• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.1B
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• pp.21-28
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• 2011

The femtocell is a miniaturized Base Station (BS) with low-cost and low-power using general broadband access network as backhaul. It is expected not only to improve indoor coverage but also to reduce a service charge. However, in IEEE 802,16e femtocells, when the Mobile Station (MS) scans neighbor BSs for handover, it takes a long time due to too many number of femto BSs. Also the size of the neighbor advertisement message that will be periodically sent by a serving BS is increased as the number of target femto BSs for scanning increases. In this paper, we proposed an efficient femtocell scanning scheme, using a triangulation mechanism and a femto BS monitoring scheme to reduce the number of scanning operations and the size of the neighbor advertisement messages. The proposed scheme can avoid wasting air resources and reduce scanning overheads by minimal scanning operation. The simulation results showed that the proposed scheme could improve scanning performance and avoid wasting air resources, compared with the conventional scheme of the IEEE 802.16e system.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.6A
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• pp.624-634
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• 2008

The mobile station which is about to do handover in IEEE 802.16e networks scans its neighboring base station channels to decide its next target base station. However, due to the lack of location information of its subscribers, the serving base station cannot provide any reliable candidate channel which is actually attachable by the scanning mobile stations, which makes the mobile station suffer from the long scanning time. Sometimes, long scanning time may cause the degradation of quality of service due to repeatable scan-duration or failure to start the handover procedure in time. To overcome these problems, in this paper, we propose a new protocol so called fast group scanning scheme, in which multiple mobile stations form a group to scan their neighboring base station channels simultaneously. Main contribution of this proposal is to find and decide a reliable target base station within a short scanning time. The fast group scanning scheme can be deployed to the cell network of the serving base station with a dynamic neighboring base station list management.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.3
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• pp.765-771
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• 2005

This study was performed to investigate the anti cancer effect of Batryticatus Bombycis extract(BBE) in B16F10 cells. The cell viability after BBE treatment was quantified by MTT assay. The results showed that BBE inhibited the proliferation of B16F10 cells and caused a 80% inhibition of B16F10 cells at concentration of $500\;{\mu}g/ml$. B16F10 cells exposed to BBE displayed the DNA fragmentation ladder and nucleus chromatin condensation characteristic for apoptosis. The enzyme activity of caspase-3 and actived caspase-3 protein was markedly increased in B16F10 cells treated with the BBE. The expression of Bcl-2, anti-apoptotic protein, was decreased by treatment of the BBE in a dose-dependent manner. And the expression of pro-apoptotic Bax protein was increased. In conclusion, we can suggest that BBE induce the apoptotic death of B16F10 cells via activation of caspase-3, cleavage of PARP protein and Bcl-2 degradation.

• Korean Journal of Microbiology
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• v.51 no.2
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• pp.148-155
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• 2015

The diversity of endobacteria in the edible part (cap and stipe) king oyster mushroom (Pleurotus eryngii) was investigated using 16S rRNA sequence analysis. The bacterial 16S rRNA libraries were constructed from the body cap (BC) and the body stipe (BS) of the king oyster mushroom. The twenty sequenced BC clones were divided into four groups and the largest group was affiliated with the Firmicutes (40% of clones). While, the twenty sequenced BS clones could be divided into six groups and the largest group was affiliated with the Actinobacteria (40% of clones). The predominant bacterial family from both the cap and stipe of the mushroom was corresponded with the Gram positive bacteria (62.5%).

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.12A
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• pp.1226-1237
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• 2007

This paper proposes QoS mesh routing protocol for IEEE 802.16 based wireless mesh networks. QoS mesh routing protocol proposed in this paper is a proactive hop-by-hop QoS routing protocol. The goal of our routing protocol is not only to find a route from a source to a destination, but also optimal route that satisfies QoS requirements, given in terms of bandwidth and delay as default QoS parameters. In this paper, we first analyze possible types of routing protocols that have been studied for MANET and show proactive hop-by-hop routing protocols are the most appropriate for wireless mesh networks. Then, we present a network model for IEEE 802.16 based wireless mesh networks and propose a proactive hop-by-hop QoS routing protocol. Through our simulation, we represent that our routing protocol outperforms QOLSR protocol in terms of end-to-end delay, packet delivery ratio and routing overhead.

• Journal of Digital Contents Society
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• v.6 no.2
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• pp.101-106
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• 2005

In this paper, performance evaluation of mobile access layer for multiple-input multiple-output (MIMO) MultiCarrier(MC)/CDMA 16 QAM system is considered to mitigate multiple access interference and enhance system channel capacity in Rayleigh wireless fading channel. Traditionally, multi-path is viewed as an undesirable feature of wireless communications. Therefore, diversity and adaptive array schemes are proposed to mitigate its effects. Recently, to increase the spectrum efficiency and the link reliability, MIMO schemes is devised to exploit multi-path in a scattering wireless channel. In particular, the channel capacity of MIMO-MC/CDMA 16 QAM system is evaluated according to Eb/No, Mc, p. From the results, in order to improve the channel capacity, the signals at various elements must be uncorrelated. And if the paths are correlated due to inappropriate spacing or mutual coupling effects, the channel capacity of MIMO-MC/CDMA 16 QAM system becomes substantially smaller.

• Journal of Life Science
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• v.23 no.7
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• pp.847-853
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• 2013

The genus Hemerocallis (family Xanthorthoeaceae) is a herbaceous species, some of which are very important in herbal medicines. We evaluated the rps16-trnK region of the chloroplast DNA of a representative sample of eight taxa in Korea to estimate phylogenetic relationships within the taxa of this genus. Due to differences in the number of inserted nucleotides, the aligned data for Hemerocallis ranged from 729 (H. aurantiaca) to 742 nucleotides (H. fulva var. kwanso), with a mean of 736. Although several small indels and 20 inserts were present, sequence variation within the Hemerocallis genus was mostly due to nucleotide substitutions. All rps16-trnK trees generated in Korea exhibited a well-solved topology, with high bootstrap support, irrespective of the methods (parsimony) and the setting used. The node of H. minor and H. littorea was strongly supported, with a high bootstrap value in three trees, and these two taxa were sistered with H. thunbergii. The number of chromosomes was not congruent with that found in a previous study with RAPD, but the number was in agreement with the results of this study.

• Molecules and Cells
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• v.20 no.3
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• pp.378-384
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• 2005

Estrogen metabolites are carcinogenic. The comparative mitogenic activities of $17{\beta}$-estradiol (E2) and four metabolites, 2-hydroxyestradiol (2-OHE2), 4-hydroxyestradiol (4-OHE2), $16{\alpha}$-hydroxyestrone ($16{\alpha}$-OHE1) and 2-methoxyestradiol (2-ME), were determined in estrogen receptor(ER)-positive MCF-7 human breast cancer cells. Each of the E2 metabolites caused proliferation of the MCF-7 cells, but only E2 and $16{\alpha}$-OHE1 induced a greater than 20-fold increases in transcripts of the progesterone receptor (PR) gene, a classical ER-mediated gene. This suggests that the mitogenic action of E2 and $16{\alpha}$-OHE1 could result from their effects on gene expression via the ER. E2 metabolites altered the expression of E2-regulated proteins including heat shock proteins (Hsps). $16{\alpha}$-OHE1 and 2-ME as well as E2 increased levels of Hsp56, Hsp60, $Hsp90{\alpha}$ and Hsp110 transcripts, and the patterns of these inductions resembled that of PR. Hsp56 and Hsp60 protein levels were increased by all the E2 metabolites. Levels of the transcripts of 3 E2-upregulated proteins (XTP3-transactivated protein A, protein disulfide isomerase-associated 4 protein and stathmin 1) and an E2-downregulated protein (aminoacylase 1) were also affected by the E2 metabolites. These results suggest that the altered expression of Hsps (especially Hsp56 and Hsp60) by E2 metabolites such as E2, $16{\alpha}$-OHE1 and 2-ME could be closely linked to their mitogenic action.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.7
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• pp.623-629
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• 2013

This paper presents the implementation result of the EEG(electroencephalogram) signal transmission protocol and its test platform. EEG measured by a dry-type electrode is directly converted into digital signal by ADC(analog-to-digital converter). Thereafter it is transferred DSP(digital signal processor) platform by $I^2C$(inter-integrated circuit) protocol. DSP conducts the pre-processing of EEG and extracts feature vectors of EEG. In this work, we implement the $I^2C$ protocol with 16 channels by using 10 or 12-bit ADC. In the implementation results, the overhead ratio for the 4 bytes data burst transmission measures 2.16 and the total data rates are 345.6 kbps and 414.72 kbps with 10-bit and 12-bit 1 ksps ADC, respectively. Therefore, in order to support a high speed mode of $I^2C$ for 400 kbps, it is required to use 16:1 and $(8:1){\times}2$ ratios for slave:master in 10-bit ADC and 12-bit ADC, respectively.

• Journal of Microbiology and Biotechnology
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• v.26 no.2
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• pp.356-363
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• 2016

Human papillomavirus (HPV), a non-enveloped, double-stranded DNA tumor virus, is a primary etiological agent of cervical cancer development. As a potential tool for prophylactic vaccination, the development of virus-like particles (VLPs) containing the HPV16 L1 capsid protein is highly desired. In this study, we developed a high-level expression system of the HPV16 L1 in Escherichia coli for the purpose of VLP development. The native gene of HPV16 L1 has many rare codons that cause the early termination of translation and result in the production of truncated forms. First, we optimized the codon of the HPV16 L1 gene to the preferable codons of E. coli, and we succeeded in producing the full-size HPV16 L1 protein without early termination. Next, to find the best host for the production of HPV16 L1, we examined a total of eight E. coli strains, and E. coli BL21(DE3) with the highest yield among the strains was selected. With the selected host-vector system, we did a fed-batch cultivation in a lab-scale bioreactor. Two different feeding solutions (complex and defined feeding solutions) were examined and, when the complex feeding solution was used, a 6-fold higher production yield (4.6 g/l) was obtained compared with that with the defined feeding solution.