• 한국광학회지
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• 제5권4호
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• pp.457-460
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• 1994

XeCl 레이저 증폭기의 포화 에너지 밀도와 소신호 이득계수를 활성기체의 압력을 변화시키면서 측정하였다. Xe이 30mb, He이 2000mb일 때, HCl이 34, 52, 73, 92으로 압력이 높아짐에 따라 포화 에너지 밀도는 1.3, 1.45, 2.0, $2.3mJ/\textrm{cm}^2$로 거의 선형적으로 증가하였지만 소신호 이득계수는 6.5, 7.5, 7.0, 7.0%/cm로 거의 변화하지 않았다.

• 한국전자파학회논문지
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• 제16권2호
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• pp.139-143
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• 2005

본 논문에서는 $CMOS\;0.18\;{\mu}m $ 공정을 이용하여 MB-OFDM UWB용 RF 수신기의 광대역 LNA와 Down-mixer를 설계하였다. 광대역 LNA는 $3\~5\;GHz$의 대역에서 전력이득은 $12.8\~15dB$, 잡음지수는 2.6 dB 이하, 그리고 입력 IP3는 4 GHz에서 -8 dBm의 특성을 나타내고, 입출력 반사손실은 10 dB 이하의 특성을 보인다. Down-mixer는 3개의 채널에서 2 dB 이하의 gain flatness를 나타내고, 변환이득은 $-2.9\~0.4dB$의 특성을 나타낸다. 또한 LO의 leakage와 feedthrough는 각각 30 dB 이상의 특성을 나타내도록 설계하였다.

• 상하수도학회지
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• 제14권4호
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• pp.350-355
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• 2000

Powdered activated carbon(PAC) is widely used to control 2-MIB와 geosmin causing earthy-musty odor in water supplies. It was known that chlorine is one of the chemicals often come into contact with activated carbon. But activated carbon react with chlorine and surface oxide accumulate on carbon surface. As result, adsorption capacity of activated carbon is reduced. To investigate the effect of chlorine on the PAC's ability to adsorb 2-MIB and Geosmin, a series of experiments was carried out to show (1) the effect of aqueous chlorine doses on the ability of PAC to adsorb 2-MIB and Geosmin from Lake Heodong water. (2) the effect of delaying the chlorine addition after PAC had been added (to simulate the effect of using an alternative point of chlorine addition). As a result of experiment, as chlorine dose increased correspondingly decreased the capacity of activated carbon to adsorb 2-MIB and geosmin. Even though previously adsorbed 2-MIB and geosmin released, as result of the application of delaying the chlorine adding was more beneficial than simultaneous adding chlorine with PAC.

• 한국식품과학회지
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• 제35권2호
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• pp.320-324
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• 2003

감마선 조사에 의한 육제품의 색 변화를 최소화하기 위하여 함기, $CO_2, \;N_2$, 및 $CO_2/N_2$ 포장한 후 각 포장환경에 따른 소시지의 NO-Mb 함량 및 CIE color values를 측정하였다. 감마선 조사에 의해 NO-Mb 함량이 다소 감소하여 조사에 의한 denitrosylation이 일어나는 것으로 나타났으며, $CO_2/N_2$ 혹은 $CO_2$ 포장시 저장동안 NO-Mb 함량을 유지하는데 효과적이었다. CIE color values 중 $a^*$값은 감마선 조사 및 포장방법에 의한 유의적인 차이를 보였는데, 5kGy 이상의 감마선 조사시 $a^*$값이 감소하였으며, 함기포장구의 적색도가 낮은 것으로 나타났다. 따라서 $CO_2/N_2,\;CO_2$와 같은 가스치환 포장시 감마선 조사에 의한 육색변화를 억제하는데 효과적인 것으로 나타났다.

• Biomolecules & Therapeutics
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• 제27권6호
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• pp.591-602
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• 2019

Human breast cancer cell line, MDA-MB-231, is highly invasive and aggressive, compared to less invasive cell line, MCF-7. To explore the genes that might influence the malignancy of MDA-MB-231, DNA microarray analysis was performed. The results showed that G0/G1 switch 2 (G0S2) was one of the most highly expressed genes among the genes upregulated in MDA-MB-231. Although G0S2 acts as a direct inhibitor of adipose triglyceride lipase, action of G0S2 in cancer progression is not yet understood. To investigate whether G0S2 affects invasiveness of MDA-MB-231 cells, G0S2 expression was inhibited using siRNA, which led to decreased cell proliferation, migration, and invasion of MDA-MB-231 cells. Consequently, G0S2 inhibition inactivated integrin-regulated FAK-Src signaling, which promoted Hippo signaling and inactivated ERK1/2 signaling. In addition, G0S2 downregulation decreased ${\beta}$-catenin expression, while E-cadherin expression was increased. It was demonstrated for the first time that G0S2 mediates the Hippo pathway and induces epithelial to mesenchymal transition (EMT). Taken together, our results suggest that G0S2 is a major factor contributing to cell survival and metastasis of MDA-MB-231 cells.

• 상하수도학회지
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• 제24권3호
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• pp.307-317
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• 2010

This study was conducted in order to investigate bulk organic matter characteristics and behavior of geosmin and 2-methylisoborneol (2-MIB) during riverbank filtration, which are general surrogates of taste and odor in drinking water. Column studies were used to simulate bank filtration systems. Most of the aliphatic organic matter was removed effectively after soil passage, and it is believed to be polysaccharides according to LC-OCD and F-EEM analysises. Removal efficiencies of geosmin and 2-MIB within the filtration column reached above 95%. It was found that the removal of total dissolved organic matter has a correlation with that of geosmin and 2-MIB in the near of filtration surface (about 50cm).

• Bulletin of the Korean Chemical Society
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• 제34권2호
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• pp.475-481
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• 2013

By using ionic liquid 1-hexylpyridinium hexafluorophosphate ($HPPF_6$) based carbon ionic liquid electrode (CILE) as the substrate electrode, a $CoMoO_4$ nanorods and myoglobin (Mb) composite was casted on the surface of CILE with chitosan (CTS) as the film forming material to obtain the modified electrode (CTS/$CoMoO_4$-Mb/CILE). Spectroscopic results indicated that Mb retained its native structures without any conformational changes after mixed with $CoMoO_4$ nanorods and CTS. Electrochemical behaviors of Mb on the electrode were carefully investigated by cyclic voltammetry with a pair of well-defined redox peaks from the heme Fe(III)/Fe(II) redox center of Mb appeared, which indicated that direct electron transfer between Mb and CILE was realized. Electrochemical parameters such as the electron transfer number (n), charge transfer coefficient (${\alpha}$) and electron transfer rate constant ($k_s$) were estimated by cyclic voltammetry with the results as 1.09, 0.53 and 1.16 $s^{-1}$, respectively. The Mb modified electrode showed good electrocatalytic ability toward the reduction of trichloroacetic acid in the concentration range from 0.1 to 32.0 mmol $L^{-1}$ with the detection limit as 0.036 mmol $L^{-1}$ ($3{\sigma}$), and the reduction of $H_2O_2$ in the concentration range from 0.12 to 397.0 ${\mu}mol\;L^{-1}$ with the detection limit as 0.0426 ${\mu}mol\;L^{-1}$ ($3{\sigma}$).

• 전기전자학회논문지
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• 제26권4호
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• pp.659-670
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• 2022

본 논문에서는 ×32 LPDDR2 메모리를 지원하는 컨트롤러를 위한 830-Mb/s/pin 송수신기가 설계된다. 여덟 개의 단위 회로로 구성된 송신단은 34Ω ∽ 240Ω 범위의 임피던스를 가지고 임피던스 보정 회로에 의해 제어된다. 송신되는 DQS의 신호는 DQ의 신호들 대비 90° 이동된 위상을 가진다. 수신 동작시 read time 보정은 바이트 내에서 per-pin 스큐 보정과 클록-도메인 전환을 통해 수행된다. 구현된 LPDDR2 메모리 컨트롤러를 위한 송수신기는 1.2V 공급 전압을 사용하는 55-nm 공정에서 설계되었으며 830-Mb/s/pin의 신호 전송률을 가진다. 각 lane의 면적과 전력 소모는 각각 0.664 mm²과 22.3 mW이다.

• 대한화학회지
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• 제55권5호
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• pp.746-750
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• 2011

Fluorescence correlation spectroscopy (FCS) is an emerging fluorescence technique used to study the dynamics of proteins on a millisecond to microsecond time scale at the single-molecule level. Solution pH-modulated protein conformational changes can be manifested by binding rate, fluorescence lifetime, and binding specificity of a probe molecule. The fluorescence lifetime of Nile red (NR) bound to apomyoglobin (apoMb) was measured to be $6{\pm}0.3$ ns, much longer than that in water solution ($2.9{\pm}0.2$ ns). As the unfolding population of apoMb increased by lowering pH of solution, the fraction for the longer lifetime of NR decreased with an increasing fraction for the shorter lifetime of NR in water. Unlike 1-anilino-8-naphthalene sulfonic acid, which has many lifetimes due to nonspecific binding to the unfolded apoMb, NR bound to apoMb possesses only a single lifetime. These results suggest that NR binds specifically to native apoMb and thus can be utilized to probe the folding/unfolding dynamics of apoMb using FCS.

• 한국통신학회논문지
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• 제26권12B호
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• pp.1695-1702
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• 2001

본 논문에서는 4 Mb/s 부터 100 Mb/s 의 IrDA(Infrared Data Association) 응용이 가능한 CMOS infrared (IR) wireless data link IC의 설계 방법에 대해 기술한다. 이 모듈은 60 dB에서 100 dB가지의 이득 범위를 가지는 variable gain transimpedance amplifier, AGC(automatic gain control) 회로, AOC(automatic offset control) loop, 4 PPM (pulse position modulation) modulator/demodulator와 DLL(delay locked loops)로 구성된다. 본 적외선 광송수신 IC는 0.25 um 1-poly 5-metal CMOS 공정을 이용하여 제작되었다. 2.5 V 전원 전압에서 동작시켰으며 100 Mb/s에서 출력단 버퍼를 제외하고 25 mW의 진력을 소모한다. 칩의 크기는 1.5 mm $\times$ 1 mm이다.