years (4.6mm) in the right middle fingertip(p=0.0124), and 20 years (4.1mm) showed a greater sensitivity than 30 years (5.0mm) in the right ring fingertip(p=0.0070). CONCLUSIONS: Our results suggest that distance of TPD in the both index fingertips for 20 years women was significantly narrowed.

• Journal of the Korean Magnetic Resonance Society
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• v.12 no.1
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• pp.1-13
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• 2008

Acetyl-CoA carboxylase (ACC) catalyzes the first step in fatty acid biosynthesis: the synthesis of malonyl-CoA from acetyl-CoA. As essential regulators of fatty acid biosynthesis and metabolism, ACCs are regarded as therapeutic targets for the treatment of metabolic diseases such as obesity, In ACC, the biotinoyl domain performs a critical function by transferring an activated carboxyl group from the biotin carboxylase domain to the carboxyl transferase domain, followed by carboxyl transfer to malonyl-CoA. Despite the intensive research on this enzyme, only the bacterial and yeast ACC structures are currently available, To explore the mechanism of ACC holoenzyme function, we determined the structure of the biotinoyl domain of human ACC2 and analyze its characteristics using NMR spectroscopy. The 3D structure of the hACC2 biotinoyl domain has a similar folding topology to the previously determined domains from E. coli and P. Shermanii, however, the 'thumb' structure is absent in the hACC2 biotinoyl domain. Observations of the NMR signals upon the biotinylation indicate that the biotin group of hACC2 does not affect the structure of the biotinoyl domain, while the biotin group for E. coli ACC interacts directly with the thumb residues that are not present in the hACC2 structure. These results imply that, in the E. coli ACC reaction, the biotin moiety carrying the carboxyl group from BC to CT can pause at the thumb of the BCCP domain. The human biotinoyl domain, however, lacks the thumb structure and does not have additional non-covalent interactions with the biotin moiety; thus, the flexible motion of the biotinylated lysine residue must underlie the "swinging arm" motion. This study provides insight into the mechanism of ACC holoenzyme function and supports the "swinging arm" model in human ACCs.