Browse > Article

Solitary Subungual Myxoid Neurofibroma of the Thumb: A Case Report  

Seo, Bom-Mie (Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea)
Lim, Jin-Soo (Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea)
Jung, Sung-No (Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea)
Yoo, Gyeol (Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea)
Byeon, Jun-Hee (Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea)
Publication Information
Archives of Plastic Surgery / v.38, no.4, 2011 , pp. 398-400 More about this Journal
Abstract
Purpose: Subungual tumors are a common cause of nail plate deformity, and may be caused by fibrokeratoma, Koene's tumor and glomus tumors. Neurofibromas, either as part of neurofibromatosis or as a solitary tumor are exceptionally rare in the digits. Methods: A 44-year-old man presented with painless onychodystrophy and nail plate elevation of the right thumb due to a small subungual mass that had started growing 3 years ago. Sensory evaluation of the distal phalanx was normal, and no discoloration nor infection signs were seen. The nail plate was extracted under local anesthesia, and the mass was delicately removed without injury to the nail bed. The nail matrix was repaired with primary closure. Results: Histopathology shows a well circumscribed, cellular tumor with myxoid stroma. Tumor cells were S-100 protein positive, and the patient was diagnosed with myxoid neurofibroma. There has been no sign of recurrence to date, 14 months after the operation. Conclusion: Presentation of cutaneous neurofibromas in the digits is an uncommon finding. They may occur as a manifestation of neurofibromatosis or as a solitary tumor. Subungual neurofibromas are exceptionally rare. To our knowledge, there are only ten reports of solitary subungual neurofibroma unrelated to neurofibromatosis to date. We report a rare case of solitary subungual myxoid neurofibroma of the thumb, that was treated through total excision, with preservation of the nail matrix.
Keywords
Neurofibroma; Nail diseases; Onychodystrophy;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Salasche SJ, Garland LD: Tumors of the nail. Dermatol Clin 3: 501, 1985
2 Sugiura K, Sugiura M, Hayakawa R, Kato Y, Sakamoto N, Osada A, Shinzato M, Shamoto M: Solitary neurofibroma: an uncommon location. Int J Dermatol 43: 451, 2004   DOI   ScienceOn
3 Dangoisse C, Andre J, De Dobbeleer G, Van Geertruyden J: Solitary subungual neurofibroma. Br J Dermatol 143: 1116, 2000
4 Baran R, Haneke E: Subungual myxoid neurofibroma on the thumb. Acta Derm Venereol 81: 210, 2001   DOI   ScienceOn
5 Bhushan M, Telfer NR, Chalmers RJ: Subungual neurofibroma: an unusual cause of nail dystrophy. Br J Dermatol 140: 777, 1999
6 Niizuma K, Iijima KN: Solitary neurofibroma: a case of subungual neurofibroma on the right third finger. Arch Dermatol Res 283: 13, 1991   DOI   ScienceOn