• Korean Journal of Plant Resources
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• v.27 no.4
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• pp.271-278
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• 2014

Rubus coreanus has been used as a traditional medicine in Asia because of its various pharmacological properties. This study examined the effects of protocatechuic acid (PCA), one of phenolic compounds derived from R. coreanus on the lipid metabolism in high cholesterol diet-induced mice. A total of 30 male C57BL/6 mice were divided into 5 groups with 6 mice in each group as follows: (1) Control mice received normal diet (ND). (2) Mice received high-cholesterol diet (HCD) plus water, 10% sucrose solution and treated daily oral phosphate-buffered-saline (PBS) of equal volumes through gavage. (3) Mice received HCD and treated daily with 25 mg/kg b.w./day of PCA (4) with 50 mg/kg b.w./day or (5) with 10 mg/kg b.w./day of simvastatin via oral gavage for 12 weeks. Body weights were measured weekly for a period of experiment. After treatment, liver, thymus, spleen and kidney were harvested and weighed, and the lipid metabolite profiles (total cholesterol, triglyceride (TG), HDL-cholesterol (HDL-c), LDL-cholesterol (LDL-c) and liver-damaging markers (GOT and GPT) in serum were examined. PCA significantly reduced the total cholesterol, TG, LDL-c level and increased the HDL-c level. PCA administration also significantly reduced the levels of GOT and GPT. These results indicate that the PCA could be used as a functional material for lowering lipid and an adjuvant for the treatment of hyperlipemia.

• The Korean Journal of Malacology
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• v.19 no.1
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• pp.71-79
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• 2003

After the juvenile octopus individuals being discharged, it is hard to separately capture them because they attach strongly to the wall of the aquarium by the suckers on the arms. Therefore, anaesthetics (MS-222 or lidocaine-HCl) are usually used for capture from attachment. The anaesthetized time of the octopus by lidocaine-HCl was more faster 1.6 to 4.5 times under 200 ppm and 6.0 to 6.5 times in 300 to 500 ppm than those in MS-222. In the anaesthetized and recovery rates (%) by the exposed time, the juvenile octopuses were anesthetized by lower concentrations of lidocaine-HCl within the short time, and rapidly recovered from anesthesia. In the secondary anesthesia of the juvenile octopuses exposed with lidocaine-HCl by the elapsed time after the primary anesthesia, the anesthetized time was later in case of lower concentrations and long elapsed times, However, the anesthetized time was faster when their concentrations were higher and the elapsed time after anesthesia were shorter. Recovery from the secondary anesthesia was faster when the elapsed time was long in lower concentration, and was later when the elapsed time was shorter. In case of Octopus ocellatus, anaesthetic effects by lidocaine-HCl concentrations were better than those of MS-222. Doses of lidocaine-HCl and critical time for works at the indoor laboratory were proper in concentration of 100 ppm within 15 min.

• Korean Journal of Food Science and Technology
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• v.38 no.5
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• pp.720-723
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• 2006

The viability of Shigella sonnei, a significant cause of gastroenteritis in Korea, on TSA plates was determined after sublethal heating treatments and NaCl treatments. In addition, recovery levels of sublethally injured cells on TSA plates containing different concentrations of NaCl (TSAS) were investigated. The viability decreased significantly with increasing degree of sublethal heating treatments, but increases in NaCI treatment concentration from 0 to 6% had little effect on the viability. After being sublethally treated at $55^{\circ}C$ for 30 min, bacterial populations were reduced by 7.58, 7.83 and 7.93 log CFU/mL on 2, 4, and 6% TSAS, respectively. After being sublethally treated at $60^{\circ}C$ for 30 min, bacterial populations were reduced by 6.71, 6.73, and 6.73 log CFU/mL on 2, 4 and 6% TSAS, respectively. Decimal reduction times (D-values) decreased with increasing NaCl treatment concentrations after sublethal heating at 55 or $60^{\circ}C$. These data imply that the S. sonnei cells sublethally injured by insufficient heating processes had a lower recovery rate with increasing NaCl concentrations in the recovery media.

• Membrane Journal
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• v.22 no.6
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• pp.461-469
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• 2012

This study was carried out to find the optimum chemical cleaning (CIP) conditions for ceramic microfiltration membrane process of Y drinking water treatment plant. B train consists of coagulation as pretreatment process with membrane was chemically cleaned 9 times more than that of A train with ozonation and coagulation. The frequent CIP of B train was due to improper CIP method suggested by membrane manufacture as well as different membrane fouling between A and B train resulting from the different pretreatment processes. That is, recovery rate of CIP was overestimated because the rate was calculated based on normalized trans membrane pressure (TMP) rather than normalized permeability. And also, iron oxide fouling was ineffectively removed by citric acid. By using a mixture of 1% citric acid and 0.1 N sulfuric acid as reagent for acid CIP step, the recovery rate of CIP was the highest while CIP efficiency by 0.1 N sulfuric acid was the lowest. When sulfuric acid concentration increased from 0.1 N to 0.3 N in mixture, total recovery rate of CIP was not increased due to the decreased CIP efficiency in alkali CIP step by 0.3% NaOCl although its rate in acid CIP step was increased. It was proved through the experiment result of CIP sequence changes that an acid followed by alkali CIP was more effective than that of the reverse method.

• Journal of Oral Medicine and Pain
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• v.32 no.3
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• pp.337-346
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• 2007

This study aimed to evaluate a relation of bruxism with clinical effects of botulinum toxin type A(BTX-A) injection. 5 bruxers and 5 nonbruxers with bilateral masseter hypertrophy were participated in this study. After injecting 25 unit of BTX-A(Allergen Inc, $Botox^{(R)}$) into each masseter muscle, the thickness of masseter(Mm) and anterior temporalis(Ta) muscles was measured by ultrasonography and the maximum bite force was evaluated during a 9-month period. Self-estimation on the recovery of occlusal force during mastication was done as well. Regardless of presence of bruxsim, all subjects showed significantly reduced Ms thickness(p<0.001) and maximum bite force at $1^{st}$ molars(p=0.027) with their peak at 3 months after injection, which then started to return. No significant difference was observed in Ta thickness and the bite force at the central incisors. While self-estimated occlusal force was the least at 2 weeks after injection and then rapidly returned to the baseline level with full recovery at the time of 6 to 9 months after injection, the maximum bite force measured by bite force recorder did not recover the original value, particularly in the nonbruxer group. It is assumed that nocturnal bruxism can influence recovery of atrophic masseter and decreased occlusal force due to BTX-A injection. These findings suggest a need of occlusal appliance to control bruxism or clenching habit for longer clinical effect of BTX-A injection.

• Membrane Journal
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• v.26 no.4
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• pp.273-280
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• 2016

Pressure assisted forward osmosis (PAFO) is recently introduced because of its improved process efficiency to overcome drawbacks of forward osmosis (FO) such as low water flux and reverse solute diffusion. However, it is known that membrane fouling becomes deteriorated by additional hydraulic pressure applied in PAFO compared to FO. This study was performed to investigate possibility of intermittent pressure-assisted forward osmosis (I-PAFO) operation for fouling mitigation using colloidal silica particles as model foulants. FO, PAFO were operated as well to compare with. Two different solution pH conditions (pH 3, 10) were applied to see the effect of electrostatic interactions between the membrane and silica particles on fouling tendency. In the results, higher water flux was observed during pressurization and pressure relaxation periods in I-PAFO than water flux of PAFO, and FO on both pH conditions. Water flux decreased less in I-PAFO than PAFO after fouling. It resulted in higher water flux recovery in I-PAFO than PAFO after physical cleaning.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2006.05a
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• pp.49-56
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• 2006

최근 제조업을 보완하는 새로운 성장동력으로 서비스산업의 중요성이 부각되고 있다. 특히 무선 인터넷과 통신 기술의 발전은 신 서비스 창출의 기회를 마련해주는 동시에 서비스 시스템을 복잡하게 변화시키고 있다. 그러나 기존의 서비스 개발은 정성적인 판단과 직관에 의지하고 있으며, 서비스 개발 방법론은 개념적이고 추상적인 수준에서 제공되고 있다는 한계를 가진다. 이는 모바일 비즈니스(mobile business)와 같은 복잡한 서비스 시스템의 변화에 능동적으로 대처하지 못하고 있어, 모바일 비즈니스를 위한 실질적이고 체계적인 신 서비스 개발의 방법론의 필요성을 증가시킨다. 본 연구에서는 morphology 분석을 통해 모바일 비즈니스를 위한 체계적인 신서비스 개발 방법론을 제안한다. 특히 새로운 무선 통신 환경아래에서 급격한 변화를 맞고 있는 음악 산업을 대상으로 제안된 방법론의 활용 사례를 제시할 것이다. 제안된 방법론은 크게 4 단계로 구성된다. 첫째, 제공되는 서비스 시스템을 체계화하기 위해 morphology의 dimension들을 정의한다. 각 차원은 서비스 시스템의 하위 시스템이며, 이는 기존의 문헌조사와 연구를 통해 정의된다. 둘째, 각 차원별로 morphology의 shape를 정의한다. 셋째, 각 차원의 shape를 조합하여 과거의 서비스 시스템을 표현하고, morphology의 dimension과 shape를 확장한다. 넷째, morphology의 확장된 dimension과 shape를 조합하여 새로운 서비스를 구성한다. 제안된 접근법은 크게 두 가지 측면에서 강점을 가진다. 첫째, 신 서비스 아이디어의 획득을 용이하게 할 수 있다. morphology분석은 체계적인 설계 방법론을 창의적인 생각을 돕는 도구로 의미가 있다. 둘째, 체계적인 신 서비스의 개발을 가능하게 한다. morphology접근법은 M-비즈니스와 같은 복잡한 서비스 시스템을 구조적으로 분석하고, 개발할 수 있는 기틀이 된다.킹 대상을 도출할 때까지 추가적인 분석과정을 반복한다. 제안한 방법을 통하여 조직은 기술적 생산 가능성 외에도 다양한 조직 운영 관점에서 적절한 벤치마킹 대상을 선정할 수 있으며, 이에 따른 목표를 수립할 수 있을 것으로 기대한다. 또한 더 나아가 global efficiency 관점에서 효율적 조직이 되기 위하여 단계적인 벤치마킹 대상 선정과 이에 따른 목표를 수립하는데도 유용하리라 판단된다.$1.20{\pm}0.37L$, 72시간에 $1.33{\pm}0.33L$로 유의한 차이를 보였으므로(F=6.153, P=0.004), 술 후 폐환기능 회복에 효과가 있다. 4) 실험군과 대조군의 수술 후 노력성 폐활량은 수술 후 72시간에서 실험군이 $1.90{\pm}0.61L$, 대조군이 $1.51{\pm}0.38L$로 유의한 차이를 보였다(t=2.620, P=0.013). 5) 실험군과 대조군의 수술 후 일초 노력성 호기량은 수술 후 24시간에서 $1.33{\pm}0.56L,\;1.00{\ge}0.28L$로 유의한 차이를 보였고(t=2.530, P=0.017), 술 후 72시간에서 $1.72{\pm}0.65L,\;1.33{\pm}0.3L$로 유의한 차이를 보였다(t=2.540, P=0.016). 6) 대상자의 술 후 폐환기능에 영향을 미치는 요인은 성별로 나타났다. 이에 따른 폐환기능의 차이를 보면, 실험군의 술 후 노력성 폐활량이 48시간에 남자($1.78{\pm}0.61L$)가 여자($1.27{\pm}0.45L$)보다 더 높게 나타났으며 (t=2.170, P=0.042), 72시간에도 역시 남자($2.16{\pm}0.56L$)가 여자($1.50{\pm}0.47L$)보다 더 높았다(t=2.910, P=0.008). 술 후 일초 노

• Journal of KIISE:Computing Practices and Letters
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• v.14 no.8
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• pp.813-817
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• 2008

Intelligent Robots (IR) get data of the current situation from sensors and perform knowledgeable services. Self-reconfiguration of IR is an important factor to change itself without stopping while supporting environment and technology change. In this paper, we propose an agent based self-reconfiguration framework of IR using ESB (Enterprise Service Bus). This framework focuses on dynamic discovery and reconfiguration of service-oriented applications using multi-agent system in intelligent robots. When IR meets an irresolvable situation it downloads a necessary service agent from an external service repository, executes the agent, and resolves the situation. Agent technology provides an intelligent approach for collaborations of IR. The prototype has also been implemented to show the validity of our study.

• The Journal of the Korea Contents Association
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• v.8 no.3
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• pp.197-204
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• 2008

Mass communication leads and the news against the fall of police authority there is a possibility of coming in contact very easily. The police protects the freedom and a right of the citizen, crime prevention and suppresses, maintains a social order, it is a national institution damaging activity. It will be able to hinder the safety of citizen that the fall of police authority. In accordance with in studies are check up point that the post-modernism about fall of police authority and police authority raising plan.

• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.1594-1598
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• 2008

자연하천에서의 형상은 직류하천보다는 어느 정도 만곡이 있는 사행하천이다. 이러한 만곡부가 교호적으로 나타나는 사행하천의 흐름구조는 매우 복잡하며, 이차류가 발생하는 만곡부에서 직류하천에서 예상되는 흐름분포를 왜곡시킴으로써, 유사의 이동, 횡방향의 유속분포가 다르게 나타난다. 이러한 만곡부의 흐름 특성은 만곡부 외측에 측방세굴과 수면교란, 그리고 수위를 상승시키며, 에너지 손실을 가져온다. 일반적으로 사행하천의 만곡부 외측에는 소(pool)가 발달되고, 내측에는 이차류에 의해 강턱 퇴적을 유발함으로써 점 사주(point bar)가 형성된다(우효섭, 2001). 본 연구에서는 사행하천이 비교적 발달한 섬진강 상류 덕치지구 구간에 대하여 2차원 수치모형인 RMA-2 모형을 이용하여 만곡부의 흐름특성을 분석하였다. 분석한 결과 유속의 분포는 만곡부 상류부에서 최대 흐름의 구역이 나타났으며, 만곡부에서는 흐름의 편향구역과 정체구역, 그리고 만곡부 하류부에서 에너지 손실이 일어난 후 흐름의 회복구역으로 흐름의 특성을 나타났다. 또한 수위의 분포는 상류부에서 점차적으로 수위가 감소하다가 만곡부에서 수위가 상승하였고 만곡부가 끝나는 하류부에서의 수위는 감소하였다. 만곡부에서의 횡적인 수위 분포는 만곡부의 외측이 내측보다 수위가 상승되는 것으로 나타났다. 본 연구에서 2차원 수치모형인 RMA-2 모형을 이용한 만곡부의 흐름 특성은 만곡부에서의 홍수위 상승에 대한 검토로서 하천의 바람직한 치수관리 방안에 효과적으로 이용될 수 있을 것으로 판단된다.