• Tuberculosis and Respiratory Diseases
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• v.45 no.4
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• pp.813-822
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• 1998

Background: Extubation is recommended to be performed at minimum pressure support (PSmin) during the pressure support ventilation (PSV). In field, physicians sometimes perform additional 1 hr T-piece trial to the patient at PSmin to reduce re-intubation risk. Although it provides confirmation of patient's breathing reserve, weaning could be delayed due to increased airway resistance by endotracheal tube. Methods: To investigate the effect of additional 1 hr T-piece trial on weaning outcome, a prospective study was done in consecutive 44 patients who had received mechanical ventilation more than 3 days. Respiratory mechanics, hemodymic, and gas exchange measurements were done and the level of PSmin was calculated using the equation (PSmin=peak inspiratory flow rate $\times$ total ventilatory system resistance) at the 15cm $H_2O$ of pressure support. At PSmin, the patients were randomized into intervention (additional 1 hr T-piece trial) and control (extubation at PSmin). The measurements were repeated at PSmm, during weaning process (in cases of intervention), and after extubation. The weaning success was defined as spontaneous breathing more than 48hr after extubation. In intervention group, failure to continue weaning process was also considered as weaning failure. Results: Thirty-six patients with 42 times weaning trial were satisfied to the protocol. Mean PSmin level was 7.6 (${\pm}1.9$)cm $H_2O$. There were no differences in total ventilation times (TVT), APACHE III score, nutritional indices, and respiratory mechanics at PSmin between 2 groups. The weaning success rate and re-intubation rate were not different between intervention group (55% and 18% in each) and control group (70% and 20% in each) at first weaning trial. Work of breathing, pressure time product, and tidal volume were aggravated during 1 hr T-piece trial compared to those of PSmin in intervention group ($10.4{\pm}1.25$ and $1.66{\pm}1.08$ J/L in work of breathing) ($191{\pm}232$ and $287{\pm}217$cm $H_2O$ s/m in pressure time product) ($0.33{\pm}0.09$ and $0.29{\pm}0.09$ L in tidal volume) (P<0.05 in each). As in whole, TVT, and tidal volume at PSmin were significantly different between the patients with weaning success ($246{\pm}195$ hr, $0.43{\pm}0.11$ L) and the those with weaning failure ($407{\pm}248$ hr, $0.35{\pm}0.10$L) (P<0.05 in each). Conclusion : There were no advantage to weaning outcome by addition of 1 hr T-piece trial compared to prompt extubation to the patient at PS min.

• Tuberculosis and Respiratory Diseases
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• v.45 no.5
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• pp.1000-1011
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• 1998

Background: For the diagnosis or evaluation of airway obstruction in bronchial asthma and chronic obstructive lung disorders, various parameters derived from the forced expiratory volume curve and maximal expiratory flow volume curve have been used. Recently the peak expiratory flow(PEF) measured by the peak flow meter is widely used because of its simplicity and convenience. But there were still no data of the predicted normal values measured by the peak flow meter in Korea. This study was to obtain the predicted normal value of PEF and to know the accuracy of this value to predict $FEV_1$. Method: The measurements of PEF by the MiniWright peak flow meter and several parameters derived from the forced expiratory volume and maximal expiratory flow volume curves by the Microspiro HI 501(Chest Co.) were done in 129 men and 125 women without previous history of the respiratory diseases. The predicted normal values of parameters according to the age and the height were obtained, and the regression equation of $FEV_1$ by PEF was calculated. Results: The predicted normal values of PEF(L/min) were -2.45$\times$Age(year) +1.36 $\times$ Height(cm)+427 in men, and -0.96 $\times$ Age (year) + 2.01 $\times$ Height (cm) + 129 in women. FEFmax derived from the maximal expiratory flow volume curve was less than by 125 L/min in men and 118 L/min in women respectively compared to PEF. $FEV_1$(ml) predicted by PEF was 5.98 $\times$ PEF(L/min) + 303 in men, and 4.61 $\times$ PEF(L/min) + 291 in women respectively. Conclusion : The predicted normal value of PEF measured by the peak flow meter was calculated and it could be used as a standard value of PEF while taking care of patients with airway obstruction. $FEV_1$, the gold standard of ventilatory function, could be predicted by PEF to a certain extent.

• Journal of Yeungnam Medical Science
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• v.5 no.1
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• pp.105-110
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• 1988

The study was undertaken to determine the most adequate tidal volume when used volume preset ventilator during anesthesia. The thirty patients were received controlled mechanical ventilation with constant inspiratory pressure of 10cmH2O and respiratory frequency of 12/minute. The results were as follows : 1) The PH was $7.39{\pm}0.01$ and it is within normal limit. 2) The $PaCO_2$ was $34.0{\pm}0.6$ mmHg and it is a slightly hyperventilatory state. 3) The $PaO_2$ was $228.0{\pm}8.2$ mmHg. 4) The Buffer base was $20.7{\pm}0.3mEql$ and it is a slightly buffer base deficient state. From the above results. We concluded that if patients were fully relaxed during general anesthesia, it is desirable to maintain the inspiratory pressure of anesthetic mechanical ventilator to $10cmH_2O$ for adeguate alveolar ventilation.

• Korean Journal of Health Education and Promotion
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• v.12 no.1
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• pp.151-164
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• 1995

한국보건사회연구원의 조사결과에 의하면 이상적인 성비는 1960년의 160에서 1991년에는 130으로 크게 낮아졌다. 아직도 한국 부인들의 이상자녀수는 여아보다 남아가 더 많게 나타나고 있다. 남아의 가치에 대해서는 1960년대에는 노후봉양이 가장 으뜸가는 변수였으나, 최근에는 가계계승보다도 그 중요도가 떨어지고 있는 경향을 보이고 있다. 또한 정서적 유대, 즉 아들이 있어야 든든하다는 식의 주장이 보다 강한 이유로 지적되고 있다. 이러한 남아선호사상은 사회적으로 상당한 영향을 미치는 요인이 되고 있다. 즉 성비의 불균형과 장래의 결혼시장의 혼란이 초래된다는 문제가 그것이다. 예를 들면 현재 셋째 및 넷째 아이의 성비가 크게 상승하고 있는 문제이다. 즉, 1992년의 경우 첫째 아이의 출생성비는 여아 100명당 남아 196.5이고, 넷째 아이의 경우는 229.0으로 더욱 높게 나타났다. 그리고 2000년에는 결혼적령의 남녀 성비의 차이는 신부보다 신랑이 19.1%나 많아질 것이며, 이러한 차이는 2010년에 가면 더욱 심화되어 신부감보다 신랑감이 무려 28.6%가 초과될 전망이다. 가뜩이나 농촌 총각들이 장가 들기가 어려운 터에 장가 못갈 총각이 크게 늘어날 수 밖에 없는 사정이 된다면 사회적으로 큰 혼란이 야기될 것임에 틀림없다. 이러한 성비의 불균형이 초래되는 배경은 남아선호사상의 잔존으로 저출산 내에서 태아의 성을 감별함으로써 선택적인 인공유산을 하는데서 비롯되는 것으로 볼 수 있다. 따라서 현재에도 불식되지 않고 있는 남아선호사상에 대한 주의를 다시 한번 환기시켜야 할 것이다. 특히 이 분야의 보다 깊은 연구를 지속적으로 실시하여 대응전략의 제시에 노력해야 할 것이며, 우선 무엇보다도 여성들의 사회적 지위향상 등 여권신장에 관한 정책적 노력과 더불어 교육 홍보를 통한 노력이 강화되어야 할 것이다. 아울러 태아의 성감별 등 바람직하지 못한 의술남용 행위 등을 근절토록 보다 강력한 법적 적용에도 행정력을 집중시켜 나가야 할 것이다.

• Journal of Bio-Environment Control
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• v.1 no.1
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• pp.72-83
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• 1992

우리 나라 축사는 생산효율 제고를 위하여 대형화, 밀폐화, 고밀도화, 자동화 경향이 뚜렷하다. 대형의 밀폐된 고밀도 축사는 쾌적한 실내환경을 전제로 하기 때문에 기계적으로 실내환경을 적절히 제어하지 않으면 안된다. 제한된 공간에 먼지, 병원성 미생물, 유해기체, 수분이나 열의 과도한 집적은 생산과 재생산효율에 심각한 영향을 미친다. 그러므로 축사내 생산주체인 가축과 작업인이 쾌적한 실내환경에서 생산활동을 할 수 있도록 열적, 화학적/생물학적 환경을 물리적으로 제어하지 않으면 안된다. 본 연구는 실험축사내 가축이 일정한 열을 발생할 때 실내공기의 유동형태를 예측하기 위해서 수행하였다. 이 연구의 결과를 실내환경제어를 위한 환기시스템 책략 개발의 기초자료로 활용할 수 있다. 실험축사내의 공기유동을 예측하기 위해 Body-Fitted Coordinate(BFC)의 격자배열과 k-$\varepsilon$ 난류모형 및 SIMPLE계열 solution scheme을 사용하였으며, 예측의 유효성 검정은 Boon(1978)의 실험결과를 이용하였다. 예측한 공기유동의 형태와 실험한 공기유동의 형태를 비교한 결과 대체로 만족할만한 결과를 얻었다. 그러나 유입공기의 온도가 1$0^{\circ}C$인 경우의 공기유동은 실험유동형태와 약간의 차이가 있었다. 즉, 실험에서는 수평슬롯으로 유입 된 공기가 바로 아래로 굴절되어 유동하였으나, 예측의 결과는 일정 거리로 수평방향으로 유동하다가 아래로 굴절하였다. 이런 유동의 차이는 k-$\varepsilon$ 난류모형 자체가 경험적으로 부력에 민감하게 반응않는 결함이 원인이 될 수도 있으며, 실험의 부적절한 수행이 원인이 될 수도 있다. 이 유동의 경우 Reynolds 수가 3,000정도의 난류이며, 완전발달유동 (fully-developed flow)이므로 관성력 (inertia force)이 부력 (buoyancy force)보다 커, 일정거리 수평으로 유동하다가 아래로 굴절할 수도 있기 때문이다. 앞으로 이를 규명하기 위한 보다 깊이 있는 연구가 이루어져야 할 것이다.

• Journal of Korean Tunnelling and Underground Space Association
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• v.11 no.4
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• pp.387-394
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• 2009

The objective of this study is to evaluate the durability and deterioration of concrete lining in the seven conventional tunnels. These tunnels were constructed about 40~70 years ago, and closed about 10~40 years ago. The field investigation and various laboratory testings were performed for this study. It was observed from the visual, examinations that the concrete linings of 7 tunnels were severely deteriorated, such as, cracks, leakages, desquamation, and exploitations. The compressive strengths obtained from rebound hardness method and uniaxial compressive strength test on core specimens largely differed depending on the locations in the tunnel. The maximum compressive strength of concrete lining was greater about 2 times than the minimum compressive strength of concrete lining in the same tunnel. The results of micro-structural analysis showed that the substances deteriorating the concrete lining, such as ettringite and thaumasite, were detected in the concrete lining of tunnel.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2022.09a
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• pp.117-117
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• 2022

표고(Lentinula edodes (Berk.))는 담자균강 주름버섯목 느타리과 잣버섯속에 속하는 식용버섯으로 봄에서 가을에 걸쳐 주로 재배하며, 예부터 식용 및 약용으로 널리 이용되어져 왔다. 우리나라를 비롯하여 일본, 중국 등의 동남아시아 지역뿐만 아니라 최근에는 미국, 캐나다 및 네덜란드 등의 서구 나라에서도 관심이 높으며, 전 세계적으로 중요한 식용 버섯으로써 주목을 받고 있다. 표고는 혈중 콜레스테롤 수준의 감소, 항당뇨, 혈압조절, 면역증강, 간 보호 및 비만 억제 등의 다양한 생리활성이 밝혀져 있어 현대인의 식생활에서 수요가 더욱 증가되고 있는 추세에 있다. 버섯의 생육은 크게 균사의 생장과 자실체의 생육으로 구분되는데, 표고 균사의 배양 기간이 86~123일 정도 소요되며, 자실체의 생육 기간은 10~20일 정도로, 균사의 배양 기간이 훨씬 긴 것으로 나타났다. 버섯의 생육 단계에서 영양, 생식, 생장은 모두 수분으로부터 비롯되며, 생육 조건, 조도, 환기 정도 등에 따라 버섯의 품질은 상당한 차이를 보일 수 있다. 일반적으로 봄에 수확한 표고는 대가 짧고 단단하며 감칠맛이 풍부하며, 가을에 수확한 표고는 대가 길고 육질이 부드럽고 비교적 강수량이 높아 수분함량이 높은 것으로 알려져 있다. 이러한 현상은 표고의 수확 시기에 따라 기후, 온도, 강수량 등의 차이가 이화학적 특성에 큰 영향을 미치는 것으로 생각되어, 본 연구에서는 봄과 가을에 각각 표고를 수확하여 이화학적 특성 및 기능성성분을 비교하였다. 분석결과 가을에 수확한 표고가 봄에 수확한 표고에 비해 수분, β-glucan, ergosterol 그리고 ergothioneine 함량이 유의적으로 높게 나타나, 소재 개발 시에 경제적 경쟁력을 고려했을 때 가을에 수확한 표고 활용이 유리할 것으로 고려된다.

• Tuberculosis and Respiratory Diseases
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• v.39 no.1
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• pp.28-34
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• 1992

Background: Diffuse panbronchiolitis (DPB) is a chronic obstructive pulmonary disease distinguished from bronchial asthma, chronic bronchitis, pulmonary emphysema, bronchiectasis, or alveolitis. It is prevalent in Japan, but is known to be rare outside of Japan. Only a few cases in Chinese, Italian, Noirth American and Korean have been reported. During recent two years we have found 16 cases of DPB in Seoul National University Hospital and analyzed the clinical characteristics. Method: We reviewed the patients' age, sex, duration of illness, smoking history, occupational history and past medical history. And we analyzed patients' symptoms, physical signs, laboratory findings and responses to treatment. Results: 1) Male: female ratio was 2.2:1, the ages ranged from 27 to 72 years old, and the duration of disease varied from 1 to 20 years. 2) Most of the patients were being treated as bronchiectasis, miliary tuberculosis, chronic bronchitis or bronchial asthma before they were diagnosed as DPB. 3) Only one patient was a smoker, and 25% of patients had the occupational history of exposure to particles or gas. And all patients had paranasal sinusitis. 4) High resolution computed tomography (HRCT) was very useful in diagnosing the disease in most of the patients. 5) PFT showed obstructive and restrictive abnormalities, and blood gas revealed hypoxemia in most of the patients. 6) Pseudomonas aeruginosa was isolated in the sputum of four patients (25%). 7) The titers of cold hemaglutinin, RA factor and CRP were elevated in most of the patients. 8) Most of the patients improved after treatment with erythromycin. Conclusion: DPB might not be a rare disease in Korea. So DPB should be suspected in a patient who has chronic cough, sputum, dyspnea and diffuse fine nodular chest X-ray abnormality. HRCT and open lung biopsy should be considered in a patient suspected of DPB.

• Pediatric Infection and Vaccine
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• v.23 no.2
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• pp.87-93
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• 2016

Purpose: An outbreak of influenza virus is uncommon in neonatal intensive care unit (NICU). The clinical presentation of influenza virus infection in neonates is diverse. This study was aimed to report an outbreak of influenza A in a NICU and to investigate the clinical characteristics of influenza virus infection in neonates especially preterm infants during the 2011-2012 influenza season in Korea. Methods: We reviewed the medical records of 29 patients who were evaluated by respiratory virus multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) at NICU of Kosin University Gospel Hospital during the 2011-2012 seasonal influenza outbreak in Korea. Results: Eleven patients (37.9%) were influenza A virus RT-PCR positive during the survey periods. They were all preterm infants and three of them had no symptoms. Eight patients had symptoms and it was fever (18%, 2/11), respiratory difficulty (72.7%, 8/11) without symptoms of upper respiratory infection, and gastrointestinal symptoms (27.3%, 3/11). The median duration of symptom was 5 days. There were differences of duration of admission at the test of respiratory RT-PCR, Clinical Risk Index for Babies (CRIB) score, use of mechanical ventilation, and use of dexamethasone before infection between influenza A virus RT-PCR positive and negative group. All 11 patients with influenza A were discharged without any complications. Conclusions: The symptoms of influenza A virus infection in the preterm infants is nonspecific. Influenza A virus should be considered as a possible cause of infection in NICU during the influenza season in the community.

• Journal of Music and Human Behavior
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• v.9 no.1
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• pp.37-53
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• 2012

This study is conducted to analyse the process and the pattern of motivation for musical expression in clinical music therapy for the adults in the mental health center. The participant were 8 adults purposive sampling who had more than one year music therapy experience in the mental health center and their age ranged from 27 to 53. A major category derived and analysed from the grounded theory method by Strauss and Corbin. The qualitative analysis indicated that motivation for musical expression in music therapy, which was the central phenomenon in this study, was determined by the music therapist and songs used in the sessions. The central phenomenon was caused by the therapist's friendly attitude, high musical capacity, the familarity of the selected songs and the significancy of the lyrics of selected songs. The levels of reliability about the therapist's personality and musical ability as a professional music therapist and the positive arousal of the songs used in sessions affected as the contextual condition. Spontaneous musical expression in music therapy brought the escape from reality, release of stress and sharing by the intervening condition 'empathy' and this resulted in mood regulation, the instillation of hope and group cohesion. It has been found that there were three types of motivation in music therapy: intrinsic motivation, relationship dependent extrinsic motivation and evasive motivation.