• Korean Journal of Microbiology
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• v.47 no.1
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• pp.1-6
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• 2011

Inefficiency of in vivo gene transfer using currently available vectors reflects a major hurdle in cancer gene therapy. Both viral and non-viral approaches have been described to improve gene transfer efficiency but suffer from a number of limitations. Here we tested an adenovirus carrying the small peptide ligand derived from heregulin${\beta}$ EGF-like domain onto fiber, the adenoviral capsid protein, to deliver transgene to ovarian cancer cells which overexpress ErbB, the cognate receptors for heregulin. The attachement of 53 amino acids to fiber didn't affect on the fiber's trimer structure that is critical for the viral entry to cells. The fiber-modified adenovirus can mediate entry and expression of a ${\beta}$-galactosidase into cancer cells in an increased efficiency compared the unmodified adenovirus. Particularly, the gene transfer efficiency was improved up to 5 times in OVCAR3 cells, an ovarian cancer cell line. Such transduction systems hold promise for delivering genes to ErbB receptor overexpressing cancer cells, and could be used for future cancer gene therapy.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• autumn
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• pp.207-212
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• 2002

The Construction Management(CM) System in Korea is systematized both in name and reality by being prescribed in Construction Industry Act('97) and Construction Management Act('01) through various discussions considering reformation of construction industry structure and enhancement of construction technology competitiveness. Specially in the public construction works, CM Pilot Project is promoted by central government for the activation of CM system introduced for efficiency of public construction project. The promotion of Pilot Project is not only the settlement and activation of CM system but also the process to embody and diversify the CM system. Now we should develop various CM application type such as Owner type, PM type and type for private capital project in doing so. And with this efforts, we could expect that CM system should play an important role to enhance the efficiency of public construction works and should affect private construction sector.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.6
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• pp.1214-1219
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• 2009

Many studies are being applied for various parts of USN (Ubiquitous Sensor Network) technology. The world's large retail stores and warehouses that apply logistic management are also studied. With this, USN technology is increasing in its utilization. However, to handle and process real-time data will never be never easy if these huge warehouses are using too many sensors, and real-time data correction is almost impossible. Software implementation and high-speed hardware are insufficient to solve these complex problems. To solve this problem, a key solution is to implement high-speed software. Hence, this paper suggests a USN logistics management system that applies pipelining techniques for efficiency in real-time data correction and reduces errors of generated values.

• Journal of KIISE:Software and Applications
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• v.29 no.10
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• pp.755-765
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• 2002

In this paper, we observe various syntactic information for Korean parsing and propose a method to learn constraints and improve the efficiency of a parsing model by using the constraints. The proposed method has the following three characteristics. First, it improves the parsing efficiency since we use constraints that can prevent the parser from generating unsuitable candidates. Second, it is robust on a given Korean sentence because the attributes for the constraints are selected based on the syntactic and lexical idiosyncrasy of Korean. Third, it is easy to acquire constraints automatically from a treebank by using a decision tree learning algorithm. The experimental results show that the parser using acquired constraints can reduce the number of overgenerated candidates up to 1/2~1/3 of candidates and it runs 2~3 times faster than the one without any constraints.

• Journal of the Korea Society of Computer and Information
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• v.13 no.6
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• pp.33-39
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• 2008

Energy efficiency should be considered together with performance when designing embedded processors. This paper proposes a new energy-aware instruction cache design using backward branch information to reduce the energy consumption in an embedded processor, since instruction caches consume a significant fraction of the on-chip energy. Proposed instruction cache is composed of two caches: a large main instruction cache and a small loop instruction cache. Proposed technique enables the selective access between the main instruction cache and the loop instruction cache to reduce the number of accesses to the main instruction cache, leading to good energy efficiency. Analysis results show that the proposed instruction cache reduces the energy consumption by 20% on the average, compared to the traditional instruction cache.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.5A
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• pp.549-560
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• 2008

In this paper, we propose a new multi-channel MAC protocol to improve the channel efficiency by using two interfaces. Most of previous researches that have considered multi-channel wireless network environments use a common control channel to exchange control signals and they have a bottle neck problem at common control channel as increasing the number of data channels. In the proposed MAC protocol, we separate receiving and transmitting channels so that sending and receiving data and control packets at the same time is possible. It increases the total network throughput. Since there is no common control channel, the network does not suffer from the bottle neck problem. By applying a TDMA scheme, we can avoid packet collisions between data packets and control packets and reduce the possibility of CTS or ACK packet collisions. Simulation results show that the proposed multi-channel MAC protocol improves the total network throughput and channel efficiency compared with the existing method.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.209-209
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• 2015

상수도 관망은 대표적인 사회기반시설로 수원으로부터 수용가에 이르기까지 안정적으로 유량을 공급하는 것을 목표로 한다. 상수도 관망의 최적설계는 요구되는 절점의 수압, 관로의 유속 등 수리학적 제약조건을 만족시키는 범위 안에서 비용을 최소화하는 설계안을 얻어내는 것을 목표로 시작하였다. 하지만 비용만을 고려한 과거의 상수도 관망 최적설계는 미래의 불확실한 조건에 매우 취약하고, 사용자의 다양한 요구를 충족시키지 못한다. 이 때문에 현대의 상수도 관망의 설계시 다양한 설계인자의 고려와 함께 효율적인 최적설계기법 적용의 필요성이 대두되고 있다. 따라서 본 연구에서는 상수도 관망 최적설계에 다양한 설계인자를 동시에 고려하기 위해 다목적 최적 설계기법인 Multi-objective Harmony Search 알고리즘을 적용하였다. 또한 다목적 최적설계의 효율성 증대를 위하여 매개변수 자동보정 기법 중 하나인 Parameter-Setting-Free (PSF) 기법(Geem and Sim, 2010)을 사용하였다. PSF 기법은 최적화 알고리즘의 매개변수 설정의 번거로움을 없애고, 반복수행을 통한 해 탐색이 진행됨에 따라 가장 효율적으로 작용하는 매개변수를 자동으로 설정하여 탐색효율을 강화하도록 고안된 기법이다. 본 연구에서는 제안된 기법을 실제 상수도관망의 최적설계에 적용하였고 그 결과를 분석하였다. 그 결과 제안된 기법을 통해 관망의 비용을 포함한 다양한 설계인자를 동시에 만족시키는 최적설계안을 효과적으로 도출 할 수 있었으며, 매개변수 자동보정 기법의 적용을 통해 해 탐색의 효율성과 편의성을 향상시킬 수 있었다.

• Journal of the Microelectronics and Packaging Society
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• v.31 no.3
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• pp.99-104
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• 2024

With the advancement of power electronics technology and the increasing demand for high-efficiency power semiconductors, silicon carbide (SiC) devices have gained attention as an alternative to overcome the limitations of traditional silicon (Si) semiconductors. SiC devices enable excellent switching efficiency due to their high switching speed. However, parasitic inductance within the power module can cause voltage oscillations and overshoot phenomena, potentially leading to issues with electrical reliability and efficiency. To address these challenges, two approaches were proposed and validated. The first approach involved applying an RC snubber circuit to mitigate the effects of parasitic inductance, thereby improving electrical stability. The second approach focused on optimizing the lead-frame design to reduce parasitic inductance. Both methods were verified through simulations and experiments, demonstrating that the electrical reliability and efficiency of SiC power modules can be simultaneously improved.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.2
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• pp.749-755
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• 2013

The public corporations have already implemented ERP to improve productivity, quality, and cost saving. This paper presents the result of business process improvement based on implementation of ERP. Therefore, this paper performed case study of K corporation. Survey was conducted to define the degree of improvement and evaluation method was presented using AHP. The weights for each business area is assigned based on AHP. Then ERP is evaluated in efficiency, work transparency, information sharability, and easy of use. It is meaningful achievement considering its short term implementation. The human resource management shows a relatively larger improvement than other management processes. However, information sharability shows relatively low improvement than others. This quantified result of user-oriented subjective evaluation on ERP implementation will contribute to evaluate the impact of ERP for owner organizations.

• Journal of the Korea Convergence Society
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• v.10 no.11
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• pp.275-282
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• 2019

Social Skills are one of the most important competency for student who live in the future Society. The purpose of this study is to propose a Forum Theatre Instruction utilizing smart devices as an alternative teaching and learning methods for enhancing the social skills of students, and to examine the effect of this instruction on the improvement of it. In order to achieve the purpose, the class was designed based on the 'Procedural Instructional Model for FTI using Digital Media', and the effectiveness of it was verified using 'SSIS'. FTI can be composed of six classes, and results of paired t-test showed that it was effective in enhancing students' social skills. Reflecting the interview results of the participant, the further requirements for improvement and efficient use of FTI were suggested.