• IMMUNE NETWORK
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• v.11 no.2
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• pp.100-106
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• 2011

Background: Disparities of Minor H antigens can induce graft rejection after MHC-matched transplantation. H60 has been characterized as a dominant antigen expressed on hematopoietic cells and considered to be an ideal model antigen for study on graft-versus-leukemia effect. Methods: Splenocytes from C57BL/6 mice immunized with H60 congenic splenocytes were used for establishment of H60-specific CTL clones. Then the clones were characterized for proliferation capacity and cytotoxicity after stimulation with H60. Clone #14, #15, and #23 were tested for the TCR binding avidity to H60-peptide/$H-2K^b$ and analyzed for TCR sequences. Results: H60-specific CTL clones showed different levels of proliferation capacity and cytotoxic activity to H60-stimulation. Clones #14, #15, and #23 showed high proliferation activity, high cytotoxicity, and low activities on both aspects, respectively, and have TCRs with different binding avidities to H60-peptide/$H-2K^b$ with $t_{1/2}$ values of 4.87, 6.92, and 13.03 minutes, respectively. The TCR usages were $V{\alpha}12D-3-01+J{\alpha}11-01$ and $V{\beta}12-1-01+D{\beta}1-01+J2-7-01$ for clone #14, $V{\alpha}13D-1-02+J{\alpha}34-02$ and $V{\beta}13-1-02+D{\beta}2-01+J{\beta}2-7-01$ for clone #15, and $V{\alpha}16D+J{\alpha}45-01$ and $V{\beta}12-1-01+D{\beta}1-01+J{\beta}2-5-01$ for clone #23. Conclusion: The results will be useful for modeling GVL and generation TCR transgenic mouse.

• Journal of The Korean Society of Integrative Medicine
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• v.12 no.1
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• pp.73-81
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• 2024

Purpose : The purpose of this study was to identify the degree of occupational therapists' professional identity and examine the correlation between empowerment and burn out. We also investigated the effects of the occupational therapists' professional identity on empowerment and burn out. Through these assessments, we aimed to highlight the importance of professional identity and find methods to improve empowerment and reduce burn out in occupational therapists. Methods : The study was conducted from October 19 to from November 11, 2023. General characteristics, professional identity, empowerment, and burn out were examined using frequency analysis and descriptive statistics. The correlation between these factors was analyzed using Pearson's correlation coefficient. Multiple regression analysis was used to identify factors influencing empowerment and burn out. An α value =.05 was used to verify statistical significance. Results : First, Professional identity was an average 3.24±.37. Second, a significant correlation was found between professional identity and empowerment (r=.417, p<.01) and burn out (r=-.377, p<.01). As a result of the relationship between professional identity sub-factors and empowerment in professional organization (r=.270, p<.01),, belief in self-regulation (r=.258, p<.01), vocational consciousness (r=.348, p<.01), and belief in autonomy (r=.308, p<.01) showed a statistically significant correlation. Professional identity sub-factors were significantly correlated with burnout, professional organization (r=-.199, p<.05), belief in public service (r=-.153, p<.05), belief in self-regulation (r=-.334, p<.01), vocational consciousness (r=-.250, p<.01), and belief in autonomy (r=-.293, p<.01) showed a significant correlation. Third, professional identity sub-factors influencing empowerment were vocational consciousness (β=.154, p<.05) and belief in autonomy (β=.135, p<.05), and those influencing burnout were belief in self-regulation (β=-.389, p<.01) and belief in autonomy (β=-.244, p<.01). Conclusion : The study findings demonstrated that professional identity affects empowerment and burn out. Therefore, continuous study on the professional identity of occupational therapists is warranted.

• Journal of the Korean Dietetic Association
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• v.30 no.1
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• pp.41-60
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• 2024

The number of elderly in care facilities is increasing in parallel with a rapid increase in the elderly population in Korea. We analyzed the meal satisfaction ratings, food preferences, and nutritional intakes of 74 patients aged ≥65 years living in a nursing hospital in Daegu. Food preferences were high for cooked rice, rice gruel, meat soup, soybean paste stew, beef, frozen pollack, squid, egg, spinach, sea mustard, cabbage kimchi, apple, peanut, drinking yogurt, pickled perilla leaves, and salted squid. Preferences for duck (P<0.01) and vegetable (P<0.01) cooking method were significantly different for men and women, and preference for soybean paste stew increased with age (P<0.05). Regarding nutrient intakes, men had higher energy (P<0.01), carbohydrates (P<0.05), and zinc (P<0.05) intakes than women, while women had higher vitamin C (P<0.05) intake than men. Furthermore, energy (P<0.001), carbohydrates (P<0.001), protein (P<0.05), dietary fiber (P<0.01), vitamin B₆ (P<0.01), phosphorus (P<0.05), and zinc (P<0.001) intakes significantly decreased with age. Men had a significantly higher nutrient adequacy ratios (NARs) for carbohydrates (P<0.05) and cal- cium (P<0.01) than women, while women had a significantly higher NARs for protein (P<0.05), vitamin A (P<0.01), vitamin C (P<0.05), thiamine (P<0.01), riboflavin (P<0.001), iron (P<0.001), and zinc (P<0.01). Mean adequacy ratios were 0.69 for men and 0.75 for women. In particular, NARs for carbohydrates (P<0.01), vitamin B₆ (P<0.01), and calcium (P<0.05) decreased significantly with age. In summary, the study shows that supplementing vitamin C, vitamin B₆, calcium, and iron, reducing sodium, and providing meals that reflect preferences will improve the nutritional statuses of elderly residents in a nursing hospital.

• Toxicological Research
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• v.4 no.1
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• pp.55-84
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• 1988

This study was carried out to investigate the teratological potential of azinphos-methyl in the rat fetuses and to establish the nature of the effects on organogenesis and intrauterine development. The Sprague-Dawley female rats (180-210g) without previous litter were used in this study. Azinphos-methyl dosages of 0.094mg/kg, 0.4mg/kg, 1.5mg/kg were selected based on the acute intragastric $LD_{50}$ of 15mg/kg in the rat. Azinphos-methyl in water (Treatment Group), non-treatment control (Negative Control), water control (Sham Control), were administered by oral route and aqueous solution of acetyl salicylic acid (Positive Control) was administered by gavage at rate of 10 ml/kg of body weight from day 6 through 15. The results obtained were summarized as follows. 1. Decreased body weight of dams was observed in animals treated with aspirin and azinphos-methyl 1.5 mg/kg from day 7 through 14. (P<0.01) 2. There was an apparent decrement in the absolute liver weight in the azinphos-methyl 1.5 mg/kg treated group (P<0.05). However, the absolute and relative kidney weight in aspirin group (P<0.05, P<0.01) and the absolute and relative ovary weight in aspirin, azinphos-methyl treatment groups (P<0.01, P<0.05) were increased. 3. Decreased protein contents of dam's liver was observed in the aspirin and high dose azinphos-methyl treated group of animals (P<0.01). 4. The number of male-female ratio per dam increased in azinphos-methyl 1.5 mg/kg group but there was an apparent decrement in the body weight of fetuses in aspirin and high dose azinphos-methyl group (P<0.01, P<0.05). Total immature and resorbed fetuses were increased in aspirin group and the number of dead fetuses were also increased in azinphos-methyl 1.5mg/kg treated group of animals. (P<0.01, P<0.05). 5. In soft tissue defects, diaphragmatic hernia in diaphragm, anophthalmia, enlarged olfactory bulb, hydrocephalus, absence of third and lateral ventricle in skull, hydronephrosis in kidney, atrophy of left ventricle wall, enlarged apex in heart were observed. Especially, defects of diaphragm, heart and eye ball showed peak incidences in the high dose azinphosmethyl and aspirin group. (P<0.01). 6. Variations in the ossification patterns of skull, sternebrae, tail, forelimbs and hindlimbs showed peak incidences in the aspirin and high dose azinphos-methyl group. (P<0.01). 7. In the developmental indices of offspring, the mortality of aspirin and azinphos-methyl 1.5mg/kg treated group was higher than that of negative control. And, there was an apparent decrement in the body weight of fetuses (P<0.01) and considerable differences were obtained in pivoting, development of fur, auditory function, vision, quadrupled muscle development and testes descent in aspirin and azinphos-methyl 1.5mg/kg group. (P<0.01).

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.1
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• pp.132-139
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• 2017

The purpose of this study was to obtain data for contribution of job characteristics (workload, autonomy, reward, community, fairness, and value) to job burnout (emotional exhaustion, and cynicism), and job engagement (vigor, dedication, and absorption) in foodservice dietitians. Our survey was administered to 393 school foodservice dietitians in the Busan area on February 11, 2014. The mean scores of nutrition teachers were significantly higher for autonomy (P<0.01), reward (P<0.05), community (P<0.01), fairness (P<0.001), and value (P<0.001) than unlimited period contract dietitians. The mean scores of high school dietitians were significantly higher for emotional exhaustion (P<0.01) and cynicism (P<0.001) than elementary school dietitians and middle school dietitians. Workload (r=-0.609, P<0.001), reward (r=-0.417, P<0.001), and fairness (r=-0.394, P<0.01) correlated significantly with emotional exhaustion. Reward (r=-0.324) and value (r=-0.423) correlated significantly (P<0.01) with cynicism. Value correlated significantly (P<0.01) with vigor (r=0.493), dedication (r=0.480), and absorption (r=0.460). Workload (${\beta}=-0.521$, P<0.001) had the highest negative influence on emotional exhaustion, whereas value (${\beta}=-0.325$, P<0.001) had the highest negative influence on cynicism. Value had the highest positive influence on vigor (${\beta}=0.392$, P<0.001), dedication (${\beta}=0.443$, P<0.001), and absorption (${\beta}=0.444$, P<0.001). Based on the results of this study, school management should plan job characteristics strategies to reduce workload and increase value for school foodservice dietitians.

• Nuclear Engineering and Technology
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• v.16 no.2
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• pp.58-63
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• 1984

Paper electrophoretic separation of octahedrally bonded (Ruc $l_{6}$ )$^{3-}$ has been carried out by using the specially designed migration apparatus. The supporting electrolyte solutions are as follows: 0.1M-HCl $O_4$, 0.05 M-HCl+0.09M-KCl, 0.1M-HCl, 5$\times$10$^{-3}$ M-NTA, 0.01M-HCl, 0.01M-HCl $O_4$, 0.01M-citric acid, 0.01M-K $H_2$P $O_4$+0.01M-N $a_2$HP $O_4$, 0.05M-borax, 0.025M-N $a_2$C $O_3$+0.025M-NaHC $O_3$, 0.01M-N $a_3$P $O_4$, 0.01M-NaOH and 0.1 M-NaOH. The (Ruc $l_{6}$ )$^{3-}$ appears in 2 to 4 peaks and is found in several chemical species such as (RuCl ($H_2O$)$_{5}$ )$^{2+}$, cis and trans (RuC $l_2$($H_2O$)$_4$)$^{1+}$, (RuC $l_3$($H_2O$)$_3$)$^{0}$ , (RuC $l_4$($H_2O$)$_2$)$^{1-}$, (RuC $l_{5}$ ($H_2O$))$^{2-}$ and (RuC $l_{6}$ )$^{3-}$. The retention value has been found to be highest in the 0.025M-N $a_2$C $O_3$+0.025M-NaHC $O_3$ electrolyte solution.n.

• Journal of the Korea Convergence Society
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• v.8 no.12
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• pp.129-137
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• 2017

The purpose of the study is to investigate the convergence influence of excessive smartphone use on attention deficit, learning environment, and academic procrastination in health college students. A self-reported questionnaire was completed by 255 college students in Busan drom March 6 to June 12, 2017. The degree of smartphone overuse, lack of attention, learning environment, and academic procrastination according to smartphone use characteristics showed significant effects on the time spent on smartphones per day, awareness of smartphone addiction, and personal use of smartphones during class time (p<0.001). It was shown that smartphone overuse was positively correlated with attention deficit (r=0.870, p<0.01), learning environment (r=0.812, p<0.01), academic procrastination (r=0.772, p<0.01), and attention deficit showed a positive relationship with learning environment (r=0.918, p<0.01) and academic procrastination (r=0.798, p<0.01) Learning environment was positively correlated with academic procrastination (r=0.777, p<0.01). The influence factors of smartphone overuse were attention deficit (p<0.001), followed by academic delay behavior (p<0.01). It is necessary to establish a healthy learning environment through prevention and proper use of smartphone.

• Proceedings of the KAIS Fall Conference
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• 2010.11b
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• pp.751-754
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• 2010

본 연구는 초등학교 5, 6학년 학생들을 대상으로 인터넷 게임중독과 자아통제, 충동성과의 관계를 파악하여 올바른 인터넷 사용 문화를 장려하고, 과도한 인터넷 사용 방지교육을 위한 기초자료를 제공하고자 시도되었다. 자료는 2009년 11월 9일에서 11월 30일까지 익산시내 3개 초등학교를 임의로 선정하여 5, 6학년 학생 927명을 대상으로 조사하였다. 자료 분석은 SPSS WIN(12.0 한글판) 프로그램을 이용하여 카이제곱검정, t-검정, 일원배치 분산분석, 다중회귀분석의 통계적 방법을 이용하였다. 본 연구의 결과로는 대상자의 인터넷 게임중독 정도는 '정상' 483명(54.3%), '중독초기' 363명(40.8%), '중독중증' 43명(4.8%)으로 나타났다. 일반적 특성에 따른 인터넷 게임중독 정도를 분석한 결과 성별(p<0.01)이 유의한 차이가 있었으며 컴퓨터 사용 특성에 따른 인터넷 게임중독 정도는 이용장소(p<0.05), 주요활동(p<0.01), 평일 이용시간(p<0.01), 주말 이용시간(p<0.01)이 유의한 차이가 있었다. 또한, 인터넷 게임중독과 자아통제와의 관계를 분석한 결과 인터넷 게임중독 경향이 높을수록 자아통제 점수가 낮으며, 자아통제 점수가 높을수록 인터넷 게임중독 경향이 낮은 것으로 조사되었으며(p<0.01) 인터넷 게임중독과 충동성과의 관계를 분석한 결과 인터넷 게임중독 경향이 높을수록 충동성 점수가 높은 것으로 조사 되었는데, 이는 충동성 점수가 낮을수록 인터넷 게임중독 경향이 낮음을 의미한다(p<0.01). 자아통제와 충동성과의 관계를 분석한 결과 자아통제가 낮을수록 충동성이 높으며, 자아통제가 높을수록 충동성이 낮은 것으로 나타나서 자아통제와 충동성은 서로 반대 개념인 것을 알 수 있었으며(p<0.01) 인터넷 게임중독과 자아통제, 충동성과의 다중회귀분석 결과 유의한 영향을 주는 변수는 성별(p<0.01), 학교성적(p<0.01), 주요활동(p<0.01), 평일 이용시간(p<0.01), 주말 이용시간(p<0.01), 자아통제(p<0.01), 충동성(p<0.01)이었다. 여학생보다 남학생이, 학교성적이 높을수록, 주요활동이 비학습관련인 경우, 평일 이용시간이 1시간이상 이용할수록, 주말 이용시간이 2시간이상 많이 이용할수록, 자아통제가 낮을수록, 충동성이 높을수록, 인터넷 게임중독 경향이 높은 것으로 나타났다. 이상의 결과를 종합해 보면, 인터넷 게임중독 경향이 높을수록 자아통제 정도가 낮게, 충동성 정도는 높게 나타나고, 인터넷 게임중독 경향이 낮을수록 자아통제 정도가 높게, 충동성 정도는 낮게 나타나는 것을 알 수 있다. 또한 자아통제와 충동성은 상반된 개념으로 자아통제 정도가 높을수록 충동성은 낮아지고 자아통제 정도가 낮을수록 충동성이 높아짐을 알 수 있다.

• Food Science of Animal Resources
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• v.27 no.3
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• pp.363-370
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• 2007

In order to identify probiotic microorganisms, 25 isolates of Lactobacillus sp. were selected from kimchi based on their growth rates, lactic acid production and salt tolerance. The isolate JK-01 was identified as Lactobacillus plantarum by the API kit and 16S rDNA analysis (99.9% of homology), and named as L. plantarum JK-01. The maximum number of L. plantarum JK-01 was reached at 18 hr fermentation in MRS broth and the pH gradually decreased to 4.5. L. plantarum JK-01 showed high enzyme activities for xylanase, amylase, protease, and phytase on MRS agar plates containing each substrate. L. plantarum JK-01 showed high resistance to acidic pH and bile salts, and grew well even at pH 2.0 and 1.0% bile salt. In particular, L. plantarum JK-01 showed high heat stability as shown by $3.3{\times}10^3$ CFU/mL at $60^{\circ}C$. The isolate showed remarkable antimicrobial activity against E. coli in MRS broth based on its disappearance after 18 hr and clear zone formation using a paper disk assay. These results suggest that L. plantarum JK-01 may be probiotic in nature.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.5
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• pp.1921-1928
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• 2010

This study was attempted in order to examine about influence of knowledge and attitude toward CPR(Cardiopulmonary Resuscitation) in elementary school students of some regions upon self-confidence. The aim is to be conducive to effective performance and self-confidence in CPR for cardiac arrest patients. We carried out targeting 381 elementary school students who attend 4 schools in J city and K city of J province from June 25 to July 15, 2009. The statistical processing was done by SPSS WIN 12.0 Version. The statistical significance was set to p<.05. As for correlation between variables of cardiopulmonary resuscitation characteristics with knowledge, attitude, and self-confidence, the appearance of acquiring information(r=.174, p<.01), the appearance of experiencing cardiopulmonary resuscitation(r=.143, p<.01), the appearance of educating cardiopulmonary resuscitation(r=.164, p<.01), necessity for education(r=.184, p<.01), knowledge(r=.342, p<.01), and attitude(r=.736, p<.01) showed correlation with self-confidence. As for influence of knowledge and attitude toward cardiopulmonary resuscitation upon self-confidence, the attitude($\beta=.703$, t=17.884, p<.01) had significant influence upon self-confidence. It is necessary to arrange educational program of cardiopulmonary resuscitation, to distribute effective manpower, and to provide elementary school students to cope with emergent situation.