• Journal of the Microelectronics and Packaging Society
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• v.11 no.2 s.31
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• pp.59-66
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• 2004

This paper presents a novel fabrication process for a tapered hollow metallic microneedle array using backside exposure of SU-8, and analytic solutions of critical buckling of a tapered hollow microneedle. An SU-8 meta was formed on a Pyrex glass substrate and another SU-8 layer, which was spun on top of the SU-8 mesa, was exposed through the backside of the glass substrate. An array of SU-8 tapered pillar structures. with angles in the range of $3.1^{\circ}{\sim}5^{\circ}$ was formed on top of the SU-8 mesa. Conformal electrodeposition of metal was carried out followed by a mechanical polishing using a pianarizing polymeric layer. All organic layers were then removed to create a metallic hollow microneedle array with a fluidic reservoir on the backside. Both $200{\mu}m\;and\;400{\mu}m$ tall, 10 by 10 arrays of metallic microneedles with inner diameters of the tip in the range of $33.6{\sim}101\;{\mu}m$ and wall thickness of $10{\mu}m\;-\;20{\mu}m$ were fabricated. Analytic solutions of the critical buckling of arbitrary-angled truncated cone-shaped columns are also presented. It was found that a single $400{\mu}m$ tall hollow cylindrical microneedle made of electroplated nickel with a wall thickness of $20{\mu}m$, a tapered angle of $3.08^{\circ}$ and a tip inner diameter of $33.6{\mu}m$ has a critical buckling force of 1.8 N. This analytic solution can be used for square or rectangular cross-sectioned column structures with proper modifications.

• Progress in Medical Physics
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• v.22 no.2
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• pp.72-78
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• 2011

The aim of this study is to evaluate the patient's setup errors in TomoTherapy (Hi-Art II, TomoTherapy, USA) Bodyfix system (Medical Intelligence, Ele-kta, Schwabmuchen, Germany) pressure in the vacuum compression, depending on and were evaluated. Bodyfix immobilization system and vacuum pressure was compression applied to the patients who received Tomotherapy thoracic and abdominal area, 21 patients were selected and TomoTehpay treatment total 477 of MVCT images were obtained. The translational (medial-lateral: ML, anterior-posterior: AP, superior-inferior: SI directions) and rolling were recorded and analyzed statistically. Using Pearson's product-moment coefficient and One-way ANOVA, the degree of correlation depending on the different vacuum pressure levels were statistically analyzed for setup errors from five groups (p<0.05). The largest average and standard deviation of systematic errors were 6.00, 5.95 mm in the AP and SI directions, respectively. The largest average of random errors were 4.72 mm in the SI directions. The correlation coefficients were 0.485, 0.244, and 0.637 for the ML-Roll, AP-Vector, and SI-Vector, respectively. SI-Vector direction showed the best relationship. In the results of the different degree of vacuum pressure in five groups (Pressure range: 30~70 mbar), the setup errors between the ML, SI in both directions and Roll p=0.00 (p<0.05) were shown significant differences. The average errors of SI direction in the vacuum pressure of 40 mbar and 70 mbar group were 4.78 mm and -0.74 mm, respectively. In this study, the correlation between the vacuum pressure and the setup-errors were statistically analyzed. The fact that setup-errors in SI direction is dependent in vacuum pressure considerly setup-errors and movement of interal organs was identified. Finally, setup-errors, and it, based on the movement of internal organs in Bodyfix system we should apply more than 50 mbar vacuum pressure. Based on the results of this study, it is suggested that accuracy of the vacuum pressure and the quantitative analysis of movement of internal organs and the tumor should be studied.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.2
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• pp.37.3-38
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• 2017

우리나라의 천문 관측의 기록의 역사는 삼국시대 이전 선사시대까지 거슬러 올라간다. 선사시대에는 천문 현상을 바위나 건축 유물에 기록을 남기고 역사를 기록하기 시작한 이후에는 일반 역사 기록 속에 항상 함께 기록하고 있다. 특히 동양은 역사기록 자체가 인간이 남긴 자취뿐만 아니라 하늘과 땅에 일어나는 다양한 자연 현상도 함께 동시에 남겼다. 고대로부터 인간은 하늘과 땅과 항상 유기적인 관계를 갖는다고 믿었기 때문이다. 우리나라는 정사로서 가장 오래된 역사 기록인 삼국사기와 삼국유사에 일식, 혜성 출현, 별똥과 유성우, 달과 행성 운행, 초신성 관측 등 250회 이상의 천문 기록이 나타나며 대부분 실제로 일어났던 사실을 그대로 기록하고 있다. 그 후 고려사와 조선왕조실록에는 이루 헤아릴 수 없을 정도로 많은 천문 기록을 남기고 있다. 이러한 천문 기록뿐만 아니라 일찍부터 중국으로부터 역법을 도입하여 천체 운행을 이용하여 우리 생활에 필요한 시각법을 사용하고 달력을 제작하였다. 특히 달과 태양의 운행 원리를 파악하여 일식과 월식을 직접 추산하였다. 역법의 운용은 천체 운행의 원리를 이해하고 수학을 발전시키는데 큰 역할을 하였다. 이러한 천문 관측과 정확한 시각 체계를 유지하고 정밀한 역법을 사용하기 위해서는 끊임없이 천체를 정밀하게 관측할 필요성이 있다. 이를 위해 다양한 천문 관측기기를 개발하고 제작하였다. 천문 의기는 천체의 위치를 측정하고 천체의 운행을 이용하여 시각 체계를 유지 관리를 위해 필수불가결한 기기이다. 우리나라 천문학 발달의 네 가지 축인 천문(天文), 역법(曆法), 의상(儀象), 구루(晷漏)등은 조선 초기 세종시대 완성을 보게 되었다. 이는 단일 왕조가 이룬 업적으로 다른 문화권에서 볼 수 없을 정도의 우수한 과학 기술의 유산이다. 특히 칠정산내편과 외편의 완성은 중국의 역법에서 벗어나 독자적인 역법을 완성하려는 시도였다. 이 모든 것은 당시 이를 주도하던 세종대왕의 지도력과 천문학과 수학에 뛰어난 천문학자가 이룩한 업적이다. 그 후 조선 중기로 접어들면서 쇠퇴하다가 임진왜란과 병자호란을 겪으면서 거의 모든 과학기술의 유산이 파괴되거나 유실되었다. 조선 현종 이후에 세종시대의 유산을 복원하려는 노력 중에 중국을 통하여 서양의 천문학을 도입하게 되었다. 중국에 들어와 있던 서양 선교사들이 주도하여 중국의 역법 체계를 바꾸었다. 즉, 일식과 월식의 예측력이 뛰어난 시헌력을 만들어 사용하기 시작했다. 시헌력에는 서양의 대수학과 기하학을 이용한 다양한 수학적 기법이 사용되었다. 조선 후기에 이 시헌력을 익히기 위한 노력을 하는 과정에서 서양의 수학과 기하학을 접하게 되고 새로운 우주 체계를 도입하게 되었다. 특히 서양의 천문도와 지도 제작에 기하학의 투사법이 사용되어 복잡한 대수학적 계산을 단순화시켜 활용하였다. 조선 후기에 전문 수학자뿐만 아니라 많은 유학자들도 서양의 수학과 기하학에 깊은 관심을 갖고 연구하였다. 고천문학 전체를 조망해 볼 때 핵심은 현대의 천체물리학이 아니라 위치천문학이다. 따라서 고천문학을 연구하는데 필수적인 요소가 지구의 자전과 공전 운동에 의해서 일어나는 현상과 세차운동에 의한 효과를 정확하게 이해하고 있어야 한다. 그중에서도 구면천문학과 천체역학에 대한 원리를 알고 있는 상태에서 접근해야 한다. 고천문학의 중심인 천문(天文), 역법(曆法), 의상(儀象), 구루(晷漏) 등의 내용은 이러한 위치천문학이 그 기본 골격을 이루고 있다. 예를 들어 고려사의 천문 현상을 모아 놓은 천문지(天文志)와 일식과 월식 계산 원리가 들어있는 역지(曆志)를 연구하기 위해서는 위치천문학의 기본 개념 없이는 연구하는데 한계가 있다. 인문학을 전공하는 학자가 고천문을 연구하는데 가장 큰 걸림돌이 되는 점이 위치 천문학의 기본 개념 없이 접근하는 것이다. 심지어 조선시대 유학자들조차 저술한 많은 천문 관련 기록을 보면 상당부분 천체 운행 원리를 모르고 혼란스럽게 기록된 내용이 적지 않다. 우리나라 수학사를 연구할 경우 방정식 해법, 보간법, 삼각법, 일반 기하 원리에 대한 것을 연구하는데 큰 문제가 없다. 그러나 천문 현상이나 천문 의기 제작에 사용되는 수학은 천문 현상에 대한 원리를 모르면 접근하기 어렵게 된다. 수학사를 하더라고 기본적인 위치 천문학의 기본개념을 이해하고 있어야 폭 넓은 수학사 연구에 성과를 거둘 수 있다. 의외로 천문 현상 추산을 위해 사용되는 수학이나 기하학 원리가 수학사 연구에 중요한 요소가 된다. 더구나 한문으로 기록된 천문 내용을 한문 해독이 능숙한 학자라 하더라도 내용을 모르고 번역하면 도무지 무슨 내용인지 알아볼 수 없는 경우가 많다. 그래서 한문으로 된 천문 현상 기록이나 역법 관련 기록의 번역 내용 중에 많은 오역을 발견하게 된다. 문제는 한번 오역을 해 놓으면 몇 십 년이고 그대로 그 내용을 무비판적으로 인용하게 되고 사실로서 인정하는 오류를 범하게 된다. 이 때문에 우리 선조들이 남긴 고천문 관련 기록에 관한 이해는 우리 현대 천문학자의 역할이 대단히 크다.

• Journal of Life Science
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• v.18 no.11
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• pp.1532-1537
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• 2008

The purpose of this study was to investigate the effect of different arthroplasty designs on knee kinematic and lower limb muscular activation for up-stair and down-stair movement. 3-D video analysis of whole body and joint kinematics and EMG analysis of quadriceps and hamstrings were conducted. One-way ANOVAs were used for statistical analyses (p=0.05). The single-radius group exhibited more arthroplasty limb quadriceps EMG and hamstring coactivation EMG than the multi-radius group. Single-radius demonstrated more abduction angular displacement and reached peak abduction earlier than the multi-radius arthroplasty limb. The single- radius the percent body fat showed similar values in the Elderly, Single and Multi-radius group among the periods, however Control group was Lowered among the periods. Single-radius group limb also increased the quadriceps muscle activation level to produce more knee extension moment to compensate for the short quadriceps moment arm. Resting metabolic rate was significantly increased in control group in the period of LI. Energy expenditure was extremely increased in all groups except control group among the periods. We can say this is the exercise effects.

• The Journal of the Petrological Society of Korea
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• v.10 no.2
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• pp.121-131
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• 2001

The combination of geological, structural and satellite image studies is used to make an examination of the Miocene eruptive type in the Eoil Basin, SE Korea. The basin subsided by the NW-SE extension due to NNW dextral shearing during the East Sea opening. Based on geological structures as well as lithofacies and ages of the basin-fills, it is divided into the NE subbasin and the SW subbasin which were abundantly filled with basaltic volcanics and marine sediments without volcanic materials, respectively: Syndeposional synclines and anticlines are characteristically developed in the NE subbasin, which amplitudes decrease away from the adjacent normal faults to make them into a homoclinal structure. The thicker lavas as well as the younger agglomerates and lacustrine sediments, which show circular distributions, are distributed around the axial zones of major synclines. The satellite image shows four remarkable circular structures within the NE subbasin. They are located adjacent to and along the normal faults, and they are laid almost exactly on the axial zones of the synclines as well as on the distribution area of the agglomerates and lacustrine sediments. These facts indicate that the basaltic lava effusion were conducted by the normal faults like a kind of fissure-eruption and its activity was more predominant at the sites in where the synclines are developed. More active effusion of lava became a reason for deeper subsidence to make differential subsidence and syndepositional folding adjacent to and along the normal faults. Hence, we suggest that a nested cauldron structure was formed in the NE subbasin of the Eoil Basin, and that the volcanism made the subbasin to be a lava pond and controlled the process of filling and sedimentation in the subbasin.

• Korean Journal of Organic Agriculture
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• v.25 no.4
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• pp.901-916
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• 2017

This study was conducted to evaluate natural plant extracts for methane gas reduction in ruminants. Rumen fluid was collected from cannulated Hanwoo cow ($450{\pm}30kg$) consuming 400 g/kg concentrate and 600 g/kg timothy. The 15 ml of mixture comparing McDougall's buffer and rumen fluid in the ratio 2 to 1, was dispensed anaerobically into 50 ml serum bottles. Rumen fluid contents were collected and in vitro fermentation prepared control (timothy, 300 mg), ginseng, balloon flower, yucca plant, camellia, tea plant and ogapi extracts were added at the level of 5% against 300 mg of timothy as a substrate (v/w) and incubated for 3, 6, 9, 12, 24, 48, and 72 h. In vitro pH values range 6.55~7.41, this range include rumen titration. The dry matter digestibility was not differ between all treatments and control. Total gas emission was significantly higher (p<0.05) in ginseng and balloon flower treatments on 24 h than in control. Carbon dioxide emission was not differ all treatments on 9 h than in control and significantly higher (p<0.05) yucca plant, camellia and tea plant treatments on 12 h than control. Methane emission was not differ all treatments on 6 h than in control. The rumen microbial growth rate was significantly higher (p<0.05) in ginseng, balloon flower on 12 h and significantly higher (p<0.05) in ginseng, yucca plant, tea plant and ogapi treatments on 24 h than in control. Total VFA was significantly higher (p<0.05) in tea plant and ogapi treatments on 12 h than in control and significantly higher (p<0.05) in ginseng, balloon flower treatments on 48 h than in control. Acetic acid was significantly lower (p<0.05) in ginseng and balloon flower treatments on 24 h than in control. Propionic acid was significantly higher (p<0.05) in ginseng and balloon flower treatments on 48 h than in control. As a results, sixth natural plant extracts had no significant effect dry matter digestibility and negative on rumen fermentation, but not effect methane reduction.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.28 no.1
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• pp.27-37
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• 2010

This study tries to illuminate the features and values of the Buddhist temple Palkyung by closely examining the forms, structures, and meanings of Tongdo-palkyung(通度八景) handed down at Tongdosa Temple, the best among Korea's Buddhist temples with its three treasures of Buddha, law of Buddha and Buddhist monks. The findings of this study can be summarized as the following. First of all, it reveals the meaning of the geographical name Yeongchuksan(靈鷲山), located to the west of Tongdosa, and a spectacular sight spread like an eagle's spread wings, as well as its location and spatial features. In particular, the arrangement features of a number of attached hermitages clearly show Yeongchuksan's world as being a temple with buddhist treasures. The multi-layered unfolding and centripetal intention of the scenery can be perceived through the shape of the Sshangryongnongju(雙龍弄珠形), around Tongdosa and the feature of the enclosed landscape encircling the steps of Hyeolcheo(穴處) Geumganggyedan. The substances and components of Tongdopalkyung include sound-based spectacles derived from Beoneumgu(梵音具) creating sounds related to religious rituals to enlighten and redeem mankind, such as Yeongji(影池: a holy pond with shadow reflections), drum sounds, and bell sounds along with physical features like pine trees, Dae(臺), waterfalls, Dongcheon (洞天), and a glow in the sky. On the other hand, Palkyung's geographical arrangements exhibit a circular spatial formation based on the main motif as Buddhist symbolism, beginning with the 'Gukjangsangseokpyo(國長生石標)' awakening the territoriality of Tongdosa and locating the first scene 'Mupunghansong(舞風寒松)' in its introductory area, with the features of water, bridge, pine grove, and Iljumun(gate) to stand for the influx. Six other scenes including 'Anyangdongdae(安養東臺)' are placed in the sacred precincts around Daeungjeon and Geumganggyedan while the glow of sunset at 'Danjoseong' just outside the domain closes the symbolic circular formation of the Tongdopalkyung, which coincides with the development of the Mandala figure symbolizing 'Gusanpalhae(九山八海)' centered in Sumisan(須彌山). What is more, Tongdopalkyung, while excluding primary scenic elements inside the temple, maximizes the domain of the mountain's entrance and the effects of the multi-layered mountain, mountain upon mountain, by intensifying the influx and centripetal qualities. The Tongdopalkyung analysis reveals the antithesis of four-coupled scenes conveying buddhist principles and thoughts on the basis of seasons, directions, space and time to display a narrative structural landscape when viewed from the temple's territoriality. Likewise, the characteristics and porch structures of Tongdopalkyung are tools and language of symbols to both externally strengthen the temple's territoriality and to internally, maximize the desires to the Land of Happiness as well as intensify religious wishes and the Mandala's multi-layered qualities through the meanings of time and space.

• Korean Journal of Environmental Agriculture
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• v.15 no.3
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• pp.372-382
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• 1996

In order to elucidate the relationship between the mobility of heavy metals in soil and their uptake by plants, the soil samples collected from the Mangyeong River area were analyzed for the contents and existing forms of the heavy metals and the correlation between the contents of heavy metals in the soil and those in various parts of rice plants therefrom. The soil samples were collectes from ten sites in the paddy fields in 1982 and 1990, respectively, and the analysis on heavy metals including Cd, Zn, Cu and Pb was performed. The results are as follows: Total contents of heavy metals in the samples of 1990 were higher than those of 1982. The extent of increase was that Cd, Zn, Cu and Pb were 3, 29, 59 and 8% in top soil and 8, 50, 91 and 8% in sub-soil, respectively. The order of increasing ratio was Cu > Zn > Pb > Cd and the variation of Cd content by sequentially different extraction was organically bound > dilute acid-extractable=Fe-Mn oxide bound > exchangeable > residual fractions and the content of Cd with organically bound was $46.62{\sim}48.08$ and $41.18{\sim}50.18%$ of total Cd in top and sub-soil, respectively. The ratios of immobile heavy metals, Cd, Pb, Cu and Zn, bound within an oxide or silicate matrix of Fe-Mn oxide in top-soil were 21.25, 35.98, 74.18 and 82.12%, respectively, and consequently their mobile ratios of exchangeable, dilute acid-extractable and organically bound were more than 17.88%. Those of mobile Cd, Pb, Cu and Zn were 78.25, 64.02, 25.82 and 17.88%, respectively. Except for Pb a correlation between the contents of Cd, Zn, and Cu of exchangeable and dilute acid-extractable in top-soil and those in leaf blade, stem and panicle axis was significant, but was not significant in sub-soil.

• Radiation Oncology Journal
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• v.18 no.2
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• pp.107-113
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• 2000

Purpose : The goal of this study 닌as to improve the accuracy of three-dimensional conformal radiotherapy (3-D CRT) by measuring the treatment setup error and physiological movement of liver based on the analysis of images which were obtained by electronic portal imaging device (EPID). Materials and Methods : For 10 patients with hepatocellular carcinoma, 4-7 portal images were obtained by using EPID during the radiotherapy from each patient daiiy. We analyzed the setup error and physiological movement of liver based on the verification data. We also determined the safety margin of the tumor in 3-D CRT through the analysis of physiological movement. Results : The setup errors were measured as 3mm with standard deviation 1.70 mm in x direction and 3.7 mm with standard deviation 1.88 mm in y direction respectively. Hence, deviation were smaller than 5mm from the center of each axis. The measured range of liver movement due to the physiological motion was 8.63 mm on the average. Considering the motion of liver and setup error, the safety margin of tumor was at least 15 mm. Conclusion : EPID is a very useful device for the determination of the optimal margin of the tumor, and thus enhance the accuracy and stability of the 3-D CRT in patients with hepatocellular carcinoma.

• Radiation Oncology Journal
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• v.18 no.2
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• pp.150-156
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• 2000

Purpose : Stereotactic radiation therapy (SRT) can deliver highly focused radiation to a small and spherical target lesion with very high degree of mechanical accuracy. For non-spherical and large lesions, however, inclusion of the neighboring normal structures within the high dose radiation volume is inevitable in SRT This is to report the beam shaping using the partial closure of the independent jaw in SRT and the verification of dose calculation and the dose display using a home-made soft ware. Materials and Methods : Authors adopted the idea to partially close one or more independent collimator jaw(5) in addition to the circular collimator cones to shield the neighboring normal structures while keeping the target lesion within the radiation beam field at all angles along the arc trajectory. The output factors (OF's) and the tissue-maximum ratios (TMR's) were measured using the micro ion chamber in the water phantom dosimetry system, and were compared with the theoretical calculations. A film dosimetry procedure was peformed to obtain the depth dose profiles at 5 cm, and they were also compared with the theoretical calculations, where the radiation dose would depend on the actual area of irradiation. Authors incorporated this algorithm into the home-made SRT software for the isodose calculation and display, and was tried on an example case with single brain metastasis. The dose-volume histograms (DVH's) of the planning target volume (PTV) and the normal brain derived by the control plan were reciprocally compared with those derived by the plan using the same arc arrangement plus the independent collimator jaw closure. Results : When using 5.0 cm diameter collimator, the measurements of the OF's and the TMR's with one independent jaw set at 30 mm (unblocked), 15.5 mm, 8.6 mm, and 0 mm from th central beam axis showed good correlation to the theoretical calculation within 0.5% and 0.3% error range. The dose profiles at 5 cm depth obtained by the film dosimetry also showed very good correlation to the theoretical calculations. The isodose profiles obtained on the home-made software demonstrated a slightly more conformal dose distribution around the target lesion by using the independent jaw closure, where the DVH's of the PTV were almost equivalent on the two plans, while the DVH's for the normal brain showed that less volume of the normal brain receiving high radiation dose by using this modification than the control plan employing the circular collimator cone only. Conclusions : With the beam shaping modification using the independent jaw closure, authors have realized wider clinical application of SRT with more conformal dose planning. Authors believe that SRT, with beam shaping ideas and efforts, should no longer be limited to the small spherical lesions, but be more widely applied to rather irregularly shaped tumors in the intracranial and the head and neck regions.