• Journal of Cardiovascular Imaging
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• v.30 no.3
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• pp.153-168
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• 2022

Recent studies have shown that sodium/glucose cotransporter 2 (SGLT2) inhibitors might exert favourable changes on cardiac parameters as observed on cardiovascular imaging. We conducted a systematic review and meta-analysis to determine the effects of SGLT2 inhibitors on cardiac imaging parameters. Four electronic databases (PubMed, Embase, Cochrane, Scopus) were searched for studies in which the effects of SGLT2 inhibitors on cardiac imaging parameters were examined. Studies in which a population was administered SGLT2 inhibitors and analysed by echocardiography and/or cardiac magnetic resonance (CMR) imaging were included. Random-effects pair-wise meta-analysis models were utilized to summarize the studies. A total of 11 randomized controlled trials was included with a combined cohort of 910 patients. Comparing patients receiving SGLT2 inhibitors with subjects receiving placebo, the mean change in CMR-measured left ventricular mass (LVM) was -3.87 g (95% confidence interval [CI], -7.77 to 0.04), that in left ventricular end-systolic volume (LVESV) was -5.96 mL (95% CI, -10.52 to -1.41) for combined LVESV outcomes, that in left atrial volume index (LAVi) was -1.78 mL/m² (95% CI, -3.01 to -0.55) for combined LAVi outcomes, and that in echocardiography-measured E/e' was -0.73 (95% CI, -1.43 to -0.03). Between-group differences were not observed in LVM and LVESV after indexation. The only between-group difference that persisted was for LAVi. Treatment with SGLT2 inhibitors resulted in reduction in LAVi and E/e' on imaging, indicating they might have an effect on outcomes associated with LV diastolic function.

• The Korean Journal of Nuclear Medicine Technology
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• v.15 no.2
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• pp.76-82
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• 2011

Purpose: Lymphoscintigraphy is absolutely being used standard examination in lymphatic diagnosis, evaluation after treatment, and it is useful for lymphedema to plan therapy. In case of lymphoscintigraphy of lower-extremity lymphedema, it had an effect on results if patients had not pose same position on the examination of 1 min, 1 hour and 2 hours after injection. So we'll study the methods to improve confidence with minimized quantitative analysis errors by influence factors. Materials and Methods: Being used the Infinia of GE Co. we injected $^{99m}Tc$-phytate 37 MBq (1.0 mCi) 4 sylinges into 40 people's feet hypodermically from June to August 2010 in Samsung Medical Center. After we acquired images of fixed and unfixed condition, we confirmed the count values change by attenuation of soft tissue and bone according to different feet position. And we estimated 5 times increasing 2 cm of distance between $^{99m}Tc$ point source and detector each time to check counts difference according to distance change by different feet position. Finally, we compared 1 and 6 min lymphoscintigraphy images with same position to check the effect of quantitative analysis results owing to difference of amounts of movement of the $^{99m}Tc$-phytate in the lymphatic duct. Results: Percentage difference regarding error values showed minimum 2.7% and maximum 25.8% when comparing fixed and unfixed feet position of lymphoscintigraphy examination at 1 min after injection. And count values according to distance were 173,661 (2 cm), 172,095 (4 cm), 170,996 (6 cm), 167,677 (8 cm), 169,208 counts (10 cm) which distance was increased interval of 2 cm and basal value was mean 176,587 counts, and percentage difference values were not over 2.5% such as 1.27, 1.79, 2.04, 2.42, 2.35%. Also, Assessment results about amounts of movement in lymphatic duct within 6 min until scanning after injection showed minimum 0.15%, and maximum 2.3% which were amounts of movement. We can recognize that error values represent over 20% due to only attenuation of soft tissue and bone except for distance difference (2.42%) and amounts of movement in lymphatic duct (2.3%). Conclusion: It was show that if same patients posed different feet position on the examination of 1 min, 1 hour and 2 hours after injection in the lymphoscintigraphy which is evaluating lymphatic flow of patients with lymphedema and analyzing amount of intake by lymphatic system, maximum error value represented 25.8% due to attenuation of soft tissue and bone, and PASW (Predictive Analytics Software) showed that fixed and unfixed feet position was different each other. And difference of distance between detector and feet and change of count values by difference of examination beginning time after injection influence on quantitative analysis results partially. Therefore, we'll make an effort to fix feet position and make the most of fixing board in lymphoscintigraphy with quantitative analysis.

• 월간산업보건
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• s.8
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• pp.4-30
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• 1988

Examination of working environments was conducted to get more detailed data about harmful working environments and to make a contribution to more effective management. Study was carried out on 722 factories located in Taegu city and eight counties in Kyungpook Province, Korea, for a period of one year, from February 1 to December 30, 1986. The total number and proportion of workers exposed to harmful material was 37,697, 45.2% among 83,368 workers. The results according to exposed material were as follows: 1. In the case of noise, proportion of exceeding the 8-hour TLV was 59%, Included were nail-cutting in assembly metal manufacturing industry and weaving process in textile. 2. Dust in mill process of coal manufacturing industries exceeded the TLV of second class of dust at all parts and exceeded the TLV at 6% as a whole.: 3. The fields of industry lower than 70 lux of illumination were storage equipment of food, auto-winder of textile, painting of wood wares and coal mixing, and 44% of all cases was lower than standard. 4. As a result of temperature index investigation(WBGT), about 12% of all sujects exceeded limit value. Included parts were rolling machine and reducing room. 5. In the case of organic solvents, TLV was exceeded at about 8%, The parts exceeded TLV according to materials belonged to this category were as follows. 1) Toluene: adhesive work in assembly metal manufacturing 2) Xylene: printing and paint mixing in chemical manufacturing 3) Methyl ethytl ketone: paint mixing in all parts examined and coating machine partially in chemical manufacturing 4) Methyl isobutyl ketone: printing in chemical manufacturing 5) Acetone: vapor polishing in assembly metal manufacturing 6. Among specified chemical materials, the concentration of HC1 in the air in metal assembly manufacturing factory exceeded TLV. in one of three assembly metal manufacturing examined. Others, such as benzene, acetic acid, formic acid, sodium hydroxide, formalin, ammonia, copper, chromate etc. were lower than TLV in its indoor atmospheric concentration. As a whole, the proportion of exceeding TLV was about 0.8% 7. The concentrations of inorganic lead were lower than TLV in all parts examined. The results of this investigation show the fact that current management of working environments is not satisfactory, and so more active management is needed.

• The Journal of Sustainable Design and Educational Environment Research
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• v.16 no.2
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• pp.19-33
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• 2017

The purpose of this study is to derive education programs for safety training class, create unit spaces and present components and methods of utilizing the spaces for the development of facilities models closely related to various policy, operation plan and facility construction projects promoted by related institutions such as the Ministry of Education, schools, architects and companies. This study is divided into five steps. First, we reviewed the literature related basic directions for safety education and facility plan, second, field survey included both field conditions such as spatial size and facility configuration and analysis of operating conditions like hours of operation and personnel. Base on literature review and field survey, it were used to analyze strengths and weaknesses of existing safety training classes, and five facility models was developed based on the Delphi method and expert participatory design. The result show that the facility models (drafts) of safety training class were developed as follows: (1)the facility model for traffic safety(pedestrian safety, vehicle safety, subway safety) (2)the facility model for first aid(emergency rescue, how to report) (3)the facility model for disaster safety(fire evacuation safety, life earthquake safety) (4)the facility model for elevator safety(elevator safety, escalator safety) (5)the facility model for drugs and violence safety (smoking drinking, sexual harassment safety, food safety) The safety training class can be composed by combining or separating each module according to affordable space size of each school.

• Journal of Marine Bioscience and Biotechnology
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• v.7 no.1
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• pp.1-10
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• 2015

Bio diesel has advantages to reduce GHG(Greenhouse Gas) compare with the fossil fuel by using oil comes from plant/animal sources and even waste such as used cook oil. The diversity of energy feeds brings the positive effects to secure the national energy mix. In this circumstance, micro-algae is one of the prospective source, though some technical barriers. We analyzed the bio diesel which was derived from Dunaliella tertiolecta LB999 through the BD100 quality specifications designated by the law. From that result, it is revealed that the oxidation stability is one of the properties to be improved. In order to find the reason for low oxidation stability, we analyzed the oxidation tendency of each FAME components through some methods(EN 14111, EN14112, EN16091). In this study, we could find the higher double bond FAME portion, the more oxidative property(C18:1${\ll}C18:3$) in bio diesel and main unsaturated FAME group is acted as the key component deciding the bio diesel's oxidation stability. It is proved experimentally that C18:3 FAME are oxidized easily under the modified accelerated oxidation test. We also figure out low molecular weight hydrocarbon and FAME were founded as a result of thermal degradation. Some alcohol and aldehydes were also made by FAME oxidation. In conclusion, it is necessary to find the way to improve the micro-algal bio diesel's oxidation stability.

• Journal of the Korean Recycled Construction Resources Institute
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• v.4 no.3
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• pp.322-329
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• 2016

This study is about the method to control the quality of material used to repair leakage and crack of concrete structure and suggests the "Temperature Stability Test Method" as a follow-up study. In the result of performance evaluation for 45 samples of 15 types in 5 series, the temperature stability test showed different material changes including rolling down, volume change, and color change as they are frozen and melt repeatedly in the somewhat extreme conditions at low($-20^{\circ}C$) and high($60^{\circ}C$) temperatures, where 13 samples (approx. 29%) and 32 samples (approx. 71%) showed leakage, respectively, in the permeability test to evaluate leakage. This result shows the enough importance of setting the quality control criteria of leakage repair material currently used to maintain concrete structures considering the temperature conditions, and proves the applicability of the Temperature Stability Test Method as a standard test method to ensure long-term durability of concrete structure.

• Proceedings of the KOR-KST Conference
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• 1996.02a
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• pp.29-58
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• 1996

현재 서울은 교통사고문제, 교통혼잡문제와 자동차로부터 배출되는 유해가스에 의한 대기환경오염문제를 갖고 있다. 본 논문의 목적은 대기환경오염을 악화시키는 자동차의 주된 배출오염가스인 일산화탄소, 탄화수소 및 질소화합물량을 교차로 교통량을 중심으로 어떻게 계산하는가에 있다. 연구의 대상지역은 서울시의 송파구 교차로들과 도심지역의 링크들을 선택하였다. 그리고 교통량, 지체시간, 링크길이, 정지회수, 운행속도, 주행속도 등을 고려하여, 제작차 배출가스 허용기준, 총량기준, 불량차 기준, 속도기준 등에 의한 계수산정 및 TRAF-NETSIM에 의한 시뮬레이션을 통하여 일정 도로상의 제한된 범위내의 배출량 산출을 시도하였다. 본 연구의 결과에 의하면 첫째, 어느 방법이든 실제배출량의 정확한 값을 표현 할 수는 없는 것이고, 단지 상대적인 비교에 의하면 배출가스량의 수준을 추정 할 수 있었다. 또한, 시뮬레이션 배출율표를 우리 현실에 맞는 자료에 의해 수정할 수 있다면, 그 결과는 실제량에 보다 근접할 수 있을 것이다. 둘째, 서울도로의 현재 혼잡상태에서 속도의 저감에 배출량이 민감한 반응을 보이고 있다는 사실이다. 셋째, 교통량변화에 따른 배출량의 변화가 일산화탄소에서 가장 심하게 나타남을 알 수 있었고, 신호운영상의 옵셋값이 잘못 설정되면 탄화수소는 35%, 일산화탄소는 40%, 질소산화물은 75%까지 초과발생할 수 있으며, 유해배출가스량을 최소화시키는 측면에서의 신호최적화를 위해서는 현재의 Stop Penalty는 상향 조정되어야 함이 밝혀졌다. 앞으로는 자동차로 인한 대기환경오염 농도의 저감을 위해서는 도로별 자동차 유해가스 배출 총량규제 방안도 고려해 볼 가치가 있으며, 이를 위해 환경공학과 교통공학의 다학제적 공동연구가 지속적으로 필요하며 교통정책에 반영되어야 할 것이다.분석, 리용수 학모형대이십일세기상해항공운량진행예측, 제출발전상해항공운수적전 략목표급발전중점. 예측2020년 상해항공항총객운탄토량4300만인/년, 화운량달120만돈; 2050년객운량장달18150만인차/년, 화운량518만돈. 사, 발전상해민항기출경제정책, 제출위료$\ll$진흥상해, 개발포동, 복무전국, 면향세계$\gg$ 화도이십일세기중기국민경제달도중등발달국가수 평굉관전략목표적실현, 제료필수재지도사상상파교통운수진정방도전략 산업지위, 환응재관리체제상채취과단유효적개혁조시, 재기출경제정책 상급여대력부지. 오, 전략목표, 위파상해건설성위태평양서안최대적경제, 김융, 무역적중심, 요구상해항공항성위화동지구통향세계각지항선망출발참, 구성대외개방선면축심, 실현국제항선적함접화국내항반적전항, 형성다축심복사식항선망; 가강기장건설, 개피포동제이국제기장건설, 괄응포동개발경제발전적수요. 부화개시일은 각 5월 26일과 5월 22일이었다. 11. 6월 중순에 애벌레를 대상으로 처리한 Phenthoate EC가 96.38%의 방제가로 약효가 가장 우수하였고 3월중순 및 4월중순 월동후 암컷을 대상으로 처리한 Machine oil, Phenthoate EC 및 Trichlorfon WP는 비교적 약효가 낮았다.>$^{\circ}$E/$\leq$30$^{\circ}$NW 단열군이 연구지역 내에서 지하수 유동성이 가장 높은 단열군으로 추정된다. 이러한 사실은 3개 시추공을 대상으로 실시한 시추공 내 물리검층과 정압주입시험에서도 확인된다.. It was resulted from increase of weight of single cocoon. "Manta"2.5ppm produced 22.2kg of cocoon. It is equal to 9% increase i

• Korean Journal of Veterinary Service
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• v.32 no.3
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• pp.201-207
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• 2009

Porcine transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV) and rotaviruses are considered as the most important causative agents of diarrhea in piglets. The study established 3 method vaccination programs to prevent PEDV. A (LL)group inoculated twice vaccinations on 2-weeks-interval during the late term of pregnant sows with PEDV live vaccine. The B (LKK) group was applied that one time single PEDV live vaccine at the pre-mate followed by the TGEV PEDV combined inactivated vaccine (twice vaccination on 2-weeks interval at the third-trimester). C (KK) group was applied to sow which inoculated twice vaccination on 2-weeks-interval during the late term of pregnant sows with by the TGEV, PEDV combined inactivated vaccine. As the result of SN test on sows in the pig farm before vaccination, antibody titers was showed 9/45 (20.0%). By comparison with the serum neutralizing antibody titers against PEDV of the vaccination programs after PEDV of the vaccination, A group and B group vaccination method was higher than those of C group in sows. In the piglets up to 2 weeks of age, A group was showed antibody titers of 17/22 (81.8%) that showed 2-128, and B group was showed antibody titers of 30/37 (81.1%) that showed 2-512, and C group was showed antibody titers of 14/28 (50.0%) that showed 2-32. On the other hand, PEDV antibody titers were tested for the survey. As the results of SN test, Aujeszky's disease survey in 54 pig farms from november 2005 to august 2006, antibody titers of 47/286 (16.4%) showed above 2. Five breeding farms were antibody titers of 38/77 (49.4%), Wanggung zone farms antibody titers of 59/85 (69.4%). In pigs farms vaccinated the first of twice PEDV live vaccine, and after 6 month, the second of twice TGEV PEDV combined inactivated vaccine (LLKK, 256-1024 titer) method was higher than those of vaccinated twice the early term of pregnant, and twice the late term of pregnant sows of PEDV live vaccine (LLLL, 32 titer).

• Korean Journal of Ichthyology
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• v.22 no.4
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• pp.256-266
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• 2010

The distribution characteristics of the eggs and larvae of anchovy Engraulis japonica, and environmental factors in the southern coastal waters of Korea were investigated from May to August 2009. Eggs and larvae were mainly distributed in the waters off Naro Island, Namhae Island and Saryang Island. High densities of eggs and larvae in temperatures of $19.0{\sim}24.0^{\circ}C$, salinites of 33.0~34.4 psu, DO of 6.05~8.13 mg/L and chlorophyll-a $1.2{\sim}2.3{\mu}g/L$ were observed. Water temperature in the coastal region was higher than that in the open sea, while salinity was lower. Evidence of sea water intrusion toward Sori Island and Maemul Island, and an inner-water intrusion from Yeoja Bay, Gamak Bay and Gwangyang Bay were observed. High densities of eggs in early developmental stage occurred in waters off Naro Island, Dolsan Island and Namhae Island, but high densities of eggs in a later developmental stage occurred in waters off Yokji Island and Maemul Island. During the survey period, the proportion of later developmental-stage eggs was higher in the eastern part of the study area.

• Korean Journal of Ecology and Environment
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• v.36 no.3 s.104
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• pp.242-256
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• 2003

This study aimed to determine the relationship between rainfall-discharge patterns and maior aquatic environmental factors in a river-type reservoir. Specifically, daily monitoring was conducted in Paltang Reservoir from January 1999 to December 2001. Observation of the daily changes of the environment factors showed that natural meteorological factors and hydrological factors causing the change of water discharge had a major effect on the aquatic environment. Rainfall was the main source of hydrological changes, with its frequency a possible direct variable governing the range of discharge changes. Rainfall was weak in November${\sim}$May and heavy in June${\sim}$October (heavist in summer). The range of water discharge was greatest during summer (July to September) and lowest during winter (January to February). A principal component analysis (PCA) showed that aquatic environmental factors could be classified into three different types in the pattern of annual variation. First, type I included water temperature, turbidity, water color and organic matter (COD), which increased with increasing water discharge. Second, type ll consisted of DO and pH, which decreased with increasing water discharge. Third, type III included conductivity, alkalinity and chloride ion, which showed middle values with increasing water discharge. Monthly variation of aquatic environments explained by the first two dimensions of the PCA suggests that aquatic environments of Paltang Reservoir may have annual cycle typical of river-type reservoirs depending on hydrological factor such as water discharge.